دورية أكاديمية
A clinical outcome-based prospective study on venous thromboembolism after cancer surgery: The @RISTOS Project
| العنوان: | A clinical outcome-based prospective study on venous thromboembolism after cancer surgery: The @RISTOS Project |
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| المؤلفون: | Agnelli, Giancarlo, Bolis, Giorgio, Capussotti, Lorenzo, Scarpa, Roberto Mario, Tonelli, Francesco, Bonizzoni, Erminio, Moia, Marco, Parazzini, Fabio, Rossi, Romina, SONAGLIA, FRANCESCO, Valarani, Bettina, Bianchini, Carlo, Gussoni, Gualberto, Tonelli, F., Martinelli, I., Andreoni, B., Biffi, R., Cenciarelli, S., Calgaro, M., Polastri, R., Zorzi, D., Tubaro, A., Perna, R., Vicentini, C., Montemurro, S., Caliandro, C., Ruggeri, E., Gennari, L., Brocchi, A., Quagliuolo, V., Ragni, F., Conti, G., Cretarola, E., Pagliarulo, A., D'Achille, G., Bartoli, A., Bussotti, C., Ricci, E., Servoli, A., Carrieri, G., Corvasce, T., Disabato, G., Moretti, R., Bencini, L., Cantafio, S., Scatizzi, M., Scambia, G., Foti, E., Frigerio, L., Carlini, L., Gallo, A., Mirone, V., Mangiapia, F., Palmieri, A., Mazzaferro, V., Ravagnani, F., Romito, R., Ferrari, A., Mangili, G., Carnelli, P., VIGANO', RENATA MARIA, Dionigi, R., Castelli, P., Caronno, R., Piffaretti, G., Uccella, L., PARISI, VERONICA, Ruffolo, F., Verrusio, C., Tateo, S., Mereu, L., Salamano, S., Valanzano, R., Lise, M., Nitti, D., Belluco, C., Forlin, M., Massarut, R., Usai, E., De Lisa, A., Cirillo, P., Mosella, G., Quarto, G., Cappiello, A., Mosella, F., Pastore, M., Mangioni, C., Pellegrino, A., Villa, A., Daddi, G., Cagini, L., Calzolari, F., Nigro, R., Confuorto, G., Pecorelli, S., Odicino, F., Sacconi, T., Scollo, P., Scibilia, G., DEL GAUDIO, ANDREA, Accorsi, D., Fiaccavento, G., Plaino, F. |
| المساهمون: | Agnelli, Giancarlo, Bolis, Giorgio, Capussotti, Lorenzo, Scarpa, Roberto Mario, Tonelli, Francesco, Bonizzoni, Erminio, Moia, Marco, Parazzini, Fabio, Rossi, Romina, Sonaglia, Francesco, Valarani, Bettina, Bianchini, Carlo, Gussoni, Gualberto, Tonelli, F., Martinelli, I., Andreoni, B., Biffi, R., Cenciarelli, S., Calgaro, M., Polastri, R., Zorzi, D., Tubaro, A., Perna, R., Vicentini, C., Montemurro, S., Caliandro, C., Ruggeri, E., Gennari, L., Brocchi, A., Quagliuolo, V., Ragni, F., Conti, G., Cretarola, E., Pagliarulo, A., D'Achille, G., Bartoli, A., Bussotti, C., Ricci, E., Servoli, A., Carrieri, G., Corvasce, T., Disabato, G., Moretti, R., Bencini, L., Cantafio, S., Scatizzi, M., Scambia, G., Foti, E., Frigerio, L., Carlini, L., Gallo, A., Mirone, V., Mangiapia, F., Palmieri, A., Mazzaferro, V., Ravagnani, F., Romito, R., Ferrari, A., Mangili, G., Carnelli, P., Vigano', RENATA MARIA, Dionigi, R., Castelli, P., Caronno, R., Piffaretti, G., Uccella, L., Parisi, Veronica, Ruffolo, F., Verrusio, C., Tateo, S., Mereu, L., Salamano, S., Valanzano, R., Lise, M., Nitti, D., Belluco, C., Forlin, M., Massarut, R., Usai, E., De Lisa, A., Cirillo, P., Mosella, G., Quarto, G., Cappiello, A., Mosella, F., Pastore, M., Mangioni, C., Pellegrino, A., Villa, A., Daddi, G., Cagini, L., Calzolari, F., Nigro, R., Confuorto, G., Pecorelli, S., Odicino, F., Sacconi, T., Scollo, P., Scibilia, G., DEL GAUDIO, Andrea |
| سنة النشر: | 2006 |
| المجموعة: | IRIS Università degli Studi di Perugia |
| مصطلحات موضوعية: | Surgery |
| الوصف: | Background Data: The epidemiology of venous throinboembolism (VTE) after cancer surgery is based on clinical trials oil VTE prophylaxis that used venography to screen deep vein thrombosis (DVT). However, the clinical relevance of asymptomatic venography-detected DVT is unclear, and the population of these clinical trials is not necessarily representative of the overall cancer surgery population. Objective: The aim of this study was to evaluate the incidence of clinically overt VTE in a wide spectrum of consecutive patients undergoing surgery for cancer and to identify risk factors for VTE. Methods: @RISTOS was a prospective observational study in patients undergoing general, urologic, or gynecologic surgery. Patients were assessed for clinically overt VTE occurring up to 30 5 days after surgery or more if the hospital stay was longer than 35 days. All outcome events were evaluated by an independent Adjudication Committee. Results: A total of 2373 patients were included in the study: 1238 (52%) undergoing general, 685 (29%) urologic, and 450 (19%) gynecologic surgery. In-hospital prophylaxis was given in 81.6% and postdischarge prophylaxis in 30.7% of the patients. Fifty patients (2.1%) were adjudicated as affected by clinically overt VTE (DVT, 0.42%; nonfatal pulmonary embolism, 0.88%; death 0.80%). The incidence of VTE was 2.83% in general surgery, 2.0% in gynecologic surgery, and 0.87% in urologic Surgery. Forty percent of the events occurred later than 21 days from surgery. The overall death rate was 1.72%; in 46.3% of the cases, death was caused by VTE. In a multivariable analysis, 5 risk factors were identified: age above 60 years (2.63, 95% confidence interval, 1.21-5.71), previous VTE (5.98, 2.13-16.80), advanced cancer (2.68, 1.37-5.24), anesthesia lasting more than 2 hours (4.50, 1.06-19.04), and bed rest longer than 3 days (4.37, 2.45-7.78). Conclusions: VTE remains a common complication of cancer surgery, with a remarkable proportion of events occurring late after surgery. In patients undergoing ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000234311800014; volume:243; issue:1; firstpage:89; lastpage:95; numberofpages:7; journal:ANNALS OF SURGERY; http://hdl.handle.net/11391/1450111Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-30144440519 |
| DOI: | 10.1097/01.sla.0000193959.44677.48 |
| الإتاحة: | https://doi.org/10.1097/01.sla.0000193959.44677.48Test http://hdl.handle.net/11391/1450111Test |
| رقم الانضمام: | edsbas.EF15E417 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1097/01.sla.0000193959.44677.48 |
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