المؤلفون: Ruoxi Zhang, Rui Kang, Daolin Tang

المصدر: Chinese Journal of Traumatology
Chinese Journal of Traumatology, Vol 25, Iss 1, Pp 1-10 (2022)

مصطلحات موضوعية: Medicine (General), type I IFNs, type I interferons, Review Article, PLCG1, phospholipase C gamma 1, CGAS, cyclic GMP-AMP synthase, Orthopedics and Sports Medicine, MLKL, mixed-lineage kinase domain-like pseudokinase, SQSTM1, sequestosome 1, ALK, ALK receptor tyrosine kinase, caspase, CASP, Shock, Septic, AKT, serine-threonine kinase, DMXAA, 5,6-dimethylxanthenone-4-acetic acid, TNFα, tumor necrosis factor α, CLP, cecal ligation and puncture, GPX4, glutathione peroxidase 4, medicine.symptom, HMGB1, high-mobility group box 1, Cell death, Programmed cell death, AIM2, absent in melanoma 2, Multiple Organ Failure, NF-κB, nuclear factor-κB, RIPK, receptor interacting serine/threonine-protein kinase, Inflammation, CDNs, cyclic dinucleotides, CXCL10, C-X-C motif chemokine ligand 10, CCL2, C-C motif chemokine ligand 2, Sepsis, ER, endoplasmic reticulum, R5-920, Immune system, Immunity, PAMPs, pathogen-associated molecular patterns, medicine, Autophagy, Humans, GSDMD, gasdermin D, PRRs, pattern-recognizing receptors, TLR9, toll-like receptor 9, Innate immune system, STING1, Septic shock, business.industry, IRF3, interferon regulatory factor 3, cfDNA, cell-free DNA, STING1, stimulator of interferon response cGAMP interactor 1, medicine.disease, Immunity, Innate, mtDNA, mitochondrial DNA, EGFR, epidermal growth factor receptor, IFNAR1, interferon alpha and beta receptor subunit 1, IL, interleukin, Immunology, DAMPs, damage-associated molecular patterns, TBK1, TANK-binding kinase 1, LPS, lipopolysaccharides, Surgery, GSDMD-N, N-terminal fragment of GSDMD, cGAMP, cyclic guanosine monophosphate-adenosine monophosphate, nDNA, nuclear DNA, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f78f03c1ea030072286a73467e72f2Test
https://pubmed.ncbi.nlm.nih.gov/34334261Test

المؤلفون: Jose J.G. Marin, Maria J. Monte, Malgorzata Milkiewicz, Miren Bravo, Fernando Lopitz-Otsoa, Javier Crespo, Carlos Ferre-Aracil, Sofia Lachiondo-Ortega, Virginia Gutiérrez-de-Juan, Marta Varela-Rey, Jose Luis Calleja, Teresa C. Delgado, María L. Martínez-Chantar, Mercedes Robles, Piotr Milkiewicz, Marina Serrano-Macia, Pablo Fernández-Tussy, Juan Anguita, Marcos López-Hoyos, Shelly C. Lu, David Fernández-Ramos, Naroa Goikoetxea-Usandizaga, Paula Iruzubieta, Natalia Elguezabal, Lucía Barbier-Torres, Jorge Simón, Mercedes Rincon

المساهمون: Universidad de Cantabria

المصدر: JHEP Reports, Vol 3, Iss 3, Pp 100276-(2021)
JHEP Reports Volume 3, Issue 3, June 2021, 100276
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
JHEP Reports

مصطلحات موضوعية: Mitochondrial ROS, MMP, mitochondrial membrane potential, LSM, liver stiffness, MPO, myeloperoxidase, AST, aspartate aminotransferase, Pgc1α, peroxisome proliferator-activated receptor gamma coactivator 1-alpha, RC799-869, Pharmacology, p-JNK, phosphor-JNK, TNF, tumour necrosis factor, Tfam, transcription factor A mitochondrial, Ccr5, C-C motif chemokine receptor 5, Immunology and Allergy, CLD, cholestatic liver disease, MLKL, mixed-lineage kinase domain-like pseudokinase, shRNA, small hairpin RNA, ANA, antinuclear antibodies, Hif-1α, hypoxia-inducible factor 1-alpha, Liver injury, GCDCA, glycochenodeoxycholic acid, Cholestasis, Bile acid, MCJ, methylation-controlled J, SDH2, succinate dehydrogenase, Gastroenterology, α-SMA, alpha-smooth muscle actin, Pgc1β, peroxisome proliferator-activated receptor gamma coactivator 1-beta, ROS, Bile duct ligation, Diseases of the digestive system. Gastroenterology, Mitochondria, Ccr2, C-C motif chemokine receptor 2, Ezh2, enhancer of zeste homolog 2, Mitochondrial respiratory chain, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, JNK, c-Jun N-terminal kinase, BA, bile acid, BAX, BCL2 associated X, RT, room temperature, VCTE, vibration-controlled transient elastography, HSC, hepatic stellate cells, Research Article, PARP, poly (ADP-ribose) polymerase, Cxcl1, C-X-C motif chemokine ligand 1, p-MLKL, phosphor-MLKL, medicine.drug_class, mRNA, messenger ribonucleic acid, ETC, electron transport chain, Nrf1, nuclear respiratory factor 1, APRI, AST to platelet ratio index, BDL, bile duct ligation, Ccl2, C-C motif chemokine ligand 2, MPT, mitochondrial permeability transition, UDCA, ursodeoxycholic acid, Primary sclerosing cholangitis, AMA-M2, antimitochondrial M2 antibody, ROS, reactive oxygen species, BCL-Xl, B-cell lymphoma-extra large, ALT, alanine aminotransferase, Internal Medicine, medicine, Trail, TNF-related apoptosis-inducing ligand, tBIL, total bilirubin, KO, knockout, ALP, alkaline phosphatase, Hepatology, business.industry, medicine.disease, WT, wild-type, MCJ, PSC, primary sclerosing cholangitis, DCA, deoxycholic acid, Mitochondrial permeability transition pore, siRNA, small interfering RNA, Ucp2, uncoupling protein 2, Fxr, farnesoid X receptor, Hepatic stellate cell, PBC, primary biliary cholangitis, business, Cyp7α1, cholesterol 7 alpha-hydroxylase, BCL-2, B-cell lymphoma 2, MAPK, mitogen-activated protein kinase, Abs, antibodies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260a6a78478feb3a4a8f609b4afaa257Test
https://pubmed.ncbi.nlm.nih.gov/33997750Test

المؤلفون: Ling Shao, Zhang-Xu Liu, Janet Kwok, Katherine Donovan, Brian T. Lee, Andrea Iorga, Layla Shojaie, Heather S. Johnson, Lily Dara, Mariam Aghajan, Jo Suda

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, MAP Kinase Kinase 4, RHIM, RIP homotypic interaction motif, receptor interacting protein, Apoptosis, Pharmacology, ASK1, apoptosis signal-regulating kinase 1, Biochemistry, Severity of Illness Index, necrosis, Mice, GSH, glutathione, AAC, asparagine, TBP, TATA box binding protein, ASK1, GAC, aspartic acid, drug action, TNFAIP3, RIPK1/3, receptor interacting protein kinase-1/3, TNF, tumor necrosis factor, Chemistry, Kinase, Co-IP, Coimmunoprecipitation, digestive, oral, and skin physiology, A20HepCKO, targeted hepatocyte A20 knockout, PHB1, prohibitin-1, cell death, TNFAIP3, TNF-induced protein 3, also known as A20, Liver, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, Receptor-Interacting Protein Serine-Threonine Kinases, JNK, c-Jun N-terminal kinase, LPS, lipopolysaccharide, Chemical and Drug Induced Liver Injury, Protein Binding, Research Article, Programmed cell death, hepatotoxicity, RIPK1, RCD, regulated cell death, MAP Kinase Signaling System, Necroptosis, necroptosis, APAP, acetaminophen, Mice, Transgenic, ASO, antisense oligonucleotide, MKK4, MAP2 kinase mitogen-activated protein kinase 4, MAP Kinase Kinase Kinase 5, RIPK3, drug induced liver injury, 03 medical and health sciences, ROS, reactive oxygen species, Downregulation and upregulation, RIPK1HepCKO, targeted hepatocyte RIPK1 knockout, ALT, alanine aminotransferase, Animals, Molecular Biology, Tumor Necrosis Factor alpha-Induced Protein 3, Acetaminophen, DYKDDDK Tag, Flag Tag, MLKL, mixed lineage kinase domain like pseudokinase, 030102 biochemistry & molecular biology, RIPK1D138N, kinase dead RIPK1 knock-in, Nec-1, necrostatin-1, DMSO, Dimethyl sulfoxide, Cell Biology, 030104 developmental biology, Gene Expression Regulation, MAPK, mitogen-activated protein kinases, siRNA, small interfering RNA, Hepatocytes, NFkB, nuclear factor kB, NAPQI, N-acetyl-p-benzoquinone imine, PMH, primary mouse hepatocyte

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432b35121380a9409ee2a1dc4c870f71Test
https://pubmed.ncbi.nlm.nih.gov/33460648Test

المؤلفون: Jihye Lee, Hee-Seop Lee, Seong-Ho Lee, Dmitriy Smolensky

المصدر: International Immunopharmacology

مصطلحات موضوعية: ERK, Extracellular signal-Regulated Kinase, HPU, Helicobactor Pylori Urease, IR, Ischemia/reperfusion, iNOS, Inducible Nitric Oxide Synthase, PERK, Protein kinase R-like Endoplasmic Reticulum Kinase, Alcohol, C/EBPα, CCAT/enhancer Binding Protein α, RIP3, Receptor Interacting Serine/Threonine- Protein kinase3, CXCL11, C-X-C Motif Chemokine 11, IBD, Inflammatory Bowel Disease, DCNB, 2,4-Dinitro-chlorobenzene, IRE1, Inositol-requiring Enzyme 1, 0302 clinical medicine, ACE2, Angiotensin Converting Enzyme 2, Medicine, 4E-BP1, Eukaryotic Translation Initiation Factor 4E Binding Protein 1, SOD, Superoxide Dismutase, 5-HT, 5-Hydroxytryptamine, LPS, Lipopolysaccharide, TLR2, Toll-like Receptor 2, media_common, ER, Estrogen Receptor, IFNγ, Interferon γ, Nrf2, Nuclear Factor Erythroid 2-Related Factor 2, NF-κB, Nuclear Factor κ-light-chain-enhancer of activated B cells, VDCC, Voltage-Dependent Ca2+ Channel, Pogostemon, SYN1, Synapsin-1, PXR, Pregnane X Receptor, 030220 oncology & carcinogenesis, IP3R, Inositol Triphosphate Receptor, Sesquiterpenes, PSD-95, Postsynaptic Density Protein 95, TPH1, Tryptophan Hydroxylase 1, Drug, media_common.quotation_subject, Immunology, CUMS, Chronic Unpredictable Mild Stress, ZO-1, Zonula Occludens-1, Article, WHO, World Health Organization, 03 medical and health sciences, food, ICAM-1, Intracellular Adhesion Molecule-1, Humans, VLDL, Very Low Density Lipoprotein, Pharmacology, IDO-1, Indoleamine 2,3-dioxygenease-1, TNFα, Tumor Necrosis Factor α, MAPK, Mitogen-Activated Protein Kinase, NO, Nitric Oxide, CAT, Catalase, 030104 developmental biology, Patchouli alcohol, mTOR, Mammalian Target of Rapamycin, chemistry, PI3K, Phosphoinositol-3 Kinase, RdRp, RNA-Dependent RNA Polymerase, 0301 basic medicine, CXCL10, C-X-C Motif Chemokine 10, PLpro, Papain-like Protease, Anti-Inflammatory Agents, 3CLpro, 3C-Like Protease, PGE2, Prostaglandin E2, Health benefits, COX2, Cyclooxygenase 2, MLKL, Mixed Lineage Kinase Domain-Like Pseudokinase, chemistry.chemical_compound, 5-FU, 5-Fluorouracil, Immunology and Allergy, CXCL9, C-X-C Motif Chemokine 9, eNOS, Endothelial Nitric Oxide Synthase, biology, Traditional medicine, respiratory system, 5-HTP, 5-Hydroxytryptophan, VCAM-1, Vascular Cell Adhesion Molecule 1, NLRP3, NOD-, LRR- and Pyrin Domain-containing Protein 3, Immunosuppressive Agents, food.ingredient, ATF6, Activating Transcription Factor 6, DSS, Dextran Sulfate Sodium, TXNIP, Thioredoxin Interacting Protein, ROCCs, Receptor-operated Ca2+ Channels, Functional food, PA, Patchouli Alcohol, SCFA, Short Chain Fatty Acid, MDA, Malondialdehyde, Biological mechanisms, RyRs, Ryanodine Receptors, Lung protection, business.industry, PHE, Phenylephrine, GSH-px, Glutathione Peroxidase, MMP9, Matrix Metalloproteinase 9, biology.organism_classification, Antineoplastic Agents, Phytogenic, DTH, Delayed Type Hypersensitivity, PPARγ, Peroxisome Proliferator Activated Receptor γ, HO-1, Heme Oxidase-1, Molecular targets, EGFR, Epidermal Growth Factor Receptor, Kyn, L-Kynurenine, MCP-1, Monocyte Chemoattractant Protein-1, Patchouli, business, human activities, ROS, Reactive Oxygen Species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e0bef40b542aa0945c4a6b4a7afa05Test
https://doi.org/10.1016/j.intimp.2020.107056Test