دورية أكاديمية
Comparing the Effect of Alendronate and Vitamin D Administration on Lumbosacral Fusion and Severity of Low Back Pain in Patients After Posterior Lumbar Fusion Surgery: A Randomized Clinical Trial
| العنوان: | Comparing the Effect of Alendronate and Vitamin D Administration on Lumbosacral Fusion and Severity of Low Back Pain in Patients After Posterior Lumbar Fusion Surgery: A Randomized Clinical Trial |
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| المؤلفون: | Sajad Shafiee, Saeed Ehteshami, Kaveh Haddadi, Siavash Moradi, Mojtaba Salah Ahangar, Maryam Hasannezhad Reskati, Misagh Shafizad |
| المصدر: | Journal of Mazandaran University of Medical Sciences, Vol 31, Iss 196, Pp 36-43 (2021) |
| بيانات النشر: | Mazandaran University of Medical Sciences, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | alendronate, vitamin d, vertebral fusion, posterior spinal fusion surgery, low back pain, Medicine, Medicine (General), R5-920 |
| الوصف: | Background and purpose: Bone fusion is a dynamic process and availability of calcium and balance of vitamin D can be effective in post spinal cord fusion. There are contradictory results on this issue, so, we decided to compare the effect of administration of vitamin D and alendronate on lumbosacral vertebral fusion in patients undergoing posterior spinal fusion surgery. Materials and methods: A single-blind clinical trial was carried out in 75 patients. Patients were divided into three groups (n=25 per group) using block randomization: Alendronate group who received 70 mg oral alendronate every two weeks, Vitamin D group to receive vitamin D 50,000 units per month for six months, and control group who received routine treatment after the surgery. After six months, the patients underwent CT scan of the lumbar region for clinical assessment of lumbar fusion. Pain intensity was assessed using Visual Analogue Scale (VAS), one and six months after the surgery. Data analysis was performed in SPSS V16. Results: Before surgery, pain intensity was higher in vitamin D group (6.36 ± 1.3) than the controls and alendronate group (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Persian |
| تدمد: | 1735-9260 1735-9279 |
| العلاقة: | http://jmums.mazums.ac.ir/article-1-14953-en.htmlTest; https://doaj.org/toc/1735-9260Test; https://doaj.org/toc/1735-9279Test |
| الوصول الحر: | https://doaj.org/article/cd0e067221bc445fbfa79fbbdfc02057Test |
| رقم الانضمام: | edsdoj.0e067221bc445fbfa79fbbdfc02057 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17359260 17359279 |
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