The prognostic effect of lymph node dissection in secondary lung tumor metastasectomies
| العنوان: | The prognostic effect of lymph node dissection in secondary lung tumor metastasectomies |
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| المؤلفون: | Salih, Duman, Berk, Çimenoğlu, Melike, Ülker, Melek, Ağkoç, Suat, Erus, Berker, Özkan, Murat, Kara, Alper, Toker |
| المصدر: | Turkish Journal of Thoracic and Cardiovascular Surgery. 30:235-240 |
| بيانات النشر: | Baycinar Tibbi Yayincilik, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Pulmonary and Respiratory Medicine, Surgery, Cardiology and Cardiovascular Medicine |
| الوصف: | Background: In this study, we aimed to investigate the prognostic effect of lymph node dissection in secondary lung tumor metastasectomies. Methods: Between January 2001 and December 2015, a total of 201 patients (122 males, 79 females; mean age: of 41.4±19.2 years; range, 3 to 79 years) who had pulmonary metastasectomy due to colorectal carcinoma, renal cell carcinoma, and soft tissue - skeletal sarcomas were retrospectively analyzed. The clinicopathological features of the patients, overall survival, and complication rates according to the presence of lymph node dissection were evaluated. Results: The most common histopathological subtype was a sarcoma in 118 (58.7%) patients, followed by colorectal carcinoma in 63 (31.3%) patients, and renal cell carcinoma in 20 (10%) patients. A total of 88 (43.7%) patients underwent systematic lymph node dissection with pulmonary metastasectomy. The mean overall survival of patients with and without lymph node dissection were 49±5.9 (95% confidence interval 37.3-60.6) and 26±4.4 (95% confidence interval 17.2-34.7) months, respectively (p=0.003). The five-year survival rates in colorectal carcinoma, renal cell carcinoma, and sarcoma were 52%, 30%, and 23%, respectively (p=0.002). Locoregional recurrences occurred in 15 (35.7%) patients in the lymph node dissection group and in 23 (60.5%) patients in the non-lymph node dissection group (p=0.026). Lymph node dissection did not show a significant relationship regarding to postoperative complications (p=0.09). Conclusion: Lymph node dissection following pulmonary metastasectomy may improve the overall survival and reduce locoregional recurrence, without any increase in morbidity and mortality. |
| تدمد: | 2149-8156 1301-5680 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a995de55f028a443f9bef7fc49ec8de5Test https://doi.org/10.5606/tgkdc.dergisi.2022.21402Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a995de55f028a443f9bef7fc49ec8de5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21498156 13015680 |
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