A case of neurosarcoidosis with necrotizing granuloma expressing angiotensin-converting enzyme
| العنوان: | A case of neurosarcoidosis with necrotizing granuloma expressing angiotensin-converting enzyme |
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| المؤلفون: | Seiko Kitamura, Shuichi Kaneko, Kengo Furuichi, Miki Tomokage, Mitsutoshi Nakada, Takashi Wada, Akinori Hara, Norihiko Sakai, Kiyoki Kitagawa, Yoh Zen, Shinji Kitajima |
| المصدر: | Modern Rheumatology. 20(5):506-510 |
| بيانات النشر: | Japan College of Rheumatology = 日本リウマチ学会, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Pathology, Necrosis, Sarcoidosis, Necrotizing sarcoid granuloma, Radiography, Peptidyl-Dipeptidase A, Neurosarcoidosis, Young Adult, Rheumatology, Central Nervous System Diseases, hemic and lymphatic diseases, medicine, Humans, Pathological, Epilepsy, Granuloma, biology, medicine.diagnostic_test, business.industry, Brain, Angiotensin-converting enzyme, Magnetic resonance imaging, medicine.disease, Magnetic Resonance Imaging, biology.protein, Immunohistochemistry, Radiography, Thoracic, Lymph Nodes, Radiology, Neurosurgery, medicine.symptom, Tomography, X-Ray Computed, business |
| الوصف: | 金沢大学医薬保健研究域医学系 We described a case of neurosarcoidosis with necrotizing sarcoid granulomatosis in a 22-year-old man. Contrast-enhanced brain computed tomography scan and magnetic resonance imaging showed intracerebral multiple nodular lesions. Noncaseating and partial necrotizing granulomas were detected in the specimen resected by neurosurgery. In addition, immunohistochemical examination revealed the expression of angiotensin-converting enzyme in necrotizing granuloma. Thus, these findings were consistent with neurosarcoidosis. Clinical and pathological presentation, immunological features, and treatment modalities of neurosarcoidosis are discussed. © 2010 Japan College of Rheumatology. This is the pre-peer reviewed version of the following article: [Full cite], which has been published in final form at [link to final article]. |
| اللغة: | English |
| تدمد: | 1439-7595 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a8f81273375344f18ffe2dd30967acTest http://hdl.handle.net/2297/25880Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....04a8f81273375344f18ffe2dd30967ac |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14397595 |
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