التفاصيل البيبلوغرافية
العنوان:
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types
المؤلفون:
Dirk S. Paul , Andrew E. Teschendorff , Mary A.N. Dang , Robert Lowe , Mohammed I. Hawa , Simone Ecker , Huriya Beyan , Stephanie Cunningham , Alexandra R. Fouts , Anita Ramelius , Frances Burden , Samantha Farrow , Sophia Rowlston , Karola Rehnstrom , Mattia Frontini , Kate Downes , Stephan Busche , Warren A. Cheung , Bing Ge , Marie-Michelle Simon , David Bujold , Tony Kwan , Guillaume Bourque , Avik Datta , Ernesto Lowy , Laura Clarke , Paul Flicek , Emanuele Libertini , Simon Heath , Marta Gut , Ivo G Gut , Willem H. Ouwehand , Tomi Pastinen , Nicole Soranzo , Sabine E. Hofer , Beate Karges , Thomas Meissner , Bernhard O. Boehm , Corrado Cilio , Helena Elding Larsson , Åke Lernmark , Andrea K. Steck , Vardhman K. Rakyan , Stephan Beck , R. David Leslie
المصدر:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
بيانات النشر:
Nature Portfolio, 2016.
سنة النشر:
2016
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
The incidence of type 1 diabetes is increasing, potentially implicating non-genetic factors. Here the authors conduct an epigenome-wide association study in disease-discordant twins and find increased DNA methylation variability at genes associated with immune cell metabolism and the cell cycle.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/ncomms13555
الوصول الحر:
https://doaj.org/article/74847440186d44ba8513e31e9862b708Test
رقم الانضمام:
edsdoj.74847440186d44ba8513e31e9862b708
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