دورية أكاديمية
HIV RNA Suppression during and after Pregnancy among Women in the HIV Outpatient Study, 1996 to 2015
| العنوان: | HIV RNA Suppression during and after Pregnancy among Women in the HIV Outpatient Study, 1996 to 2015 |
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| المؤلفون: | Monita Patel PhD, MPH, Ellen Tedaldi MD, MACP, Carl Armon PhD, Steven Nesheim MD, Margaret Lampe RN, MPH, Frank Palella MD, Richard Novak MD, Madeline Sutton MD, MPH, Kate Buchacz PhD |
| المصدر: | Journal of the International Association of Providers of AIDS Care, Vol 17 (2018) |
| بيانات النشر: | SAGE Publishing, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: | Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: | Objective: To examine HIV viral suppression during/after pregnancy. Design: Prospective observational cohort. Methods: We identified pregnancies from 1996 to 2015. We examined HIV RNA viral load (VL), VL suppression (≤500 copies/mL), and antiretroviral therapy (ART) status at pregnancy start, end, and 6 months postpartum. We estimated risk ratios (RRs) and 95% confidence intervals (CIs) for VL nonsuppression. Results: Among 253 pregnancies analyzed, 34.8% of women exhibited VL suppression at pregnancy start, 60.1% at pregnancy end, and 42.7% at 6 months postpartum. Median VL (log 10 copies/mL) was 2.80 (interquartile range [IQR]: 1.40-3.85) at pregnancy start, 1.70 (IQR: 1.40-2.82) at pregnancy end, and 2.30 (IQR: 1.40-3.86) at postpartum. Risk of postpartum VL nonsuppression was also lower among women on ART and with VL suppression at pregnancy end (versus those not; adjusted RR = 0.30, 95% CI: 0.17-0.53). Conclusions: Maintaining VL suppression among US women remains a challenge, particularly during postpartum. Achieving VL suppression earlier during pregnancy benefits women subsequently. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2325-9582 23259574 |
| العلاقة: | https://doaj.org/toc/2325-9582Test |
| DOI: | 10.1177/2325957417752259 |
| الوصول الحر: | https://doaj.org/article/b29c64d127054c6faf126b3ce0f1093dTest |
| رقم الانضمام: | edsdoj.b29c64d127054c6faf126b3ce0f1093d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23259582 23259574 |
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| DOI: | 10.1177/2325957417752259 |