المؤلفون: Yuri Bolshan, Rima Al-awar, Aiping Dong, Gregory A. Wasney, Hao He, Alma Seitova, Irene Chau, Ludmila Dombrovski, Taraneh Hajian, Hong Wu, Dalia Barsyte-Lovejoy, Fengling Li, Gennadiy Poda, Kong T. Nguyen, Cheryl H. Arrowsmith, Jean-François Couture, Guillermo Senisterra, David Smil, Matthieu Schapira, Masoud Vedadi, Peter Brown, Abdellah Allali-Hassani

المصدر: Biochemical Journal

مصطلحات موضوعية: PTM, post-translational modification, Multiprotein complex, Methyltransferase, mixed-lineage leukemia protein (MLL), WDR5, WD40 repeat protein 5, HDAC, histone deacetylase, MLL, mixed-lineage leukaemia protein, Crystallography, X-Ray, DSF, differential scanning fluorimetry, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, WD40 repeat, Catalytic Domain, hemic and lymphatic diseases, PEG, poly(ethylene glycol), Humans, ASH2L, absent small homoeotic discs-2-like, WDR5, Protein Interaction Domains and Motifs, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, AFF, AF4/FMR2 family protein, biology, ITC, isothermal titration calorimetry, histone methyltransferase, RbBP5, retinoblastoma-binding protein 5, Intracellular Signaling Peptides and Proteins, SET1, Su(var)3–9 enhancer-of-zeste trithorax 1, Histone-Lysine N-Methyltransferase, Cell Biology, Small molecule, Enzyme, Histone, chemistry, Ni-NTA, Ni2+-nitrilotriacetate, 030220 oncology & carcinogenesis, leukaemia, biology.protein, H3K4me3, WD40 repeat protein 5 (WDR5), HMT, histone methyltransferase, WIN, WDR5-interacting, Myeloid-Lymphoid Leukemia Protein, Protein Binding, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cb0e782cada5d2aca26938e6c680b2Test
https://doi.org/10.1042/bj20121280Test

المؤلفون: Robert J. Klose, Neil P. Blackledge, Hannah K. Long

المصدر: Long, H K, Blackledge, N P & Klose, R J 2013, ' ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection ', Biochemical Society Transactions, vol. 41, no. 3, pp. 727-40 . https://doi.org/10.1042/BST20130028Test
Biochemical Society Transactions

مصطلحات موضوعية: 5mC, 5-methylcytosine, Models, Molecular, ESC, embryonic stem cell, AF9, ALL1–fused gene from chromosome 9 protein, DPY-30, dosage compensation protein 30, FBXL19, F-box and leucine-rich repeat protein 19, HDAC, histone deacetylase, TET, ten-eleven translocation, Biochemical Society Annual Symposium No. 80, Biochemistry, PHD, plant homeodomain, MLL, mixed lineage leukaemia protein, 0302 clinical medicine, DNA/metabolism, MBD, methyl-CpG-binding domain, RFTS, replication foci-targeting sequence, 5hmC, 5-hydroxymethylcytosine, Epigenomics, Genetics, 0303 health sciences, DNA methylation, KDM, lysine demethylase, RbBP5, retinoblastoma-binding protein 5, YY1, Yin and Yang 1, SEC, super-elongation complex, Zinc Fingers, Protein Binding/physiology, Chromatin, CpG Islands/genetics, DNA-Binding Proteins, CFP1, CxxC finger protein 1, CpG site, DNA demethylation, shRNA, short hairpin RNA, CGI, CpG island, CGBP, CpG-binding protein, transcription, ChIP-seq, chromatin immunoprecipitation sequencing, BAH, bromo-adjacent homology, Protein Binding, DNA Methylation/genetics, DNA-Binding Proteins/chemistry, WDR, WD40 repeat, S1, HMG-box, Molecular Sequence Data, S7, ZF-CxxC, zinc finger-CxxC, Biology, RING, really interesting new gene, Chromatin/metabolism, Protein Structure, Tertiary/genetics, ENL, eleven-nineteen leukaemia, 03 medical and health sciences, IDAX, inhibition of the Dvl and axin complex protein, Epigenetics of physical exercise, DNMT1, DNA methyltransferase 1, Humans, Amino Acid Sequence, 030304 developmental biology, JmjC, Jumonji C, Zinc Fingers/genetics, epigenetics, ASH2L, absent, small or homeotic 2-like, RNAPII, RNA polymerase II, DNA, PRC, polycomb group repressive complex, Protein Structure, Tertiary, Methyl-CpG-binding domain, SETD1, SET domain 1, Differentially methylated regions, CpG island, CpG Islands, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d23e5886961723d395fb4798c63f76Test
https://ora.ox.ac.uk/objects/uuid:194ec326-8549-4a6f-a9fd-66f9001fc79cTest

المؤلفون: Francesco Salvatore, Gabriella Esposito, Francesca De Falco, Armando Cevenini, Alessandro Cuomo, Fabrizio Pane, Margherita Ruoppolo, Dario Sabbatino

المساهمون: Esposito, Gabriella, Cevenini, Armando, Cuomo, Alessandro, DE FALCO, F., Sabbatino, D., Pane, Fabrizio, Ruoppolo, Margherita, Salvatore, Francesco

المصدر: Biochemical Journal

مصطلحات موضوعية: MLL, mixed-lineage leukaemia, Proteomics, MED, Mediator complex subunit, acute lymphoblastic leukaemia, Transcription, Genetic, FMR2, Fragile X E mental retardation syndrome, SEC, super elongation complex, AEP complex, AF4–ENL–P-TEFb complex, RNA polymerase II, ECL, enhanced chemiluminescence, Kidney, mixed-lineage leukaemia chimaera (MLL chimaera), Biochemistry, Chromatography, Affinity, EAF1, ELL-associated factor 1, ELL, eleven-nineteen lysine-rich leukaemia, Transcription (biology), MS/MS, tandem MS, Protein Interaction Mapping, Electrophoresis, Gel, Two-Dimensional, Gene Regulatory Networks, Mediator complex, Phosphorylation, Cells, Cultured, Genetics, LAF4, lymphoid nuclear protein related to AF4, biology, Nuclear Proteins, HOXA9, homeobox A9, WCE, whole cell extract, CTD, C-terminal domain, DNA-Binding Proteins, PICM, protease inhibitor cocktail for mammalian tissues, RNA polymerase II-mediated transcription elongation, Transcriptional Elongation Factors, aa, amino acids, Research Article, AF4 interactome, P-TEFb, positive transcription elongation factor b, HPRD, Human Protein Reference Database, Multiprotein complex, Blotting, Western, Molecular Sequence Data, Protein–protein interaction, HEK, human embryonic kidney, Mediator, FBS, fetal bovine serum, MCM, minichromosome maintenance, Humans, Immunoprecipitation, CDK9, cyclin-dependent kinase 9, Amino Acid Sequence, Molecular Biology, Gene, SIAH, seven in absentia homologue, Pol II, RNA polymerase II, ALF, AF4/LAF4 (Lymphoid nuclear protein related to AF4)/FMR2 (Fragile X E mental retardation syndrome), DNA Polymerase II, Cell Biology, protein—protein interaction, AF4–ENL–P-TEFb complex (AEP complex), bp, base pairs, protein–protein interaction, Gene Expression Regulation, LC-ESI, liquid chromatography-electrospray ionization, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, biology.protein, Cyclin-dependent kinase 9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91901eb92bec35693ec7c608ca9e749fTest
https://doi.org/10.1042/bj20101633Test

المؤلفون: Li‑Chao Fang, Jun Deng, Junsong Zheng, Jie Yao, Zai‑Lin Yang, Hui Huang, Yan Li

المصدر: Bioscience Reports, Vol 34, Iss 6, p e00156 (2014)
Bioscience Reports

مصطلحات موضوعية: lcsh:Life, lcsh:QR1-502, Apoptosis, Biochemistry, lcsh:Microbiology, Histones, AML, Gene Knockdown Techniques, Promoter Regions, Genetic, Gene knockdown, MSP, methylation-specific PCR, Estradiol, Gene Expression Regulation, Leukemic, Reverse Transcriptase Polymerase Chain Reaction, ALL, acute lymphoblastic leukaemia, Methylation, HOXA10, MLL, mixed lineage leukaemia histone methylase, oestrogen receptor, ChIP, chromatin immunoprecipitation, Histone, Leukemia, Myeloid, Acute Disease, Myeloid-Lymphoid Leukemia Protein, AML, acute myeloid leukaemia, Protein Binding, Expression of Concern, ER, oestrogen receptor, mixed lineage leukaemia, Blotting, Western, Biophysics, HL-60 Cells, Biology, Response Elements, S2, Cell Line, Tumor, Estrogen Receptor beta, Humans, Epigenetics, ERE, oestrogen response element, Molecular Biology, Estrogen receptor beta, Homeodomain Proteins, Original Paper, NP40, Nonidet P40, Lysine, Estrogen Receptor alpha, LSD1, lysine-specific demethylase 1, Estrogens, Cell Biology, Histone-Lysine N-Methyltransferase, lcsh:QH501-531, H3K4, H3 at lysine 4, Homeobox A10 Proteins, Cancer research, biology.protein, HMT, histone methyltransferase, gene regulation, Estrogen receptor alpha

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5647f026d858cf818bf65ebaaed6d196Test
http://www.bioscirep.org/bsr/034/e156/bsr034e156.htmTest

المؤلفون: Sergio Verjovski-Almeida, Carlos DeOcesano-Pereira, Felipe Beckedorff, Murilo S. Amaral

المصدر: Bioscience Reports, Vol 33, Iss 4, p e00061 (2013)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Bioscience Reports

مصطلحات موضوعية: MLL, mixed-lineage leukaemia, HDM, histone demethylase, lcsh:Life, lcsh:QR1-502, Gene Expression, SMARCA2, SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, type 2 (also known as BRM), HDAC, histone deacetylase, LSD1, lysine (K)-specific demethylase 1A, Review Article, medicine.disease_cause, Biochemistry, lcsh:Microbiology, Epigenesis, Genetic, Histones, CpG, cytosine phosphodiester bond guanine, lncRNA, long non-coding RNA, HOX, homeobox, long non-coding RNAs, Neoplasms, CTBP1-AS, C-terminal binding protein 1 antisense, PSF, phosphotyrosine-binding-associated splicing factor, Cancer epigenetics, CHD, chromodomain helicase DNA-binding protein, H3K27me3, histone 3 lysine 27 trymethylated, INK4b, inhibitor of cyclin-dependent kinase 4b, ARF, ADP-ribosylation factor, ANRASSF1, antisense non-coding RNA in the RASSF1A locus, Epigenesis, Regulation of gene expression, Genetics, EZH2, enhancer of zeste homologue 2, intergenic lncRNA, lincRNA, long intergenic non-coding RNA, ANRIL, antisense non-coding RNA in the INK4 locus, Nucleosomes, Gene Expression Regulation, Neoplastic, CRC, colorectal cancer, DNA methylation, RNA, Long Noncoding, S1, PCAT-1, prostate cancer-associated ncRNA transcript 1, Biophysics, Biology, regulatory RNA, RNA-guided gene silencing, INK4a, inhibitor of cyclin-dependent kinase 4a, XCI, X chromosome inactivation, medicine, Animals, Humans, Epigenetics, LICR, Ludwig Institute for Cancer Research, Molecular Biology, Gene, RNAPII, RNA polymerase II, Cancer, RASSF1A, Ras association (RalGDS/AF-6) domain family member 1 isoform A, Cell Biology, DNA Methylation, medicine.disease, cancer epigenetics, lcsh:QH501-531, XIST, X-inactive specific transcript, RNA, AR, androgen receptor, PRC, polycomb repressive complex, HMT, histone methyltransferase, HOTAIR, homeobox antisense intergenic RNA, Carcinogenesis, intronic lncRNA, Protein Processing, Post-Translational

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac8c7f2e713646aa0543a01e0419d3bTest
http://www.bioscirep.org/bsr/033/e061/bsr033e061.htmTest