التفاصيل البيبلوغرافية
| العنوان: |
The second round of a population-based seroprevalence study of anti-SARS-CoV-2 antibodies and the assessment of COVID-19 vaccination in the Republika Srpska, Bosnia and Herzegovina |
| المؤلفون: |
Acimovic, Jela, Mijović, Biljana, Mašić, Srđan, Petkovic, Miroslav, Sladoje, Dragana Puhalo, Knežević, Darija, Dević, Jelena Đaković, Spaić, Dragan, Mašić, Jelena Vladićić, Bokonjić, Dejan, Palo, Mirza, VAUGHAN, Aisling, Pebody, Richard, Nardone, Anthony, Škrbić, Ranko |
| بيانات النشر: |
Authorea, Inc. |
| سنة النشر: |
2023 |
| المجموعة: |
The Winnower (via CrossRef) |
| الوصف: |
Introduction: The aim of the study was to assess the seroprevalence of SARS-CoV-2 in the Republika Srpska, Bosnia and Herzegovina, after five waves of COVID-19 and one year after introduction of vaccination to better understand the true extent of the COVID-19 pandemic and role of vaccination in achieving herd immunity. Methods: The population-based study was conducted from December 2021 to February 2022 in a group of 4,463 individuals from the Republika Srpska. Total anti-SARS-CoV-2 antibodies were determined in serum specimens using the Wantai total antibody ELISA assay and Kantaro Quantitative IgG assays. Results: The overall cumulative seroprevalence was 94.6%. Of all participants, 61.3% were vaccinated against COVID-19. Significantly higher seroprevalence rates were observed among vaccinated participants. Among various professions, the highest seroprevalence was found in the service industry (98.1%), education (98.0%) and healthcare (96.9%). This study found that 2.2% of vaccinated participants, and 3.6% of individuals with SARS-CoV-2 positivity during 2021, had no detectable IgG antibodies. Both seroprevalence and antibody titres were significantly higher in people with hybrid immunity. Conclusion: Our findings reveal a 2,3-fold increase in seroprevalence of SARS-CoV-2 antibodies due to infection and vaccination, comparing to the first study performed one year earlier. This study provides better understanding of the SARS-CoV-2 transmission and highlights the important role of the vaccination in achieving the population immunity. Periodically conducted population-based seroprevalence studies are important for assessment of surveillance system performance and public compliance with vaccination policies. Keywords: COVID-19, SARS-CoV-2 antibodies, seroprevalence, population-based study, Bosnia and Herzegovina, UNITY, SEROPREV. |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| DOI: |
10.22541/au.169650912.25187922/v1 |
| الإتاحة: |
https://doi.org/10.22541/au.169650912.25187922/v1Test |
| رقم الانضمام: |
edsbas.3BDE9AB5 |
| قاعدة البيانات: |
BASE |
