المؤلفون: Adoue, Véronique, Binet, Bénédicte, Malbec, Agathe, Fourquet, Joanna, Romagnoli, Paola, van Meerwijk, Joost, Pm, Amigorena, Sebastian, Joffre, Olivier

المساهمون: Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Immunité et cancer (U932), Institut Curie Paris -Institut National de la Santé et de la Recherche Médicale (INSERM), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014)

المصدر: ISSN: 1074-7613 ; Immunity ; https://hal.science/hal-02369136Test ; Immunity, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩.

مصطلحات موضوعية: ERV, ESET, H3K9me3, SETDB1, T helper cell, Th1, exaptation, histone methyltransferase, lineage commitment, transposable elements, MESH: Animals, MESH: CD4-Positive T-Lymphocytes / immunology, MESH: Endogenous Retroviruses / immunology, MESH: Female, MESH: Histone Methyltransferases / immunology, MESH: Histone-Lysine N-Methyltransferase / immunology, MESH: Histones / immunology, MESH: Male, MESH: Mice, Inbred C57BL, MESH: Promoter Regions, Genetic / immunology, MESH: T-Lymphocytes, Helper-Inducer / immunology, MESH: Th1 Cells / immunology, MESH: Th2 Cells / immunology, MESH: Cell Differentiation / immunology, MESH: Cell Lineage / immunology, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30737147; hal-02369136; https://hal.science/hal-02369136Test; https://hal.science/hal-02369136/documentTest; https://hal.science/hal-02369136/file/S1074761319300032.pdfTest; PII: S1074-7613(19)30003-2; PUBMED: 30737147

الإتاحة: https://doi.org/10.1016/j.immuni.2019.01.003Test
https://hal.science/hal-02369136Test
https://hal.science/hal-02369136/documentTest
https://hal.science/hal-02369136/file/S1074761319300032.pdfTest

المؤلفون: Navarro, Séverine, Lazzari, Anne, Kanda, Akira, Fleury, Sébastien, Dombrowicz, David, Glaichenhaus, Nicolas, Julia, Valérie

المساهمون: Immunologie des muqueuses et inflammation, Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), This work was supported by a grant from the Fondation pour la Recherche Médicale and INSERM. S.N. was supported by a fellowship from the FRM, A.L. was supported by a fellowship from Vaincre la Mucoviscidose, and A.K is supported by a grant from the Agence Nationale de la Recherche (ANR)., We thank Nicolas Guy and the animal facility staff for their excellent animal care, as well as Julie Cazareth for the cell sorting experiments.

المصدر: ISSN: 1933-0219.

مصطلحات موضوعية: Th2, T reg, specific immunotherapy, asthma, immune tolerance, airway inflammation, MESH: Allergens/administration & dosage, MESH: Allergens/immunology, MESH: Disease Models, Animal, MESH: Immunoglobulin E/immunology, MESH: Inducible T-Cell Co-Stimulator Protein/metabolism, MESH: Interleukin-2 Receptor alpha Subunit/metabolism, MESH: Lymphocyte Activation/immunology, MESH: Mice, Transgenic, MESH: Ovalbumin/administration & dosage, MESH: Ovalbumin/immunology, MESH: Protozoan Proteins/immunology, MESH: Animals, MESH: Respiratory Hypersensitivity/immunology, MESH: Respiratory Hypersensitivity/metabolism, MESH: Respiratory Hypersensitivity/therapy, MESH: T-Lymphocytes, Regulatory/immunology, Regulatory/metabolism, MESH: Th2 Cells/immunology, MESH: Th2 Cells/metabolism, MESH: Antigens, Protozoan/immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25425267; inserm-01116372; https://inserm.hal.science/inserm-01116372Test; https://inserm.hal.science/inserm-01116372/documentTest; https://inserm.hal.science/inserm-01116372/file/Navarro-Muc%20Immunol.pdfTest; PUBMED: 25425267; PUBMEDCENTRAL: PMC5410219

الإتاحة: https://doi.org/10.1038/mi.2014.115Test
https://inserm.hal.science/inserm-01116372Test
https://inserm.hal.science/inserm-01116372/documentTest
https://inserm.hal.science/inserm-01116372/file/Navarro-Muc%20Immunol.pdfTest

المؤلفون: Beziat, Vivien, Li, Juan, Lin, Jian-Xin, Ma, Cindy, Li, Peng, Bousfiha, Aziz, Pellier, Isabelle, Zoghi, Samaneh, Baris, Safa, Keles, Sevgi, Gray, Paul, Du, Ning, Wang, Yi, Zerbib, Yoann, Levy, Romain, Leclercq, Thibaut, About, Frédégonde, Lim, Ai Ing, Rao, Geetha, Payne, Kathryn, Pelham, Simon, Avery, Danielle, Deenick, Elissa, Pillay, Bethany, Chou, Janet, Guery, Romain, Belkadi, Aziz, Guerin, Antoine, Migaud, Melanie, Rattina, Vimel, Ailal, Fatima, Benhsaien, Ibtihal, Bouaziz, Matthieu, Habib, Tanwir, Chaussabel, Damien, Marr, Nico, El-Benna, Jamel, Grimbacher, Bodo, Wargon, Orli, Bustamante, Jacinta, Boisson, Bertrand, Müller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Chandesris, Marie-Olivia, Titeux, Matthias, Fraitag, Sylvie, Alyanakian, Marie-Alexandra, Leruez-Ville, Marianne, Picard, Capucine, Meyts, Isabelle, Di Santo, James, P, Hovnanian, Alain, Somer, Ayper, Ozen, Ahmet, Rezaei, Nima, Chatila, Talal, Abel, Laurent, Leonard, Warren, Tangye, Stuart, G., Puel, Anne, Casanova, Jean-Laurent

المساهمون: Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rockefeller University New York, National Institutes of Health Bethesda, MD, USA (NIH), Garvan Institute of medical research, University of New South Wales Sydney (UNSW), CHU Ibn Rochd Casablanca, Université Hassan II Casablanca (UH2MC), Service d'Immuno-Hémato-Oncologie Pédiatrique, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Shahid Beheshti University of Medical Sciences Tehran (SBUMS), Universal Scientific Education and Research Network (USERN), Marmara University Kadıköy - İstanbul, Necmettin Erbakan University Konya, Turquie, Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Harvard Medical School Boston (HMS), Boston Children's Hospital, Centre d'infectiologie Necker-Pasteur CHU Necker, Institut Pasteur Paris (IP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sidra Medicine Doha, Qatar, Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Universitäts Klinikum Freiburg = University Medical Center Freiburg (Uniklinik), Sydney Children's hospital, Centre de Référence Déficits Immunitaires Héréditaires (CEREDIH), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Friedrich-Alexander Universität Erlangen-Nürnberg = University of Erlangen-Nuremberg (FAU), Genetic skin diseases : from disease mechanism to therapies (Equipe Inserm U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de pathologie CHU Necker, Service d'immuno-hématologie pédiatrique CHU Necker, Laboratoire de Virologie CHU Necker, Université Paris Descartes - Paris 5 (UPD5), Centre d'étude des Déficits Immunitaires, University Hospitals Leuven Leuven, Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), Hôpital Necker - Enfants Malades AP-HP, Istanbul University, Research Center for Immunodeficiencies Tehran, Iran, Tehran University of Medical Sciences (TUMS), University of New South Wales Canberra Campus (UNSW), Howard Hughes Medical Institute New York (HHMI), Howard Hughes Medical Institute (HHMI)-New York University School of Medicine, NYU System (NYU)-NYU System (NYU)-Rockefeller University New York -Columbia University Irving Medical Center (CUIMC), This work was supported by grants from INSERM, Paris Descartes University, Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (ANR-10-LABX-62-IBEID), the Jeffrey Modell Foundation Translational Research Program, the French National Research Agency (ANR, grant nos. GENCMCD-ANR-11-BSV3–005-01, HGDIFD-ANR-14-CE15-0006-01, NKIR-ANR-13-PDOC-0025-01, and EURO-CMC-ANR-14-RARE-0005-02), and grants awarded under the “Investissement d’avenir” program (grant no. ANR-10-IAHU-01), the National Institute of Allergy and Infectious Diseases of the NIH (grant nos. U01AI109697 and R01AI127564), the Rockefeller University, the Howard Hughes Medical Institute, the St. Giles Foundation, the Institut Pasteur, and FP7, under grant agreements 305578 (PathCO) and 317057 (HOMIN). We thank the Centre de Recherche Translationnelle (Institut Pasteur) for technical assistance. V.B. is supported by the ANR (grant no. NKIR-ANR-13-PDOC-0025-01). R.L. is supported by the INSERM Ph.D. program (Poste d’Accueil INSERM), a Fulbright grant (Franco-American commission), and a Philippe Foundation scholarship. Y.Z. received the “médaille d’or du Centre Hospitalier Universitaire d’Amiens.” Y.W. is supported by the French National Agency for Research on AIDS and Viral Hepatitis (ANRS, grant no. 13318). F. About holds a fellowship from Fondation pour la Recherche Médicale (FRM, grant no. FDM20140630671). A.G. is supported by an IFNGPHOX grant (no. ANR13-ISV3-0001-01) from ANR. B.G. was funded by BMBF (German Federal Ministry of Education and Research) grants 01E01303 and 01ZX1306F. I.M. is supported by a klinische onderzoeks-en opleidingsraad (clinical research council) grant from UZ Leuven, a klinisch onderzoeksfonds (clinical research fund) grant from KU Leuven, and an International Mobility Grant from Fonds voor Wetenschappelijk Onderzoek (fund for scientific research) Vlaanderen. C.S.M., E.K.D., and S.G.T. are supported by grants and fellowships from the National Health and Medical Research Council of Australia. C.S.M., P.G., E.K.D., and S.G.T. are members of CIRCA (Clinical Immunogenomics Research Consortia Australia), which is funded by the Office of Health and Medical Research of the NSW Government, the Jeffrey Modell Foundation, and the John Cook Brown Foundation. A.I.L. is a scholar of the Pasteur-Paris University International Ph.D. program and is supported by a Ph.D. International Training Network grant from the European Union’s Seventh Framework Program under grant agreement no. 317057 (HOMIN). T.A.C. was supported by a grant from the National Institute of Allergy and Infectious Diseases of the NIH (5R01AI065617). S.K. was supported by a grant from the Scientific and Technological Research Council of Turkey (1059B191300622). J.-X.L., P.L., N.D., and W.J.L. were supported by the Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH. A.P. was supported by an AP-HP interface contract., We thank the patients and their families for participating in this study. We thank J. E. Darnell and C. Mertens for advice and for providing reagents. We thank the members of the laboratory, especially F. Jabot-Hanin and V. Pedergnana, for their valuable input on linkage analysis, L. Amar, Y. Nemirovskaya, D. Papandrea, E. Anderson, M. Woollett, C. Desvallées, C. Patissier, and M. Corrias for administrative assistance, E. Jouanguy and Y. Itan for helpful discussions, S. Boucherit for clinical data collection, S. Jacques and the Cochin genomics platform for microarray experiments, and N. Goudin and R. Desveaux of the Necker Institute Imaging Facility.

المصدر: ISSN: 2470-9468 ; Science Immunology ; https://hal.science/hal-02392068Test ; Science Immunology, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩.

مصطلحات موضوعية: MESH: Adolescent, MESH: Adult, MESH: Job Syndrome/genetics, MESH: Job Syndrome/immunology, MESH: Cell Differentiation/genetics, MESH: Loss of Function Mutation, MESH: Lymphocyte Count, MESH: Male, MESH: Middle Aged, MESH: Pedigree, MESH: Promoter Regions, Genetic/genetics, MESH: RNA, Messenger/metabolism, MESH: Gene Expression Regulation/immunology, MESH: STAT3 Transcription Factor/genetics, MESH: STAT3 Transcription Factor/immunology, MESH: STAT3 Transcription Factor/metabolism, MESH: Cell Differentiation/immunology, MESH: Th17 Cells/immunology, MESH: Th17 Cells/metabolism, MESH: Th2 Cells/immunology, MESH: Th2 Cells/metabolism, MESH: Transcription Factors/genetics, MESH: Transcription Factors/immunology, MESH: Genes, Recessive/genetics, MESH: Transcription Factors/metabolism, MESH: Transcription, Genetic/immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29907691; hal-02392068; https://hal.science/hal-02392068Test; PUBMED: 29907691; PUBMEDCENTRAL: PMC6141026

الإتاحة: https://doi.org/10.1126/sciimmunol.aat4956Test
https://hal.science/hal-02392068Test

المؤلفون: Warren J. Leonard, Nima Rezaei, Kathryn Payne, Isabelle Meyts, Laurent Abel, Cindy S. Ma, Marianne Leruez-Ville, Janet Chou, Alain Hovnanian, Jian-Xin Lin, Simon J. Pelham, Danielle T. Avery, Matthieu Bouaziz, Bethany Pillay, Tanwir Habib, Anne Puel, Sevgi Keles, Juan Li, Isabelle Pellier, Jamel El-Benna, Bernhard Fleckenstein, Ahmet Ozen, Vivien Béziat, Ingrid Müller-Fleckenstein, Damien Chaussabel, Samaneh Zoghi, Yi Wang, Paul Gray, Matthias Titeux, Yoann Zerbib, Talal A. Chatila, Marie-Alexandra Alyanakian, Capucine Picard, Orli Wargon, Ayper Somer, Marie-Olivia Chandesris, Thibaut Leclercq, Ibtihal Benhsaien, Aziz Belkadi, Jean-Laurent Casanova, Romain Lévy, Peng Li, Geetha Rao, Ai Ing Lim, James P. Di Santo, Nico Marr, Sylvie Fraitag, Frédégonde About, Elissa K. Deenick, Bertrand Boisson, Jacinta Bustamante, Mélanie Migaud, Bodo Grimbacher, Aziz Bousfiha, Fatima Ailal, Safa Baris, Antoine Guérin, Stuart G. Tangye, Romain Guery, Ning Du, Vimel Rattina

المساهمون: Imagine - Institut des maladies génétiques (IMAGINE - U1163), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rockefeller University [New York], National Institutes of Health [Bethesda] (NIH), Garvan Institute of Medical Research [Darlinghurst, Australia], University of New South Wales [Sydney] (UNSW), CHU Ibn Rochd [Casablanca], Université Hassan II [Casablanca] (UH2MC), Service d'Immuno-Hémato-Oncologie Pédiatrique, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Shahid Beheshti University of Medical Sciences [Tehran] (SBUMS), Shahid Beheshti University, Universal Scientific Education and Research Network (USERN), Marmara University [Kadıköy - İstanbul], Necmettin Erbakan University [Konya, Turquie], Immunité Innée, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Harvard Medical School [Boston] (HMS), Boston Children's Hospital, Centre d'infectiologie Necker-Pasteur [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Sidra Medicine, Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Freiburg University Medical Center, Sydney children's hospital, Centre de Référence Déficits Immunitaires Héréditaires (CEREDIH), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Necker - Enfants Malades [AP-HP], Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Genetic skin diseases : from disease mechanism to therapies (Equipe Inserm U1163), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de pathologie [CHU Necker], Service d'immuno-hématologie pédiatrique [CHU Necker], Laboratoire de Virologie [CHU Necker], Université Paris Descartes - Paris 5 (UPD5), Centre d'étude des Déficits Immunitaires, University Hospitals Leuven [Leuven], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Istanbul University, Research Center for Immunodeficiencies [Tehran, Iran], Tehran University of Medical Sciences (TUMS), University of New South Wales [Canberra Campus] (UNSW), Howard Hughes Medical Institute [New York], New York University School of Medicine, NYU System (NYU)-NYU System (NYU)-Rockefeller University [New York]-Columbia University Irving Medical Center (CUIMC), This work was supported by grants from INSERM, Paris Descartes University, Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (ANR-10-LABX-62-IBEID), the Jeffrey Modell Foundation Translational Research Program, the French National Research Agency (ANR, grant nos. GENCMCD-ANR-11-BSV3–005-01, HGDIFD-ANR-14-CE15-0006-01, NKIR-ANR-13-PDOC-0025-01, and EURO-CMC-ANR-14-RARE-0005-02), and grants awarded under the 'Investissement d’avenir' program (grant no. ANR-10-IAHU-01), the National Institute of Allergy and Infectious Diseases of the NIH (grant nos. U01AI109697 and R01AI127564), the Rockefeller University, the Howard Hughes Medical Institute, the St. Giles Foundation, the Institut Pasteur, and FP7, under grant agreements 305578 (PathCO) and 317057 (HOMIN). We thank the Centre de Recherche Translationnelle (Institut Pasteur) for technical assistance. V.B. is supported by the ANR (grant no. NKIR-ANR-13-PDOC-0025-01). R.L. is supported by the INSERM Ph.D. program (Poste d’Accueil INSERM), a Fulbright grant (Franco-American commission), and a Philippe Foundation scholarship. Y.Z. received the 'médaille d’or du Centre Hospitalier Universitaire d’Amiens.' Y.W. is supported by the French National Agency for Research on AIDS and Viral Hepatitis (ANRS, grant no. 13318). F. About holds a fellowship from Fondation pour la Recherche Médicale (FRM, grant no. FDM20140630671). A.G. is supported by an IFNGPHOX grant (no. ANR13-ISV3-0001-01) from ANR. B.G. was funded by BMBF (German Federal Ministry of Education and Research) grants 01E01303 and 01ZX1306F. I.M. is supported by a klinische onderzoeks-en opleidingsraad (clinical research council) grant from UZ Leuven, a klinisch onderzoeksfonds (clinical research fund) grant from KU Leuven, and an International Mobility Grant from Fonds voor Wetenschappelijk Onderzoek (fund for scientific research) Vlaanderen. C.S.M., E.K.D., and S.G.T. are supported by grants and fellowships from the National Health and Medical Research Council of Australia. C.S.M., P.G., E.K.D., and S.G.T. are members of CIRCA (Clinical Immunogenomics Research Consortia Australia), which is funded by the Office of Health and Medical Research of the NSW Government, the Jeffrey Modell Foundation, and the John Cook Brown Foundation. A.I.L. is a scholar of the Pasteur-Paris University International Ph.D. program and is supported by a Ph.D. International Training Network grant from the European Union’s Seventh Framework Program under grant agreement no. 317057 (HOMIN). T.A.C. was supported by a grant from the National Institute of Allergy and Infectious Diseases of the NIH (5R01AI065617). S.K. was supported by a grant from the Scientific and Technological Research Council of Turkey (1059B191300622). J.-X.L., P.L., N.D., and W.J.L. were supported by the Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH. A.P. was supported by an AP-HP interface contract., We thank the patients and their families for participating in this study. We thank J. E. Darnell and C. Mertens for advice and for providing reagents. We thank the members of the laboratory, especially F. Jabot-Hanin and V. Pedergnana, for their valuable input on linkage analysis, L. Amar, Y. Nemirovskaya, D. Papandrea, E. Anderson, M. Woollett, C. Desvallées, C. Patissier, and M. Corrias for administrative assistance, E. Jouanguy and Y. Itan for helpful discussions, S. Boucherit for clinical data collection, S. Jacques and the Cochin genomics platform for microarray experiments, and N. Goudin and R. Desveaux of the Necker Institute Imaging Facility., Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Garvan Institute of medical research, Immunité Innée - Innate Immunity, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sidra Medicine [Doha, Qatar], Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Universitäts Klinikum Freiburg = University Medical Center Freiburg (Uniklinik), Sydney Children's hospital, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Howard Hughes Medical Institute [New York] (HHMI), Howard Hughes Medical Institute (HHMI)-New York University School of Medicine, Institut Pasteur [Paris]-CHU Necker - Enfants Malades [AP-HP], Beziat, Vivien, Li, Juan, Lin, Jian-Xin, Ma, Cindy S., Li, Peng, Bousfiha, Aziz, Pellier, Isabelle, Zoghi, Samaneh, Baris, Safa, Keles, Sevgi, Gray, Paul, Du, Ning, Wang, Yi, Zerbib, Yoann, Levy, Romain, Leclercq, Thibaut, About, Fredegonde, Lim, Ai Ing, Rao, Geetha, Payne, Kathryn, Pelham, Simon J., Avery, Danielle T., Deenick, Elissa K., Pillay, Bethany, Chou, Janet, Guery, Romain, Belkadi, Aziz, Guerin, Antoine, Migaud, Melanie, Rattina, Vimel, Ailal, Fatima, Benhsaien, Ibtihal, Bouaziz, Matthieu, Habib, Tanwir, Chaussabel, Damien, Marr, Nico, El-Benna, Jamel, Grimbacher, Bodo, Wargon, Orli, Bustamante, Jacinta, Boisson, Bertrand, Mueller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Chandesris, Marie-Olivia, Titeux, Matthias, Fraitag, Sylvie, Alyanakian, Marie-Alexandra, Leruez-Ville, Marianne, Picard, Capucine, Meyts, Isabelle, Di Santo, James P., Hovnanian, Alain, Somer, Ayper, Ozen, Ahmet, Rezaei, Nima, Chatila, Talal A., Abel, Laurent, Leonard, Warren J., Tangye, Stuart G., Puel, Anne, Casanova, Jean-Laurent

المصدر: Science Immunology
Science Immunology, American Association for the Advancement of Science, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩
Science Immunology, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩

مصطلحات موضوعية: 0301 basic medicine, INBORN-ERRORS, Immunoglobulin E, MESH: STAT3 Transcription Factor/immunology, Loss of heterozygosity, PRECISION MEDICINE, Transcription (biology), OF-FUNCTION MUTATIONS, STAT3, MESH: Transcription Factors/metabolism, CELL-DIFFERENTIATION, MESH: Th2 Cells/metabolism, MESH: Immunoglobulin E/immunology, MESH: Middle Aged, MESH: Gene Expression Regulation/immunology, Cell Differentiation, General Medicine, MESH: RNA, Messenger/metabolism, MESH: Immunoglobulin E/blood, MESH: Zinc Fingers/genetics, READ ALIGNMENT, MESH: Transcription, Genetic/immunology, MESH: Cell Nucleus/metabolism, MESH: Young Adult, [SDV.IMM]Life Sciences [q-bio]/Immunology, SIGNAL TRANSDUCER, Job Syndrome, MESH: Homozygote, STAT3 Transcription Factor, Cell type, MESH: Lymphocyte Count, MESH: Pedigree, MESH: STAT3 Transcription Factor/genetics, Immunology, Biology, Article, MESH: Job Syndrome/immunology, MESH: Genes, Recessive/genetics, DIFFERENTIAL EXPRESSION, MESH: Genes, Recessive/immunology, MESH: Job Syndrome/blood, MESH: Transcription Factors/genetics, 03 medical and health sciences, MESH: Whole Exome Sequencing, MESH: Exons/genetics, Humans, Transcription factor, Gene, MESH: Adolescent, MESH: Consanguinity, MESH: Humans, CLINICAL-FEATURES, MESH: Th17 Cells/metabolism, MESH: Th17 Cells/immunology, MESH: Cytokines/immunology, MESH: Adult, MESH: Loss of Function Mutation, MESH: Job Syndrome/genetics, MESH: Cell Differentiation/genetics, Molecular biology, MESH: Male, MESH: Th2 Cells/immunology, IL-21 RECEPTOR, 030104 developmental biology, Gene Expression Regulation, MESH: STAT3 Transcription Factor/metabolism, MESH: Promoter Regions, Genetic/genetics, MESH: Cell Differentiation/immunology, T-CELLS, STAT protein, biology.protein, Th17 Cells, MESH: Transcription Factors/immunology, MESH: Cytokines/metabolism, MESH: Female

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a014e03bf19bbdfb4eb205a53e190a3aTest
https://doi.org/10.1126/sciimmunol.aat4956Test

المؤلفون: Sébastien Fleury, Severine Navarro, Nicolas Glaichenhaus, A Kanda, David Dombrowicz, Anne Lazzari, Valérie Julia

المساهمون: Immunologie des muqueuses et inflammation, Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Institut de pharmacologie moléculaire et cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA), Récepteurs nucléaires, maladies cardiovasculaires et diabète - U 1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by a grant from the Fondation pour la Recherche Médicale and INSERM. S.N. was supported by a fellowship from the FRM, A.L. was supported by a fellowship from Vaincre la Mucoviscidose, and A.K is supported by a grant from the Agence Nationale de la Recherche (ANR)., We thank Nicolas Guy and the animal facility staff for their excellent animal care, as well as Julie Cazareth for the cell sorting experiments., Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Derudas, Marie-Hélène

المصدر: Mucosal Immunology
Mucosal Immunology, Nature Pub. Group, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩
Mucosal Immunology, 2015, 8 (4), pp.841-851. ⟨10.1038/mi.2014.115⟩

مصطلحات موضوعية: immune tolerance, T reg, medicine.medical_treatment, Protozoan Proteins, MESH: Ovalbumin/administration & dosage, MESH: Asthma/immunology, airway inflammation, Lymphocyte Activation, medicine.disease_cause, Immunoglobulin E, T-Lymphocytes, Regulatory, Mice, Th2, 0302 clinical medicine, Allergen, MESH: Antigens, Protozoan/immunology, Immunology and Allergy, CTLA-4 Antigen, MESH: Animals, IL-2 receptor, Desensitization (medicine), MESH: Immunoglobulin E/immunology, MESH: Th2 Cells/metabolism, 0303 health sciences, MESH: T-Lymphocytes, Regulatory/immunology, biology, respiratory system, MESH: Ovalbumin/immunology, MESH: Respiratory Hypersensitivity/metabolism, MESH: CTLA-4 Antigen/metabolism, 3. Good health, MESH: T-Lymphocytes, Regulatory/metabolism, [SDV.IMM]Life Sciences [q-bio]/Immunology, Bronchoalveolar Lavage Fluid, specific immunotherapy, MESH: Respiratory Hypersensitivity/immunology, MESH: Desensitization, Immunologic*/methods, [SDV.IMM] Life Sciences [q-bio]/Immunology, Ovalbumin, MESH: Mice, Transgenic, Immunology, MESH: Asthma/metabolism, Antigens, Protozoan, Mice, Transgenic, Article, Inducible T-Cell Co-Stimulator Protein, 03 medical and health sciences, Th2 Cells, MESH: Inducible T-Cell Co-Stimulator Protein/metabolism, Antigen, In vivo, MESH: Allergens/administration & dosage, Respiratory Hypersensitivity, medicine, Animals, MESH: Mice, 030304 developmental biology, business.industry, MESH: Interleukin-2 Receptor alpha Subunit/metabolism, Interleukin-2 Receptor alpha Subunit, Immunotherapy, Allergens, asthma, MESH: Protozoan Proteins/immunology, MESH: Lymphocyte Activation/immunology, MESH: Th2 Cells/immunology, respiratory tract diseases, MESH: Respiratory Hypersensitivity/therapy, Disease Models, Animal, Desensitization, Immunologic, MESH: Bronchoalveolar Lavage Fluid/immunology, biology.protein, MESH: Allergens/immunology, MESH: Disease Models, Animal, business, MESH: Asthma/therapy, 030215 immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d213c53e8f68090bfc11e41706a54bTest
https://doi.org/10.1038/mi.2014.115Test

المؤلفون: Sebastian Amigorena, Paola Romagnoli, Agathe Malbec, Véronique Adoue, Joost P.M. van Meerwijk, Olivier Joffre, Joanna Fourquet, Bénédicte Binet

المساهمون: Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Immunité et cancer (U932), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014), CCSD, Accord Elsevier, Appel à projets générique - Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome - - EpiTreg2014 - ANR-14-CE14-0021 - Appel à projets générique - VALID, Université Fédérale Toulouse Midi-Pyrénées, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Curie [Paris]

المصدر: Immunity
Immunity, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩
Immunity, Elsevier, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: CD4-Positive T-Lymphocytes / immunology, CD4-Positive T-Lymphocytes, Male, Cellular differentiation, Endogenous retrovirus, Priming (immunology), MESH: Endogenous Retroviruses / immunology, lineage commitment, H3K9me3, Th1, MESH: Th2 Cells / immunology, Histones, Mice, 0302 clinical medicine, SETDB1, Immunology and Allergy, MESH: Animals, Promoter Regions, Genetic, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], histone methyltransferase, Cell Differentiation, T helper cell, T-Lymphocytes, Helper-Inducer, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Cell biology, Infectious Diseases, medicine.anatomical_structure, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, 030220 oncology & carcinogenesis, Histone methyltransferase, [SDV.IMM.IA] Life Sciences [q-bio]/Immunology/Adaptive immunology, Histone Methyltransferases, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Female, transposable elements, MESH: Histone Methyltransferases / immunology, MESH: Cell Differentiation / immunology, MESH: Histones / immunology, ERV, Immunology, Biology, MESH: Th1 Cells / immunology, 03 medical and health sciences, Th2 Cells, ESET, MESH: Mice, Inbred C57BL, MESH: Promoter Regions, Genetic / immunology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Animals, Cell Lineage, Enhancer, Gene, MESH: Mice, Endogenous Retroviruses, Promoter, Histone-Lysine N-Methyltransferase, Th1 Cells, MESH: Male, Mice, Inbred C57BL, 030104 developmental biology, exaptation, MESH: T-Lymphocytes, Helper-Inducer / immunology, MESH: Histone-Lysine N-Methyltransferase / immunology, MESH: Female, MESH: Cell Lineage / immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a10471dc12184df5235014b4cd16d9Test
https://pubmed.ncbi.nlm.nih.gov/30893582Test

المؤلفون: Schülke, S., Flaczyk, A., Vogel, L., Gaudenzio, N., Angers, I., Löschner, B., Wolfheimer, S., Spreitzer, I., Qureshi, S., Tsai, M., Galli, S., Vieths, S., Scheurer, S.

المساهمون: Paul-Ehrlich-Institute - Federal Institute for Vaccines and Biomedicines (EPI), Stanford University, McGill University Health Center Montreal (MUHC), German Research Foundation (DFG SCHU2951/1-1, SCHE637/3)

المصدر: ISSN: 0105-4538.

مصطلحات موضوعية: adjuvant, allergy, lipopolysaccharide, mast cells, monophosphoryl lipid A, MESH: Adaptor Proteins, Vesicular Transport / genetics, Vesicular Transport / metabolism, MESH: Monocytes / immunology, MESH: Monocytes / metabolism, MESH: Disease Models, Animal, MESH: Shock, Septic / genetics, Septic / immunology, Septic / metabolism, MESH: Antigens / immunology, MESH: Th2 Cells / immunology, MESH: Th2 Cells / metabolism, MESH: B-Lymphocytes / immunology, MESH: Lipopolysaccharides / pharmacology, MESH: B-Lymphocytes / metabolism, MESH: Cytokines / biosynthesis, MESH: Dendritic Cells / drug effects, MESH: Epithelial Cells / metabolism, MESH: Dendritic Cells / immunology, MESH: Dendritic Cells / metabolism, MESH: Humans, MESH: Inflammation Mediators / metabolism, MESH: Lipid A / analogs & derivatives

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26081583; hal-03479685; https://ut3-toulouseinp.hal.science/hal-03479685Test; PUBMED: 26081583

الإتاحة: https://doi.org/10.1111/all.12675Test
https://ut3-toulouseinp.hal.science/hal-03479685Test

المؤلفون: Isabelle Angers, Stephen J. Galli, Adam Flaczyk, Salman T. Qureshi, Lothar Vogel, Ingo Spreitzer, Nicolas Gaudenzio, Sonja Wolfheimer, Stefan Schülke, B. Löschner, Mindy Tsai, Stephan Scheurer, Stefan Vieths

المساهمون: Paul-Ehrlich-Institute - Federal Institute for Vaccines and Biomedicines (EPI), Stanford University, McGill University Health Center [Montreal] (MUHC), German Research Foundation (DFG SCHU2951/1-1, SCHE637/3)

المصدر: Allergy
Allergy, Wiley, 2015, 70 (10), pp.1259-1268. ⟨10.1111/all.12675⟩

مصطلحات موضوعية: Lipopolysaccharides, Lipopolysaccharide, medicine.medical_treatment, Monophosphoryl Lipid A, MESH: Lipopolysaccharides / pharmacology, MESH: Mast Cells / metabolism, MESH: Monocytes / immunology, MESH: Dendritic Cells / drug effects, MESH: Mice, Knockout, Monocytes, MESH: Th2 Cells / immunology, chemistry.chemical_compound, Mice, Immunology and Allergy, MESH: Animals, Mast Cells, [SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology, MESH: Dendritic Cells / metabolism, MESH: Lipid A / analogs & derivatives, Mice, Knockout, B-Lymphocytes, lipopolysaccharide, MESH: Mast Cells / drug effects, MESH: Inflammation Mediators / metabolism, Shock, Septic, MESH: Mast Cells / immunology, 3. Good health, MESH: B-Lymphocytes / immunology, MESH: B-Lymphocytes / metabolism, medicine.anatomical_structure, Lipid A, MESH: Epithelial Cells / metabolism, MESH: Adaptor Proteins, Vesicular Transport / genetics, MESH: Lipopolysaccharides / immunology, [SDV.IMM]Life Sciences [q-bio]/Immunology, Cytokines, MESH: Dendritic Cells / immunology, Inflammation Mediators, MESH: Shock, Septic / immunology, MESH: Antigens / immunology, Immunology, monophosphoryl lipid A, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, MESH: Monocytes / drug effects, Immune system, Th2 Cells, adjuvant, MESH: Monocytes / metabolism, MESH: Adaptor Proteins, Vesicular Transport / metabolism, medicine, Animals, Humans, Secretion, MESH: Shock, Septic / metabolism, Antigens, MESH: Mice, MESH: Lipid A / immunology, MESH: Humans, MESH: Th2 Cells / metabolism, Monocyte, Epithelial Cells, Immunotherapy, Dendritic Cells, allergy, MESH: Lipid A / pharmacology, Adaptor Proteins, Vesicular Transport, Disease Models, Animal, chemistry, TLR4, MESH: Cytokines / biosynthesis, Cytokine secretion, MESH: Disease Models, Animal, MESH: Shock, Septic / genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead28381c905416c0cb2ec75c2a88011Test
https://pubmed.ncbi.nlm.nih.gov/26081583Test

المؤلفون: Moralès, Olivier, Mrizak, Dhafer, François, Violaine, Mustapha, Rami, Miroux, Céline, Depil, Stephane, Decouvelaere, Anne-Valérie, Lionne-Huyghe, Pauline, Auriault, Claude, de Launoit, Yvan, Pancré, Véronique, Delhem, Nadira

المساهمون: Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Université libre de Bruxelles (ULB), Service des Maladies du Sang CHU Lille (SMS), Hôpital Claude Huriez Lille, Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Université de Lille-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Université de Lille-Université de Lille, Département d'hématologie Gustave Roussy, Institut Gustave Roussy (IGR), Institut de Pathologie CHU Lille, Pôle de Biologie Pathologie Génétique CHU Lille, Unité Fonctionnelle d’Anatomie et de Cytologie Pathologiques Lyon, Département d'anatomopathologie, biopathologie, Centre Léon Bérard Lyon -Centre Léon Bérard Lyon, Groupe Hospitalier Artois-Ternois Centre Hospitalier d’Arras, Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS), Université de Lille, Sciences et Technologies, This work received financial supports from the ‘Association de Recherche contre le Cancer’, the ‘Fondation de Recherche Médical’, OSEO and the Nord‐Pas‐de Calais Region. This work was also supported by SIRIC ONCOLille., The authors would like to thank Han VORNG for his technical assistance.

المصدر: ISSN: 0007-1048.

مصطلحات موضوعية: Tr1, chemokines, Epstein-Barr Virus, Hodgkin lymphoma, IL10, MESH: Adolescent, MESH: Adult, MESH: Th2 Cells/immunology, MESH: Th2 Cells/virology, MESH: Aged, MESH: Up-Regulation, MESH: Young Adult, MESH: Biomarkers/metabolism, MESH: Chemokines/metabolism, MESH: Child, MESH: Cytokines/metabolism, MESH: Epstein-Barr Virus Infections/immunology, MESH: Hodgkin Disease/immunology, MESH: Female, MESH: Gene Expression Regulation, Neoplastic, MESH: Hodgkin Disease/virology, MESH: Humans, MESH: Male, MESH: Middle Aged, MESH: Phenotype, MESH: T-Lymphocytes, Regulatory/immunology, Regulatory/virology, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25041527; hal-02395755; https://hal.science/hal-02395755Test; PUBMED: 25041527

الإتاحة: https://doi.org/10.1111/bjh.12980Test
https://hal.science/hal-02395755Test

المؤلفون: Olivier Moralès, Anne-Valérie Decouvelaere, Violaine François, Stéphane Depil, Claude Auriault, Véronique Pancré, Rami Mustapha, Nadira Delhem, Céline Miroux, Dhafer Mrizak, Yvan de Launoit, Pauline Lionne-Huyghe

المساهمون: Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Université libre de Bruxelles (ULB), Service des Maladies du Sang [CHRU Lille], Hôpital Claude Huriez [Lille], CHU Lille-CHU Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Département d'hématologie [Gustave Roussy], Institut Gustave Roussy (IGR), Institut de Pathologie [CHU Lille], Pôle de Biologie Pathologie Génétique [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Unité Fonctionnelle d’Anatomie et de Cytologie Pathologiques [Lyon], Département d'anatomopathologie, biopathologie, Centre Léon Bérard [Lyon]-Centre Léon Bérard [Lyon], Groupe Hospitalier Artois-Ternois Centre Hospitalier d’Arras, Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS), Université de Lille, Sciences et Technologies, This work received financial supports from the ‘Association de Recherche contre le Cancer’, the ‘Fondation de Recherche Médical’, OSEO and the Nord‐Pas‐de Calais Region. This work was also supported by SIRIC ONCOLille., The authors would like to thank Han VORNG for his technical assistance.

المصدر: British Journal of Haematology
British Journal of Haematology, Wiley, 2014, 166 (6), pp.875-890. ⟨10.1111/bjh.12980⟩

مصطلحات موضوعية: Male, Chemokine, Epstein-Barr Virus Infections, LAG3, [SDV]Life Sciences [q-bio], medicine.disease_cause, T-Lymphocytes, Regulatory, hemic and lymphatic diseases, MESH: Child, MESH: Up-Regulation, MESH: Chemokines/metabolism, MESH: Hodgkin Disease/virology, Child, MESH: Aged, MESH: Middle Aged, biology, MESH: Th2 Cells/virology, Hematology, MESH: Gene Expression Regulation, Neoplastic, Middle Aged, Hodgkin Disease, 3. Good health, Up-Regulation, Gene Expression Regulation, Neoplastic, Interleukin 10, Phenotype, MESH: Young Adult, Cytokines, Female, MESH: T-Lymphocytes, Regulatory/virology, Chemokines, Epstein-Barr Virus, Adult, Adolescent, MESH: Phenotype, Peripheral blood mononuclear cell, Tr1, Young Adult, Immune system, Th2 Cells, medicine, MESH: Hodgkin Disease/immunology, Humans, Epstein–Barr virus infection, Aged, MESH: Adolescent, MESH: Humans, MESH: Epstein-Barr Virus Infections/immunology, MESH: Biomarkers/metabolism, MESH: T-Lymphocytes, Regulatory/immunology, MESH: Adult, medicine.disease, Epstein–Barr virus, MESH: Male, MESH: Th2 Cells/immunology, CTL, Immunology, biology.protein, MESH: Cytokines/metabolism, MESH: Female, Hodgkin lymphoma, Biomarkers, IL10

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1379756aab8bae4f2a0ec70d388160Test
https://pubmed.ncbi.nlm.nih.gov/25041527Test