المؤلفون: Sun, Yang, Hu, Lu, Tao, Zhipeng, Jarugumilli, Gopala K, Erb, Hannah, Singh, Alka, Li, Qi, Cotton, Jennifer L, Greninger, Patricia, Egan, Regina K, Tony Ip, Y, Benes, Cyril H, Che, Jianwei, Mao, Junhao, Wu, Xu

المساهمون: Molecular, Cell and Cancer Biology, Program in Molecular Medicine

المصدر: Nature communications ; 13 ; 1 ; 6744 ; United Kingdom ; United States ; England

مصطلحات موضوعية: Cancer therapeutic resistance, Chemical biology, Drug discovery

العلاقة: Nature Communications; https://doi.org/10.1038/s41467-022-34559-0Test; Sun Y, Hu L, Tao Z, Jarugumilli GK, Erb H, Singh A, Li Q, Cotton JL, Greninger P, Egan RK, Tony Ip Y, Benes CH, Che J, Mao J, Wu X. Pharmacological blockade of TEAD-YAP reveals its therapeutic limitation in cancer cells. Nat Commun. 2022 Nov 8;13(1):6744. doi:10.1038/s41467-022-34559-0. PMID: 36347861; PMCID: PMC9643419.; http://hdl.handle.net/20.500.14038/53238Test

الإتاحة: https://doi.org/10.1038/s41467-022-34559-0Test
https://doi.org/20.500.14038/53238Test
https://hdl.handle.net/20.500.14038/53238Test

المؤلفون: Hu, Lu, Sun, Yang, Liu, Shun, Erb, Hannah, Singh, Alka, Mao, Junhao, Luo, Xuelian, Wu, Xu

المساهمون: Molecular, Cell and Cancer Biology

المصدر: eLife ; 11 ; United States ; England

مصطلحات موضوعية: Hippo signaling, biochemistry, chemical biology, co-crytal structure, human, medicinal chemistry, mouse, tead transcription factors

العلاقة: This article is based on a previously available preprint in bioRxiv, https://doi.org/10.1101/2022.05.24.493232Test; eLife; https://doi.org/10.7554/elife.80210Test; Hu L, Sun Y, Liu S, Erb H, Singh A, Mao J, Luo X, Wu X. Discovery of a new class of reversible TEA domain transcription factor inhibitors with a novel binding mode. Elife. 2022 Nov 18;11:e80210. doi:10.7554/eLife.80210. PMID: 36398861; PMCID: PMC9728997.; http://hdl.handle.net/20.500.14038/53211Test

الإتاحة: https://doi.org/10.7554/eLife.80210Test
https://doi.org/20.500.14038/53211Test
https://doi.org/10.1101/2022.05.24.493232Test
https://doi.org/10.7554/elife.80210Test
https://hdl.handle.net/20.500.14038/53211Test

المؤلفون: Nirala, Niraj K., Li, Qi, Ghule, Prachi N., Chen, Hsi-Ju, Li, Rui, Zhu, Lihua Julie, Wang, Ruijia, Rice, Nicholas P., Mao, Junhao, Stein, Janet L., Stein, Gary S., van Wijnen, Andre J., Ip, Y. Tony

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2021 Oct 01. 118(41), 1-11.

الوصول الحر: https://www.jstor.org/stable/27093414Test

المؤلفون: Cotton, Jennifer L, Dang, Kyvan, Hu, Lu, Sun, Yang, Singh, Alka, Rajurkar, Mihir S, Li, Qi, Wu, Xu, Mao, Junhao

المساهمون: Molecular, Cell and Cancer Biology

المصدر: Cell reports ; 40 ; 3 ; 111125 ; United States

مصطلحات موضوعية: AKT, CP: Cell biology, Gli1, LKB1, PTEN, gastrointestinal polyposis, intestinal mesenchyme, mTOR, tumorigenesis

العلاقة: Cell Reports; https://doi.org/10.1016/j.celrep.2022.111125Test; Cotton JL, Dang K, Hu L, Sun Y, Singh A, Rajurkar MS, Li Q, Wu X, Mao J. PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis. Cell Rep. 2022 Jul 19;40(3):111125. doi:10.1016/j.celrep.2022.111125. PMID: 35858546; PMCID: PMC9764383.; http://hdl.handle.net/20.500.14038/52731Test

الإتاحة: https://doi.org/10.1016/j.celrep.2022.111125Test
https://doi.org/20.500.14038/52731Test
https://hdl.handle.net/20.500.14038/52731Test

المؤلفون: Tang, Chih-Min, Lee, Tracy E, Syed, Sabriya A, Burgoyne, Adam M, Leonard, Stephanie Y, Gao, Fei, Chan, Jonathan C, Shi, Eileen, Chmielecki, Juliann, Morosini, Deborah, Wang, Kai, Ross, Jeffrey S, Kendrick, Michael L, Bardsley, Michael R, De Siena, Martina, Mao, Junhao, Harismendy, Olivier, Ordog, Tamas, Sicklick, Jason K

المصدر: Oncotarget. 5

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Clinical Research, Rare Diseases, Digestive Diseases, Genetics, Cancer, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Antineoplastic Agents, Arsenic Trioxide, Arsenicals, Binding Sites, Cell Line, Tumor, Cell Survival, Cilia, Dose-Response Relationship, Drug, Drug Resistance, Neoplasm, Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors, Gene Expression Regulation, Neoplastic, Humans, Imatinib Mesylate, Interstitial Cells of Cajal, Mutation, Nerve Tissue Proteins, Nuclear Proteins, Oxides, Promoter Regions, Genetic, Proto-Oncogene Proteins c-kit, RNA Interference, RNA, Messenger, Receptor, Platelet-Derived Growth Factor alpha, Signal Transduction, Transfection, Zinc Finger Protein GLI1, Zinc Finger Protein Gli2, Zinc Finger Protein Gli3, arsenic trioxide, GIST, GLI, ICC, imatinib-resistant, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0zv0r2d7Test

المؤلفون: Zheng, Zhen, Mao, Junhao, Tan, Xiaofang, Jia, Lijuan, Liu, Tiancheng

المصدر: Environmental Science & Pollution Research; Mar2024, Vol. 31 Issue 13, p19348-19362, 15p

مصطلحات موضوعية: CATALYTIC hydrolysis, LOW temperatures, SODIUM borohydride, CATALYSTS, WATER temperature, CITRIC acid, OZONE layer

المؤلفون: Jung, Roy, Palleti Janardhan, Harish, Dresser, Karen A., Cotton, Jennifer L., Hutchinson, Lloyd, Mao, Junhao, Trivedi, Chinmay M.

المساهمون: Graduate School of Biomedical Sciences, Li-Weibo Institute for Rare Diseases Research, Department of Molecular, Cell, and Cancer Biology, Department of Pathology, Division of Cardiovascular Medicine, Department of Medicine

المصدر: Arteriosclerosis, thrombosis, and vascular biology ; 41 ; 7 ; 2233-2235

مصطلحات موضوعية: heart neoplasms, morbidity, neoplasms, sarcoma, vascular diseases, Cardiovascular Diseases, Pathology

العلاقة: Link to Article in PubMed; Jung R, Janardhan HP, Dresser K, Cotton JL, Hutchinson L, Mao J, Trivedi CM. Sustained Activation of Endothelial YAP1 Causes Epithelioid Hemangioendothelioma. Arterioscler Thromb Vasc Biol. 2021 Jul;41(7):2233-2235. doi:10.1161/ATVBAHA.121.316300. Epub 2021 Jun 3. PMID: 34078092; PMCID: PMC8216595. Link to article on publisher's site; 1079-5642 (Linking); http://hdl.handle.net/20.500.14038/41963Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5800&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/4767Test; oapubs/4767

الإتاحة: https://doi.org/10.1161/ATVBAHA.121.316300Test
https://doi.org/20.500.14038/41963Test
https://hdl.handle.net/20.500.14038/41963Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5800&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/4767Test

المؤلفون: Mia, Masum M., Cibi, Dasan Mary, Abdul Ghani, Siti Aishah Binte, Song, Weihua, Tee, Nicole, Ghosh, Sujoy, Mao, Junhao, Olson, Eric N., Singh, Manvendra K.

المساهمون: Department of Molecular, Cell and Cancer Biology

المصدر: PLoS biology ; 18 ; 12 ; e3000941

مصطلحات موضوعية: Macrophages, Heart, Gene expression, Myocardial infarction, Inflammation, Small interfering RNA, Luciferase, Transfection, Amino Acids, Peptides, and Proteins, Biochemistry, Biophysics, and Structural Biology, Cardiovascular Diseases, Cardiovascular System, Physiology

العلاقة: Link to Article in PubMed; Mia MM, Cibi DM, Abdul Ghani SAB, Song W, Tee N, Ghosh S, Mao J, Olson EN, Singh MK. YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction. PLoS Biol. 2020 Dec 2;18(12):e3000941. doi:10.1371/journal.pbio.3000941. PMID: 33264286; PMCID: PMC7735680. Link to article on publisher's site; 1544-9173 (Linking); http://hdl.handle.net/20.500.14038/41725Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5546&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/4516Test; oapubs/4516

الإتاحة: https://doi.org/10.1371/journal.pbio.3000941Test
https://doi.org/20.500.14038/41725Test
https://hdl.handle.net/20.500.14038/41725Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5546&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/4516Test

المؤلفون: Eder, Noreen, Roncaroli, Federico, Dolmart, Marie-Charlotte, Horswell, Stuart, Andreiuolo, Felipe, Flynn, Helen R., Lopes, Andre T., Claxton, Suzanne, Kilday, John-Paul, Collinson, Lucy, Mao, Junhao, Pietsch, Torsten, Thompson, Barry, Snijders, Ambrosius P., Ultanir, Sila K.

المساهمون: Department of Molecular, Cell and Cancer Biology

المصدر: Nature communications ; 11 ; 1 ; 2380

مصطلحات موضوعية: Cancer models, Cell proliferation, CNS cancer, Phosphorylation, Tumour-suppressor proteins, Amino Acids, Peptides, and Proteins, Cancer Biology, Enzymes and Coenzymes, Molecular and Cellular Neuroscience, Neoplasms, Nervous System, Nucleic Acids, Nucleotides, and Nucleosides

العلاقة: Link to Article in PubMed; Eder N, Roncaroli F, Dolmart MC, Horswell S, Andreiuolo F, Flynn HR, Lopes AT, Claxton S, Kilday JP, Collinson L, Mao JH, Pietsch T, Thompson B, Snijders AP, Ultanir SK. YAP1/TAZ drives ependymoma-like tumour formation in mice. Nat Commun. 2020 May 13;11(1):2380. doi:10.1038/s41467-020-16167-y. PMID: 32404936; PMCID: PMC7220953. Link to article on publisher's site; 2041-1723 (Linking); http://hdl.handle.net/20.500.14038/41477Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5275&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/4256Test; oapubs/4256

الإتاحة: https://doi.org/10.1038/s41467-020-16167-yTest
https://doi.org/20.500.14038/41477Test
https://hdl.handle.net/20.500.14038/41477Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5275&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/4256Test

المؤلفون: Li, Huapeng, Li, Qi, Dang, Kyvan, Ma, Shan, Cotton, Jennifer L., Yang, Sun, Zhu, Lihua Julie, Deng, April C., Ip, Y. Tony, Johnson, Randy L., Wu, Xu, Punzo, Claudio, Mao, Junhao

المساهمون: Department of Pathology, Department of Ophthalmology and Visual Sciences, Program in Molecular Medicine, Department of Molecular, Cell and Cancer Biology

المصدر: Cell reports ; 29 ; 10 ; 3200-3211.e4

مصطلحات موضوعية: AAV ocular injection, Hippo/YAP, Ras/MAPK, dual inhibition, mouse model, tumor initiation, tumor progression, uveal melanoma, Amino Acids, Peptides, and Proteins, Cancer Biology, Enzymes and Coenzymes, Eye Diseases, Molecular Biology, Neoplasms, Ophthalmology, Pathology

العلاقة: Link to Article in PubMed; Cell Rep. 2019 Dec 3;29(10):3200-3211.e4. doi:10.1016/j.celrep.2019.03.021. Link to article on publisher's site; 2211-1247 (Electronic); http://hdl.handle.net/20.500.14038/41301Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5106&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/4087Test; oapubs/4087

الإتاحة: https://doi.org/10.1016/j.celrep.2019.03.021Test
https://doi.org/20.500.14038/41301Test
https://hdl.handle.net/20.500.14038/41301Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5106&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/4087Test