التفاصيل البيبلوغرافية
| العنوان: |
INTEGRATING GENETIC AND CLINICAL DATA INTO A DECISION SUPPORT SYSTEM FOR COLON CANCER DIAGNOSIS |
| المؤلفون: |
Nikolaos Giannakeas, Themis P. Exarchos, Yorgos Goletsis, Costas Papaloukas, Dimitrios I. Fotiadis, Babak Akhgar, Massimo Gulissano |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
http://www.medlab-uoi.gr/cv_pdf/giannakeas/Integrating+Genetic+And+Clinical+Data+Into+A+Decision+Support+System+For+Colon+Cancer+Diagnosis.pdfTest. |
| المجموعة: |
CiteSeerX |
| الوصف: |
In the cancer treatment domain, accuracy in patient staging and in the selection of personalised treatment plan can be of critical importance for patient’s health or even survival. A Decision Support Platform that can correlate the patient clinical situation with the patient DNA Single Nucleotide Polymorphisms (SNPs) / mutations and so with his/her real condition can provide the oncologist with a better understanding of the personalized conditions of every single patient. In this paper we present the MATCH system which performs data integration between medicine and molecular biology, by developing a framework where, clinical and genomic features are appropriately combined in order to handle colon cancer diseases. Clustering (profiling) algorithms are designed and developed in order to analyze these heterogeneous data and extract useful information and knowledge. The constitution of such a decision support system is based on a) colon cancer clinical data and b) biological information that is derived from genomic sources. Through this integration, real time conclusions can be drawn for early diagnosis, staging and more effective colon cancer treatment. MATCH uses information directly from the DNA sequence of a patient in different stages of the cancer. Intelligent components are designed and developed which can identify single nucleotide polymorphisms (SNPs) |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.689.3880Test; http://www.medlab-uoi.gr/cv_pdf/giannakeas/Integrating+Genetic+And+Clinical+Data+Into+A+Decision+Support+System+For+Colon+Cancer+Diagnosis.pdfTest |
| الإتاحة: |
http://www.medlab-uoi.gr/cv_pdf/giannakeas/Integrating+Genetic+And+Clinical+Data+Into+A+Decision+Support+System+For+Colon+Cancer+Diagnosis.pdfTest |
| حقوق: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.A9B48A90 |
| قاعدة البيانات: |
BASE |
