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1دورية أكاديمية
المؤلفون: Gutierrez, Jahir M, Feizi, Amir, Li, Shangzhong, Kallehauge, Thomas B, Hefzi, Hooman, Grav, Lise M, Ley, Daniel, Baycin Hizal, Deniz, Betenbaugh, Michael J, Voldborg, Bjorn, Faustrup Kildegaard, Helene, Min Lee, Gyun, Palsson, Bernhard O, Nielsen, Jens, Lewis, Nathan E
المصدر: Nature communications. 11(1)
مصطلحات موضوعية: CHO Cells, Animals, Mammals, Humans, Cricetulus, Mice, Proteins, Recombinant Proteins, Reproducibility of Results, Genome, Computer Simulation, Bone Morphogenetic Protein 2, Secretory Pathway, Gene Knockdown Techniques, Vaccine Related, Prevention, Biodefense, Biotechnology, 1.1 Normal biological development and functioning, Generic health relevance
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/6x51w8qmTest
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2دورية أكاديمية
المؤلفون: Sergeeva, Daria, Min Lee, Gyun, Nielsen, Lars Keld, Grav, Lise Marie
المصدر: Sergeeva , D , Min Lee , G , Nielsen , L K & Grav , L M 2020 , ' Multicopy Targeted Integration for Accelerated Development of High-Producing Chinese Hamster Ovary Cells ' , ACS Synthetic Biology , vol. 9 , no. 9 , pp. 2546-2561 . https://doi.org/10.1021/acssynbio.0c00322Test
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1021/acssynbio.0c00322Test
https://orbit.dtu.dk/en/publications/71c01a2d-bfaf-4f2b-a221-1ef2dd777ca7Test
https://backend.orbit.dtu.dk/ws/files/258647007/Multicopy_TI_manuscript_revised_version.pdfTest -
3دورية أكاديمية
المؤلفون: Kol, Stefan, Ley, Daniel, Wulff, Tune, Decker, Marianne, Arnsdorf, Johnny, Schoffelen, Sanne, Hansen, Anders Holmgaard, Jensen, Tanja Lyholm, Gutierrez, Jahir M., Chiang, Austin W. T., Masson, Helen O., Palsson, Bernhard O., Voldborg, Bjørn Gunnar, Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup, Min Lee, Gyun, Lewis, Nathan E.
المصدر: Kol , S , Ley , D , Wulff , T , Decker , M , Arnsdorf , J , Schoffelen , S , Hansen , A H , Jensen , T L , Gutierrez , J M , Chiang , A W T , Masson , H O , Palsson , B O , Voldborg , B G , Pedersen , L E , Kildegaard , H F , Min Lee , G & Lewis , N E 2020 , ' Multiplex secretome engineering enhances recombinant protein production and purity ' , Nature Communications , vol. 11 , ....
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1038/s41467-020-15866-wTest
https://orbit.dtu.dk/en/publications/c440cd45-e242-4b63-9b03-861ba7d54bf2Test
https://backend.orbit.dtu.dk/ws/files/216678244/Kol_et_al_2020_Nature_Communications_2_.pdfTest -
4دورية أكاديمية
المؤلفون: Julie la Cour Karottki, Karen, Hefzi, Hooman, Xiong, Kai, Shamie, Isaac, Hansen, Anders Holmgaard, Li, Songyuan, Pedersen, Lasse Ebdrup, Li, Shangzhong, Lee, Jae Seong, Min Lee, Gyun, Kildegaard, Helene Faustrup, Lewis, Nathan E.
المصدر: Julie la Cour Karottki , K , Hefzi , H , Xiong , K , Shamie , I , Hansen , A H , Li , S , Pedersen , L E , Li , S , Lee , J S , Min Lee , G , Kildegaard , H F & Lewis , N E 2020 , ' Awakening dormant glycosyltransferases in CHO cells with CRISPRa ' , Biotechnology and Bioengineering , vol. 117 , no. 2 , pp. 593-598 . https://doi.org/10.1002/bit.27199Test
مصطلحات موضوعية: CHO, CRISPRa, Glycosylation, Mgat3, St6gal11
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1002/bit.27199Test
https://orbit.dtu.dk/en/publications/4ff27313-8f0d-44e4-b70c-6ab07c7adec8Test
https://backend.orbit.dtu.dk/ws/files/203289020/melju_Karottki_et_al_2019_Biotechnology_and_Bioengineering.pdfTest -
5دورية أكاديمية
المؤلفون: Amann, Thomas, Hansen, Anders Holmgaard, Kol, Stefan, Hansen, Henning Gram, Arnsdorf, Johnny, Nallapareddy, Saranya, Voldborg, Bjørn, Min Lee, Gyun, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup
المصدر: Amann , T , Hansen , A H , Kol , S , Hansen , H G , Arnsdorf , J , Nallapareddy , S , Voldborg , B , Min Lee , G , Andersen , M R & Kildegaard , H F 2019 , ' Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles ' , Metabolic Engineering , vol. 52 , pp. 143-152 . https://doi.org/10.1016/j.ymben.2018.11.014Test
مصطلحات موضوعية: Chinese hamster ovary (CHO) cells, CRISPR/Cas9, Glyco-engineering, Biotechnology, Multiplexing, Plasma proteins
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1016/j.ymben.2018.11.014Test
https://orbit.dtu.dk/en/publications/daf762f7-774f-40e4-a472-f8f6ca1fbf03Test
https://backend.orbit.dtu.dk/ws/files/161877733/20181030_A1AT_C1INH_manuscript_Final.pdfTest -
6دورية أكاديمية
المصدر: Kwang Ha , T , Hansen , A H , Kildegaard , H F & Min Lee , G 2019 , ' BiP Inducer X: An ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture ' , Biotechnology Journal . https://doi.org/10.1002/biot.201900130Test
مصطلحات موضوعية: BiP inducer X, Chinese hamster ovary (CHO) cells, endoplasmic reticulum (ER) stress inhibitors, galactosylation, monoclonal antibodies
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1002/biot.201900130Test
https://orbit.dtu.dk/en/publications/4bb8049c-8448-48b2-849a-893bbcc3e831Test
https://backend.orbit.dtu.dk/ws/files/186200289/Bip_inducer_X_an_ER_stress_inhibitor_for_enhancing_recombinant_antibody_production_in_CHO_cell_culture.pdfTest -
7دورية أكاديمية
المؤلفون: Xiong, Kai, Marquart, Kim Fabiano, Julie la Cour Karottki, Karen, Li, Shangzhong, Shamie, Isaac, Lee, Jae Seong, Gerling, Signe, Yeo, Nan Cher, Chavez, Alejandro, Min Lee, Gyun, Lewis, Nathan E, Kildegaard, Helene Faustrup
المصدر: Xiong , K , Marquart , K F , Julie la Cour Karottki , K , Li , S , Shamie , I , Lee , J S , Gerling , S , Yeo , N C , Chavez , A , Min Lee , G , Lewis , N E & Kildegaard , H F 2019 , ' Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference ' , Biotechnology and Bioengineering , vol. 116 , no. 7 , pp. 1813-1819 . https://doi.org/10.1002/bit.26969Test
مصطلحات موضوعية: Bak, Bax, CHO, CRISPRi, Casp3, apoptosis, caspase, mitochondrial membrane integrity
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1002/bit.26969Test
https://orbit.dtu.dk/en/publications/9329fad8-5da5-4ee5-a0bb-d0683cbf1434Test
https://backend.orbit.dtu.dk/ws/files/238800772/nihms_1018956.pdfTest -
8مؤتمر
المؤلفون: Amann, Thomas, Hansen, Anders Holmgaard, Pristovsek, Nusa, Singh, Ankita, Min Lee, Gyun, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup
المصدر: Amann , T , Hansen , A H , Pristovsek , N , Singh , A , Min Lee , G , Andersen , M R & Kildegaard , H F 2017 , ' CHO glyco-engineering using CRISPR/Cas9 multiplexing for protein production with homogeneous N-glycan profiles ' , 25th ESACT Meeting , Lausanne , Switzerland , 14/05/2017 - 17/05/2017 .
وصف الملف: application/pdf
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9دورية أكاديمية
المؤلفون: Amann, Thomas, Hansen, Anders Holmgaard, Kol, Stefan, Min Lee, Gyun, Andersen, Mikael Rørdam, Kildegaard, Helene Faustrup
المصدر: Amann , T , Hansen , A H , Kol , S , Min Lee , G , Andersen , M R & Kildegaard , H F 2018 , ' CRISPR/Cas9-multiplexed editing of Chinese hamster ovary B4Gal-T1, 2, 3 and 4 Tailors N -Glycan Profiles of Therapeutics and Secreted Host Cell Proteins ' , Biotechnology Journal , vol. 13 , no. 10 , 1800111 . https://doi.org/10.1002/biot.201800111Test
مصطلحات موضوعية: Chinese hamster ovary cells, CRISP/Cas9, Erythropoietin, Glycoengineering, Multiplexing, N‐glycosylation, Rituximab
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1002/biot.201800111Test
https://orbit.dtu.dk/en/publications/9615dda9-824f-44dc-945a-6dbf6dc22600Test
https://backend.orbit.dtu.dk/ws/files/179420524/180217_B4GalT_KO_manuscript.pdfTest -
10دورية أكاديمية
المؤلفون: Noh, Soo Min, Shin, Seunghyeon, Min Lee, Gyun
المصدر: Noh , S M , Shin , S & Min Lee , G 2018 , ' Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies ' , Scientific Reports , vol. 8 , 5361 . https://doi.org/10.1038/s41598-018-23720-9Test
مصطلحات موضوعية: Metabolic engineering, Recombinant protein therapy, Reverse transcription polymerase chain reaction
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1038/s41598-018-23720-9Test
https://orbit.dtu.dk/en/publications/c3748c8e-d76f-40e3-8fcb-c291becc3057Test
https://backend.orbit.dtu.dk/ws/files/146252786/Comprehensive.pdfTest
