Use of Connected Pen as a Diagnostic Tool to Evaluate Missed Bolus Dosing Behavior in People with Type 1 and Type 2 Diabetes
| العنوان: | Use of Connected Pen as a Diagnostic Tool to Evaluate Missed Bolus Dosing Behavior in People with Type 1 and Type 2 Diabetes |
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| المؤلفون: | Howard Wolpert, Eric S. Meadows, Stephanie Edwards, Xuanyao He, Wenjie Wang, Jennal Johnson, David Price, Jiat-Ling Poon, William H. Polonsky |
| المصدر: | Diabetes Technology & Therapeutics |
| بيانات النشر: | Mary Ann Liebert, Inc., publishers, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Adult, Blood Glucose, Male, genetic structures, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, Connected pen, Endocrinology, Bolus (medicine), Diabetes mellitus, medicine, Humans, Hypoglycemic Agents, Dosing, Continuous glucose monitoring, Glycated Hemoglobin, business.industry, Blood Glucose Self-Monitoring, nutritional and metabolic diseases, Original Articles, Middle Aged, medicine.disease, Medical Laboratory Technology, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Anesthesia, Missed bolus dose, Female, business |
| الوصف: | Objective: This study used connected pen to determine missed bolus dose (MBD) frequency during masked and unmasked continuous glucose monitoring (CGM) periods and examined its link with time-in-range (TIR), time-above-range (TAR), time-below-range (TBR), and key participant characteristics in people with diabetes. Methods: This was a 12-week, single-arm, exploratory, two-period study for people with type 1 diabetes (T1D) or type 2 diabetes (T2D). The primary objective was to estimate the average number of MBD during masked and real-time CGM use. The secondary objective was to estimate the average percent TIR and its relationship to MBD. An exploratory objective was to investigate the participant characteristics that were associated with MBD. Data were analyzed for differences in MBD by diabetes type and other participant characteristics, by CGM period, and by hypoglycemic fear scores. Results: Participants (n = 64; T1D, n = 38; T2D, n = 26) were 48 ± 11.9 years old and 44% were female. From the masked to the unmasked period, MBD, %TAR, %TBR, and glycated hemoglobin decreased significantly (0.74 MBD/day to 0.62 MBD/day, P = 0.008; 53.6%–48.1%, P = 0.004; 4.49%–2.93%, P |
| اللغة: | English |
| تدمد: | 1557-8593 1520-9156 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf5ba04ddb62663930ea2e257d5da67Test http://europepmc.org/articles/PMC8783630Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8bf5ba04ddb62663930ea2e257d5da67 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15578593 15209156 |
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