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1دورية أكاديمية
المؤلفون: Esther C. Y. Lee (10586857), Andrew J. McRiner (2512648), Katy E. Georgiadis (10756246), Julie Liu (6557627), Zooey Wang (10756249), Andrew D. Ferguson (1427719), Benjamin Levin (10185539), Moritz von Rechenberg (10586875), Christopher D. Hupp (2377594), Michael I. Monteiro (10586860), Anthony D. Keefe (3622769), Allison Olszewski (2671783), Charles J. Eyermann (1667878), Paolo Centrella (10756252), Yanbin Liu (231378), Shilpi Arora (130546), John W. Cuozzo (1665235), Ying Zhang (40767), Matthew A. Clark (1370337), Christelle Huguet (8932838), Anna Kohlmann (1417150)
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Ecology, Inorganic Chemistry, Hematology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, DNA-Encoded Chemical Library Screen., SAR, carboxylic acid-containing compounds, hydroxy acid oxidase 1, DNA-Encoded Chemical Library, PK, PH, novel chemical series, non-acid-containing HAO 1 inhibitors, HAO 1 inhibitors, Compound 5, potency, AGXT, exploration, DECL, ADME, Structure-based drug design
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2دورية أكاديمية
المؤلفون: Jeremy S. Disch (1960423), Jennifer M. Duffy (10586854), Esther C. Y. Lee (10586857), Diana Gikunju (8932826), Betty Chan (1342416), Benjamin Levin (10185539), Michael I. Monteiro (10586860), Sarah A. Talcott (10586863), Anthony C. Lau (10586866), Fei Zhou (86034), Anton Kozhushnyan (10586869), Neil E. Westlund (10586872), Patrick B. Mullins (1601887), Yan Yu (56143), Moritz von Rechenberg (10586875), Junyi Zhang (290426), Yelena A. Arnautova (2710522), Yanbin Liu (231378), Ying Zhang (40767), Andrew J. McRiner (2512648), Anthony D. Keefe (3622769), Anna Kohlmann (1417150), Matthew A. Clark (1370337), John W. Cuozzo (1665235), Christelle Huguet (8932838), Shilpi Arora (130546)
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Cancer, Plant Biology, Chemical Sciences not elsewhere classified, Click chemistry synthesis, Bispecific Estrogen Receptor α Degr., novel PROTAC binding features, screening, ER α, breast cancer, ER α WT, novel bispecific degrader, bispecific nanomolar degraders, nanomolar ER α binding, alkyne E 3 ligase engagers panel, MCF 7 tumor growth, DNA-encoded chemical library, molecule exemplar 7, DECL, DNA-Encoded Chemical Library Screen., mouse xenograft model, GOF
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3دورية أكاديمية
المؤلفون: Alexander Litovchick, Xia Tian, Michael I. Monteiro, Kaitlyn M. Kennedy, Marie-Aude Guié, Paolo Centrella, Ying Zhang, Matthew A. Clark, Anthony D. Keefe
المصدر: Molecules; Volume 24; Issue 10; Pages: 2026
مصطلحات موضوعية: DNA-encoded chemical library, affinity-mediated selection, G-quartet, c-myc, SPR
جغرافية الموضوع: agris
وصف الملف: application/pdf
العلاقة: Chemical Biology; https://dx.doi.org/10.3390/molecules24102026Test
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4
المؤلفون: Shilpi Arora, Anna Kohlmann, Christopher D. Hupp, Julie Liu, Christelle Huguet, Allison Olszewski, Moritz von Rechenberg, John W. Cuozzo, Ying Zhang, Katy E Georgiadis, Matthew A. Clark, Esther C.Y. Lee, Charles J. Eyermann, Andrew J. McRiner, Paolo A. Centrella, Michael I Monteiro, Anthony D. Keefe, Benjamin Levin, Andrew D. Ferguson, Zooey Wang, Yanbin Liu
المصدر: Journal of Medicinal Chemistry. 64:6730-6744
مصطلحات موضوعية: Male, Indoles, Crystallography, X-Ray, 01 natural sciences, Chemical library, Small Molecule Libraries, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Pharmacokinetics, Drug Discovery, Animals, Humans, Structure–activity relationship, Potency, Transaminases, 030304 developmental biology, ADME, 0303 health sciences, Oxidase test, Binding Sites, Chemistry, DNA, Metabolism, 0104 chemical sciences, Molecular Docking Simulation, Alcohol Oxidoreductases, Thiazoles, 010404 medicinal & biomolecular chemistry, Biochemistry, Drug Design, Hyperoxaluria, Primary, Molecular Medicine, Glucuronide, Half-Life
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecd410b881fad4a6d7e1db049c6ba5cTest
https://doi.org/10.1021/acs.jmedchem.0c02271Test -
5
المؤلفون: Anthony D. Keefe, Jeremy S. Disch, Jennifer Duffy, Esther C. Lee, Diana Gikunju, Betty Chan, Benjamin D. Levin, Michael I. Monteiro, Sarah A. Talcott, Anthony Lau, Fei Zhou, Anton Kozhushnyan, Neil E. Westlund, Patrick B. Mullins, Yan Yu, Moritz von Rechenberg, Junyi Zhang, Yelena Arnautova, Yanbin Liu, Ying Zhang, Andrew J. McRiner, Anna Kohlmann, Matthew A. Clark, John W. Cuozzo, Christelle Huguet, Shilpi Arora
المصدر: Cancer Research. 83:5346-5346
مصطلحات موضوعية: Cancer Research, Oncology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c39832f0b4b2f727dd1b73c76bcc701cTest
https://doi.org/10.1158/1538-7445.am2023-5346Test -
6
المؤلفون: Diana Gikunju, John W. Cuozzo, Yelena A Arnautova, Sarah A Talcott, Neil Westlund, Andrew J. McRiner, Anthony D. Keefe, Yan Yu, Christelle Huguet, Moritz von Rechenberg, Fei Zhou, Jennifer M Duffy, Shilpi Arora, Esther C.Y. Lee, Ying Zhang, Benjamin Levin, Matthew A. Clark, Jeremy S. Disch, Junyi Zhang, Yanbin Liu, Anton Kozhushnyan, Betty Chan, Anthony C Lau, Michael I Monteiro, Patrick B. Mullins, Anna Kohlmann
المصدر: Journal of Medicinal Chemistry. 64:5049-5066
مصطلحات موضوعية: Indoles, Cell Survival, Estrogen receptor, Breast Neoplasms, Chemical library, Small Molecule Libraries, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Animals, Humans, Structure–activity relationship, Aromatase, biology, Chemistry, DNA-encoded chemical library, Estrogen Antagonists, Estrogen Receptor alpha, DNA, Xenograft Model Antitumor Assays, Small molecule, Kinetics, Biochemistry, Click chemistry, biology.protein, Molecular Medicine, Click Chemistry, Female, Linker, Half-Life
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7302cad9922daa210279c4d6224ee0Test
https://doi.org/10.1021/acs.jmedchem.1c00127Test -
7
المؤلفون: Andrew D. Ferguson, Usha Narayanan, Christelle Huguet, John P Giulinger, Michael I Monteiro, Matthew A. Clark, Chris Hupp, Mortiz Von Rechenberg, Andrew J. McRiner, Kyle Denton, Anthony D. Keefe, John W. Cuozzo, Shilpi Arora, Sarah A Talcott, Diana Gikunju
المصدر: Molecular Cancer Therapeutics. 18:C049-C049
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Mutation, biology, Oncogene, Drug discovery, Chemistry, Mutant, Cancer, Computational biology, Hit to lead, medicine.disease, medicine.disease_cause, Small molecule, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, medicine, biology.protein, Bruton's tyrosine kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::264ca8cf52f2cf4205d1dd345f561dceTest
https://doi.org/10.1158/1535-7163.targ-19-c049Test -
8
المؤلفون: Eric S. Luth, Peter Juo, Benjamin J. Moss, Steven D. Garafalo, Emily Malkin, Michael I. Monteiro
المصدر: Molecular Biology of the Cell
مصطلحات موضوعية: Endosome, Endocytic cycle, Adaptor Protein Complex 2, Endocytosis, Nervous System, Clathrin, Animals, Genetically Modified, Animals, Receptors, AMPA, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Molecular Biology, Secretory pathway, biology, fungi, food and beverages, Signal transducing adaptor protein, Articles, Cell Biology, biology.organism_classification, Cell biology, Protein Transport, Gene Expression Regulation, Membrane Trafficking, Ventral nerve cord, Mutation, Synapses, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccb604880e1e94e3e1b10e70461b6a9Test
https://doi.org/10.1091/mbc.e14-06-1048Test -
9
المؤلفون: Lynette A. Fouser, Yanbin Liu, Junyi Zhang, Diana Gikunju, Jannik N. Andersen, Zooey Wang, Heather A. Thomson, Michael Briskin, Anthony D. Keefe, Dawn M. Troast, Ragunath Chandran, Christopher D. Hupp, Neil Westlund, Moritz von Rechenberg, Ying Zhang, Daniel I. Resnicow, Andrew J. McRiner, Kaan Certel, Julie Liu, Allison Olszewski, Xiaotian Zhu, Michael I Monteiro, Betty Chan, Fei Zhou, John W. Cuozzo, Diala Ezzeddine, Matthew A. Clark
المصدر: Cancer Research. 79:4453-4453
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Tumor microenvironment, Drug discovery, Chemistry, Purinergic receptor, Adenosine A2A receptor, Context (language use), Adenosine receptor, Adenosine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Cancer research, medicine, Receptor, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2dc1401d531967c3ca8a1ad1b2a794a2Test
https://doi.org/10.1158/1538-7445.am2019-4453Test -
10
المؤلفون: Shikha Ahlawat, Peter Juo, Jennifer R. Kowalski, Sandhya P. Koushika, Michael I. Monteiro, Emily Malkin
المصدر: Molecular Biology of the Cell
مصطلحات موضوعية: Nervous system, Green Fluorescent Proteins, Molecular Sequence Data, Kinesins, Nerve Tissue Proteins, Nervous System, Time-Lapse Imaging, Clathrin, Animals, Genetically Modified, 03 medical and health sciences, 0302 clinical medicine, Interneurons, medicine, Animals, Amino Acid Sequence, Receptors, AMPA, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Receptor, Molecular Biology, 030304 developmental biology, 0303 health sciences, Sequence Homology, Amino Acid, biology, fungi, Multivesicular Bodies, Glutamate receptor, Cyclin-Dependent Kinase 5, Articles, Cell Biology, biology.organism_classification, Endocytosis, Cell biology, Protein Transport, medicine.anatomical_structure, Microscopy, Fluorescence, Membrane Trafficking, Ventral nerve cord, Mutation, Synapses, biology.protein, Kinesin, Ap180, Lysosomes, 030217 neurology & neurosurgery, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42dbfb60a7b6c721d43d08909521de71Test
https://doi.org/10.1091/mbc.e12-04-0334Test