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1دورية أكاديمية
المؤلفون: M. Dominic Ryan (1677214), Alastair L. Parkes (11485035), David Corbett (324987), Anthony P. Dickie (2882588), Michelle Southey (11485038), Ole A. Andersen (2114842), Daniel B. Stein (1600624), Olivier R. Barbeau (2241841), Angelo Sanzone (2001946), Pia Thommes (1833613), John Barker (1677223), Ricky Cain (1300071), Christel Compper (527263), Magali Dejob (11485041), Alain Dorali (11485044), Donnya Etheridge (11485047), Sian Evans (7150334), Adele Faulkner (1359855), Elise Gadouleau (9187663), Timothy Gorman (11485050), Denes Haase (11485053), Maisie Holbrow-Wilshaw (11485056), Thomas Krulle (9187684), Xianfu Li (11485059), Christopher Lumley (7166261), Barbara Mertins (125533), Spencer Napier (2126395), Rajesh Odedra (1951660), Kostas Papadopoulos (9579014), Vasileios Roumpelakis (11485062), Kate Spear (11485065), Emily Trimby (11485068), Jennifer Williams (14164), Michael Zahn (2062351), Anthony D. Keefe (3622769), Ying Zhang (40767), Holly T. Soutter (11485071), Paolo A. Centrella (1463083), Matthew A. Clark (1370337), John W. Cuozzo (1665235), Christoph E. Dumelin (1272561), Boer Deng (9964680), Avery Hunt (11485074), Eric A. Sigel (3622766), Dawn M. Troast (2197303), Boudewijn L. M. DeJonge (11485077)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Pharmacology, Cancer, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, mouse infection models, maximal inhibitory concentration, encoded compound library, >‑ acetylglucosamine acyltransferase, >- acetylglucosamine acyltransferase, novel udp ‑<, 50 sub, escherichia coli lpxa, pseudomonas aeruginosa lpxa, udp -<, pseudomonas aeruginosa, n <, aeruginosa lpxa, study describes, selective inhibitor, resistant isolates, ray crystallography, original hit, novel series
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2دورية أكاديمية
المؤلفون: M. Dominic Ryan (1677214), Alastair L. Parkes (11485035), David Corbett (324987), Anthony P. Dickie (2882588), Michelle Southey (11485038), Ole A. Andersen (2114842), Daniel B. Stein (1600624), Olivier R. Barbeau (2241841), Angelo Sanzone (2001946), Pia Thommes (1833613), John Barker (1677223), Ricky Cain (1300071), Christel Compper (527263), Magali Dejob (11485041), Alain Dorali (11485044), Donnya Etheridge (11485047), Sian Evans (7150334), Adele Faulkner (1359855), Elise Gadouleau (9187663), Timothy Gorman (11485050), Denes Haase (11485053), Maisie Holbrow-Wilshaw (11485056), Thomas Krulle (9187684), Xianfu Li (11485059), Christopher Lumley (7166261), Barbara Mertins (125533), Spencer Napier (2126395), Rajesh Odedra (1951660), Kostas Papadopoulos (9579014), Vasileios Roumpelakis (11485062), Kate Spear (11485065), Emily Trimby (11485068), Jennifer Williams (14164), Michael Zahn (2062351), Anthony D. Keefe (3622769), Ying Zhang (40767), Holly T. Soutter (11485071), Paolo A. Centrella (1463083), Matthew A. Clark (1370337), John W. Cuozzo (1665235), Christoph E. Dumelin (1272561), Boer Deng (9964680), Avery Hunt (11485074), Eric A. Sigel (3622766), Dawn M. Troast (2197303), Boudewijn L. M. DeJonge (11485077)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Pharmacology, Cancer, Science Policy, Infectious Diseases, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, mouse infection models, maximal inhibitory concentration, encoded compound library, >‑ acetylglucosamine acyltransferase, >- acetylglucosamine acyltransferase, novel udp ‑<, 50 sub, escherichia coli lpxa, pseudomonas aeruginosa lpxa, udp -<, pseudomonas aeruginosa, n <, aeruginosa lpxa, study describes, selective inhibitor, resistant isolates, ray crystallography, original hit, novel series
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3دورية أكاديمية
المؤلفون: Esther C. Y. Lee (10586857), Andrew J. McRiner (2512648), Katy E. Georgiadis (10756246), Julie Liu (6557627), Zooey Wang (10756249), Andrew D. Ferguson (1427719), Benjamin Levin (10185539), Moritz von Rechenberg (10586875), Christopher D. Hupp (2377594), Michael I. Monteiro (10586860), Anthony D. Keefe (3622769), Allison Olszewski (2671783), Charles J. Eyermann (1667878), Paolo Centrella (10756252), Yanbin Liu (231378), Shilpi Arora (130546), John W. Cuozzo (1665235), Ying Zhang (40767), Matthew A. Clark (1370337), Christelle Huguet (8932838), Anna Kohlmann (1417150)
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Ecology, Inorganic Chemistry, Hematology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, DNA-Encoded Chemical Library Screen., SAR, carboxylic acid-containing compounds, hydroxy acid oxidase 1, DNA-Encoded Chemical Library, PK, PH, novel chemical series, non-acid-containing HAO 1 inhibitors, HAO 1 inhibitors, Compound 5, potency, AGXT, exploration, DECL, ADME, Structure-based drug design
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4دورية أكاديمية
المؤلفون: Jeremy S. Disch (1960423), Jennifer M. Duffy (10586854), Esther C. Y. Lee (10586857), Diana Gikunju (8932826), Betty Chan (1342416), Benjamin Levin (10185539), Michael I. Monteiro (10586860), Sarah A. Talcott (10586863), Anthony C. Lau (10586866), Fei Zhou (86034), Anton Kozhushnyan (10586869), Neil E. Westlund (10586872), Patrick B. Mullins (1601887), Yan Yu (56143), Moritz von Rechenberg (10586875), Junyi Zhang (290426), Yelena A. Arnautova (2710522), Yanbin Liu (231378), Ying Zhang (40767), Andrew J. McRiner (2512648), Anthony D. Keefe (3622769), Anna Kohlmann (1417150), Matthew A. Clark (1370337), John W. Cuozzo (1665235), Christelle Huguet (8932838), Shilpi Arora (130546)
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Cancer, Plant Biology, Chemical Sciences not elsewhere classified, Click chemistry synthesis, Bispecific Estrogen Receptor α Degr., novel PROTAC binding features, screening, ER α, breast cancer, ER α WT, novel bispecific degrader, bispecific nanomolar degraders, nanomolar ER α binding, alkyne E 3 ligase engagers panel, MCF 7 tumor growth, DNA-encoded chemical library, molecule exemplar 7, DECL, DNA-Encoded Chemical Library Screen., mouse xenograft model, GOF
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5دورية أكاديمية
المؤلفون: J. Willem M. Nissink (7424531), Sana Bazzaz (8932829), Carolyn Blackett (10270205), Matthew A. Clark (1370337), Olga Collingwood (10270208), Jeremy S. Disch (1960423), Diana Gikunju (8932826), Kristin Goldberg (1720258), John P. Guilinger (8932835), Elizabeth Hardaker (6158861), Edward J. Hennessy (1533484), Rachael Jetson (10270211), Anthony D. Keefe (3622769), William McCoull (1763365), Lindsay McMurray (2068162), Allison Olszewski (2671783), Ross Overman (1637866), Alexander Pflug (2885099), Marian Preston (3715579), Philip B. Rawlins (3622793), Emma Rivers (9015803), Marianne Schimpl (208250), Paul Smith (175833), Caroline Truman (112220), Elizabeth Underwood (9210380), Juli Warwicker (10270214), Jon Winter-Holt (8775911), Simon Woodcock (3682174), Ying Zhang (40767)
مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, lead-generation campaign, HT, selectivity profiles, data mining, kinase binding, cancer progression, orthogonal high-throughput screenin., DNA-encoded chemical library, campaign strategy, Concurrent execution, DECL screening, Mer inhibitors, screening outcomes, Comprehensive Lead-Generation Strat., kinase family, drug resistance, tumor microenvironment, TAM family members
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6
المؤلفون: Esther C. Y. Lee (10586857), Andrew J. McRiner (2512648), Katy E. Georgiadis (10756246), Julie Liu (6557627), Zooey Wang (10756249), Andrew D. Ferguson (1427719), Benjamin Levin (10185539), Moritz von Rechenberg (10586875), Christopher D. Hupp (2377594), Michael I. Monteiro (10586860), Anthony D. Keefe (3622769), Allison Olszewski (2671783), Charles J. Eyermann (1667878), Paolo Centrella (10756252), Yanbin Liu (231378), Shilpi Arora (130546), John W. Cuozzo (1665235), Ying Zhang (40767), Matthew A. Clark (1370337), Christelle Huguet (8932838), Anna Kohlmann (1417150)
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Ecology, Inorganic Chemistry, Hematology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, DNA-Encoded Chemical Library Screen., SAR, carboxylic acid-containing compounds, hydroxy acid oxidase 1, DNA-Encoded Chemical Library, PK, PH, novel chemical series, non-acid-containing HAO 1 inhibitors, HAO 1 inhibitors, Compound 5, potency, AGXT, exploration, DECL, ADME, Structure-based drug design
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7
المؤلفون: Esther C. Y. Lee (10586857), Andrew J. McRiner (2512648), Katy E. Georgiadis (10756246), Julie Liu (6557627), Zooey Wang (10756249), Andrew D. Ferguson (1427719), Benjamin Levin (10185539), Moritz von Rechenberg (10586875), Christopher D. Hupp (2377594), Michael I. Monteiro (10586860), Anthony D. Keefe (3622769), Allison Olszewski (2671783), Charles J. Eyermann (1667878), Paolo Centrella (10756252), Yanbin Liu (231378), Shilpi Arora (130546), John W. Cuozzo (1665235), Ying Zhang (40767), Matthew A. Clark (1370337), Christelle Huguet (8932838), Anna Kohlmann (1417150)
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Ecology, Inorganic Chemistry, Hematology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, DNA-Encoded Chemical Library Screen., SAR, carboxylic acid-containing compounds, hydroxy acid oxidase 1, DNA-Encoded Chemical Library, PK, PH, novel chemical series, non-acid-containing HAO 1 inhibitors, HAO 1 inhibitors, Compound 5, potency, AGXT, exploration, DECL, ADME, Structure-based drug design
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8
المؤلفون: Jeremy S. Disch (1960423), Jennifer M. Duffy (10586854), Esther C. Y. Lee (10586857), Diana Gikunju (8932826), Betty Chan (1342416), Benjamin Levin (10185539), Michael I. Monteiro (10586860), Sarah A. Talcott (10586863), Anthony C. Lau (10586866), Fei Zhou (86034), Anton Kozhushnyan (10586869), Neil E. Westlund (10586872), Patrick B. Mullins (1601887), Yan Yu (56143), Moritz von Rechenberg (10586875), Junyi Zhang (290426), Yelena A. Arnautova (2710522), Yanbin Liu (231378), Ying Zhang (40767), Andrew J. McRiner (2512648), Anthony D. Keefe (3622769), Anna Kohlmann (1417150), Matthew A. Clark (1370337), John W. Cuozzo (1665235), Christelle Huguet (8932838), Shilpi Arora (130546)
مصطلحات موضوعية: Biochemistry, Cell Biology, Pharmacology, Cancer, Plant Biology, Chemical Sciences not elsewhere classified, Click chemistry synthesis, Bispecific Estrogen Receptor α Degr., novel PROTAC binding features, screening, ER α, breast cancer, ER α WT, novel bispecific degrader, bispecific nanomolar degraders, nanomolar ER α binding, alkyne E 3 ligase engagers panel, MCF 7 tumor growth, DNA-encoded chemical library, molecule exemplar 7, DECL, DNA-Encoded Chemical Library Screen., mouse xenograft model, GOF
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9
المؤلفون: J. Willem M. Nissink (7424531), Sana Bazzaz (8932829), Carolyn Blackett (10270205), Matthew A. Clark (1370337), Olga Collingwood (10270208), Jeremy S. Disch (1960423), Diana Gikunju (8932826), Kristin Goldberg (1720258), John P. Guilinger (8932835), Elizabeth Hardaker (6158861), Edward J. Hennessy (1533484), Rachael Jetson (10270211), Anthony D. Keefe (3622769), William McCoull (1763365), Lindsay McMurray (2068162), Allison Olszewski (2671783), Ross Overman (1637866), Alexander Pflug (2885099), Marian Preston (3715579), Philip B. Rawlins (3622793), Emma Rivers (9015803), Marianne Schimpl (208250), Paul Smith (175833), Caroline Truman (112220), Elizabeth Underwood (9210380), Juli Warwicker (10270214), Jon Winter-Holt (8775911), Simon Woodcock (3682174), Ying Zhang (40767)
مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, lead-generation campaign, HT, selectivity profiles, data mining, kinase binding, cancer progression, orthogonal high-throughput screenin., DNA-encoded chemical library, campaign strategy, Concurrent execution, DECL screening, Mer inhibitors, screening outcomes, Comprehensive Lead-Generation Strat., kinase family, drug resistance, tumor microenvironment, TAM family members