Insulin requirement of simple and complex carbohydrate foods in type 1 (insulin-dependent) CSII-treated diabetic subjects, obtained by Biostator. Correlation with glycaemic index
| العنوان: | Insulin requirement of simple and complex carbohydrate foods in type 1 (insulin-dependent) CSII-treated diabetic subjects, obtained by Biostator. Correlation with glycaemic index |
|---|---|
| المؤلفون: | Gianfranco La Nave, Giuseppe Casalini, Fabio Capani, Ester Vitacolonna, Giuseppe Zappone, Agostino D’Emilio, Agostino Consoli, Mariarosa Loragno |
| المصدر: | Acta Diabetologica. 28:47-53 |
| بيانات النشر: | Springer Science and Business Media LLC, 1991. |
| سنة النشر: | 1991 |
| مصطلحات موضوعية: | Adult, Blood Glucose, medicine.medical_specialty, Sucrose, Endocrinology, Diabetes and Metabolism, Coefficient of variation, medicine.medical_treatment, chemistry.chemical_compound, Insulin Infusion Systems, Endocrinology, Animal science, Internal medicine, Diabetes mellitus, Diet, Diabetic, Dietary Carbohydrates, Internal Medicine, Humans, Medicine, Pancreatic hormone, Glycated Hemoglobin, Analysis of Variance, Meal, business.industry, Insulin, digestive, oral, and skin physiology, food and beverages, General Medicine, medicine.disease, Diabetes Mellitus, Type 1, Basal (medicine), chemistry, Metabolic control analysis, business |
| الوصف: | The aim of this work was to observe whether different types of carbohydrates might require different insulin doses. Five type 1 CSII-treated diabetic subjects (age 39 +/- 4 years), C-peptide negative and in optimal metabolic control (HbA1c 7.5 +/- 0.2) were selected for the study. They were connected to the Biostator 6 times with an interval of 4-10 days between sessions and fed a meal containing 75 g of carbohydrates of different types: bread, pasta, potatoes, apples, oranges and sucrose. The following net (above basal) insulin requirement for the 30 meals were found (IU - mean + SD): bread 9.15 +/- 1.97; pasta 6.00 +/- 1.37; potatoes 7.05 +/- 2.58; apples 4.54 +/- 1.42; oranges 6.21 +/- 2.62; sucrose 7.83 +/- 2.33. A statistically significant difference was found by ANOVA among insulin requirements for foods (p less than 0.05). Single comparisons between bread and the other foods showed a statistically significant difference only between bread and apple (p less than 0.05). Mean coefficient of variation was 33.9% for the subjects and 30.7% for the meals. A significant correlation was found between Jenkins' glycaemic index and insulin requirement (r = 0.897; p less than 0.001). In conclusion, the high intraindividual variability of insulin requirement does not advice the use of the glycaemic index during optimized insulin therapy. |
| تدمد: | 1432-5233 0940-5429 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525363536b45dcec4bfdf09fd486fee1Test https://doi.org/10.1007/bf02732113Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....525363536b45dcec4bfdf09fd486fee1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14325233 09405429 |
|---|