المؤلفون: Mark J. Wall, Emily Hill, Robert Huckstepp, Kerry Barkan, Giuseppe Deganutti, Michele Leuenberger, Barbara Preti, Ian Winfield, Sabrina Carvalho, Anna Suchankova, Haifeng Wei, Dewi Safitri, Xianglin Huang, Wendy Imlach, Circe La Mache, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, Fei-Yue Zhao, David Spanswick, Christopher A. Reynolds, Martin Lochner, Graham Ladds, Bruno G. Frenguelli

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/248fd0638f5942beb0219612bf9fe670Test

المؤلفون: Giuseppe Deganutti (2609257), Kerry Barkan (7438523), Barbara Preti (10015061), Michele Leuenberger (1399192), Mark Wall (2663167), Bruno G. Frenguelli (407629), Martin Lochner (1269384), Graham Ladds (430368), Christopher A. Reynolds (473093)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, G i protein complexed state, CPA, structure-based drug design, Agonist Binding Mechanism, binding, GPCR, 1 R, AR, adenosine, G protein-coupled receptors, 1 R agonists

العلاقة: https://figshare.com/articles/journal_contribution/Deciphering_the_Agonist_Binding_Mechanism_to_the_Adenosine_A1_Receptor/13621361Test

الإتاحة: https://doi.org/10.1021/acsptsci.0c00195.s001Test

المؤلفون: Barbara, Preti, Anna, Suchankova, Giuseppe, Deganutti, Michele, Leuenberger, Kerry, Barkan, Iga, Manulak, Xianglin, Huang, Sabrina, Carvalho, Graham, Ladds, Martin, Lochner

المصدر: Journal of medicinal chemistry. 65(21)

مصطلحات موضوعية: Structure-Activity Relationship, Adenosine, Halogens, Purinergic P1 Receptor Agonists, Receptors, Purinergic P1, Animals, Humans, Adenosine-5'-(N-ethylcarboxamide), Rats

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::1fef5ba6c4d64e47165cbcd7955c7afdTest
https://pubmed.ncbi.nlm.nih.gov/36270633Test

المؤلفون: DT Vu, Michele Leuenberger, Emilie Reber, Zeno Stanga, K.A. Schönenberger

المصدر: 20. Dreiländertagung der Gesellschaft für Klinische Ernährung der Schweiz (GESKES) dem Schweizerischen Verband der Ernährungsberater/innen (SVDE) der Deutschen Gesellschaft für Ernährungsmedizin e.V. (DGEM) der Österreichischen Arbeitsgemeinschaft Klinische Ernährung (AKE) Abstracts, sortiert nach freien Vorträgen und E-Postern, welche nach Themengruppen sortiert sind.

مصطلحات موضوعية: medicine.medical_specialty, Parenteral nutrition, business.industry, medicine, eHealth, Intensive care medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::687bca5b30aed6f045e032c7795535c5Test
https://doi.org/10.1055/s-0041-1729698Test

المؤلفون: Michele Leuenberger, E Aubry, Natalie Friedli, Jessica Stirnimann, Philipp Schütz, Carla Aeberhard, Zeno Stanga

المصدر: Aktuelle Ernährungsmedizin. 44:33-42

مصطلحات موضوعية: Gynecology, medicine.medical_specialty, Nutrition and Dietetics, business.industry, medicine, Medicine (miscellaneous), 610 Medicine & health, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d16d98c0d24b5532ad6152cea3332b0Test
https://doi.org/10.1055/a-0604-7900Test

المؤلفون: Manfred Heller, Marc-David Ruepp, Sanjeev Kumar V. Vernekar, Sophie Braga-Lagache, Michele Leuenberger, Martin Lochner, Thomas Jack, Andrew J. Thompson

المصدر: ACS Chemical Neuroscience. 10:438-450

مصطلحات موضوعية: 0303 health sciences, biology, Physiology, Cognitive Neuroscience, Cell Biology, General Medicine, Granisetron, Biochemistry, Neurotransmitter binding, 5-HT3 receptor, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Structural biology, Docking (molecular), medicine, biology.protein, Biophysics, Binding site, Receptor, 030217 neurology & neurosurgery, Ion channel, 030304 developmental biology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1d3459323c4bdc3a47152f9943664b82Test
https://doi.org/10.1021/acschemneuro.8b00327Test

المؤلفون: Barbara Preti, Bruno G. Frenguelli, Christopher A. Reynolds, Martin Lochner, Mark J. Wall, Kerry Barkan, Michele Leuenberger, Graham Ladds, Giuseppe Deganutti

المساهمون: Ladds, Graham [0000-0001-7320-9612], Apollo - University of Cambridge Repository

المصدر: ACS Pharmacol Transl Sci
Deganutti, Giuseppe; Barkan, Kerry; Preti, Barbara; Leuenberger, Michele; Wall, Mark; Frenguelli, Bruno G.; Lochner, Martin; Ladds, Graham; Reynolds, Christopher A. (22 October 2020). Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2020.10.22.350827 <http://dx.doi.org/10.1101/2020.10.22.350827Test>

مصطلحات موضوعية: Agonist, binding, medicine.drug_class, Gi alpha subunit, 610 Medicine & health, GPCRs, G protein coupled receptors, Adenosine A1 receptor, mutagenesis experiments, 540 Chemistry, medicine, Pharmacology (medical), SuMD, Receptor, G protein-coupled receptor, Pharmacology, Effector, Chemistry, adenosine A1 receptor, Adenosine receptor, QP, Regadenoson, Cell biology, supervised molecular dynamics, 570 Life sciences, biology, A(1)R, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18be872306b6a5746378ca500e68e59fTest
https://europepmc.org/articles/PMC7887845Test/

المؤلفون: Kaspar Staub, Stefan Mühlebach, Philipp Schuetz, Michele Leuenberger, Emilie Reber, Claude Pichard, Anastasia Stanga, Zeno Stanga, Katja A. Schönenberger

المساهمون: University of Zurich, Reber, Emilie

المصدر: Annals of nutrition & metabolism, Vol. 77, No 1 (2021) pp. 46-55

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Pediatrics, medicine.medical_specialty, Catheters, medicine.medical_treatment, Medicine (miscellaneous), 610 Medicine & health, 030209 endocrinology & metabolism, 03 medical and health sciences, 0302 clinical medicine, Quality of life, Humans, Medicine, Prospective Studies, Prospective cohort study, Aged, ddc:616, Home parenteral nutrition, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Mortality rate, 2701 Medicine (miscellaneous), Middle Aged, Parenteral nutrition, Short bowel syndrome, medicine.disease, Intestinal Diseases, Logistic Models, Catheter-Related Infections, 11294 Institute of Evolutionary Medicine, 2916 Nutrition and Dietetics, Female, Observational study, Parenteral Nutrition, Home, business, Complication, Central venous catheter, Switzerland

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d4d50b5a0d9542e6418aba76c2866dTest

المؤلفون: Adriana Euler, Stephanie Häusler, Martin Lochner, Vera Höhn, Michele Leuenberger, Bruno Stieger

المساهمون: University of Zurich

المصدر: Leuenberger, Michele; Häusler, Stephanie; Höhn, Vera; Euler, Adriana; Stieger, Bruno; Lochner, Martin (2021). Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters. Journal of pharmacology and experimental therapeutics, 377(3), pp. 346-357. American Society for Pharmacology and Experimental Therapeutics 10.1124/jpet.120.000449 <http://dx.doi.org/10.1124/jpet.120.000449Test>

مصطلحات موضوعية: 0301 basic medicine, ATP Binding Cassette Transporter, Subfamily B, Organic anion transporter 1, medicine.drug_class, Organic Anion Transporters, 610 Medicine & health, digestive system, Bile Acids and Salts, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Chenodeoxycholic acid, 540 Chemistry, medicine, Pharmacology, Bile acid, biology, Transporter, Bile Salt Export Pump, 030104 developmental biology, Biochemistry, chemistry, 10199 Clinic for Clinical Pharmacology and Toxicology, biology.protein, Hepatocytes, Molecular Medicine, 570 Life sciences, Liver function, Efflux, 030217 neurology & neurosurgery, Organic anion

وصف الملف: jpet.120.000449.full.pdf - application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b09bab5cd6da29d296d607c5a1fe2d7Test

المؤلفون: Mark J, Wall, Emily, Hill, Robert, Huckstepp, Kerry, Barkan, Giuseppe, Deganutti, Michele, Leuenberger, Barbara, Preti, Ian, Winfield, Sabrina, Carvalho, Anna, Suchankova, Haifeng, Wei, Dewi, Safitri, Xianglin, Huang, Wendy, Imlach, Circe, La Mache, Eve, Dean, Cherise, Hume, Stephanie, Hayward, Jess, Oliver, Fei-Yue, Zhao, David, Spanswick, Christopher A, Reynolds, Martin, Lochner, Graham, Ladds, Bruno G, Frenguelli

المصدر: Nature communications. 13(1)

مصطلحات موضوعية: Adenosine, Depression, Receptors, Purinergic P1, Analgesia, Receptors, G-Protein-Coupled

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::6aa941f335f351aaf8baa573ea9efddcTest
https://pubmed.ncbi.nlm.nih.gov/35851064Test