المؤلفون: Cho, Byoung Chul, Kim, Dong-Wan, Spira, Alexander I, Gomez, Jorge E, Haura, Eric B, Kim, Sang-We, Sanborn, Rachel E, Cho, Eun Kyung, Lee, Ki Hyeong, Minchom, Anna, Lee, Jong-Seok, Han, Ji-Youn, Nagasaka, Misako, Sabari, Joshua K, Ou, Sai-Hong Ignatius, Lorenzini, Patricia, Bauml, Joshua M, Curtin, Joshua C, Roshak, Amy, Gao, Grace, Xie, John, Thayu, Meena, Knoblauch, Roland E, Park, Keunchil

المصدر: Nature Medicine. 29(10)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Clinical Trials and Supportive Activities, Lung, Lung Cancer, Clinical Research, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, 6.2 Cellular and gene therapies, Humans, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Prospective Studies, Protein Kinase Inhibitors, Mutation, Aniline Compounds, ErbB Receptors, Medical and Health Sciences, Immunology, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1s33k5j3Test

المؤلفون: Emily Alger, Mary Van Zyl, Olalekan Lee Aiyegbusi, Dave Chuter, Lizzie Dean, Anna Minchom, Christina Yap

المصدر: Research Involvement and Engagement, Vol 10, Iss 1, Pp 1-9 (2024)

مصطلحات موضوعية: Patient-Reported Outcomes, Dose-finding, Phase I, Trial design, Patient engagement, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2056-7529Test

الوصول الحر: https://doaj.org/article/a5cb45ec14b9497e9b1481114ed722e1Test

المؤلفون: Viteri, Santiago, Minchom, Anna, Bazhenova, Lyudmila, Ou, Sai‐Hong Ignatius, Bauml, Joshua M, Shell, Scott A, Schaffer, Michael, Gu, Junchen, Rose, Jennifer B, Curtin, Joshua C, Mahadevia, Parthiv, Girard, Nicolas

المصدر: Molecular Oncology. 17(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Genetics, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Humans, Lung Neoplasms, Mutagenesis, Insertional, ErbB Receptors, Mutation, Exons, Genomics, Protein Kinase Inhibitors, EGFR, Exon 20 insertion mutations, NGS, NSCLC, PCR, Oncology & Carcinogenesis, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1hq456d2Test

المؤلفون: Mary Van Zyl, Anne Barell, Bridget Cooley, Janet Hanwell, Josie Parlak, Udai Banerji, Johann De Bono, Adam Sharp, Juanita Lopez, Nicolo Matteo Luca Battisti, Anna Minchom

المصدر: Cancer Reports, Vol 7, Iss 6, Pp n/a-n/a (2024)

مصطلحات موضوعية: clinical trial, geriatric assessment, phase I, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2573-8348Test

الوصول الحر: https://doaj.org/article/898ed05cc677458a94115355b7e29a02Test

المؤلفون: Rannikko, JH, Verlingue, L, de Miguel, M, Pasanen, A, Robbrecht, D, Skytta, T, Iivanainen, S, Shetty, S, Ma, YT, Graham, DM, Arora, SP, Jaakkola, P, Yap, C, Xiang, Y, Mandelin, J, Karvonen, MK, Jalkanen, J, Karaman, S, Koivunen, JP, Minchom, A, Hollmén, M, Bono, P

المساهمون: Yap, Christina, Minchom, Anna

مصطلحات موضوعية: Clever-1, GeoMx, Stabilin-1, cancer, first-in-man, immune activation, Humans, Melanoma, Macrophage Activation, Skin Neoplasms, Antibodies, Monoclonal, Humanized

جغرافية الموضوع: United States

وصف الملف: Print-Electronic; application/pdf

العلاقة: 101307; S2666-3791(23)00501-3; Cell Reports Medicine, 2023, 4 (12), pp. 101307 -; https://repository.icr.ac.uk/handle/internal/6097Test

الإتاحة: https://doi.org/10.1016/j.xcrm.2023.101307Test
https://repository.icr.ac.uk/handle/internal/6097Test

المؤلفون: Rannikko, Jenna H., Verlingue, Loic, de Miguel, Maria, Pasanen, Annika, Robbrecht, Debbie, Skytta, Tanja, Iivanainen, Sanna, Shetty, Shishir, Ma, Yuk Ting, Graham, Donna M., Arora, Sukeshi Patel, Jaakkola, Panu, Yap, Christina, Xiang, Yujuan, Mandelin, Jami, Karvonen, Matti K., Jalkanen, Juho, Karaman, Sinem, Koivunen, Jussi P., Minchom, Anna, Hollmén, Maija, Bono, Petri

المساهمون: HUS Comprehensive Cancer Center, Department of Oncology, Research Programs Unit, INDIVIDRUG - Individualized Drug Therapy, Organotypic Vasculature Lab, Medicum, Heikki Joensuu / Principal Investigator

مصطلحات موضوعية: cancer, Clever-1, first-in-man, GeoMx, immune activation, Stabilin-1, 3122 Cancers

وصف الملف: application/pdf

العلاقة: We thank the study participants, the investigators, and the research team who contributed to the study. We also want to thank Mari Parsama, Teija Kanasuo, Riikka Sjöroos, Sari Mäki, and Maritta Pohjansalo for excellent technical assistance. GeoMx Digital Spatial Profiling was performed at FIMM Single-Cell Analytics and Sequencing units supported by HiLIFE and Biocenter Finland. This study was funded by Faron Pharmaceuticals (Turku, Finland), European Union’s Horizon 2020 research and innovation program (ID: 960914 ), the Academy of Finland (M.H.), Business Finland (M.H.), Cancer Society of Finland (M.H. and J.H.R.), the Sigrid Jusélius Foundation (M.H.), Orion Research Foundation (J.H.R.), and the Paulo Foundation (J.H.R.). The graphical abstract was created with BioRender.; Rannikko , J H , Verlingue , L , de Miguel , M , Pasanen , A , Robbrecht , D , Skytta , T , Iivanainen , S , Shetty , S , Ma , Y T , Graham , D M , Arora , S P , Jaakkola , P , Yap , C , Xiang , Y , Mandelin , J , Karvonen , M K , Jalkanen , J , Karaman , S , Koivunen , J P , Minchom , A , Hollmén , M & Bono , P 2023 , ' Bexmarilimab-induced macrophage activation leads to treatment benefit in solid tumors : The phase I/II first-in-human MATINS trial ' , Cell Reports Medicine , vol. 4 , no. 12 , 101307 . https://doi.org/10.1016/j.xcrm.2023.101307Test; ORCID: /0000-0002-0719-1773/work/152352323; 85180535694; 7764d7f5-6cbc-417a-9d48-5cd3a7e8d8ba; http://hdl.handle.net/10138/570651Test; 001141085500001

الإتاحة: http://hdl.handle.net/10138/570651Test

المؤلفون: John, A., McMahon, D.J., Chauhan, D.D., Mullings, S., Samuel, N., Milner-Watts, C., Tokaca, N., Yousaf, N., Davidson, M., Bhosle, J., Minchom, A.R., O'Brien, M.E.R., Popat, S.

المصدر: ESMO Open ; volume 9, page 102619 ; ISSN 2059-7029

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1016/j.esmoop.2024.102619Test
https://api.elsevier.com/content/article/PII:S2059702924003879?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2059702924003879?httpAccept=text/plainTest

المؤلفون: Leighl, N., Minchom, A.R., Lee, K.H.H., Krebs, M.G., Cho, B.C., Kim, Y.J., Johnson, M.L., Sabari, J., Sanusi, B., Alhadab, A., Haddish-Berhane, N., Zemlickis, D., Mitselos, A., Collins, C., Baig, M., Bauml, J.M., Knoblauch, R.E., Hellemans, P., Sanborn, R.E.

المساهمون: Johnson & Johnson Innovative Medicine

المصدر: ESMO Open ; volume 9, page 102585 ; ISSN 2059-7029

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1016/j.esmoop.2024.102585Test
https://api.elsevier.com/content/article/PII:S2059702924003533?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2059702924003533?httpAccept=text/plainTest

المؤلفون: Minchom, A.R., Gilding, N., Tan, V., Christoforou, K., Rule, J., Aziez, A., Gomes, F., Januszewski, A.

المصدر: ESMO Open ; volume 9, page 102672 ; ISSN 2059-7029

مصطلحات موضوعية: Cancer Research, Oncology

الإتاحة: https://doi.org/10.1016/j.esmoop.2024.102672Test
https://api.elsevier.com/content/article/PII:S205970292400440X?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S205970292400440X?httpAccept=text/plainTest

المؤلفون: Shybi Mohamedkhan, Sumeet Hindocha, James de Boisanger, Thomas Millard, Liam Welsh, Philip Rich, Andrew D. MacKinnon, Nicholas Williams, Bhupinder Sharma, Nicola Rosenfelder, Anna Minchom

المصدر: Cancers, Vol 16, Iss 6, p 1218 (2024)

مصطلحات موضوعية: contrast clearance analysis, non-small cell lung cancer, brain metastases, radionecrosis, stereotactic radiosurgery, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/2072-6694/16/6/1218Test; https://doaj.org/toc/2072-6694Test

الوصول الحر: https://doaj.org/article/d6ab8b0af97d43858feccf8cea7ce758Test