نتائج البحث - "MTT, 3-(4,5-dimethylthiazol-2-yl)− 2,5-diphenyltetrazolium bromide"

1

Figure 1. Effect of irrigating solutions on cell viability in a 2D culture.

مصطلحات موضوعية: Dental therapeutics, pharmacology and toxicology, irrigating solutions, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide)

العلاقة: https://figshare.com/articles/dataset/Figure_1_Effect_of_irrigating_solutions_on_cell_viability_in_a_2D_culture_/25385482Test

الإتاحة: https://doi.org/10.6084/m9.figshare.25385482.v1Test

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2

Selective BH3 mimetics synergize with BET inhibition to induce mitochondrial apoptosis in rhabdomyosarcoma cells

المؤلفون: Ufuk Erdogdu, Nadezda Dolgikh, Stephanie Laszig, Vinzenz Särchen, Michael T. Meister, Marek Wanior, Stefan Knapp, Cathinka Boedicker

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 109-119 (2022)
Neoplasia (New York, N.Y.)
Neoplasia

مصطلحات موضوعية: BH3 mimetics, PBMC, peripheral blood mononuclear cell, Cancer Research, chemical and pharmacologic phenomena, Antineoplastic Agents, Nerve Tissue Proteins, Receptors, Cell Surface, Apoptosis, PI, propidium iodide, BRD4, bromodomain-containing protein 4, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Biomimetics, hemic and lymphatic diseases, Cell Line, Tumor, Proto-Oncogene Proteins, Rhabdomyosarcoma, BRD, bromodomain, Humans, BET proteins, RC254-282, Original Research, EV, empty vector, zVAD.fmk, N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone, ATCC, American Type Culture Collection, mBCL-2, murine BCL-2, CI, combination index, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, hemic and immune systems, Drug Synergism, BET protein, Bromo- and Extra-Terminal protein, Peptide Fragments, Mitochondria, ERMS, embryonal rhabdomyosarcoma, ARMS, alveolar rhabdomyosarcoma, RMS, rhabdomyosarcoma, FCS, fetal calf serum, biological phenomena, cell phenomena, and immunity

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbac6aac81f4d40d574992bf92415f7Test
https://doi.org/10.1016/j.neo.2021.11.012Test

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TNFα Induces LGR5+ Stem Cell Dysfunction In Patients With Crohn’s Disease

المؤلفون: Chnasu Lee, Woong-Yang Park, Sung Noh Hong, Minae An, Je-Gun Joung, Dong Kyung Chang, Young-Ho Kim

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 789-808 (2022)

مصطلحات موضوعية: Tumor Necrosis Factor-Alpha, Prostaglandin E2, Cellular differentiation, Necroptosis, Population, PBS, phosphate-buffered saline, RC799-869, Biology, Receptors, G-Protein-Coupled, ER, endoplasmic reticulum, Intestinal Stem Cell, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Crohn Disease, DEG, differentially expressed gene, CD, Crohn’s disease, PGE2, prostaglandin E2, Humans, Viability assay, TUNEL, deoxyuride-5′-triphosphate biotin nick end labeling, Intestinal Mucosa, education, ANOVA, analysis of variance, NF-κB, nuclear factor kappa B, Original Research, scRNA-seq, single-cell RNA sequencing, TNF, tumor necrosis factor, education.field_of_study, Hepatology, CC3, cleaved caspase-3, Stem Cells, Intestinal Organoid, Gastroenterology, LGR5, Diseases of the digestive system. Gastroenterology, Intestinal epithelium, COX, cyclooxygenase, Organoids, ISC, intestinal stem cell, Cancer research, Tumor necrosis factor alpha, Stem cell, Crohn’s Disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1366d05d8f9fa7e6be064c7f2b8c07c9Test
https://doi.org/10.1016/j.jcmgh.2021.10.010Test

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Neomenthol prevents the proliferation of skin cancer cells by restraining tubulin polymerization and hyaluronidase activity

المؤلفون: Kaneez Fatima, Abha Meena, Suaib Luqman, Nusrat Masood, Zahoor Ahmad Wani

المصدر: Journal of Advanced Research

مصطلحات موضوعية: TRIG, Triglyceraldehyde, Skin Neoplasms, Cell, DOXO, Doxorubicin, Hyaluronidase, Pharmacology, NaOH, Sodium hydroxide, Polymerization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, BIL, Bilirubin total & direct, Neomenthol, PEP A, pepstatin A, Cancer biomarker, MEF, Mean erythrocyte fragility, HYAL, Hyaluronidase, PBS, Phosphate buffer saline, CM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetate, HA, Hyaluronic acid, Epidermoid carcinoma, Human epidermoid carcinoma, 030220 oncology & carcinogenesis, RBC, Red blood cell, DMEM, Dulbecco’s minimal essential media, SRB, Sulphorhodamine B, BUN, Blood urea nitrogen, FACS, Fluorescence-Activated Cell Sorting, AKLP, Alkaline phosphatase, Hyaluronoglucosaminidase, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, TMPD, N,N,N′,N′-tetramethyl-p-phenylenediamine, Article, 03 medical and health sciences, In vivo, Ehrlich Ascites Carcinoma, BE, Binding energy, Humans, CATD, Cathepsin D, LDH, Lactate dehydrogenase, COX-2, Cyclooxygenase 2, FOX, Ferrous oxidation-xylenol orange, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, In vitro, Ab/Am, Antibiotic/antimycotic, NRU, Neutral red uptake, EC50, Half maximal effective concentration, 030104 developmental biology, IC50, Half maximal inhibitory concentration, EAC, Ehlrich Ascites Carcinoma, RPMI, Roswell park memorial institute, ROS, Reactive oxygen species, 0301 basic medicine, HDL, High density lipoprotein, TNBS, Trinitrobenzenesulphonic acid, PI3K, Phosphotidyl inositol-3 kinase, URIC, Uric acid, DNA, Deoxyribonucleic acid, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid, Tubulin, OECD, Organization for Economic Co-operation and Development, SGPT, Alanine aminotransferase, LOX-5, Lipoxygenase-5, DFMO, α-difluoro methyl ornithine, Multidisciplinary, WBC, White blood cell, Chemistry, ELISA, enzyme-linked immunosorbent assay, PKB/Akt, Protein kinase B, AA, Arachidonic acid, RNase A, Ribonuclease A, TPR, Total protein, Molecular Docking Simulation, medicine.anatomical_structure, TCA, Tricarboxylic acid, CHOL, Cholesterol, Ki, Inhibitory constant, medicine.drug, ODC, Ornithine decarboxylase, DHFR, Dihydrofolatereductase, BSA, Bovine serum albumin, PDB, Protein Data Bank, medicine, Animals, MMP, Mitochondrial membrane potential, DCFDA, 2′,7′ dichloro fluorescin diacetate, RNA, Ribonucleic acid, RIPA, Radio immune precipitation assay buffer, EDTA, Ethylene diamine tetra acetic acid, IC50, TPA, 12-O-Tetradecanoylphorbol-13-acetate, ComputingMethodologies_COMPUTERGRAPHICS, TRPM8, Transient receptor potential member 8, Cell Proliferation, HDAC, Histone deacetylase, MTX, Methotrexate, OF, Osmotic fragility, PI, Propidium iodide, FDA, Food and Drug Administration, HEK293 Cells, PDT, Podophyllotoxin, Cell culture, NAC, N-acetyl cysteine, SGOT, Aspartate aminotransferase, CRTN, Creatinine, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, Rh123, Rhodamine 123, Ex vivo, IDT, Integrated DNA Technologies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618e7dc6e2d535e1930d5f8c2bf7d7eTest
https://doi.org/10.1016/j.jare.2021.06.003Test

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Gold nanorods-mediated efficient synergistic immunotherapy for detection and inhibition of postoperative tumor recurrence

المؤلفون: Hanjie Wang, Jin Chang, Kun Ge, Jinchao Zhang, Yu Tian, Chaonan Zhang, Wang Tiange, Yingying Zhang

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1978-1992 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: NIR, near-infrared irradiation, LLC, murine lung cancer cells, medicine.medical_treatment, anti-PDL1, anti-programmed cell death-ligand 1, HAuCl4, gold chloride, Metastasis, CdCl2, cadmium chloride, CdTe QDs, CdTe quantum dots, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, 0302 clinical medicine, Carcinoembryonic antigen, Fluorescence resonance energy transfer, DC, dendritic cells, GSH, glutathione, aPDL1-LA, anti-PDL1-modified liposomes encapsulated AuNRs, IFN-γ, interferon-γ, General Pharmacology, Toxicology and Pharmaceutics, Stage (cooking), Hydrogel+IFN-γ+QA, thermal responsive hydrogels co-loaded with AP1-QDs, PTT, photothermal therapy, DLS, dynamic light scattering, 0303 health sciences, aPDL1-LA+NIR, anti-PDL1-modified liposomes encapsulated AuNRs with near-infrared irradiation, NaBH4, sodium borohydride, biology, Late stage, TEM, transmission electron microscope, PD1, programmed cell death protein 1, CTCs, circulating tumor cells, NHS, N-hydroxysuccinimide, PLGA-PEG-PLGA, thermal responsive hydrogel, Tumor recurrence, Lung metastasis, 030220 oncology & carcinogenesis, Original Article, AP2-AuNRs, and interferon-γ, CD3, ICG, indocyanine green, AP2-AuNRs, CEA aptamer-modified AuNRs, aPDL1-LAI, anti-PDL1-modified liposomes loaded with ICG and encapsulated AuNRs, AP1-QDs, CEA aptamer-modified CdTe QDs, RM1-950, FRET, fluorescence resonance energy transfer, Synergistic immunotherapy, AFP, alpha fetoprotein, PI, propidium iodide, 03 medical and health sciences, FBS, fetal bovine serum, IR, infrared, NaHTe, sodium hydrogen telluride, medicine, AgNO3, silver nitrate, Post-surgical tumor recurrence, 030304 developmental biology, business.industry, QDs, quantum dots, Hydrogel+IFN-γ, thermal responsive hydrogels loaded with interferon-γ, Immunotherapy, LAI, liposomes loaded with ICG and encapsulated AuNRs, Photothermal therapy, Phototherapy, medicine.disease, Theranostics, Gold nanorods, EDC, 1-ethyl-3-(3′-dimethylaminopropyl) carbodiimide, CA, cancer antigen, Helf, human embryonic lung fibroblasts lines, LA, liposomes encapsulated AuNRs, PDL1, programmed cell death-ligand 1, biology.protein, Cancer research, CTAB, cetrimonium bromide, LA+NIR, liposomes encapsulated AuNRs with near-infrared irradiation, AuNRs, gold nanorods, Therapeutics. Pharmacology, CEA, carcinoembryonic antigen, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b427dfc66786d16834b8e45da6c2b16Test
http://www.sciencedirect.com/science/article/pii/S2211383521001076Test

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Phytomodulatory proteins isolated from Calotropis procera latex promote glycemic control by improving hepatic mitochondrial function in HepG2 cells

المؤلفون: Hygor N. Araujo, Ariclécio Cunha de Oliveira, Regina de Jesus das Neves, Tanes I. Lima, Renata Prado Vasconcelos, Paula Alexandre de Freitas, Keciany Alves de Oliveira, Marina Gabrielle Guimarães de Almeida, André Gustavo de Oliveira, Márcio V. Ramos, Leonardo R. Silveira, Bianca Cristine Favero-Santos, Dimitrius Santiago P.S.F. Guimarães

المصدر: Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 9, Pp 1061-1069 (2021)

مصطلحات موضوعية: Proteases, Latex, HGP, Hepatic glucose production, Pharmaceutical Science, RM1-950, Pharmacology, PPAR, Peroxisome proliferator-activated receptor, UCP2, Mitochondrial uncoupling protein 2, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, FCCP, Oligomycin carbonyl cyanide 4 (trifluoromethoxy) phenylhydrazine, Calotropis procera, Bioactive proteins, Gene expression, Viability assay, PPRE, PPAR response element, Protein kinase A, Glycemic, chemistry.chemical_classification, Reactive oxygen species, CpPII, Major peptidase fraction treated with iodoacetamide, biology, Chemistry, AMPK, AMP-activated kinase protein, AMPK, DMEM, Dulbecco’s minimal essential medium, DMSO, Dimethyl sulfoxide, DHE, Dihydroethidium, OXPHOS, Oxidative phosphorylation, TBS-T, Tris buffered saline solution containing 0.1% Tween 20, biology.organism_classification, AUC, Area under the curve, Folk medicine, OCR, Oxygen consumption rate, CTL, Control, Original Article, Therapeutics. Pharmacology, Glycemia, LP, Soluble latex proteins from Calotropis procera, ROS, Reactive oxygen species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b5f0bac9dfc1fd17b68bf7d99c68aTest
http://europepmc.org/articles/PMC8463474Test

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From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution

المؤلفون: Antonietta Rossi, Tran Hung, Oliver Werz, Christina Weinigel, Rossella Bilancia, Birgit Waltenberger, Zhigang Rao, Veronika Temml, Hermann Stuppner, Christian Kretzer, Carsten Giesel, Andreas Koeberle, Stefan Schwaiger, Silke Rummler, Alilou Mostafa, Tran Thi Van Anh, Paul M. Jordan, Simona Pace

المساهمون: Van Anh, T. T., Mostafa, A., Rao, Z., Pace, S., Schwaiger, S., Kretzer, C., Temml, V., Giesel, C., Jordan, P. M., Bilancia, R., Weinigel, C., Rummler, S., Waltenberger, B., Hung, T., Rossi, A., Stuppner, H., Werz, O., Koeberle, A.

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1629-1647 (2021)

مصطلحات موضوعية: 12-HHT, 12(S)-hydroxy-5-cis-8,10-trans-heptadecatrienoic acid, Lipoxygenase, UPLC‒MS/MS, ultra-performance liquid chromatography–tandem mass spectrometry, chemistry.chemical_compound, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, 0302 clinical medicine, RP, reversed phase, mPGES-1, microsomal prostaglandin E2 synthase 1, General Pharmacology, Toxicology and Pharmaceutics, Prostaglandin E2, LOX, lipoxygenase, chemistry.chemical_classification, DPPH, 2,2-diphenyl-1-picrylhydrazyl, 0303 health sciences, biology, ESI, electrospray ionization, Rv, resolvin, Biflavonoid, SPM, specialized pro-resolving mediators, PMNL, polymorphonuclear neutrophils, Cell biology, MaR, maresin, PBMC, peripheral blood mononuclear cells, SPE, solid phase extraction, Lipid mediator, HPLC, high performance liquid chromatography, PD, protectin, 030220 oncology & carcinogenesis, Original Article, medicine.symptom, medicine.drug, DAD, diode array detector, Leukotriene Production, Allosteric regulation, LT, leukotriene, Inflammation, RM1-950, Natural product, 03 medical and health sciences, Biosynthesis, ECD, electronic circular dichroism, LTC4S, leukotriene C4 synthase, medicine, IFN, interferon, PG, prostaglandin, 030304 developmental biology, Lipidomic, TX, thromboxane, 5-H(p)ETE, 5-hydro(pero)xy-eicosatetraenoic acid, Lipid signaling, HR, high resolution, sEH, soluble epoxide hydrolase, IL, interleukin, COX, cyclooxygenase, chemistry, Lipidomics, biology.protein, Therapeutics. Pharmacology, FCS, fetal calf serum, Resolution