المؤلفون: AndréR.A. Marques, Mina Mirzaian, Hisako Akiyama, Patrick Wisse, Maria J. Ferraz, Paulo Gaspar, Karen Ghauharali-van der Vlugt, Rianne Meijer, Pilar Giraldo, Pilar Alfonso, Pilar Irún, Maria Dahl, Stefan Karlsson, Elena V. Pavlova, Timothy M. Cox, Saskia Scheij, Marri Verhoek, Roelof Ottenhoff, CindyP.A.A. van Roomen, Navraj S. Pannu, Marco van Eijk, Nick Dekker, Rolf G. Boot, Herman S. Overkleeft, Edward Blommaart, Yoshio Hirabayashi, Johannes M. Aerts

المصدر: Journal of Lipid Research, Vol 57, Iss 3, Pp 451-463 (2016)

مصطلحات موضوعية: glucosyl-β-D-cholesterol, glucosylceramide, glucocerebrosidase, Gaucher disease, Niemann-Pick type C disease, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520354444Test; https://doaj.org/toc/0022-2275Test

الوصول الحر: https://doaj.org/article/57f08df9b338494281ce0b82ea7d752aTest

المؤلفون: Chi-Lin Kuo, Rolf G. Boot, Marta Artola, Qin Su, Lindsey T. Lelieveld, Marri Verhoek, Sybrin P. Schröder, Maria J. Ferraz, Herman S. Overkleeft, Johannes M. F. G. Aerts

المصدر: Chembiochem
Chembiochem, 22, 1-10. WILEY-V C H VERLAG GMBH

مصطلحات موضوعية: Molecular Conformation, Gaucher disease, Xylose, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, GBA3, activity-based probe, Animals, Humans, Glycoside hydrolase, Enzyme Inhibitors, Molecular Biology, Cells, Cultured, Zebrafish, 030304 developmental biology, 0303 health sciences, Full Paper, Chemistry, glucocerebrosidase, Organic Chemistry, Full Papers, Cyclohexanols, In vitro, 3. Good health, Cyclophellitol, HEK293 Cells, cyclophellitol, Molecular Medicine, Glucosylceramidase, Glucocerebrosidase, 030217 neurology & neurosurgery, Conduritol, conduritol B-epoxide

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051ee41c7214160b3f631d67d2be9f0eTest
http://europepmc.org/articles/PMC8596838Test

المؤلفون: Cindy P. A. A. van Roomen, Ewout Foppen, Mina Mirzaian, Sander Kooijman, Saskia Scheij, Herman S. Overkleeft, Chun-Xia Yi, Roelof Ottenhoff, Marco van Eijk, Clarita Mergen, Patrick C.N. Rensen, Yanan Wang, Kirstin Jansen, Daniela Herrera Moro Chao, Matthias H. Tschöp, Johannes M. F. G. Aerts, Edwin T. Parlevliet, Marri Verhoek, Dawei Wang, André Marques, Rolf G. Boot, Andries Kalsbeek, Randy J. Seeley

المساهمون: University of Zurich, Aerts, Johannes M F G, Netherlands Institute for Neuroscience (NIN), Laboratory for Endocrinology, Medical Biochemistry, ACS - Atherosclerosis & ischemic syndromes, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Amsterdam Gastroenterology Endocrinology Metabolism, Endocrinology, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Amsterdam Cardiovascular Sciences, APH - Aging & Later Life

المصدر: Diabetes, 68(12), 2223-2234. AMER DIABETES ASSOC
Diabetes 68, 2223-2234 (2019)
Diabetes, 68(12), 2223-2234
Diabetes, 68, 2223-2234. American Diabetes Association Inc.
Diabetes, 68(12), 2223-2234. American Diabetes Association Inc.

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, 1-Deoxynojirimycin, Endocrinology, Diabetes and Metabolism, Iminosugar, Adipose tissue, Adamantane, 610 Medicine & health, 030209 endocrinology & metabolism, Satiation, Carbohydrate metabolism, Mice, 03 medical and health sciences, Endocrinology, 0302 clinical medicine, Adipose Tissue, Brown, Glucagon-Like Peptide 1, 10183 Swiss Institute of Allergy and Asthma Research, Internal medicine, Brown adipose tissue, Internal Medicine, medicine, Animals, Glucose homeostasis, Secretion, Obesity, Rats, Wistar, Receptor, business.industry, Antagonist, Brain, Rats, Mice, Inbred C57BL, Diabetes and Metabolism, 2712 Endocrinology, Diabetes and Metabolism, Glucose, 030104 developmental biology, medicine.anatomical_structure, 2724 Internal Medicine, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6eeea7db358776e32d871b6706e3ba6Test
https://hdl.handle.net/1887/3199006Test

المؤلفون: Rolf G Boot, Marri Verhoek, Maaike De Fost, Carla E M Hollak, Mario Maas, Boris Bleijlevens, Marielle J, Van Breemen, Marjan Van Meurs, Leonie A Boven, Jon D Laman, Mary Teresa Moran, Timothy M Cox, Johannes M F G Aerts, Interleukins Articles, Rolf G. Boot, Carla E. M. Hollak, Marielle J. Van Breemen, Leonie A. Boven, Jon D. Laman, Timothy M. Cox, Johannes M. F. G. Aerts

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://bloodjournal.hematologylibrary.org/content/early/2003/09/11/blood-2003-05-1612.full.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.326.5580Test; http://bloodjournal.hematologylibrary.org/content/early/2003/09/11/blood-2003-05-1612.full.pdfTest

الإتاحة: http://bloodjournal.hematologylibrary.org/content/early/2003/09/11/blood-2003-05-1612.full.pdfTest

المؤلفون: Rolf G. Boot, Marri Verhoek, Maaike De Fost, Carla E. M. Hollak, Mario Maas, Boris Bleijlevens, Marielle J. Van Breemen, Marjan Van Meurs, Leonie A. Boven, Jon D. Laman, Mary Teresa Moran, Timothy M. Cox, Johannes M. F. G. Aerts, Interleukins Articles

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://bloodjournal.hematologylibrary.org/content/103/1/33.full.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.881Test; http://bloodjournal.hematologylibrary.org/content/103/1/33.full.pdfTest

الإتاحة: http://bloodjournal.hematologylibrary.org/content/103/1/33.full.pdfTest

المؤلفون: Shoichiro Ohta, Ulf Hammar, Cilla Söderhäll, Barbro Dahlén, Kenji Izuhara, Sven-Erik Dahlén, Maciej Kupczyk, Juha Kere, Anna James, Elisabeth H. Bel, Rolf G. Boot, Junya Ono, Lovisa E. Reinius, Marri Verhoek, Anna Gomes

المساهمون: Other departments, AII - Amsterdam institute for Infection and Immunity, Pulmonology

المصدر: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
American Journal of Respiratory and Critical Care Medicine, 193(2), 131-142. AMER THORACIC SOC
American journal of respiratory and critical care medicine, 193(2), 131-142. American Thoracic Society
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193(2), 131-142

مصطلحات موضوعية: Male, 0301 basic medicine, AIRWAY INFLAMMATION, Disease, Critical Care and Intensive Care Medicine, Severity of Illness Index, Pulmonary Disease, Chronic Obstructive, chitotriosidase, 0302 clinical medicine, Lectins, Multicenter Studies as Topic, Longitudinal Studies, Young adult, Chitinase-3-Like Protein 1, COPD, CHITINASE-LIKE PROTEIN, Smoking, GENETIC-VARIATION, Middle Aged, Europe, LUNG-FUNCTION, Hexosaminidases, ATOPIC ASTHMA, Disease Progression, Regression Analysis, Female, Steroids, Adult, Pulmonary and Respiratory Medicine, medicine.medical_specialty, YKL-40, Adolescent, MAMMALIAN CHITINASE, Adipokine, CHI3L1, chronic obstructive pulmonary disease, Young Adult, 03 medical and health sciences, Adipokines, Internal medicine, 3-LIKE 1, Severity of illness, medicine, Humans, ALLERGEN CHALLENGE, MATRIX PROTEIN, Aged, Asthma, Polymorphism, Genetic, business.industry, GLYCOSYL HYDROLASES, asthma, medicine.disease, respiratory tract diseases, 030104 developmental biology, 030228 respiratory system, Immunology, business, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fd11685d715b2e1a44c7d991a228aeTest
https://doi.org/10.1164/rccm.201504-0760ocTest

المؤلفون: Adrianus M. C. H. van den Nieuwendijk, Daniel Mink, Veronica Coco Rohde, Gijsbert A. van der Marel, Jianbing Jiang, Daniel W. Wright, Bogdan I. Florea, Johannes M. F. G. Aerts, Gideon J. Davies, Wouter W. Kallemeijn, Hans van den Elst, Wilma E. Donker-Koopman, Martin Schürmann, Nan Li, Rolf G. Boot, Saskia Scheij, Marri Verhoek, Jeroen D. C. Codée, Herman S. Overkleeft, Elisa Colomina Folch

المساهمون: Other departments, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences

المصدر: CHEMICAL SCIENCE, 6(5), 2782-2789. Royal Society of Chemistry
Chemical Science, 6(5), 2782-2789

مصطلحات موضوعية: biology, genetic structures, 010405 organic chemistry, Stereochemistry, Chemistry, Activity-based proteomics, Active site, Stereoisomerism, General Chemistry, 010402 general chemistry, medicine.disease, biology.organism_classification, 01 natural sciences, Fucosidosis, In vitro, 0104 chemical sciences, 3. Good health, Biochemistry, In vivo, Hydrolase, medicine, biology.protein, Bacteria

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c1b0655d1799327f935b9d7fee32e0Test
https://doi.org/10.1039/c4sc03739aTest

المؤلفون: Daniela Herrera Moro, Bogdan I. Florea, Timothy M. Cox, Olivier R. Martin, Marri Verhoek, Saskia Scheij, André R. A. Marques, Nee Na Kim, Wouter W. Kallemeijn, Rolf G. Boot, Jessica K. Nelson, Herman S. Overkleeft, Lianne I. Willems, Roelof Ottenhoff, Johannes M. F. G. Aerts, Cindy P. A. A. van Roomen, M. Begoña Cachón-González, Anna Biela-Banas

المساهمون: Medical Biochemistry, Graduate School, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Cardiovascular Sciences, ACS - Atherosclerosis & ischemic syndromes, ACS - Diabetes & metabolism

المصدر: Chembiochem, 18(4), 402-412. Wiley-VCH Verlag

مصطلحات موضوعية: 0301 basic medicine, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Biochemistry, 03 medical and health sciences, Galactosylceramidase, Hydrolase, medicine, Beta-galactosidase, Molecular Biology, chemistry.chemical_classification, Mutation, biology, Molecular Structure, Organic Chemistry, medicine.disease, 0104 chemical sciences, Leukodystrophy, Globoid Cell, Lysosomal Storage Diseases, 030104 developmental biology, Enzyme, chemistry, Molecular Probes, biology.protein, Krabbe disease, Molecular Medicine, Specific activity, Molecular probe, Deficiency Diseases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5408323f10bcb551113378d4c12edaaaTest
https://hdl.handle.net/1887/3199629Test

المؤلفون: Rolf G. Boot, Bogdan I. Florea, Jeroen D. C. Codée, Wilma E. Donker-Koopman, Benjamin Murray, Saskia Scheij, Wouter W. Kallemeijn, Marri Verhoek, Herman S. Overkleeft, Johannes M. F. G. Aerts, Thomas J. M. Beenakker, Gijsbert A. van der Marel, Lianne I. Willems, Maria J. Ferraz, Erwin R. van Rijssel

المساهمون: Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, Graduate School, Amsterdam Cardiovascular Sciences

المصدر: Journal of the American Chemical Society, 136(33), 11622-11625. American Chemical Society

مصطلحات موضوعية: Cell type, Aziridines, Endogeny, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, 03 medical and health sciences, Structure-Activity Relationship, Colloid and Surface Chemistry, α galactosidase, medicine, Structure–activity relationship, Humans, 030304 developmental biology, Fluorescent Dyes, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, General Chemistry, medicine.disease, Fabry disease, 0104 chemical sciences, 3. Good health, alpha-Galactosidase, Active enzyme

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1757c3ffcec39116e9bfc8ac48e3911Test
https://doi.org/10.1021/ja507040nTest

المؤلفون: Johannes M. F. G. Aerts, Marri Verhoek, Timothy M. Cox, Elena Pavlova, Wilma E. Donker-Koopman, Rolf G. Boot, Jessica K. Nelson, Gert Jan Kramer, Wouter W. Kallemeijn, Mary Teresa Moran, Wouter Wegdam, Roelof Ottenhoff, Jon D. Laman, Marco van Eijk, Paulo Gaspar, Tanit L. Gabriel, Johannes P. C. Vissers

المساهمون: Cox, Timothy [0000-0002-4951-9941], Pavlova, Elena [0000-0003-0187-5098], Apollo - University of Cambridge Repository, Molecular Neuroscience and Ageing Research (MOLAR), Translational Immunology Groningen (TRIGR), Other departments, Graduate School, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Medical Biochemistry, ACS - Amsterdam Cardiovascular Sciences, AII - Amsterdam institute for Infection and Immunity

المصدر: FEBS Open Bio
FEBS Open Bio, 6(9), 902-913. Wiley-Blackwell
FEBS Open Bio, 6(9), 902-913. Wiley Open Access
FEBS open bio, 6(9), 902-913. Wiley-Blackwell

مصطلحات موضوعية: 0301 basic medicine, DC-HIL, EXPRESSION, GLUCOCEREBROSIDASE, Pathology, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Genetic enhancement, Cell, DC‐HIL, Biology, storage disease, PHENOTYPE, osteoactivin, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chitotriosidase, Lysosome, glucosylceramide, medicine, CELL, Research Articles, GPNMB, PLASMA, CCL18, GENE-THERAPY, nutritional and metabolic diseases, FORMATION IN-VIVO, Phenotype, 3. Good health, MARKED ELEVATION, nervous system diseases, 030104 developmental biology, medicine.anatomical_structure, DIFFERENTIATION, lysosome, Biomarker (medicine), Glucocerebrosidase, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9904b801f366cbc06c3d1033778f123cTest
https://www.repository.cam.ac.uk/handle/1810/289591Test