المؤلفون: Xavier, Mary-Ann, Rezende, Fernando, Titze-de-Almeida, Ricardo, Cornelissen, Bart

المصدر: Xavier , M-A , Rezende , F , Titze-de-Almeida , R & Cornelissen , B 2021 , ' BRCAness as a Biomarker of Susceptibility to PARP Inhibitors in Glioblastoma Multiforme ' , Biomolecules , vol. 11 , no. 8 , 1188 . https://doi.org/10.3390/biom11081188Test

مصطلحات موضوعية: glioblastoma, PARP, PARP inhibitors, BRCAness, DNA-DAMAGE RESPONSE, VELIPARIB ABT-888, MUTANT-CELLS, TUMORS, TEMOZOLOMIDE, SURVIVAL, CANCER, REPAIR, PTEN, OLAPARIB

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/19019ac8-b570-49b4-9aac-6c318a149f4dTest

الإتاحة: https://doi.org/10.3390/biom11081188Test
https://hdl.handle.net/11370/19019ac8-b570-49b4-9aac-6c318a149f4dTest
https://research.rug.nl/en/publications/19019ac8-b570-49b4-9aac-6c318a149f4dTest
https://pure.rug.nl/ws/files/199262661/biomolecules_11_01188.pdfTest

المؤلفون: Cheng Wang (102692), Lailiang Qu (4447627), Shang Li (362882), Fucheng Yin (6430049), Limei Ji (9384155), Wan Peng (560398), Heng Luo (225807), Dehua Lu (10956301), Xingchen Liu (524190), Xinye Chen (7816226), Lingyi Kong (536841), Xiaobing Wang (305147)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, negative breast cancer, induce autophagy death, highly significant effects, growth inhibitory activities, good inhibitory effects, cause less damage, allowing targeted therapy, 5a , 50 , brca mutant cells, class dual parp, type brca cells, type brca, dual parp, tumor cells, normal cells, recent studies, promising compound, parp inhibitors

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_First-in-Class_Dual_PARP_and_EZH2_Inhibitors_for_Triple-Negative_Breast_Cancer_with_Wild-Type_BRCA/16530871Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c00567.s001Test

المؤلفون: Chubb, Jonathan Robert

مصطلحات موضوعية: 572.8, Migration, Mutant cells, Actin

الوصول الحر: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311944Test

المؤلفون: Tutt, A. N. J., Garber, J. E., Kaufman, B., Viale, G., Fumagalli, D., Rastogi, P., Gelber, R. D., de Azambuja, E., Fielding, A., Balmana, J., Domchek, S. M., Gelmon, K. A., Hollingsworth, S. J., Korde, L. A., Linderholm, Barbro, 1959, Bandos, H., Senkus, E., Suga, J. M., Shao, Z., Pippas, A. W., Nowecki, Z., Huzarski, T., Ganz, P. A., Lucas, P. C., Baker, N., Loibl, S., McConnell, R., Piccart, M., Schmutzler, R., Steger, G. G., Costantino, J. P., Arahmani, A., Wolmark, N., McFadden, E., Karantza, V., Lakhani, S. R., Yothers, G., Campbell, C., Geyer, C. E., Olympi, A. Clinical Trial Steering

المصدر: New England Journal of Medicine. 384:2394-2405

مصطلحات موضوعية: Clinical Medicine, Klinisk medicin, DNA-repair defect, mutant-cells, mutation, survival, pathology, ovarian, tumors, General & Internal Medicine

الوصول الحر: https://gup.ub.gu.se/publication/307007Test

المؤلفون: Min, Ahrum, Im, Seock-Ah, Kim, Debora Keunyoung, Song, Sang-Hyun, Kim, Hee-Jun, Lee, Kyung-Hun, Kim, Tae-Yong, Han, Sae-Won, Oh, Do-Youn, Kim, Tae-You, O'Connor, Mark J., Bang, Yung-Jue

المساهمون: 임석아, Im, Seock-Ah, Oh, Do-Youn, Kim, Tae-You, Bang, Yung-Jue

مصطلحات موضوعية: DNA-DAMAGE, POLY(ADP-RIBOSE) POLYMERASE, HOMOLOGOUS RECOMBINATION, MUTANT-CELLS, AUTOPHAGY, REPAIR, EXPRESSION, CHEMOTHERAPY, RESISTANCE, APOPTOSIS

العلاقة: Breast Cancer Research, Vol.17, p. 33; 59086; https://hdl.handle.net/10371/109894Test; 000369853400001; 2-s2.0-84928989870

الإتاحة: https://doi.org/10.1186/s13058-015-0534-yTest
https://hdl.handle.net/10371/109894Test

المؤلفون: Wadduwage, Dushan N., Kay, Jennifer, Singh, Vijay Raj, Kiraly, Orsolya, Sukup-Jackson, Michelle R., Rajapakse, Jagath, Engelward, Bevin P., So, Peter T. C.

المساهمون: School of Computer Science and Engineering, Singapore-MIT Alliance Programme

مصطلحات موضوعية: Homologous Recombination, Fluorescent Mutant Cells, DRNTU::Engineering::Computer science and engineering

وصف الملف: 11 p.; application/pdf

العلاقة: Scientific Reports; Wadduwage, D. N., Kay, J., Singh, V. R., Kiraly, O., Sukup-Jackson, M. R., Rajapakse, J., . . . So, P. T. C. (2018). Automated fluorescence intensity and gradient analysis enables detection of rare fluorescent mutant cells deep within the tissue of RaDR mice. Scientific Reports, 8(1), 12108-. doi:10.1038/s41598-018-30557-9; https://hdl.handle.net/10356/89695Test; http://hdl.handle.net/10220/46313Test

الإتاحة: https://doi.org/10.1038/s41598-018-30557-9Test
https://hdl.handle.net/10356/89695Test
http://hdl.handle.net/10220/46313Test

المؤلفون: Knijnenburg, TA, Wang, L, Zimmermann, MT, Chambwe, N, Gao, GF, Cherniack, AD, Fan, H, Shen, H, Way, GP, Greene, CS, Liu, Y, Akbani, R, Feng, B, Donehower, LA, Miller, C, Shen, Y, Karimi, M, Chen, H, Kim, P, Jia, P, Shinbrot, E, Zhang, S, Liu, J, Hu, H, Bailey, MH, Yau, C, Wolf, D, Zhao, Z, Weinstein, JN, Li, L, Ding, L, Mills, GB, Laird, PW, Wheeler, DA, Shmulevich, I, Monnat, RJ, Xiao, Y, Wang, C

المساهمون: SAIC-F-Frederick, Inc, Leidos Biomedical Research, Inc.

المصدر: 254 ; 239

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Cell Biology, REPLICATION FORK STABILITY, MICROSATELLITE INSTABILITY, PROMOTER HYPERMETHYLATION, POLYMERASE-EPSILON, PREDICTS RESPONSE, STRUCTURAL BASIS, MUTANT-CELLS, HUMAN COLON, MUTATIONS, INACTIVATION, DNA damage footprints, DNA damage repair, The Cancer Genome Atlas PanCanAtlas project, epigenetic silencing, integrative statistical analysis, mutational signatures, protein structure analysis, somatic copy-number alterations, somatic mutations, Cancer Genome Atlas Research Network

العلاقة: Cell Reports; http://hdl.handle.net/10044/1/71266Test; https://doi.org/10.1016/j.celrep.2018.03.076Test; TCGA Pilot Program; 15Y011ST

الإتاحة: https://doi.org/10.1016/j.celrep.2018.03.076Test
http://hdl.handle.net/10044/1/71266Test

المؤلفون: Branco, Rita, Morais, Paula V.

مصطلحات موضوعية: Superoxide dismutases, Reactive oxygen species, Chromate stress, Mutant cells, Fluorescent dyes, Bacterial Proteins, Chromates, Ochrobactrum, Superoxide Dismutase

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; PTDC/BIA-MIC/114958/2009; SFRH/BPD/48330/2008; http://hdl.handle.net/10316/108501Test

الإتاحة: https://doi.org/10.1186/s12866-016-0648-0Test
http://hdl.handle.net/10316/108501Test

المؤلفون: Swisher, EM, Lin, KK, Oza, AM, Scott, CL, Giordano, H, Sun, J, Konecny, GE, Coleman, RL, Tinker, AV, O'Malley, DM, Kristeleit, RS, Ma, L, Bell-McGuinn, KM, Brenton, JD, Cragun, JM, Oaknin, A, Ray-Coquard, I, Harrell, MI, Mann, E, Kaufmann, SH, Floquet, A, Leary, A, Harding, TC, Goble, S, Maloney, L, Isaacson, J, Allen, AR, Rolfe, L, Yelensky, R, Raponi, M, McNeish, IA

المصدر: 87 ; 75

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Oncology, HOMOLOGOUS RECOMBINATION DEFICIENCY, POLY(ADP-RIBOSE) POLYMERASE, GENOMIC LOSS, DNA-REPAIR, MUTANT-CELLS, CANCER, BREAST, HETEROZYGOSITY, OLAPARIB, TUMORS, Aged, Antineoplastic Agents, BRCA1 Protein, BRCA2 Protein, Carcinoma, Ovarian Epithelial, Drug Resistance, Neoplasm, Fallopian Tube Neoplasms, Female, Follow-Up Studies, Germ-Line Mutation, Humans, Indoles, International Agencies, Middle Aged, Neoplasm Recurrence

العلاقة: Lancet Oncology; http://hdl.handle.net/10044/1/54675Test

الإتاحة: https://doi.org/10.1016/s1470-2045Test(16)30559-9
http://hdl.handle.net/10044/1/54675Test

المصدر: Biomolecules. 11(8)

مصطلحات موضوعية: REPAIR, PTEN, MUTANT-CELLS, VELIPARIB ABT-888, glioblastoma, OLAPARIB, TEMOZOLOMIDE, DNA-DAMAGE RESPONSE, TUMORS, CANCER, PARP, BRCAness, SURVIVAL, PARP inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dris___01423::68ab137d4a42a3265bf002c81e00cbd2Test
https://research.rug.nl/en/publications/19019ac8-b570-49b4-9aac-6c318a149f4dTest