المؤلفون: Ying Han, Xintong Zhang, Wei Huang, Zhonggao Gao, Mingji Jin

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1789-1812 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: SLC, solute carrier, Bioavailability, AMI, amiodarone, MPA, mycophenolic acid, TLCA, taurolithocholate, ASP, amisulpride, RA, rheumatoid arthritis, Review, NRs, nitroreductases, MDR1, multidrug resistance gene 1, NaGC, sodium glycholate, MATEs, multidrug and toxin extrusion proteins, NMEs, new molecular entities, 0302 clinical medicine, HFD, high fat diet, P-gp, P-glycoprotein, ACS, amphipathic chitosan derivative, Medicine, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, 0303 health sciences, Gastrointestinal tract, IBD, inflammatory bowel disease, pKa, dissociation constant, RBC, red blood cell, FA, folate, OATs, organic anion transporters, 030220 oncology & carcinogenesis, MKC, monoketocholic acid, the GI tract, the gastrointestinal tract, AQP4, aquaporin 4, OCTNs, organic zwitterion/cation, T2D, type 2 diabetes, Gut microbiota, RM1-950, WHO, World Health Organization, 03 medical and health sciences, EcN, Escherichia coli Nissle 1917, Drug Transport Process, BDEPT, the bacteria-directed enzyme prodrug therapy, BCS, biopharmaceutics classification system, NEC, necrotizing enterocolitis, DRPs, digoxin reduction products, NaDC, sodium deoxycholate, Probiotics, CPP, cell-penetrating peptide, OCTs, organic cation transporters, TDCA, taurodeoxycholate, cgr operon, cardiac glycoside reductase operon, RA - Rheumatoid arthritis, DCA, deoxycholic acid, AA, ascorbic acid, BBR, berberine, Personalized medicine, BDDCS, the biopharmaceutics drug disposition classification system, SSZ, sulfasalazine, UDC, ursodeoxycholic acid, PPIs, proton pump inhibitors, BCRP, breast cancer resistance protein, CS, chitosan, Gut flora, Bioinformatics, PD, Parkinson's disease, SLN, solid lipid nanoparticle, SGLT-1, sodium-coupled glucose transporter 1, Oral administration, MRP2, multidrug resistance-associated protein 2, FAO, Food and Agriculture Organization of the United Nations, SVCT-1/2, the sodium-dependent vitamin C transporter-1/2, an OTC drug, an over-the-counter drug, CA, cholic acid, biology, ABC, ATP-binding cassette, T1DM, type 1 diabetes mellitus, NSAIDs, non-steroidal anti-inflammatory drugs, AR, azoreductase, GCDC, glycochenodeoxycholate, Drug delivery, GL, glycyrrhizic acid, PT, pectin, LPS, lipopolysaccharide, TME, the tumor microenvironment, T1D, type 1 diabetes, TCDC, taurochenodeoxycholate, Oral drugs, MDR1a, multidrug resistance protein-1a, SCFAs, short-chain fatty acids, CDCA, chenodeoxycholic acid, 030304 developmental biology, business.industry, dhBBR, dihydroberberine, biology.organism_classification, HTC, hematocrit, PWSDs, poorly water-soluble drugs, Colon-specific drug delivery system, stomatognathic diseases, SP, sulfapyridine, 5-ASA, 5-aminosalicylic acid, BSH, bile salt hydrolase, TCA, taurocholate, Therapeutics. Pharmacology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d001e27a816f9de7d75ff16dd2143ecTest
http://www.sciencedirect.com/science/article/pii/S2211383520307279Test

المؤلفون: Pani, Arianna, Cento, Valeria, Vismara, Chiara, Campisi, Daniela, Di Ruscio, Federica, Romandini, Alessandra, Senatore, Michele, Schenardi, Paolo Andrea, Gagliardi, Oscar Matteo, Giroldi, Simona, Zoppini, Laura, Moreno, Mauro, Corradin, Matteo, Epis, Oscar Massimiliano, Ughi, Nicola, Cuppari, Irene, Crocchiolo, Roberto, Merli, Marco, Bosio, Marco, Rossini, Silvano, Puoti, Massimo, Scaglione, Francesco

المصدر: Mayo Clinic Proceedings

مصطلحات موضوعية: CI, confidence interval, RT-PCR, reverse transcription polymerase chain reaction, VOC, variant of concern, BMI, body mass index, BAU, binding arbitrary units, MPA, mycophenolic acid, MPPDH, inosine-5’-monophosphate dehydrogenase, Original Article, MMF, mycophenolate mofetil, IQR, interquartile range

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmc_________::19afe00f5b79b92164a3c423d31c8d90Test
http://europepmc.org/articles/PMC8403667Test

المؤلفون: Kumar Sharma, Annapurna Pamreddy, Amrita Basu, Pragya Singh

المصدر: Journal of Molecular Biology

مصطلحات موضوعية: ALP, Alkaline phosphatase, MERS, Middle East Respiratory Syndrome, Future application, Review Article, AOP, Adverse Outcome Pathway, Disease, hrsACE2, human recombinant soluble angiotensin-converting enzyme 2, Bioinformatics, CLD, Chronic Liver Disease, angiotensin-converting enzyme 2 (ACE2), Structural Biology, Adverse Outcome Pathway, hiPSCs, human induced Pluripotent Stem cells, QNHC, Quinacrine dihydrochloride, COVID-19, Coronavirus disease 2019, ARDS, Acute Respiratory Distress Syndrome, Adverse Outcome Pathway (AOP), GFP, Green fluorescent Protein, IFN, Interferon, Organoids, Angiotensin-Converting Enzyme 2, AST, Aspartate aminotransferase, 2D, 2-Dimensional, hESC, Human Embryonic Stem Cell, Coronavirus disease 2019 (COVID-19), Adverse outcomes, Multiple Organ Failure, ALI, Air-Liquid Interface, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), TNF-a, Tumor Necrosis Factor- a, Biology, ACE2, angiotensin-converting enzyme 2, Models, Biological, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Organoid, Humans, Molecular Biology, 3D, 3-Dimensional, LDH, Lactate Dehydrogenase, SARS-CoV-2, Liver and kidney, IL-6, Interleukin 6, ALT, Alanine aminotransferase, COVID-19, Kidney 3D Organoids, Lung 3D Organoids, Liver 3D Organoids, ESC, Embryonic stem cells, AT2, Alveolar Type-2, TMPRSS2, transmembrane serine protease 2, SARS-CoV, Severe Acute Respiratoy Syndrome, MPA, Mycophenolic Acid, ANG II, Angiotensin II, CKD, Chronic Kidney Disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62501267315c032bde4f6084ae3c96d3Test
https://doi.org/10.1016/j.jmb.2021.167213Test

المؤلفون: Chayanee Setthapramote, Peter J. Bredenbeek, Jordan J. Clark, Alain Kohl, Ricardo Sanchez-Velazquez, Arvind H. Patel, Margus Varjak, Margaret R. MacDonald, Charles M. Rice, Leonia Bozzacco, Rapeepat Tandavanitj, Giuditta De Lorenzo

المصدر: Antiviral Research
Antiviral Research, 183. ELSEVIER

مصطلحات موضوعية: 0301 basic medicine, viruses, 030106 microbiology, LgBiT, large NanoBiT subunit, Biology, Immune sera, Virus Replication, Antiviral Agents, Virus, scFv, single chain variable fragments, Cell Line, 03 medical and health sciences, Flaviviridae, Mice, CPER, Genes, Reporter, Drug screen, Virology, Drug Discovery, medicine, Animals, Humans, Luciferase, NanoBiT, NanoLuc binary technology, Polymerase, PRNT, plaque reduction neutralization test, Pharmacology, Mice, Inbred BALB C, MPA, Mycophenolic acid, sE, soluble E protein, TB, test bleed, Yellow fever, medicine.disease, biology.organism_classification, Reverse genetics, Reverse Genetics, High-Throughput Screening Assays, 030104 developmental biology, Viral replication, YFV, yellow fever virus, pA, SV40 polyadenylation signal, HDVr, hepatitis delta virus ribozyme, HiBiT, biology.protein, Yellow fever virus, CPER, circular polymerase extension reaction, Research Paper

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2fada7cc6855938f6b1182f2a75b1ffTest
https://hdl.handle.net/1887/3185087Test

المؤلفون: Zichen, Zhang, Yi, Lu, Jianping, Qi, Wei, Wu

المصدر: Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Oral, RGD, Arg-Gly-Asp, Microfold cell, RGDp, RGD peptidomimetic, MPA, mycophenolic acid, WGA, wheat germ agglutinin, PLGA, poly(lactic-co-glycolic acid), SLN, solid lipid nanoparticles, Review, DTX, docetaxel, AUC, area under curve, FAE, follicle-associated epithelia, Chylomicron, PVA, poly(vinyl alcohol), Lymphatic transport, ASRT, apical sodium-dependent bile acid transporter, DC, dendritic cell, LDL, low-density lipoprotein, DDT, dichlorodiphenyltrichloroethane, LDVp, LDV peptidomimetic, SEDDS, self-emulsifying drug delivery system, TEM, transmission electron microscopy, Drug absorption, ACQ, aggregation-caused quenching, MPS, mononuclear phagocyte system, BCS, biopharmaceutics classification system, PEI, polyethyleneimine, TU, testosterone undecanoate, TPGS, D-α-tocopherol polyethylene glycol 1000 succinate, FRET, Föster resonance energy transfer, TG, triglyceride, YCW, yeast cell wall, FA, fatty acid, GIT, gastrointestinal tract, SNEDDS, self-nanoemulsifying drug delivery system, Drug carriers, LDV, Leu-Asp-Val, PCL, polycaprolactone, CM, chylomicron, HIV, human immunodeficiency virus, HBsAg, hepatitis B surface antigen, MG, monoglyceride, OA, oleate, Drug delivery, M cell, microfold cells, Nanoparticles, PEG-PLA, polyethylene glycol-poly(lactic acid)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::b6cb3989e31e5b607031720a5e2a906bTest
https://pubmed.ncbi.nlm.nih.gov/34522594Test

المؤلفون: Yau-Hung Chen, Chih Hua Hsieh, Shu Chun Cheng, Min Han Lin, Chi-Yuan Chou, David C. Moses, Chiao Yin Sun

المصدر: Antiviral Research

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, viruses, CoV, coronavirus, MPA, mycophenolic acid, Molecular Conformation, medicine.disease_cause, 0302 clinical medicine, Case fatality rate, MERS- and SARS-CoV, Disulfiram, βME, β-mercaptoethanol, DUB, deubiquitination, Synergistic inhibition, media_common, PLpro, papain-like protease, DDC, diethyldithiolcarbamate, virus diseases, 6-Thioguanine, respiratory system, Severe acute respiratory syndrome-related coronavirus, 030220 oncology & carcinogenesis, Middle East Respiratory Syndrome Coronavirus, medicine.drug, Protein Binding, Drug, Proteases, Middle East respiratory syndrome coronavirus, media_common.quotation_subject, Allosteric regulation, Microbial Sensitivity Tests, Antiviral Agents, Article, 03 medical and health sciences, Enzyme activator, Inhibitory Concentration 50, Virology, medicine, Humans, Mycophenolic acid, nsp, non-structural protein, SARS, severe acute respiratory syndrome, Pharmacology, Dose-Response Relationship, Drug, business.industry, MERS, Middle East respiratory syndrome, Outbreak, biochemical phenomena, metabolism, and nutrition, respiratory tract diseases, Papain-like protease, Enzyme Activation, Mpro, main protease, 030104 developmental biology, NEM, N-ethylmaleimide, business, Peptide Hydrolases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b6662e0a8bb192f6a149bdf79f9f28Test
http://europepmc.org/articles/PMC7113793Test

المؤلفون: Masanori Ikeda, Nobuyuki Kato

المصدر: Advanced Drug Delivery Reviews

مصطلحات موضوعية: Hepacivirus, MPA, mycophenolic acid, effective concentration to inhibit HCV RNA replication, CMV, cytomegarovirus, AA, arachidonic acid, PTB, polypyrimidine tract-binding protein, FPP, farnesyl pyrophosphate, GTP, guanosine triphosphate, Replicon, Enzyme Inhibitors, HMG–CoA, 3-hydroxy-3-methylglutaryl coenzyme A, virus diseases, Interferon, La, La auto antigen, PTV, pitavastatin, HSP90, heat shock protein 90, uPA-SCID, urokinase plasminogen activator-severe combined immunodeficiency, Host metabolism, Antiviral Agents, Article, monophosphate, ORF, open reading frame, FLV, fluvastatin, EC50, 50%, Humans, SARS, severe acute respiratory syndrome, Antiviral, LFA-1, lymphocyte function associated antigen-1, GGTase-I, geranylgeranyltransferase type I, AdoMet, S-adenosyl-L-methionine, EMCV, encephalomyocarditis virus, Lipid Metabolism, Virology, SPT, serine palmitoyltransferase, digestive system diseases, PIAS1, protein inhibitor of activated STAT1, Internal ribosome entry site, chemistry, Immunology, ICAM-1, integrin intercellular adhesion molecule 1, RSV, respiratory syncytial virus, SMV, simvastatin, LOV, lovastatin, PRMT1, protein arginine methyltransferase 1, FTase, farnesyltransferase, RTP, ribavirin triphosphate, Drug Evaluation, Preclinical, Pharmaceutical Science, DHA, docosahexaenoic acid, medicine.disease_cause, Virus Replication, chemistry.chemical_compound, biology, IMPDH, inosine monophosphate dehydrogenase, Hepatitis C virus, Hepatitis C, PEG-IFN, pegylated-IFN, PRV, pravastatin, HIV, human immunodeficiency virus, CH, chronic hepatitis, IRES, internal ribosome entry site, HCV, hepatitis C virus, SBD, sphingolipid-binding domain, FKBP8, FK-506-binding protein 8, Neo, neomycin phosphotransferase, medicine.drug, GSL, glycosphingolipid, GBV-B, GB virus B, GGTI, GGTase-I inhibitor, Models, Biological, Virus, GGPP, geranylgeranyl pyrophosphate, CyPB, cyclophilin B, CsA, cyclosporine+ A, ER, endoplasmic reticulum, Flaviviridae, RdRp, RNA dependent RNA polymerase, ALT, alanine aminotransferase, medicine, Animals, IFN, interferon, SVR, sustained virological response, DRM, detergent resistant membrane, GLA, γ-linolenic acid, XMP, xanthosine 5′, NS, nonstructural, Ribavirin, PUFAs, polyunsaturated fatty acids, Statin, biology.organism_classification, EPA, eicosapentaenoic acid, ATV, atorvastatin, HBV, hepatitis B virus, RMP, ribavirin monophosphate, PP2Ac, catalytic subunit of protein phosphatase 2A, VLP, virus-like particle, RDP, ribavirin diphosphate, HCC, hepatocellular carcinoma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381ce6f5ffe8da770afa3197205b9719Test
http://europepmc.org/articles/PMC7103349Test

المؤلفون: Jonsson, Colleen B., Chang, Dong H.

المساهمون: SOUTHERN RESEARCH INST BIRMINGHAM AL

المصدر: DTIC

مصطلحات موضوعية: Medicine and Medical Research, Pharmacology, ANTIVIRAL AGENTS, ENCEPHALITIS, TOXICITY, GRAPHS, SIGNAL TO NOISE RATIO, PLASMIDS, DOSAGE, TABLES(DATA), CYTOTOXINS, CELLS(BIOLOGY), ASSAYING, ARBOVIRUSES, VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS, LUCIFERASE, DENSITY, VALIDATION, HTS(HIGH THROUGHPUT SCREEN), LUCIFERASE TAGGED VEEV, CELL DENSITY, DMSO(DIMETHYLSULPHOXIDE), Z FACTOR, ASSAY ROBUSTNESS, COMPOUND DIVERSITY LIBRARIES, CYTOTOXICITY, MPA(MYCOPHENOLIC ACID), VEEV(VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS)

وصف الملف: text/html

العلاقة: http://www.dtic.mil/docs/citations/ADA540027Test

الإتاحة: http://www.dtic.mil/docs/citations/ADA540027Test
http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA540027Test

المصدر: DTIC

مصطلحات الفهرس: Medicine and Medical Research, Pharmacology, ANTIVIRAL AGENTS, ENCEPHALITIS, TOXICITY, GRAPHS, SIGNAL TO NOISE RATIO, PLASMIDS, DOSAGE, TABLES(DATA), CYTOTOXINS, CELLS(BIOLOGY), ASSAYING, ARBOVIRUSES, VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS, LUCIFERASE, DENSITY, VALIDATION, HTS(HIGH THROUGHPUT SCREEN), LUCIFERASE TAGGED VEEV, CELL DENSITY, DMSO(DIMETHYLSULPHOXIDE), Z FACTOR, ASSAY ROBUSTNESS, COMPOUND DIVERSITY LIBRARIES, CYTOTOXICITY, MPA(MYCOPHENOLIC ACID), VEEV(VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS), Text

URL: https://apps.dtic.mil/docs/citations/ADA540027Test