المؤلفون: Jiaxin Hu, Xiulong Shen, Mahboubeh Kheirabadi, Matthew D. Streeter, Ziqing Qian, V. Vinod Mootha, David R. Corey

المصدر: ACS Omega, Vol 8, Iss 45, Pp 42797-42802 (2023)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2470-1343Test

الوصول الحر: https://doaj.org/article/ae6a382237fa4f6b910135a6aa95d4ceTest

المؤلفون: Jiaxin Hu, Xiulong Shen, Mahboubeh Kheirabadi, Matthew D. Streeter, Ziqing Qian, V. Vinod Mootha, David R. Corey

مصطلحات موضوعية: Biochemistry, Medicine, Developmental Biology, Plasma Physics, Virology, successful drug development, splicing defects associated, require diverse strategies, effective curative treatment, cug morpholinos conjugated, cug therapies, cug oligomers, vision loss, tcf4 <, morpholino domain, morpholino conjugates, many patients, major cause, corneal transplantation

العلاقة: https://figshare.com/articles/journal_contribution/Targeting_the_Expanded_i_TCF4_i_Fuchs_Endothelial_Corneal_Dystrophy_CUG_Repeat_with_Morpholino_Peptide_Conjugates/24492354Test

الإتاحة: https://doi.org/10.1021/acsomega.3c05634.s001Test
https://figshare.com/articles/journal_contribution/Targeting_the_Expanded_i_TCF4_i_Fuchs_Endothelial_Corneal_Dystrophy_CUG_Repeat_with_Morpholino_Peptide_Conjugates/24492354Test

المؤلفون: Edward A. deRamon, Venkata R. Sabbasani, Matthew D. Streeter, Yannan Liu, Timothy R. Newhouse, David M. McDonald, David A. Spiegel

المصدر: Journal of the American Chemical Society. 144:21843-21847

مصطلحات موضوعية: Colloid and Surface Chemistry, Humans, General Chemistry, Protein Processing, Post-Translational, Biochemistry, Catalysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698ee075774f44323d7a3b9712808c31Test
https://doi.org/10.1021/jacs.2c09626Test

المؤلفون: David M McDonald, Sheldon Rowan, Matthew D. Streeter, David Spiegel, Allen Taylor, Jonathan Volkin, Jonathan Clark, Jason Ray

المصدر: ACS Chemical Biology. 15:2655-2661

مصطلحات موضوعية: Glycation End Products, Advanced, 0301 basic medicine, Aging, Immunogen, 01 natural sciences, Biochemistry, Antibodies, Retina, Lipofuscin, 03 medical and health sciences, chemistry.chemical_compound, Glycation, medicine, Animals, Pigment Epithelium of Eye, Retinal pigment epithelium, biology, 010405 organic chemistry, business.industry, General Medicine, Macular degeneration, medicine.disease, Immunohistochemistry, 0104 chemical sciences, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, chemistry, Polyclonal antibodies, biology.protein, Molecular Medicine, Female, Bruch Membrane, Rabbits, sense organs, Glucosepane, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286bf00c9139f6637aa5909847c88f81Test
https://doi.org/10.1021/acschembio.0c00093Test

المؤلفون: Jonathan Clark, David Spiegel, Matthew D. Streeter, Anne Segonds-Pichon, Izabella Niewczas, Irina M. Ivanova, Melanie Stammers

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, collagen, Tail, medicine.medical_specialty, Aging, Glycosylation, tendon, Lysine, Connective tissue, Glycobiology and Extracellular Matrices, cross-links, chemistry, Biochemistry, Mouse Tendon, Tendons, 03 medical and health sciences, Mice, protein cross-linking, Glycation, Diabetes mellitus, Internal medicine, Age related, medicine, Animals, Molecular Biology, connective tissue, lysine glycation, 030102 biochemistry & molecular biology, diabetes, Chemistry, Structural protein, mechanical stress, Cell Biology, medicine.disease, musculoskeletal system, Tendon, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, physical strain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9150e62a13b0a850a5145b8b95ad1ecTest
http://europepmc.org/articles/PMC7397091Test

المؤلفون: David Spiegel, Carlos Moreira-Neto, Sheldon Rowan, Naila Rabbani, Nadia K Waheed, Min-Lee Chang, Shuhong Jiang, Christa Cassalman, Kelsey Smith, Jonathan Volkin, Allen Taylor, Donald Smith, Matthew D. Streeter, Paul J. Thornalley

المصدر: Free Radic Biol Med

مصطلحات موضوعية: Glycation End Products, Advanced, 0301 basic medicine, medicine.medical_specialty, genetic structures, NF-E2-Related Factor 2, Retinal Pigment Epithelium, Biochemistry, Article, Macular Degeneration, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Atrophy, Physiology (medical), Internal medicine, Glycemic index, medicine, Animals, Glycemic, Advanced glycation end-product, Retinal pigment epithelium, business.industry, Macular degeneration, medicine.disease, eye diseases, NFE2L2, Diet, Mice, Inbred C57BL, Low-glycemic diet, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, chemistry, Geographic atrophy, Retinal pigmented epithelium, sense organs, Antioxidant, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190748834d867c1d6f4e2c2ea8a90044Test
https://doi.org/10.1016/j.freeradbiomed.2020.02.010Test

المؤلفون: David Spiegel, Kung‐Pern Wang, Venkata R. Sabbasani, Matthew D. Streeter

المصدر: Angewandte Chemie (International Ed. in English)

مصطلحات موضوعية: Ketone, General method, cyclization, One-Step, Sigmatropic reaction, 010402 general chemistry, 01 natural sciences, Catalysis, chemistry.chemical_compound, Rapid access, diaminoimidazoles, total synthesis, chemistry.chemical_classification, 010405 organic chemistry, Communication, advanced glycation end products, Methylglyoxal, sigmatropic rearrangement, Total synthesis, General Chemistry, General Medicine, Combinatorial chemistry, Tautomer, Communications, 0104 chemical sciences, chemistry, Synthetic Methods

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444e928a2edf1cf57f6fd2b4a804c73cTest
https://doi.org/10.1002/ange.201911156Test

المؤلفون: Kristie L. Rose, Philip J. Kingsley, David Spiegel, Matthew D. Streeter, Lawrence J. Marnett, Orrette R. Wauchope, Tina Wang, Michelle M. Mitchener, James A. Wepy, James J. Galligan, William N. Beavers

المصدر: Proceedings of the National Academy of Sciences. 115:9228-9233

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Arginine, 010402 general chemistry, 01 natural sciences, Histones, 03 medical and health sciences, chemistry.chemical_compound, Transcription (biology), Gene expression, Humans, Nucleosome, Multidisciplinary, biology, Methylglyoxal, Lactoylglutathione Lyase, Pyruvaldehyde, 0104 chemical sciences, Chromatin, Cell biology, HEK293 Cells, 030104 developmental biology, Histone, chemistry, Acetylation, biology.protein, Protein Processing, Post-Translational, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bfd369a71f4838f3ac570f1a83f078Test
https://doi.org/10.1073/pnas.1802901115Test

المؤلفون: Sainitin Donakonda, Bettina Lorenz-Depiereux, Thomas Misgeld, Andreas Dunkel, Sabine Schmitt, Corinna Dawid, Tina Wang, Kilian Eyerich, Vibor Laketa, Thomas Korn, Kerstin Lohr, David Spiegel, Christian Schmid, Matthew D. Streeter, Percy A. Knolle, Stefanie Eyerich, Luca Simeoni, Norbert Hüser, Annkristin Heine, Caroline Fecher, Jan E. Heil, Michael Hiltensperger, Nina Körber, Daniel Hartmann, Farhah Assaad, Tanja Bauer, Mathias Heikenwalder, Uwe Ahting, Martina Anton, Burkhart Schraven, Hans Zischka, Bastian Höchst, Melanie Laschinger, Thomas Hofmann, Peter J. Murray, Tobias Baumann, Johann Schredelseker

المصدر: Nature Immunology
Nat. Immunol. 21, 555-566 (2020)
Nature immunology 21(5), 555-566 (2020). doi:10.1038/s41590-020-0666-9

مصطلحات موضوعية: 0301 basic medicine, methods [Immunotherapy], Myeloid, T cell, medicine.medical_treatment, Immunology, Programmed Cell Death 1 Receptor, Melanoma, Experimental, metabolism [Programmed Cell Death 1 Receptor], Mice, Transgenic, Cell Communication, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Immune tolerance, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Immune system, medicine, Immune Tolerance, Immunology and Allergy, Animals, Humans, ddc:610, Melanoma, Cell Proliferation, Cell growth, immunology [Melanoma], Myeloid-Derived Suppressor Cells, immunology [CD8-Positive T-Lymphocytes], Methylglyoxal, immunology [Myeloid-Derived Suppressor Cells], Immunotherapy, Neoplasms, Experimental, Pyruvaldehyde, metabolism [Amine Oxidase (Copper-Containing)], 3. Good health, 030104 developmental biology, medicine.anatomical_structure, chemistry, Cancer research, Amine Oxidase (Copper-Containing), transplantation [CD8-Positive T-Lymphocytes], metabolism [Pyruvaldehyde], CD8, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285843f2a01b3cd8bb3ddcdc2a79ee6bTest

المؤلفون: Mogens Johannsen, Taoda Shi, Eli Chapman, James J. Galligan, James R. Roede, Dominique O. Gaffney, Colin C. Anderson, Erin Q. Jennings, Matthew D. Streeter, John O. Marentette, Anne-Mette Schou Oxvig, David Spiegel

المصدر: The FASEB Journal. 34:1-1

مصطلحات موضوعية: Glycolytic enzymes, Biochemistry, Non enzymatic, Chemistry, Lysine, Genetics, Molecular Biology, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::dcfbef377061d0aec516c6ced8a8b113Test
https://doi.org/10.1096/fasebj.2020.34.s1.02010Test