دورية أكاديمية
To compare the HOMA-IR and metabolic profile in lean and obese subjects with non-alcoholic fatty liver disease
العنوان: | To compare the HOMA-IR and metabolic profile in lean and obese subjects with non-alcoholic fatty liver disease |
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المؤلفون: | Meenu C. Nair, Lanord Stanley, Gisha Sivan, Janardanan Subramonia Kumar |
المصدر: | Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-6 (2024) |
بيانات النشر: | SpringerOpen, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Surgery LCC:Diseases of the digestive system. Gastroenterology |
مصطلحات موضوعية: | NAFLD, HOMA-IR, Metabolic syndrome, Fatty liver, Insulin resistance, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869 |
الوصف: | Abstract Background and objective Non-alcoholic fatty liver disease (NAFLD) is primarily perceived as a condition prevalent among obese individuals. Its pathogenesis is closely intertwined with metabolic syndrome components. However, the association between insulin resistance and NAFLD in nonobese individuals remains ambiguous. Observational studies have scrutinized the prevalence of insulin resistance and metabolic syndrome in lean NAFLD patients. Materials and methods This is an observational study, and NAFLD screening was carried out among inpatient and outpatient attendees at SRM Medical College’s General Medicine Department. Out of 200 screened patients meeting inclusion and exclusion criteria, 80 were diagnosed with non-alcoholic fatty liver disease (NAFLD). The assessment of metabolic syndrome was performed using the NCEP-ATP III criteria, allowing for comparison between groups concerning insulin resistance and metabolic parameters. Results Among NAFLD patients, those in the obese age group exhibited a higher prevalence of hypertension (57.8%; p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2090-6226 |
العلاقة: | https://doaj.org/toc/2090-6226Test |
DOI: | 10.1186/s43066-024-00341-8 |
الوصول الحر: | https://doaj.org/article/8119af3f8c0c4f5a89d6acdb8704449dTest |
رقم الانضمام: | edsdoj.8119af3f8c0c4f5a89d6acdb8704449d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20906226 |
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DOI: | 10.1186/s43066-024-00341-8 |