المؤلفون: Oshin Miranda, Mariya Farooqui, Jill M. Siegfried

المصدر: Cancers; Volume 10; Issue 9; Pages: 280

مصطلحات موضوعية: hepatocyte growth factor (HGF), c-Met (mesenchymal epithelial transition factor or hepatocyte growth factor receptor), targeted therapy, lung cancer

وصف الملف: application/pdf

العلاقة: https://dx.doi.org/10.3390/cancers10090280Test

الإتاحة: https://doi.org/10.3390/cancers10090280Test

المؤلفون: Mari Ishigami-Yuasa, Tetsuro Watabe, Hiroyuki Harada, Rina Takayama, Hiroyuki Kagechika, Kazuki Takahashi, Katarzyna A. Podyma-Inoue, Shintaro Sakakitani

المصدر: Cancer Science

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Down-Regulation, Mice, Nude, β2‐adrenergic receptor, isoxsuprine, Metastasis, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell, Molecular, and Stem Cell Biology, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, Androgen Receptor Antagonists, Animals, Humans, Medicine, Receptor, Mice, Inbred BALB C, business.industry, Mesenchymal stem cell, Cancer, Mesenchymal Stem Cells, Cell migration, General Medicine, MET (mesenchymal‐epithelial transition), medicine.disease, Propranolol, oral squamous cell carcinoma, tumor growth, Cell Transformation, Neoplastic, Phenotype, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Isoxsuprine, Carcinoma, Squamous Cell, Cancer research, Original Article, Mouth Neoplasms, Receptors, Adrenergic, beta-2, business, Signal Transduction, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78920b93d65ae08df3a7c9c289e7f3a5Test
https://doi.org/10.1111/cas.14670Test

المؤلفون: Jiang, Jian, Zheng, Min, Zhang, Mei, Yang, Xiao, Li, Li, Wang, Sha-sha, Wu, Jia-shun, Yu, Xiang-hua, Wu, Jing-biao, Pang, Xin, Tang, Ya-jie, Tang, Ya-ling, Liang, Xin-hua

المصدر: Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Adult, Male, Original article, Epithelial-Mesenchymal Transition, BC, Breast cancer, p38 Mitogen-Activated Protein Kinases, Transforming Growth Factor beta1, Mice, Transforming Growth Factor beta2, HNSCC, Head and neck squamous cell carcinoma, Animals, Humans, RCC, Renal cell carcinoma, Aged, Neoplasm Staging, Homeodomain Proteins, EMT, Epithelial mesenchymal transition, Squamous Cell Carcinoma of Head and Neck, Gene Expression Profiling, Middle Aged, Proto-Oncogene Proteins c-met, Xenograft Model Antitumor Assays, miRNAs, MicroRNAs, Gene Expression Regulation, Neoplastic, stomatognathic diseases, ChIP, Chromatin immunoprecipitation assays, Disease Models, Animal, MicroRNAs, Gene Knockdown Techniques, Asymptomatic Diseases, Female, RNA Interference, Neoplasm Grading, Biomarkers, MET, Mesenchymal epithelial transition, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::ee4e844722ee01d6291a113801852ebaTest
http://europepmc.org/articles/PMC6324219Test

المؤلفون: Dong Seop Kang, Sang Jun Park, Joo Young Lee, Kang Moo Huh, Han Chang Kang, Yeon Su Choi, Min Suk Shim, Gantumur Battogtokh, Hye Suk Lee, Yong-Yeon Cho

المصدر: Acta Pharmaceutica Sinica B, Vol 8, Iss 6, Pp 862-880 (2018)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: 0301 basic medicine, AD, Alzheimer׳s disease, C-dots, carbon dots, MLS, mitochondria localization sequences, OXPHOS, oxidative phosphorylation, MPO, myeloperoxidase, TPP, triphenylphosphonium, 4-AT, 4-amino-TEMPO, mitoTEMPO, (2-(2,2,6,6-tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium), Review, GPX, glutathione peroxidase, Mitochondrion, mtPt, mitochondria-targeting (Fx,r)3-platinum(II), Antioxidants, LA, lipoic acid, VDAC/ANT, voltage-dependent anion channel/adenine nucleotide translocase, chemistry.chemical_compound, DQA, dequalinium, Direct conjugation, 0302 clinical medicine, MPP, mitochondria-penetrating peptides, SS peptide, Szeto-Schiller peptides, Dmt, dimethyltyrosine, Aβ, beta amyloid, AIE, aggregation-induced emission, 5-FU, 5-Fluorouracil, NitDOX, nitrooxy-DOX, mtCbl, (Fx,r)3-chlorambucil, General Pharmacology, Toxicology and Pharmaceutics, Cytotoxicity, Inner mitochondrial membrane, PD, Parkinson׳s disease, media_common, IMS, intermembrane space, BODIPY, boron-dipyrromethene, Chemistry, MET, mesenchymal-epithelial transition, DDS, drug delivery system, F16, (E)-4-(1H-indol-3-ylvinyl)-N-methylpyridinium iodide, VES, vitamin E succinate, MitoLA, TPP-lipoic acid, Nit, nitrooxy, LAH2, dihydrolipoic acid, Biochemistry, COX, cytochrome c oxidase, GS, gramicidin S, PDT, photodynamic therapy, 030220 oncology & carcinogenesis, DIPPMPO, 5-(diisopropoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide, OMM, outer mitochondrial membrane, Phe, phenylalanine, IMM, inner mitochondrial membrane, IOA, imidazole-substituted oleic acid, Lys, lysine, Drug, CoA, coenzyme A, ATP, adenosine triphosphate, MitoE, TPP-vitamin E, media_common.quotation_subject, TPEY-TEMPO, [2-(1-oxyl-2,2,6,6-tetramethylpiperidin-4-ylimino)-ethyl]-triphenyl-phosphonium, PS, photosensitizer, Sensing agents, Mitochondria-targeting, RNS, reactive nitrogen species, 03 medical and health sciences, MitoQ, TPP-ubiquinone, ROS, reactive oxygen species, In vivo, SkQ1, Skulachev ion-quinone, PTPC, permeability transition pore complex, SOD, superoxide dismutase, MitoChlor, TPP-chlorambucil, αTOS, alpha-tocopheryl succinate, EPR, enhanced permeability and retention, Dequalinium, Arg, arginine, (Fx, r)3, (l-cyclohexyl alanine-d-arginine)3, XO, xanthine oxidase, TEMPOL, 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl, HTPP, 5-(4-hydroxy-phenyl)-10,15,20-triphenylporphyrin, PET, photoinduced electron transfer, lcsh:RM1-950, Tyr, tyrosine, In vitro, mtDNA, mitochondrial DNA, MitoVES, TPP-vitamin E succinate, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, CZBI, carbazole and benzo[e]indolium, Anticancer agents, DEPMPO, 5-(diethylphosphono)-5-methyl-1-pyrroline N-oxide, CAT, catalase, nDNA, nuclear DNA, Conjugate

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e4ca6cbbf78d2cfe5750be73f51ab1Test
http://www.sciencedirect.com/science/article/pii/S2211383518300583Test

المؤلفون: Thomas Valerius, Paul W. H. I. Parren, Janine Schuurman, Joost J. Neijssen, William R. Strohl, Kristen M. Chevalier, Luus Wiegman, Cardoso Rosa Maria Fernandes, Mark L. Chiu, Sheri Moores, G. Mark Anderson

المصدر: The Journal of Biological Chemistry
Journal of Biological Chemistry, 296. ELSEVIER

مصطلحات موضوعية: 0301 basic medicine, TGF alpha, Lung Neoplasms, Sema domain, non-small cell lung cancer (NSCLC), Apoptosis, cFAE, controlled Fab-arm exchange, TKI, tyrosine kinase inhibitor, Biochemistry, Epitope, Tyrosine-kinase inhibitor, Mice, amivantamab, NSCLC, non–small cell lung cancer, Carcinoma, Non-Small-Cell Lung, FACS, fluorescence-activated cell sorting, Antibodies, Bispecific, Drug Discovery, Tumor Cells, Cultured, BsAb, bispecific antibody, EGFR exon 20 insertion, Epidermal growth factor receptor, Antibody-dependent cell-mediated cytotoxicity, TGI, tumor growth inhibition, biology, Chemistry, bispecific anti-EGFR×MET antibody, Proto-Oncogene Proteins c-met, ErbB Receptors, combinatorial screening, Female, MET amplification, Research Article, crystal structure, medicine.drug_class, Monoclonal antibody, 03 medical and health sciences, PDB, Protein Data Bank, non–small cell lung cancer (NSCLC), medicine, Animals, Humans, TGFα, transforming growth factor alpha, mAb, monoclonal antibody, Molecular Biology, Cell Proliferation, ADCC, antibody-dependent cellular cytotoxicity, 030102 biochemistry & molecular biology, MET, mesenchymal–epithelial transition factor, Cell Biology, medicine.disease, Xenograft Model Antitumor Assays, EGFR, epidermal growth factor receptor, epitope mapping, 030104 developmental biology, Cancer research, biology.protein, HGF, hepatocyte growth factor

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca933b2c86ba6635402921bd327c1a34Test
https://hdl.handle.net/1887/3256851Test

المؤلفون: Bushra Rahman, Ehtesham Arif, Pei Wen, Zhe Han, Joshua H. Lipschutz, Avinash Singh, Sang Ho Kwon, Deepak Nihalani, Glenn P. Lobo, Pankaj Srivastava, Ashish K. Solanki, Wayne R. Fitzgibbon, Milos N. Budisavljevic, Christopher M. Furcht, Lawrence B. Holzman, Matthew J. Lazzara

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Kidney Glomerulus, Kidney, urologic and male genital diseases, Biochemistry, GST, glutathione S-transferase, Podocyte, Mice, HGF, PS, protamine sulfate, Phosphorylation, Receptor, MET, mesenchymal epithelial transition, biology, Hepatocyte Growth Factor, Podocytes, Chemistry, female genital diseases and pregnancy complications, Cell biology, phosphorylation–dephosphorylation, Intercellular Junctions, medicine.anatomical_structure, SHP-2, SH2 domain–containing protein tyrosine phosphatase-2, SHP-2, Slit diaphragm, Hepatocyte growth factor, Research Article, Glomerular Filtration Rate, Protein Binding, Signal Transduction, medicine.drug, Cell Line, FL, full length, Dephosphorylation, Nephrin, medicine, Animals, Humans, Molecular Biology, KD, knockdown, urogenital system, Membrane Proteins, Cell Biology, Actin cytoskeleton, ECD, extracellular domain, biology.protein, HGF, hepatocyte growth factor, Peptides, SNS, sticks-and-stones, CD, cytoplasmic domain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408b60f6059aaeab5052baf396505dd2Test
https://doi.org/10.1016/j.jbc.2021.101079Test

المؤلفون: Kuang Hong Neoh, Guangdong Wu, Anqi Chen, Ray P. S. Han, Kok Suen Cheng, Shuiyu Chen, Yukun Sun, Zhewen Tang, Menghua Dai, Poh Foong Lee

المصدر: EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, AIC, Akaike information criterion, MET, Mesenchymal-epithelial transition, Research paper, RFS, Relapse free survival, E, M, H, T, Epithelial, Mesenchymal, Hybrid, Total, Kaplan-Meier Estimate, Metastasis, 0302 clinical medicine, Circulating tumor cell, EMT, Epithelial-mesenchymal transition, PPV, Positive predictive value, SD, Standard deviation, IMDM, Iscove's Modified Dulbecco's Medium, Neoplasm Metastasis, TMN, Tumor-Node-Metastasis, PDMS, Polydimethylsiloxane, PFA, Paraformaldehyde, CE, Capture efficiency, medicine.diagnostic_test, CTC, Circulating tumor cell, TU, Triangular units, WBC, White blood cell, Hazard ratio, mROC, multivariable receiver operating characteristic, General Medicine, Venous blood, EDTA, Ethylenediaminetetraacetic acid, Neoplastic Cells, Circulating, Prognosis, PDAC, Pancreatic ductal adenocarcinoma, medicine.anatomical_structure, Phenotype, PDAC overall survival assessment, 030220 oncology & carcinogenesis, AJCC, American Joint Committee on Cancer, CT, Computed tomography, Female, E-cad, E-cadherin, mLBR, Multivariable binary logistic regression, Carcinoma, Pancreatic Ductal, medicine.medical_specialty, VIF, Variance inflation factor, CU, Capture unit, ROC, Receiver operating characteristic, PBS, Phosphate buffered saline, DMEM, Dulbecco's Modified Eagle Medium (DMEM), General Biochemistry, Genetics and Molecular Biology, Immunophenotyping, 03 medical and health sciences, mAUC, Multivariable area under the curve, BSA, Bovine serum albumin, Pancreatic cancer, Internal medicine, White blood cell, Cell Line, Tumor, CTC phenotyping blood test, medicine, Biomarkers, Tumor, Blood test, Humans, NPV, Negative predictive value, LOOCV, Leave-one-out cross-validation, Neoplasm Staging, Proportional Hazards Models, Receiver operating characteristic, business.industry, Reproducibility of Results, medicine.disease, AUC, Area under the curve, PI, Propidium iodide, HR, hazard ratio, digestive system diseases, C-index, Concordance, Pancreatic Neoplasms, STR, Short tandem repeat, 030104 developmental biology, OS, Overall survival, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, business, PDAC metastatic assessment, DAPI, 4′,6-diamidino-2-phenylindole

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5c11fff5e53188b7b192a582557ce2Test
https://pubmed.ncbi.nlm.nih.gov/31375425Test

المؤلفون: Xiangming Guan

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 5, Pp 402-418 (2015)

مصطلحات موضوعية: CA15-3, Pathology, HA, hyaluronan, JAK, the Janus kinases, Detachment, medicine.medical_treatment, Review, PDGF, platelet-derived growth factor, Metastasis, DISC, death-inducing signaling complex, Invasion, General Pharmacology, Toxicology and Pharmaceutics, FAs, focal adhesions, IKK, IκB kinase, VN, vitronectin, Migration, Cancer, TGF-β, transforming growth factor β, biology, TME, tumor microenvironment, PI3K, phosphatidylinositol 3-kinase, VCAMs, vascular cell adhesion molecules, VEGF, vascular endothelial growth factor, Primary tumor, ECM, extracellular matrix, CAT, collective amoeboid transition, CSF-1, chemokine colonystimulating factor–1, FAK, focal adhesion kinase, EGFR, EGF receptor, Adhesion, STATs, signal transducers and activators of transcription, EMT, epithelial–mesenchymal transition, Platelet-derived growth factor receptor, LN, laminin, medicine.medical_specialty, MAT, mesenchymal to amoeboid transition, MET, mesenchymal–epithelial transition, CTGF, connective tissue growth factor, Cancer stem cell, HIFs, hypoxia-inducible factors, TAMs, tumor-associated macrophages, medicine, CCR3, chemokine receptor 3, FN, fibronectin, EGF, epidermal growth factor, Tumor microenvironment, business.industry, lcsh:RM1-950, COX2, cyclooxygenase 2, CXCR2, chemokine receptor type 2, medicine.disease, Col, collagen, FGF, fibroblast growth factor, Radiation therapy, lcsh:Therapeutics. Pharmacology, BM, basement membrane, Cancer research, biology.protein, HGF, hepatocyte growth factor, MMPs, matrix metalloproteinases, CAMs, cell adhesion molecules, business, MAPK, mitogen-activated protein kinase, CAFs, cancer-associated fibroblasts, CCL2, chemokine (C–C motif) ligand 2

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3f6f06ec2fa7a03c41137b4a13ce17Test
https://doi.org/10.1016/j.apsb.2015.07.005Test

المؤلفون: Renato V. Iozzo, Achilleas D. Theocharis, Thomas Neill, Nikos K. Karamanos

المصدر: Matrix Biology Plus, Vol 6, Iss, Pp 100038-(2020)
Matrix Biology Plus

مصطلحات موضوعية: HA, hyaluronan, Computer science, Biochemistry, miR, microRNA, tPA, tissue-type plasminogen activator, Matrix (mathematics), Human disease, TGFβ, transforming growth factor β, PG, proteoglycans, lcsh:QH301-705.5, Cancer, Cognitive science, Complex matrix, MET, mesenchymal-epithelial transition, uPA, urokinase-type plasminogen activator, LEKTI, lympho-epithelial Kazal-type inhibitor, EMILIN2, elastin microfibril interfacer 2, VEGF, vascular endothelial growth factor, Phenotype, Reciprocity (evolution), ECM, extracellular matrix, UVR, ultraviolet radiation, ERβ, estrogen receptor β, PLL, poly-l-lysine, SLRP, small leucine rich proteoglycans, Research strategies, MMP, matrix metalloproteinases, SSR, solar-simulated radiation, ADAM, a disintegrin and metalloproteinases, Proteoglycans, AGE, advanced glycation end products, Collagen, Methodologies, RTK, receptor tyrosine kinase, EMT, epithelial-mesenchymal transition, HAS2-AS1, HAS2 antisense 1, LOX, lysyl oxidases, Histology, EMILIN1, elastin microfibril interfacer 1, LTBP, latent TGFβ-binding proteins, Biophysics, Original research, Article, IR-A, insulin receptor A, OB, osteoblast, ROS, reactive oxygen species, IBC, inflammatory breast cancer, Genetics, IGF-IR, insulin growth factor I receptor, HAS2, hyaluronan synthase 2, PARs, protease activated receptors, Molecular Biology, EGF, epidermal growth factor, HMGA2, high-mobility group AT-Hook 2, HB-EGF, heparin binding EGF, MAGP, microfibril-associated glycoproteins, ERα, estrogen receptor α, Cell Biology, Human body, EGFR, epidermal growth factor receptor, OI, osteogenesis imperfecta, lcsh:Biology (General), TNT, tunneling nanotubes, GBM, glioblastoma, Angiogenesis, DDR1, discoidin domain receptor 1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0706f5167c8f3bf2dfb334f7e3546aTest
https://doi.org/10.1016/j.mbplus.2020.100038Test

المؤلفون: Mariya Farooqui, Oshin Miranda, Jill M. Siegfried

المصدر: Cancers
Cancers, Vol 10, Iss 9, p 280 (2018)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, C-Met, Angiogenesis, hepatocyte growth factor (HGF), Review, lcsh:RC254-282, Receptor tyrosine kinase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Medicine, Mesenchymal–epithelial transition, Lung cancer, biology, business.industry, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, targeted therapy, lung cancer, 030104 developmental biology, Oncology, chemistry, Hepatocyte Growth Factor Receptor, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Hepatocyte growth factor, c-Met (mesenchymal epithelial transition factor or hepatocyte growth factor receptor), business, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3413cba390ca7547d704ff8a4689a450Test
https://pubmed.ncbi.nlm.nih.gov/30134579Test