دورية أكاديمية
Clomiphene Citrate versus Clomiphene Citrate in combination with other drugs in Ovulation Induction in Patients with Polycystic Ovary Syndrome
| العنوان: | Clomiphene Citrate versus Clomiphene Citrate in combination with other drugs in Ovulation Induction in Patients with Polycystic Ovary Syndrome |
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| المؤلفون: | Mostafa Khodary, Yasser Ahmed Abuelwafa Abdellatif, Mahmoud Ibrahim Almolakab B- Alrashidy, Sayed Ahmed Mohammed Taha |
| المصدر: | SVU - International Journal of Medical Sciences, Vol 7, Iss 2, Pp 1-8 (2024) |
| بيانات النشر: | South Valley University, Faculty of Medicine, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | anovulation pcos clomiphene citrate tamoxifen, metformin letrozole gonadotrophins, ovulation induction endometrium, Medicine |
| الوصف: | Background: Polycystic ovary syndrome (PCOS) is the most prevalent cause of normogonadotrophic anovulation, also classified as World Health Organization group II anovulation. Objectives: The aim of this study was to compare the effectiveness and clinical outcomes of clomiphene citrate alone and with different combinations (metformin , tamoxifen , letrozole and low dose gonadotrophins ) in induction of ovulation in women with PCOS. Patients and methods: The Obstetrics and Gynecology department at Qena University Hospital, South Valley University, was the site of this randomized study. The study included 400 infertile cases with PCOS divided on 5 groups . The duration of the study ranged from 12-24 months. Results: In the studied groups, group 4 (clomiphene and letrozole ) and group 5 (clomiphene and low dose gonadotrophins) had the highest ovulation rate which was 31.3 % , 41.3 % respectively and also the highest pregnancy rate which was 33.8 % for each group . Conclusion: The combination of clomiphene and letrozole and clomiphene and gonadotrophins had proved to be the most effective , low cost infertility treatment in women with PCOS that offers high ovulation and pregnancy rates. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2735-427X 2636-3402 |
| العلاقة: | https://svuijm.journals.ekb.eg/article_356800.htmlTest; https://doaj.org/toc/2735-427XTest; https://doaj.org/toc/2636-3402Test |
| DOI: | 10.21608/SVUIJM.2023.194749.1534 |
| الوصول الحر: | https://doaj.org/article/3e39a76e51b44a959546dfea1f37b96dTest |
| رقم الانضمام: | edsdoj.3e39a76e51b44a959546dfea1f37b96d |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 2735427X 26363402 |
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| DOI: | 10.21608/SVUIJM.2023.194749.1534 |