المؤلفون: Mathy, Christopher J P, Mishra, Parul, Flynn, Julia M, Perica, Tina, Mavor, David, Bolon, Daniel N A, Kortemme, Tanja

المصدر: Mathy, Christopher J P; Mishra, Parul; Flynn, Julia M; Perica, Tina; Mavor, David; Bolon, Daniel N A; Kortemme, Tanja (2023). A complete allosteric map of a GTPase switch in its native cellular network. Cell Systems, 14(3):237-246.e7.

مصطلحات موضوعية: Department of Biochemistry, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: application/pdf

العلاقة: https://www.zora.uzh.ch/id/eprint/231814/1/1_s2.0_S2405471223000297_main.pdfTest; info:pmid/36801015; urn:issn:2405-4712

الإتاحة: https://doi.org/10.5167/uzh-23181410.1016Test/j.cels.2023.01.003
https://www.zora.uzh.ch/id/eprint/231814Test/
https://www.zora.uzh.ch/id/eprint/231814/1/1_s2.0_S2405471223000297_main.pdfTest

المؤلفون: Perica, Tina, Mathy, Christopher J. P., Xu, Jiewei, Jang, Gwendolyn M., Zhang, Yang, Kaake, Robyn, Ollikainen, Noah, Braberg, Hannes, Swaney, Danielle L., Lambright, David G., Kelly, Mark J. S., Krogan, Nevan J., Kortemme, Tanja

المساهمون: Department of Biochemistry and Molecular Pharmacology, Program in Molecular Medicine

المصدر: bioRxiv

مصطلحات موضوعية: Ran, Gsp1, GTPase, molecular switches, systems biology, thermodynamic coupling, Amino Acids, Peptides, and Proteins, Biophysics, Molecular Biology

العلاقة: Now published in Nature doi:10.1038/s41586-021-03982-6; bioRxiv 2020.01.04.893909; doi: https://doi.org/10.1101/2020.01.04.893909Test. Link to preprint on bioRxiv.; http://hdl.handle.net/20.500.14038/29808Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=3036&context=faculty_pubs&unstamped=1Test; https://escholarship.umassmed.edu/faculty_pubs/2017Test; faculty_pubs/2017

الإتاحة: https://doi.org/10.1101/2020.01.04.893909Test
https://doi.org/20.500.14038/29808Test
https://doi.org/10.1038/s41586-021-03982-6Test
https://hdl.handle.net/20.500.14038/29808Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=3036&context=faculty_pubs&unstamped=1Test
https://escholarship.umassmed.edu/faculty_pubs/2017Test

المؤلفون: Baker, Jordan J., Mathy, Christopher J. P., Schaletzky, Julia

المساهمون: Papin, Jason A., Eric and Wendy Schmidt, Fast Grants

المصدر: PLOS Computational Biology ; volume 17, issue 12, page e1009624 ; ISSN 1553-7358

الإتاحة: https://doi.org/10.1371/journal.pcbi.1009624Test

المؤلفون: Perica, Tina, Mathy, Christopher J P, Xu, Jiewei, Jang, Gwendolyn Μ, Zhang, Yang, Kaake, Robyn, Ollikainen, Noah, Braberg, Hannes, Swaney, Danielle L, Lambright, David G, Kelly, Mark J S, Krogan, Nevan J, Kortemme, Tanja

المساهمون: Biochemistry and Molecular Biotechnology, Program in Molecular Medicine

المصدر: Nature ; 599 ; 7883 ; 152 ; 157 ; United States ; United Kingdom ; England

مصطلحات موضوعية: GTP-binding protein regulators, Molecular conformation, Networks and systems biology, Proteomic analysis, Regulatory networks

العلاقة: Nature; https://doi.org/10.1038/s41586-021-03982-6Test; Perica T, Mathy CJP, Xu J, Jang GΜ, Zhang Y, Kaake R, Ollikainen N, Braberg H, Swaney DL, Lambright DG, Kelly MJS, Krogan NJ, Kortemme T. Systems-level effects of allosteric perturbations to a model molecular switch. Nature. 2021 Nov;599(7883):152-157. doi:10.1038/s41586-021-03982-6. Epub 2021 Oct 13. PMID: 34646016; PMCID: PMC8571063.; http://hdl.handle.net/20.500.14038/51671Test

الإتاحة: https://doi.org/10.1038/s41586-021-03982-6Test
https://doi.org/20.500.14038/51671Test
https://hdl.handle.net/20.500.14038/51671Test

المؤلفون: Perica, Tina, Mathy, Christopher J P, Xu, Jiewei, Jang, Gwendolyn Μ, Zhang, Yang, Kaake, Robyn, Ollikainen, Noah, Braberg, Hannes, Swaney, Danielle L, Lambright, David G, Kelly, Mark J S, Krogan, Nevan J, Kortemme, Tanja

المساهمون: University of Zurich, Krogan, Nevan J, Kortemme, Tanja

المصدر: Nature, vol 599, iss 7883

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, General Science & Technology, 1.1 Normal biological development and functioning, 610 Medicine & health, Bioengineering, Saccharomyces cerevisiae, Allosteric Regulation, Underpinning research, Catalytic Domain, 10019 Department of Biochemistry, Genetics, Guanine Nucleotide Exchange Factors, Point Mutation, 2.1 Biological and endogenous factors, Aetiology, Monomeric GTP-Binding Proteins, 1000 Multidisciplinary, Binding Sites, GTPase-Activating Proteins, Nuclear Proteins, Kinetics, 570 Life sciences, biology, HIV/AIDS, Guanosine Triphosphate, Generic health relevance, Protein Binding

وصف الملف: Perica_et_al._2021.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cc616544d6f27bcc29effbbaf466f76bTest
https://escholarship.org/uc/item/3zb6775vTest

المؤلفون: Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Hüttenhain, Ruth, Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J., Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J. P., Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J., Saltzberg, Daniel J., Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B., Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J., O’Neal, Michael C., Cai, Yiming, Chang, Jason C. J., Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Wenzell, Nicole A., Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M., Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Rosenberg, Oren S., Verba, Kliment A., Agard, David A., Ott, Melanie, Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, d’Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S., Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Sali, Andrej, Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Kortemme, Tanja, Beltrao, Pedro, Vignuzzi, Marco, García-Sastre, Adolfo, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.

المصدر: Nature; July 2020, Vol. 583 Issue: 7816 p459-468, 10p