دورية أكاديمية

Prevalence of clinical electroencephalography findings in stroke patients with delirium.

التفاصيل البيبلوغرافية
العنوان: Prevalence of clinical electroencephalography findings in stroke patients with delirium.
المؤلفون: Mintz, Noa B.1 (AUTHOR), Andrews, Nicholas1 (AUTHOR), Pan, Kelly1 (AUTHOR), Bessette, Eric1 (AUTHOR), Asaad, Wael F.2,3,4,5 (AUTHOR), Sherif, Mohamed4,5,6 (AUTHOR), Rubinos, Clio7 (AUTHOR), Mahta, Ali1,2,5 (AUTHOR), Girard, Timothy D.8 (AUTHOR), Reznik, Michael E.1,2,4,5,8 (AUTHOR) michael.reznik@pitt.edu
المصدر: Clinical Neurophysiology. Jun2024, Vol. 162, p229-234. 6p.
مصطلحات موضوعية: *STROKE patients, *DELIRIUM, *ELECTROENCEPHALOGRAPHY, *BRAIN damage, *BRAIN diseases, *EPILEPSY
مستخلص: • On days with delirium, stroke patients had more generalized EEG abnormalities, even when excluding those with anesthetic use. • Delirious stroke patients had fewer focal EEG abnormalities, though these differences were not significant. • These findings may reinforce the diffuse nature of delirium, even in patients with structural brain lesions. Delirium is an acute cognitive disorder associated with multiple electroencephalographic (EEG) abnormalities in non-neurological patients, though specific EEG characteristics in patients with stroke remain unclear. We aimed to compare the prevalence of EEG abnormalities in stroke patients during delirium episodes with periods that did not correspond to delirium. We retrospectively analyzed clinical EEG reports for stroke patients who received daily delirium assessments as part of a prospective study. We compared the prevalence of EEG features corresponding to patient-days with vs. without delirium, including focal and generalized slowing, and focal and generalized epileptiform abnormalities (EAs). Among 58 patients who received EEGs, there were 192 days of both EEG and delirium monitoring (88% [n = 169] corresponding to delirium). Generalized slowing was significantly more prevalent on days with vs. without delirium (96% vs. 57%, p = 0.03), as were bilateral or generalized EAs (38% vs. 13%, p = 0.03). In contrast, focal slowing (53% vs. 74%, p = 0.11) and focal EAs were less prevalent on days with delirium (38% vs. 48%, p = 0.37), though these differences were not statistically significant. We found a higher prevalence of generalized but not focal EEG abnormalities in stroke patients with delirium. These findings may reinforce the diffuse nature of delirium-associated encephalopathy, even in patients with discrete structural lesions. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:13882457
DOI:10.1016/j.clinph.2024.03.004