دورية أكاديمية

Cognitive function in ambulatory patients with systolic heart failure: insights from the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial.

التفاصيل البيبلوغرافية
العنوان: Cognitive function in ambulatory patients with systolic heart failure: insights from the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial.
المؤلفون: Graham, Susan, Ye, Siqin, Qian, Min, Sanford, Alexandra R, Di Tullio, Marco R, Sacco, Ralph L, Mann, Douglas L, Levin, Bruce, Pullicino, Patrick M, Freudenberger, Ronald S, Teerlink, John R, Mohr, J P, Labovitz, Arthur J, Lip, Gregory Y H, Estol, Conrado J, Lok, Dirk J, Ponikowski, Piotr, Anker, Stefan D, Thompson, John L P, Homma, Shunichi, WARCEF Investigators, Homma, S, Thompson, J L P, Pullicino, P, Freudenberger, R, Graham, S, Teerlink, J, Ammon, S, Mann, D, Sacco, R L, Massie, B, Anker, S, Labovitz, A, Moy, C, Gilbert, P, Gutmann, L, Marler, J, Mejia, V, Gabriel, A, Czaja, P, Gaciong, Z, Gora, J, Kleinrok, A, Prokop-Lewicka, G, Haddad, H, Davies, R, Sitwell, L, Donaldson, J, To, T, Yufe, R, Donelly, B, Huynh, T, Cote, R, St Jacques, B, Borts, D, Tullio, G, Sindilar, A M, Winder, T, Janzen, E, Walker, C, Moe, G, Bayer, N, Konig, A, Arnold, M, Spence, D, Smith, J, Bessoudo, R, Bailey, P, McNulty, A, Nawaz, S, Dewar, C, Rajda, M, MacFarlane, M, Minuk, J, Schanz, C, Penn, A, Atkins, L, Ducharme, A, Brown, H, Zieroth, S, Muñoz, A, Lok, D, ten Holter, J B M, Huls, C, Bruggink-Andre, P, van Bujisen-Nutters, A, Ziekenhuis, Daniels, M, Coppes, A, van Zagten, M, Elzebroek, N, Hamroui, K, de Kort, P L M, Vuijsters, J, Holwerda, N, Hermans, W, van der Loo, R, Wajon, E, Hageman, G, Buchem-Damming, G v, Ronner, E, Wissenburg-van Lieshout, A, Niekus, H, van Hessen, M W J, Verheul, G A M, Linssen, G, te Pas, L, Plomp, J, de Milliano, P A R, Breedveld, R, Bos, M J, Houra, M, Beran, D, Lebedova, R, Carda, J, Bednarova, E, Vosmerova, J, Marcinek, G, Drasnar, T, Najmanova, O, Dunaj, M, Pechackova, E, Kuchar, M, Jansky, P, Simon, J, Dvorakova, H, Gregor, P, Maruskova, M, Svoboda, L, Lorenc, Z, Kralicek, P, Pollak, L, Krobot, M, Spinar, J, Nemec, M, Spinarova, L, Kuba, R, Padour, F, Padourova, I, Padour, M, Michalova, M, Golan, L, Hajkova, M, Povolny, J, Krizova, L, Horak, D, Kucera, P, Malek, I, Krizova, B, Svoboda, J, Ferkl, R, Regos, L, Csuros, L, Lovasz, O, Kiss, G, Timar, S, Torok, N, Hajnalne, A, Palossy, B, Nagy, A, Fulop, P, Jakab, G, Ronaszeki, A, Bodi, M, Satori, M, Edes, I, Varga, I, Kovacs, A, Berente, L, Péterfai, E, Pauer, R, Toth, K, Nagy, E, Benczur, B, Karsay, K, Végh, T, Nagy, R, Karpati, P, Davidovits, Z, Borbola, J, Vanyi, J, Oze, B, Bujdoso, A, Kosa, I, Baliko, L, Natour, M, Morgil, M, Hartmann, E, Morgil, H, Winkler, R, Gass, S, Baumann, S, Jeserich, M, Rodl, J, Dzaiy, M, Turhan, G, Wolf, K, Genth-Zotz, S, Siebert, T, Jakobs, C, Kiorwantsi, M, Pieske, B, Wachter, R, Schoenauer, M, Voigt, S, Schunkert, H, Boguschewski, A, Resch, M, Wensel, R, Schumann, V, Heidrich, P, Girina, O, Prokopovych, Y, Lebedynska, M, Sorokina, I, Karpenko, O, Brodi, N, Klochkov, S, Voronkov, L, Besaga, Y, Novikova, O, Amosova, K, Yaremenko, O, Balaban, K, Kovalenko, V, Polenova, N, Sakharchuk, I, Ogorodnichuk, A, Rudenko, L, Tutov, Y, Parkhomenko, A, Kozhukhov, S, Yakimenko, E, Kolomiets, S, Yurlov, V, Tikhonova, S, Estol, C, Elizalde, A, Mangariello, B, Zaidman, C, Guerlloy, F, Gitelman, P, Crotto, K, Sassone, S, Aiub, J, Novoa, F, Lopez Santi, R, Romia, P, Montaña, O, Malchik, D, F Sokn, Schygiel, P, Porcile, R, Soria Tito, F, Thierer, J, Avellana, P, Rapallo, C, Calderon, M, MacFadyen, R, Haynes, R, Partridge, J, Dérera, L, Kokles, M, Mehe?ová, S, Zachar, A, Hranai, M, Varadyova, T, Göbö, T, Litvinova, J, Loviska, P
المساهمون: Klinik für Herz- und Kreislauferkrankungen
سنة النشر: 2014
المجموعة: Munich University of Technology (TUM): mediaTUM
مصطلحات موضوعية: info:eu-repo/classification/ddc
الوصف: We sought to determine whether cognitive function in stable outpatients with heart failure (HF) is affected by HF severity. A retrospective, cross-sectional analysis was performed using data from 2, 043 outpatients with systolic HF and without prior stroke enrolled in the Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Trial. Multivariable regression analysis was used to assess the relationship between cognitive function measured using the Mini-Mental Status Exam (MMSE) and markers of HF severity (left ventricular ejection fraction [LVEF], New York Heart Association [NYHA] functional class, and 6-minute walk distance). The mean (SD) for the MMSE was 28.6 (2.0), with 64 (3.1%) of the 2,043 patients meeting the cut-off of MMSE<24 that indicates need for further evaluation of cognitive impairment. After adjustment for demographic and clinical covariates, 6-minute walk distance (?-coefficient 0.002, p<0.0001), but not LVEF or NYHA functional class, was independently associated with the MMSE as a continuous measure. Age, education, smoking status, body mass index, and hemoglobin level were also independently associated with the MMSE. In conclusion, six-minute walk distance, but not LVEF or NYHA functional class, was an important predictor of cognitive function in ambulatory patients with systolic heart failure.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: https://mediatum.ub.tum.de/1328069Test
الإتاحة: https://mediatum.ub.tum.de/1328069Test
حقوق: info:eu-repo/semantics/restrictedAccess
رقم الانضمام: edsbas.803BEEBF
قاعدة البيانات: BASE