التفاصيل البيبلوغرافية
العنوان:
I-CARE, a European Prospective Cohort Study Assessing Safety and Effectiveness of Biologics in Inflammatory Bowel Disease
المؤلفون:
Laurent Peyrin-Biroulet , Jean-François Rahier , Julien Kirchgesner , Vered Abitbol , Sebastian Shaji , Alessandro Armuzzi , Konstantinos Karmiris , Javier P. Gisbert , Peter Bossuyt , Ulf Helwig , Johan Burisch , Henit Yanai , Glen A. Doherty , Fernando Magro , Tamás Molnar , Mark Löwenberg , Jonas Halfvarson , Edyta Zagorowicz , Hélène Rousseau , Cédric Baumann , Filip Baert , Laurent Beaugerie , Jean-Marc Gornet , Jean-Marie Reimund , Xavier Hebuterne , Aurélien Amiot , Franco Armelao , Pierre Blanc , Claudio Papi , Guillaume Pineton De Chambrun , Xavier Roblin , null Chu , Sohail Shariq , Nikolaos Viazis , Jimmy Limdi , Piotr Eder H , Georgios Michalopoulos , Andrew Bell , Livia Biancone , Marie Dewitte , Zia Mazhar , Denis Franchimont , Stephane Nancey , Gilles Macaigne , Maria Beatrice Principi , Mathurin Fumery , Gareth Parkes , Jean-Christophe Valats , Glen Doherty , Guillaume Bouguen , Hersin Tsai , Mohsin Gangi , Natalia Pedersen , Frédéric Heluwaert , Richard Shenderey , Sebastian Zeissig , Jeffrey Butterworth , Fabiana Castiglione , Lynsey Corless , Camille Zallot , Salil Singh , Sunil Sonwalkar , Elizabeth Clayton , Deven Vani , Guy Bellaiche , Martine De Vos , Uri Kopylov , Triana Lobaton , Christophe Locher , Gerassimos Mantzaris , George Abouda , Katie Smith , Michael Sprakes , Angeliki Theodoropoulou , Emma Wesley , Joëlle Bonnet , David Elphick , Cyrielle Gilletta , John Gordon , David Laharie , Antoine Nakad , Ambrogio Orlando , Patrick Dubois , Peter Hasselblatt , Christophe Michiels , Cathryn Preston , Anca Staicu , Lucine Vuitton , Mehdi Kaassis , Ally Speight , Deb Ghosh , Nicolas Mathieu , Anne-Laure Pelletier , Anne Phillips , Romain Altwegg , Irit Avni , null biron , Jonathon Landy , Maria Nachury , Achuth Shenoy , Caroline Trang , Georgios Bamias , Klaudia Farkas , Christian Maaser , Ariella Shitrit , Britta Siegmund , Jérôme Filippi , Colm O'morain , Laurent Costes , David Hobday , Zoltán Szepes , Emma Calabrese , Helen Dallal , Michael Fung , Arvind Ramadas , Bijay Baburajan , Konrad Koss , Christophe Barberis , Anthony Buisson , Morgane Amil , Paola Balestrieri , Matthew Johnson , Maria Tzouvala , Stéphanie Viennot , Ferenc Nagy , Nick Thompson , Laurent Alric , Sunil Samuel , Anne Bourrier , Elise Chanteloup , Emilie Del Tedesco , Marcus Harbord , Alan Lobo , Sally Myers , Richard Pollok , Tariq Ahmad , Rakesh Chaudhary , Christos Karakoidas , Ashraf Soliman , Carmen Stefanescu , Georgios Theocharis , Stijn Vanden Branden , Belén Beltran , Yoram Bouhnik , Arnaud Bourreille , Joana Branco , Ben Colleypriest , Rami Eliakim , Paul Knight , Aoibhlinn O'toole , Virgina Robles , Konstantinos Triantafyllou , Marta Maia Bosca , Guy Lambrecht , Lucia Marquez Mosquera , Simon Panter , Aikaterini Pappa , Marion Simon , Ganesh Sivaji , Christophe Bellanger , Arthur Belle , Natalia Borruel , Laurence Egan , Harald Peeters , Daniel Sharpstone , Ramesh Arasaradnam , José Manuel Benitez , Jens Frederik Dahlerup , Olga Giouleme , Miguel Minguez , Eftychia Tsironi , Angela Variola , Patrick Allen , Lucille Boivineau , Andy Cole , Nina Dib , Fernando Gomollon , Richard Johnston , Konstantinos Katsanos , Nick Kennedy , Marianne Kiszka-Kanowitz , Ignacio Marin-Jimenez , Pál Miheller , Pilar Nos , Othman Saraj , Lars Vinter-Jensen , Eran Zittan , Clotilde Baudry , Xavier Calvet , Marie-Christine Cazelles-Boudier , Jean-Louis Coenegrachts , Garret Cullen , Marco Daperno , Anjan Dhar , Romain Gerard , Nanna Jensen , Nitsan Maharshak , Mark Mcalindon , Simon Mcloughlin , Miles Parkes , Kamal Patel , Armando Peixoto , Dimitrios Polymeros , Francisco Portela , Rodolfo Rocca , Philippe Seksik , Sreedhar Subramanian , Ruth Tennenbaum , Raja Atreya , Oliver Bachmann , Arthur Berger , Renáta Bor , Maire Buckley , Daniel Carpio , María Chaparro , Francesco Costa , Eugeni Domenech , Maria Esteve , Stephen Foley , Jordi Guardiola , Ioannis Koutroubakis , Tanja Kuehbacher , Cécilia Landman , Alessandro Lavagna , Noemí Manceñido , Míriam Mañosa , Maria Dolores Martín-Arranz , Laurianne Plastaras , Maria Lia Scribano , Subhasish Sengupta , Nils Teich , My-Linh Tran-Minh , Evanthia Zampeli , Leila Amininejad , Teresa Arroyo , Alain Attar , Ann-Sofie Backman , Anita Bálint , John Beckly , Shomron Ben Horin , Sónia Bernardo , Ludovic Caillo , Bénédicte Caron , María Shanika de Silva , Anna FábiáN , Gionata Fiorino , Ana Gutierrez , Adi Lahat , Mohamed Masmoudi , Marco Mendolaro , Vinciane Muls , Florian Poullenot , Christopher Probert , Catherine Reenaers , Mariann Rutka , Zaman Sarwari , Joanne Sayer , Beatriz Sicilia , Helena Sousa , Catherine van Kemseke , Yamile Zabana , Marco Astegiano , Paul Banim , Dominik Bettenworth , Médina Boualit , Jacob Broder Brodersen , Angeliki Christidou , Rachel Cooney , João Cortez Pinto , Portugal Marília Cravo , Anneline Cremer , Silvio Danese , Antonio di Sabatino , Jan Fallingborg , Antonio Ferronato , Esther Garcia Planella , Sanjay Gupta , Eran Israeli , Samantha Kestenbaum , Lone Larsen , Elisabeth Macken , Nicoletta Mathou , Ágnes Milassin , Joanna Pofelski , Chiara Ricci , Francisco Rodriguez-Moranta , Martin Schmidt-Lauber , Ian Shaw , Marta Soares , Heithem Soliman , Christos Triantos , Konstantinos Zografos , Anurag Agrawal , Alexandre Aubourg , Manuel Barreiro-de Acosta , Jesús Barrio , Daniel Bergemalm , Fernando Bermejo , Giorgia Bodini , Johan Bohr , Dimitrios Christodoulou , Christophe Claessens , Paul Collins , Ruth de Francisco , Santiago Garcia , Sotirios Georgopoulos , Felix Goutorbe , Chrisostomos Kalantzis , Anastasia Kourikou , Vincent Mace , Georgia Malamut , Paula Ministro , Isabelle Nion Larmurier , Elena Ricart , Mélanie Serrero , Juliette Sheridan , Petra Weimers , Vibeke Andersen , Bruno Arroja , Bernd Bokemeyer , Luis Bujanda , Thibault Degand , Carl Eriksson , Cécile Garceau , Henning Glerup , Idan Goren , Lucina Jackson , Stéphane Koch , Francisco Mesonero , Ingrid Ordas , Pauline Riviere , Simone Saibeni , João Soares , Noémie Tavernier , Klaus Theede , Bella Ungar , Elke Bästlein , Antonio Gasbarrini , Andreas Protopapas , Wolfgang Reindl , Fabrizio Bossa , Ailsa Hart , Franz-Josef Heil , Anthony O'Connor , Bas Oldenburg , Luca Pastorelli , null Stephen patchett , Subramaniam Ramakrishnan , John de Caestecker , Ana Echarri , David Kevans , Jürgen Büning , Rosa Coelho , Jeroen Jansen , Benjamin Koslowski , Christopher Wells , Daniel Ceballos , Ingrid König , Hari Padmanabhan , Timi Patani , Raheel Qureshi , Matthieu Allez , Emmanouil Archavlis , Delphine Bonnet , Luisa Guidi , Deirdre Mcnamara , Piero Vernia , Michael Weidenhiller , Lang Alon , Trine Boysen , Charlotte Delattre , Richard Farrell , Rolf-Achim Krüger , Thierry Paupard , Ida Vind , Flavio Caprioli , Vladimir Gancho , Vincent Quentin , Benjamin Avidan , Geert D’Haens , Jane Mccarthy , Jonathon Snook , Konstantinos Soufleris , Frank Zerbib , Dan Carter , Annekatrien Depla , Thomas Eisenbach , Walter Fries , Nikolaos Grammatikos , Saskia Ilegems , Antonio Lopez-Sanroman , Jacques Moreau , Gabriele Riegler , Svend Rietdijk , Marta Rocha , Isabelle Rosa , Barbara Ryan , Yelena Yeremenko , Arnaud Boruchowicz , Filipe Damião , Foteini Laoudi , Andreas Lügering , Giampiero Macarri , Konstantinos Thomopoulos , Luísa Barros , Thomas Blixt , Aurélien Garros , Sam Khorrami , Harry Sokol , Andreas Sturm , Dan Livovsky , Jochen Maul , Heinrich Miks , Vasileios Papadopoulos , Carsten Schmidt , Yifat Snir , Lise Svenningsen , Wafaa Ahmed , Yelena Broitman , Emmanuel Cuillerier , Prashant Kant , Jan Leyden , Lev Lichtenstein , Susana Lopes , Chloé Martineau , Hugh Mulcahy , Axel Schweitzer , Fiona Van Schaik , Hagar Banai , Pauline Danion , Charlotte Dulery , Herma Fidder , Claire Gay , Hervé Hagege , Florence Harnois , Søren Peter Jørgensen , Jens Müller-Ziehm , Michail Oikonomou , Carolina Palmela , Jörg Schulze/Röske , Mark Smith , Tamar Thurm , Francesca Bresso , Hedia Brixi , John Jones , Padraig Macmathuna , Claire Painchart , Yulia Ron , Marianne Vester-Andersen , Gonçalo Alexandrino , Norbert Börner , Mariana Cardoso , Cristina Chagas , Axel Dignaß , Iris Dotan , Charlotte Hedin , Pantelis Karatzas , Panagiotis Kasapidis , Károly Palatka , Georgios Sakizlis , Ana Wilson , Nick Bosanko , Paulo Caldeira , Charlotte Gagniere , Louise Libier , Camille Meunier , Gero Moog , Audrey Pasquion , Roberta Pica , Ayesha Akbar , Nadia Arab , Guillaume Cadiot , João Carvalho , Claire Charpignon , Laus Fellermann , Sigal Fishman , Gerald Fraser , Nathan Gluck , Mark Hoesl , Jarosław Kierkus , Maria Klopocka , Eduardo Martin Arranz , Luis Menchen , Susanna Nikolaus , Anca Petrache , Cyriel Ponsioen , Sabino Riestra , Pilar Robledo , Cristina Rodriguez , Misheal Samer , Matthias Tischer , Joanna Wypych , Julien Baudon , Cristina Bezzio , Gilles Boschetti , Tom Creed , Maria Giulia Demarzo , Stefano Festa , Andrés Figueroa , Mette Julsgaard , Pablo Navarro , Pablo Perez-Galindo , Cléa Rouillon , Emanuele Sablich , Joan Tosca , Mathias Vidon , Marine Vidon , René-Louis Vitte , Anne Wampach , Isabelle Clerc Urmes , Marc Borie , Mathieu Uzzan , Kelly Chatten , Rimmer Peter , Iqbal Tariq , Marta Cossignani , Fiorella Cañete , Tom Holvoet , Susanne Krasz , Sandra Dias , Hadas Abalia , Aziza Abaza , Gal Abramovich , Ingrid Ackzell , Carol Adams , Catherine Addleton , Erika Alfambra , Alicia Algaba , Clare Allcock , Joanna Allison , Karine Amouriaux , Julie Anderson , Emma Anderson , Saskia Appelmans , Lisa Armstrong , Stacey Atkins , Masoumeh Attaran-Bandarabadi , Yvonne Bailey , Stephanie Bardot , Natasha Beck , Lillie Bennett , Jonathan Phil Bergfeld , Ramdane Berkane , Hanne Boey , Louise Bowlas , Joanne Bradley-Potts , Tracy Brear , Nicole Bretlander-Peters , Ellen Brown , Johanna Brown , Elizabeth Buckingham , Katrien Buellens , Rhian Bull , Maura Burke , Leighanne Burns , Julie Burton , Agness Bwalya , Karine Cabanas , Muriel Callaghan , Océane Camou , Debbie Campbell , Elvira Capoferro , Mandy Carnahan , Cornelia Carnio , Anne Carter , Concetta Casali Clack , Leïla Chedouba , Bessie Cipriano , Sophie Claeys , Manon Closset , Dilek Coban , Sara Cococcia , Carolann Coe , Helen Cole , Emilie Collet , Kayleigh Collins , Isabelle Combes , Emma Connor , Kathryn Constantin , Susan Cooke , Nathanaëlle Cornet , Estelle Corrihons , Pilar Corsino , Rosie Cortaville , Donna Cotterill , Amanda Cowton , Harriet Cox , Viktoria Cripps , Amanda Crowder , Tzufit Cukier , Amelia Daniel , Chris Dawe , Jose de Haan , Rosanna de la Croix , Evva Dejonckheere , Juan Delare Villanegro , Guillaume Delaval , Mariangela Delliponti , Aude Delommez , Emilie Detry , Melanie Dhanaratne , Laura Diez Galan , Marie Dodel , Emma Dooks , Joseph Du Cheyron , Linda Duane , Jennifer Dulling Vulgo Cochran , Simona Dyer , Harvey Dymond , Charlotte Ekblad , Kerry Elliott , Ingrid Emmerson , Irène Eugene-Jolchine , Lorna Fleming , Eve Fletcher , Sarah Ford , Greg Forshaw , Angela Foulds , Caroline Francois , Nicole Fuge , Gal Gafni , Miri Ganon , Olga Garcia Nuñez , Laura Garcia Ramirez , Sophie Gelder , Raimonda Gettkowski , Daniela Gilardi , Paolo Giuffrida , Vincent Gobert , Jo Godden , Nuala Godwin , Kay Goulden , Sharon Graham , Charlotte Green , Marie Green , Aboubakar Gueye , Tuba Guler , Ida Gustavsson , Helena Hadjisavvas , Fiona Hammonds , Christina Hantzi , Marion Hauke , Julie Haydock , Orla Hayes , Lizette Helbo Nislev , Jessica Hochstodter , Ashleigh Hogg , Manuela Hölbing , Maureen Holland , Maartje Holsbergen , Linda Howard , Aviya Hoyda , Robert Hull , Jane Irish , Wendy Jackson , Wendy Janssen , Lesley Jeffrey , Sofia Jourdan , Izabela Jutrowska , Chava Kaniel , Theofilos Karezos , Niamh Kelly , Jessica Kelly , Mary Kennedy , Una Kennedy , Joyce Kibaru , Gemma Kirkman , Janine Klaproth , Corinna Kneese , Andrea Koch , Kathleen Kokke , Martha Koppelow , Sabine Krause , Sabine Krauspe , Petra Kwakkenbos , Nunzia Labarile , Hannah Lang , Marianne Lassailly , Martine Leconte , Linda Lepczynski , Emma Levell , Nina Levhar , Kerstin Lindhort , Jessica Lisle , Beatriz Lopez Cauce , Gabriele Lorenz , Ambra Lovati , Tracey Lowry , Margareta Lund , Anne Lutz Vorderbrügge , Suzanne Maansson , Videsheka Madapathage , Maelys Cheviakoff , Alison Magness , Orla Manley , Catherine Manyoni , Ingke Marg , Antonella Marra , Carole Martins , Arianna Massella , Aurore Mathias , Danielle Mervyn , Charlotte Minsart , Sally Mitchell , Kathleen Monks , Mélanie Montero , Alson Moore , Maren Moser , Alison Moss , Angela Mullen , M. Francisca Murciano , Deanna Naylor , Ansgar Nehus , Anne Nicholson , Sarah Nöding , Sinead Nolan , Janet Nörenberg , Clare Northcott , Jim O'Connell , Alison O’Kelly , Noam Orbach-Zingboim , Judit Orobitg , Charlene Otieno , Charlotte Owen , Sarah Patch , Maor Pauker , Renate Pauli , Harriet Pearson , Falgon Peggy , Séverine Petit , Christine Petrissans , Simona Piergallini , Lucy Pippard , Laura Pitt , Gabriella Pócsik , Yoann Poher , Chloé Pomes , Lucy Pritchard , Laura Puchades , Sheena Quaid , Aleem Rana , Dana Raynard , Mykla Reilly , Sonja Reinert , Manuela Reinknecht , Baerbel Renner , Rob Reynolds , Giulia Rizzuto , Matthew Robinson , Joke Robrechts , Eva M. Rodriguez , Efrat Rosenblum , Tamlyn Russel , Ibiyemi Sadare , Noa Salama , Toos Schakel , Anja Schauer , Elisa Schiavoni , Caroline Shaw , Sarah Shelton , Virginie Sicart , Elodie Siouville , Orla Smith , Théo Soude , Sophie Stephenson , Elaine Stephenson , Marjan Steppe , An Sterkx , Jo Stickley , Kathleen Sugrue , Natalia Swietec , Charlotte Tasiaux , Bhavneet Thamu , Susane Thomas , Ogwa Tobi , Kahina Touabi , Shifra Tovi , Julie Tregonning , Laura Turchini , Julia Unkhoff , Olesya Unruh , Nurcan Uzun , Frauke Van Aert , Sandrine Vanden Bergh , Louise Vandenbroucke , Laura Vansteenkiste , Shay Vardit , Valentin Vergriete , Elaine Walker , Eleanor Warner , Olivia Watchorn , Ekaterina Watson , Marie-Claire Wauthier , Belgium Maria Weetman , Margaret Weston , Wiebke West-Petroschka , Susann Wienecke , Kerstin Wierling , Miriam Wiestler , Rebecca Wilcox , Elva Wilhelmsen , Angharad Williams , Georgina Williamson , Deborah Wilson , Kate Wistance , Nicolas Wortmann , Subie Wurie , Karin Yadgar , Gail Young , Megan Young , Julien Aucouturier , Marie- Jo Bertin , Hasnae Bougrine , Marie Coisnon , Antoine Defrance , Kati Gutierrez , Amel Harouz , Laure Jerber , Aida Khlifi , Amina Kirati , Nasaladjine Liworo , Maude Logoltat , Charlotte Mailhat , Chancely M'Bayi , Yasmina Medane , Dalal Merkhoufa , Saouda Mohamed Elhad , Bertille Monthe , Fanny Moyon , Pascaline Rabiega , Jennifer Sekela , Charlotte Thilloy , Naima Hamamouche , Frederic Partisotti , Patrick Blandin , Hocine Mokhtari , Laure Coutard
المساهمون:
UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de gastro-entérologie, Gastroenterology and hepatology, Gastroenterology and Hepatology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
المصدر:
I-CARE Collaborator Group 2022, ' I-CARE, a European Prospective Cohort Study Assessing Safety and Effectiveness of Biologics in Inflammatory Bowel Disease ', Clinical Gastroenterology and Hepatology . https://doi.org/10.1016/j.cgh.2022.09.018Test https://doi.org/10.1016/j.cgh.2022.09.018Test
سنة النشر:
2022
مصطلحات موضوعية:
Biological Products , Hepatology , Efficacy , Lymphoma , Tumor Necrosis Factor-alpha , Inflammatory Bowel Disease , Gastroenterology , Biologics , Crohn Disease/diagnosis , Inflammatory Bowel Diseases/chemically induced , Colitis, Ulcerative/diagnosis , Cohort Studies , Necrosis , Immunologic Factors/adverse effects , Humans , Female , 03.02. Klinikai orvostan , Prospective Studies , Safety , I-CARE , Cancer , Immunosuppressive Agents
الوصف:
BACKGROUND AND AIMS: There is a need to evaluate the benefit-risk ratio of current therapies in inflammatory bowel disease (IBD) patients to provide the best quality of care. The primary objective of I-CARE (IBD Cancer and serious infections in Europe) was to assess prospectively safety concerns in IBD, with specific focus on the risk of cancer/lymphoma and serious infections in patients treated with anti-tumor necrosis factor and other biologic monotherapy as well as in combination with immunomodulators.METHODS: I-CARE was designed as a European prospective longitudinal observational multicenter cohort study to include patients with a diagnosis of Crohn's disease, ulcerative colitis, or IBD unclassified established at least 3 months prior to enrollment.RESULTS: A total of 10,206 patients were enrolled between March 2016 and April 2019, including 6169 (60.4%) patients with Crohn's disease, 3853 (37.8%) with ulcerative colitis, and 184 (1.8%) with a diagnosis of IBD unclassified. Thirty-two percent of patients were receiving azathioprine/thiopurines, 4.6% 6-mercaptopurine, and 3.2% methotrexate at study entry. At inclusion, 47.3% of patients were treated with an anti-tumor necrosis factor agent, 8.8% with vedolizumab, and 3.4% with ustekinumab. Roughly one-quarter of patients (26.8%) underwent prior IBD-related surgery. Sixty-six percent of patients had been previously treated with systemic steroids. Three percent of patients had a medical history of cancer prior to inclusion and 1.1% had a history of colonic, esophageal, or uterine cervix high-grade dysplasia.CONCLUSIONS: I-CARE is an ongoing investigator-initiated observational European prospective cohort study that will provide unique information on the long-term benefits and risks of biological therapies in IBD patients. (EudraCT, Number: 2014-004728-23; ClinicalTrials.gov, Number: NCT02377258).
وصف الملف:
text
اللغة:
English
تدمد:
1542-3565
الوصول الحر:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97735daf0f33965fee767e22a220b0b5Test https://research.vumc.nl/en/publications/bce28d90-4f1b-4dc0-a7dd-60c0598d448cTest
حقوق:
OPEN
رقم الانضمام:
edsair.doi.dedup.....97735daf0f33965fee767e22a220b0b5
قاعدة البيانات:
OpenAIRE
