المؤلفون: Weulersse, Marianne, Asrir, Assia, Pichler, Andrea, C, Lemaitre, Lea, Braun, Matthias, Carrié, Nadège, Joubert, Marie-Véronique, Le Moine, Marie, Do Souto, Laura, Gaud, Guillaume, Das, Indrajit, Brauns, Elisa, Scarlata, Clara, M, Morandi, Elena, Sundarrajan, Ashmitha, Cuisinier, Marine, Buisson, Laure, Maheo, Sabrina, Kassem, Sahar, Agesta, Arantxa, Pérès, Michaël, Verhoeyen, Els, Martinez, Alejandra, Mazière, Julien, Dupré, Loïc, Gossye, Thomas, Pancaldi, Vera, Guillerey, Camille, Ayyoub, Maha, Dejean, Anne, Saoudi, Abdelhadi, Goriely, Stanislas, Avet-Loiseau, Hervé, Bald, Tobias, Smyth, Mark, J, Martinet, Ludovic

المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), QIMR Berghofer Medical Research Institute, Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université libre de Bruxelles (ULB), Centre de Physiopathologie Toulouse Purpan (CPTP), Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), Barcelona Supercomputing Center - Centro Nacional de Supercomputacion (BSC-CNS)

المصدر: ISSN: 1074-7613 ; Immunity ; https://hal.science/hal-03030829Test ; Immunity, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩.

مصطلحات موضوعية: 8 Figures, 8 Supplementary Figures, 96 References CD8 + T lymphocytes, TCR signaling, Co-stimulation, CD226 (DNAM-1), tumor immune escape, T cell exhaustion, Immunotherapy, immune checkpoint blockade, MESH: Animals, MESH: Antigens, Differentiation, T-Lymphocyte / immunology, MESH: Programmed Cell Death 1 Receptor / immunology, MESH: Receptors, Antigen, T-Cell / immunology, MESH: Signal Transduction / immunology, MESH: T-Box Domain Proteins / immunology, MESH: Transcriptome / immunology, MESH: Tumor Microenvironment / immunology, MESH: Tumor Necrosis Factor Receptor Superfamily, Member 9 / immunology, MESH: CD8-Positive T-Lymphocytes / immunology, MESH: Humans, MESH: Immune Checkpoint Inhibitors / immunology, MESH: Immunotherapy / methods, MESH: Mice, Inbred C57BL

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33053331; hal-03030829; https://hal.science/hal-03030829Test; https://hal.science/hal-03030829/documentTest; https://hal.science/hal-03030829/file/CD226%20paper.pdfTest; PUBMED: 33053331

الإتاحة: https://doi.org/10.1016/j.immuni.2020.09.006Test
https://hal.science/hal-03030829Test
https://hal.science/hal-03030829/documentTest
https://hal.science/hal-03030829/file/CD226%20paper.pdfTest

المؤلفون: Grünvogel, Oliver, Colasanti, Ombretta, Lee, Ji-Young, Klöss, Volker, Belouzard, Sandrine, Reustle, Anna, Esser-Nobis, Katharina, Hesebeck-Brinckmann, Jasper, Mutz, Pascal, Hoffmann, Katrin, Mehrabi, Arianeb, Koschny, Ronald, Vondran, Florian W.R., Gotthardt, Daniel, Schnitzler, Paul, Neumann-Haefelin, Christoph, Thimme, Robert, Binder, Marco, Bartenschlager, Ralf, Dubuisson, Jean, Dalpke, Alexander, H, Lohmann, Volker

المساهمون: Universität Heidelberg Heidelberg = Heidelberg University, Department of Infectious Diseases Heidelberg, Germany, Heidelberg University Hospital Heidelberg, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), German Cancer Research Center - Deutsches Krebsforschungszentrum Heidelberg (DKFZ), Medizinische Hochschule Hannover = Hannover Medical School (MHH), German Center for Infection Research Heidelberg, Germany (DZIF), University Hospital Freiburg, Albert-Ludwigs-Universität Freiburg, This project was supported by grants from the Deutsche Forschungsgemeinschaft (TRR179-TP17, FOR1202-TP3 to Volker Lohmann, TRR179-TP9, FOR1202-TP1 to Ralf Bartenschlager, TRR179-TP1 to Robert Thimme, and TRR179-TP2 to Christoph Neumann-Haefelin). This work was supported by a grant from the Excellence Cluster Cellular Networks of University of Heidelberg (to Alexander H. Dalpke and Volker Lohmann)., The authors thank Rahel Klein, Ulrike Herian, Uta Haselmann, and Jutta Mohr for excellent technical assistance and Vibor Laketa for microscopy support. We are grateful to the Electron Microscopy Core Facility of the University of Heidelberg for providing access to their equipment and thanks to Dr Charlotta Funaya and Dr Stefan Hillmer for technical support in electron microscopy work. A plasmid encoding TLR3 was a kind gift from T. Espevik, NTNU, Trondheim, Norway. In addition, we thank Daniel Lamarre for helpful discussions.

المصدر: ISSN: 0016-5085.

مصطلحات موضوعية: Virology, Escape, Rab27a, Exosomes, MESH: Cell Line, MESH: Extracellular Vesicles/immunology, MESH: Hepacivirus/physiology, MESH: Hepatitis C, Chronic/blood, MESH: Humans, Chronic/immunology, Chronic/virology, MESH: Hepatocytes/immunology, MESH: Hepatocytes/metabolism, MESH: Host-Pathogen Interactions/immunology, MESH: Immunity, Innate, MESH: Interferons/immunology, MESH: RNA, Viral/immunology, MESH: Interferons/metabolism, MESH: Primary Cell Culture, Double-Stranded/immunology, Double-Stranded/isolation & purification, Double-Stranded/metabolism, Viral/isolation & purification, MESH: Extracellular Vesicles/metabolism, Viral/metabolism, MESH: Signal Transduction/immunology, MESH: Toll-Like Receptor 3/immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29535029; hal-02112499; https://hal.science/hal-02112499Test; https://hal.science/hal-02112499/documentTest; https://hal.science/hal-02112499/file/Lohmann-Gastro-2018.pdfTest; PUBMED: 29535029

الإتاحة: https://doi.org/10.1053/j.gastro.2018.03.020Test
https://hal.science/hal-02112499Test
https://hal.science/hal-02112499/documentTest
https://hal.science/hal-02112499/file/Lohmann-Gastro-2018.pdfTest

المؤلفون: Javed, Numan, Xue, Guang, Lu, Ailing, Xing, Yue, Iwakura, Yoichiro, Xiao, Hui, Lecoeur, Hervé, Späth, Gerald F, Meng, Guangxun

المساهمون: Key Laboratory of Molecular Virology and Immunology Shanghai, China, Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Division of Experimental Animal Immunology, Center for Animal Disease Models Japan, Tokyo University of Science Tokyo -Research Institute for Biomedical Sciences Japan, Parasitologie moléculaire et Signalisation / Molecular Parasitology and Signaling, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by grants from Natural Science Foundation of China (31370892, 31300712, 91429307, 31570895), National Key Basic Research Programs (2014CB541905, 2015CB554302) and National Major Projects for Science and Technology (2014ZX0801011B-001).

المصدر: ISSN: 1043-4666.

مصطلحات موضوعية: TNF-α, S. aureus, Inflammasome, IL-1β, Cross reactivity, MESH: Animals, MESH: Blotting, Western, MESH: Mice, Knockout, MESH: Signal Transduction/genetics, MESH: Staphylococcus aureus/classification, MESH: Signal Transduction/immunology, MESH: Species Specificity, MESH: Staphylococcus aureus/genetics, MESH: Cells, Cultured, MESH: Staphylococcus aureus/immunology, MESH: Tumor Necrosis Factor-alpha/immunology, MESH: Cross Reactions/immunology, MESH: Enzyme-Linked Immunosorbent Assay/methods, MESH: Cytokines/genetics, MESH: Cytokines/immunology, MESH: Host-Pathogen Interactions/immunology, MESH: Macrophages/immunology, MESH: Interleukin-1beta/genetics, MESH: Interleukin-1beta/immunology, MESH: Macrophages/metabolism, MESH: Macrophages/microbiology, Inbred C57BL

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26978550; pasteur-01441010; https://pasteur.hal.science/pasteur-01441010Test; https://pasteur.hal.science/pasteur-01441010/documentTest; https://pasteur.hal.science/pasteur-01441010/file/Manuscript_Cytokine_Cross_reactivity.pdfTest; PUBMED: 26978550

الإتاحة: https://doi.org/10.1016/j.cyto.2016.03.007Test
https://pasteur.hal.science/pasteur-01441010Test
https://pasteur.hal.science/pasteur-01441010/documentTest
https://pasteur.hal.science/pasteur-01441010/file/Manuscript_Cytokine_Cross_reactivity.pdfTest

المؤلفون: Stanislas Goriely, Marie-Véronique Joubert, Tobias Bald, Mark J. Smyth, Ludovic Martinet, Elena Morandi, Loïc Dupré, Laure Buisson, Nadège Carrié, Marianne Weulersse, Guillaume Gaud, Marie Le Moine, Thomas Gossye, Anne Dejean, Hervé Avet-Loiseau, Ashmitha Sundarrajan, Assia Asrir, Andrea C. Pichler, Michaël Pérès, Abdelhadi Saoudi, Alejandra Martinez, Julien Mazieres, Sahar Kassem, Elisa Brauns, Els Verhoeyen, Indrajit Das, Sabrina Maheo, Matthias Braun, Vera Pancaldi, Clara Maria Scarlata, Marine Cuisinier, Maha Ayyoub, Laura Do Souto, Lea Lemaitre, Arantxa Agesta, Camille Guillerey

المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), QIMR Berghofer Medical Research Institute, Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université libre de Bruxelles (ULB), Centre de Physiopathologie Toulouse Purpan (CPTP), Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Centre International de Recherche en Infectiologie - UMR (CIRI), Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases (LBI-RUD), Barcelona Supercomputing Center - Centro Nacional de Supercomputacion (BSC - CNS), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Nice Sophia Antipolis (1965 - 2019) (UNS), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Physiopathologie Toulouse Purpan ex IFR 30 et IFR 150 (CPTP)

المصدر: Immunity, 53 (4
Immunity
Immunity, Elsevier, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩
Immunity, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Neoplasms / immunology, 8 Supplementary Figures, Lymphocyte, medicine.medical_treatment, [SDV]Life Sciences [q-bio], MESH: Programmed Cell Death 1 Receptor / immunology, CD226 (DNAM-1), MESH: Receptors, Antigen, T-Cell / immunology, MESH: Neoplasms / therapy, TCR signaling, 0302 clinical medicine, Cancer immunotherapy, MESH: Tumor Necrosis Factor Receptor Superfamily, Member 9 / immunology, Immunology and Allergy, Cytotoxic T cell, MESH: Animals, ComputingMilieux_MISCELLANEOUS, T cell exhaustion, MESH: Signal Transduction / immunology, MESH: CD8-Positive T-Lymphocytes / immunology, 3. Good health, Infectious Diseases, medicine.anatomical_structure, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, 030220 oncology & carcinogenesis, Immunotherapy, MESH: Transcriptome / immunology, Immunology, Eomesodermin, 8 Figures, Biology, MESH: Antigens, Differentiation, T-Lymphocyte / immunology, Co-stimulation, 03 medical and health sciences, tumor immune escape, MESH: Mice, Inbred C57BL, MESH: Immune Checkpoint Inhibitors / immunology, medicine, MESH: Tumor Microenvironment / immunology, MESH: Mice, 96 References CD8 + T lymphocytes, Tumor microenvironment, MESH: Humans, immune checkpoint blockade, MESH: T-Box Domain Proteins / immunology, Immune checkpoint, MESH: Immunotherapy / methods, Sciences biomédicales, 030104 developmental biology, Cancer research, CD8

وصف الملف: 1 full-text file(s): application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfe5be6f45852b02f2ba60ac27610faTest
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/316003Test

المؤلفون: Mindy Tsai, Nicolas Gaudenzio, Axel Roers, See-Ying Tam, Yuko Kawakami, Pierre Chambon, Philipp Starkl, Dimitri Pirottin, Stephen J. Galli, Sophie El Abbas, Jinah Kim, Nadine Antoine, Fabrice Bureau, Oliwia W Zurek, Laurent L. Reber, Toshiaki Kawakami, Thomas Marichal, Riccardo Sibilano

المساهمون: Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA-Research), Université de Liège, Department of Pathology [Stanford], Stanford Medicine, Stanford University-Stanford University, Sean N. Parker Center for Allergy and Asthma Research [Stanford], Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Technische Universität Dresden = Dresden University of Technology (TU Dresden), Cell and Developmental Biology [San Diego], School of Biological Sciences [Univ California San Diego] (UC San Diego), University of California [San Diego] (UC San Diego), University of California (UC)-University of California (UC)-University of California [San Diego] (UC San Diego), University of California (UC)-University of California (UC), Environmental Molecular Biology Laboratory (RIKEN), RIKEN - Institute of Physical and Chemical Research [Japon] (RIKEN), Walloon Excellence in Life sciences and BIOtechnology [Liège] (WELBIO), Stanford School of Medicine [Stanford], Department of Microbiology and Immunology [Stanford], Pistre, Karine

المصدر: Journal of Clinical Investigation
Journal of Clinical Investigation, 2016, 126 (12), pp.4497-4515. ⟨10.1172/JCI86359⟩

مصطلحات موضوعية: Keratinocytes, 0301 basic medicine, MESH: Guanine Nucleotide Exchange Factors / genetics, [SDV]Life Sciences [q-bio], MESH: Myeloid Differentiation Factor 88 / immunology, MESH: Dermatitis, Contact / immunology, Dermatitis, Contact, MESH: Mice, Knockout, Mice, 0302 clinical medicine, MESH: Humans Keratinocytes / immunology, Guanine Nucleotide Exchange Factors, MESH: Animals, MESH: NF-kappa B / genetics, Mice, Knockout, MESH: Dermatitis, Contact / pathology, integumentary system, MESH: Signal Transduction / immunology, MESH: Guanine Nucleotide Exchange Factors / immunology, Chemistry, NF-kappa B, MESH: Epidermis / pathology, General Medicine, Atopic dermatitis, Phenotype, Cell biology, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, MESH: NF-kappa B / immunology, 030220 oncology & carcinogenesis, MESH: Dermatitis, Contact / genetics, [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, Guanine nucleotide exchange factor, MESH: Signal Transduction / genetics Signal Transduction / immunology, Signal transduction, medicine.symptom, Keratinocyte, Signal Transduction, Research Article, [SDV.IMM] Life Sciences [q-bio]/Immunology, Inflammation, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, 03 medical and health sciences, MESH: Keratinocytes / pathology, medicine, Animals, Humans, MESH: Receptors, Interleukin-1 Type I / immunology, MESH: Mice, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Allergic contact dermatitis, Receptors, Interleukin-1 Type I, medicine.disease, 030104 developmental biology, Myeloid Differentiation Factor 88, Rab, Epidermis, MESH: Receptors, Interleukin-1 Type I / genetics, MESH: Female, MESH: Myeloid Differentiation Factor 88 / genetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542066fd135b8c7de9d713b77f413dc3Test
https://doi.org/10.1172/jci86359Test

المؤلفون: Marichal, Thomas, Gaudenzio, Nicolas, El Abbas, Sophie, Sibilano, Riccardo, Zurek, Oliwia, Starkl, Philipp, Reber, Laurent, Pirottin, Dimitri, Kim, Jinah, Chambon, Pierre, Roers, Axel, Antoine, Nadine, Kawakami, Yuko, Kawakami, Toshiaki, Bureau, Fabrice, Tam, See-Ying, Tsai, Mindy, Galli, Stephen

المساهمون: Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA-Research), Université de Liège, Department of Pathology Stanford, Stanford Medicine, Stanford University-Stanford University, Sean N. Parker Center for Allergy and Asthma Research Stanford, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Technische Universität Dresden = Dresden University of Technology (TU Dresden), Cell and Developmental Biology San Diego, School of Biological Sciences Univ California San Diego (UC San Diego), University of California San Diego (UC San Diego), University of California (UC)-University of California (UC)-University of California San Diego (UC San Diego), University of California (UC)-University of California (UC), Environmental Molecular Biology Laboratory (RIKEN), RIKEN - Institute of Physical and Chemical Research Japon (RIKEN), Walloon Excellence in Life sciences and BIOtechnology Liège (WELBIO), Stanford School of Medicine Stanford, Department of Microbiology and Immunology Stanford

المصدر: ISSN: 0021-9738 ; Journal of Clinical Investigation ; https://ut3-toulouseinp.hal.science/hal-03532912Test ; Journal of Clinical Investigation, 2016, 126 (12), pp.4497-4515. ⟨10.1172/JCI86359⟩.

مصطلحات موضوعية: MESH: Animals, MESH: Dermatitis, Contact / genetics, MESH: Mice, Knockout, MESH: Myeloid Differentiation Factor 88 / genetics, MESH: Myeloid Differentiation Factor 88 / immunology, MESH: NF-kappa B / genetics, MESH: NF-kappa B / immunology, MESH: Receptors, Interleukin-1 Type I / genetics, Interleukin-1 Type I / immunology, MESH: Signal Transduction / genetics Signal Transduction / immunology, MESH: Signal Transduction / immunology, Contact / immunology, Contact / pathology, MESH: Epidermis / pathology, MESH: Female, MESH: Guanine Nucleotide Exchange Factors / genetics, MESH: Guanine Nucleotide Exchange Factors / immunology, MESH: Humans Keratinocytes / immunology, MESH: Keratinocytes / pathology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27820702; hal-03532912; https://ut3-toulouseinp.hal.science/hal-03532912Test; PUBMED: 27820702; PUBMEDCENTRAL: PMC5127679

الإتاحة: https://doi.org/10.1172/JCI86359Test
https://ut3-toulouseinp.hal.science/hal-03532912Test

المؤلفون: Hui Xiao, Numan Javed, Guang Xue, Guangxun Meng, Yue Xing, Gerald F. Späth, Ailing Lu, Yoichiro Iwakura, Hervé Lecoeur

المساهمون: Key Laboratory of Molecular Virology and Immunology [Shanghai, China], Institut Pasteur de Shanghai, Académie des Sciences de Chine - Chinese Academy of Sciences (IPS-CAS), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Division of Experimental Animal Immunology, Center for Animal Disease Models [Japan], Tokyo University of Science [Tokyo]-Research Institute for Biomedical Sciences [Japan], Parasitologie moléculaire et Signalisation / Molecular Parasitology and Signaling, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by grants from Natural Science Foundation of China (31370892, 31300712, 91429307, 31570895), National Key Basic Research Programs (2014CB541905, 2015CB554302) and National Major Projects for Science and Technology (2014ZX0801011B-001)., Parasitologie moléculaire et Signalisation, Ricard Andraos, Christel, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Cytokine
Cytokine, Elsevier, 2016, 81, pp.101-108. ⟨10.1016/j.cyto.2016.03.007⟩
Cytokine, 2016, 81, pp.101-108. ⟨10.1016/j.cyto.2016.03.007⟩

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, MESH: Cytokines/genetics, MESH: Enzyme-Linked Immunosorbent Assay/methods, Interleukin-1beta, medicine.disease_cause, Biochemistry, Cross-reactivity, MESH: Mice, Knockout, Inflammasome, Immunology and Allergy, Medicine, MESH: Animals, MESH: Tumor Necrosis Factor-alpha/immunology, MESH: Signal Transduction/genetics, Cells, Cultured, Mice, Knockout, biology, MESH: Macrophages/immunology, Cross reactivity, MESH: Macrophages/microbiology, Hematology, MESH: Staphylococcus aureus/classification, MESH: Staphylococcus aureus/genetics, 3. Good health, Cytokine, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Staphylococcus aureus, IL-1β, MESH: Host-Pathogen Interactions/immunology, MESH: Cross Reactions/immunology, Host-Pathogen Interactions, Cytokines, Antibody, medicine.symptom, medicine.drug, MESH: Cells, Cultured, Signal Transduction, MESH: Interleukin-1beta/immunology, MESH: Interleukin-1beta/genetics, Gram-positive bacteria, Immunology, Blotting, Western, Inflammation, Enzyme-Linked Immunosorbent Assay, Cross Reactions, 03 medical and health sciences, Immune system, Species Specificity, MESH: Mice, Inbred C57BL, MESH: Blotting, Western, MESH: Species Specificity, Animals, MESH: Macrophages/metabolism, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, Molecular Biology, business.industry, Tumor Necrosis Factor-alpha, Macrophages, MESH: Cytokines/immunology, MESH: Signal Transduction/immunology, biology.organism_classification, S. aureus, Mice, Inbred C57BL, 030104 developmental biology, TNF-α, biology.protein, business, MESH: Staphylococcus aureus/immunology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87936c8a3631d257b3429a962b4524efTest
https://pubmed.ncbi.nlm.nih.gov/26978550Test

المؤلفون: Laurent Boyer, Emmanuel Lemichez

المساهمون: Toxines bactériennes dans la relation hôtes-pathogènes, Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR50-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Our laboratory is supported by INSERM, Ligue Nationale contre le Cancer, the French Government (National Research Agency, ANR) through the 'Investments for the Future' LABEX SIGNALIFE ANR-11-LABX-0028–01 and ANR-11-BSV3–004–01, Fondation ARC pour la Recherche sur le Cancer (ARC 3800, RAC13006AAA)., ANR-11-LABX-0028,SIGNALIFE,Réseau d'Innovation sur les Voies de Signalisation en Sciences de la Vie(2011)

المصدر: Small GTPases
Small GTPases, Taylor & Francis, 2015, 6 (4), pp.186-188. ⟨10.1080/21541248.2015.1095698⟩

مصطلحات موضوعية: [SDV]Life Sciences [q-bio], Interleukin-1beta, caspase-1, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], medicine.disease_cause, Biochemistry, Hemolysin Proteins, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB], MESH: Animals, Pathogen, innate immunity, Escherichia coli Infections, MESH: Signal Transduction/immunology, MESH: Escherichia coli/immunology, rho-Associated Kinases, MESH: Escherichia coli/pathogenicity, Escherichia coli Proteins, Caspase 1, bacterial effectors, 3. Good health, Cell biology, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: Escherichia coli Proteins/immunology, MESH: Bacterial Toxins/immunology, Signal Transduction, MESH: Escherichia coli Infections/pathology, antibacterial defenses, MESH: Escherichia coli Infections/immunology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, MESH: Caspase 1/immunology, Immune system, Il-1beta, effector-triggered immunity, medicine, Escherichia coli, Animals, Humans, bacterial toxins, Innate immune system, MESH: Humans, Toxin, Mechanism (biology), Pathogenic bacteria, Cell Biology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, MESH: Interleukin-1beta/immunology, Commentary, MESH: Hemolysin Proteins/immunology, Effector-triggered immunity, MESH: rho-Associated Kinases/immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17226ee95ed7313fefd5e1788a5eccbTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-02448674Test

المؤلفون: Isabelle Bouvier, James P. Di Santo, Matthew L. Albert, Jacques Deguine, Hélène Beuneu, Philippe Bousso

المساهمون: Dynamiques des Réponses Immunes, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunobiologie des Cellules Dendritiques, Immunité Innée, This work was supported by the Institut Pasteur, INSERM, the European Research Council, Mairie de Paris, and a Marie-Curie Excellence grant. H.B. is supported by the Fondation pour la Recherche Me´dicale. M.L.A. is supported by the Ligue contre le Cancer and a European Research Council award., Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Journal of Immunology
Journal of Immunology, 2011, 187 (5), pp.2084-8. ⟨10.4049/jimmunol.1004210⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2011, 187 (5), pp.2084-8. ⟨10.4049/jimmunol.1004210⟩

مصطلحات موضوعية: Adoptive cell transfer, Interferon Inducers, MESH: Interferon Inducers/immunology, Immunology, MESH: Killer Cells, Natural/immunology, Priming (immunology), MESH: Flow Cytometry, Cell Separation, Biology, Lymphocyte Activation, MESH: Cell Separation, MESH: Interferon Type I/immunology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Interleukin 21, 0302 clinical medicine, MESH: Mice, Inbred C57BL, MESH: Poly I-C/immunology, Animals, Immunology and Allergy, Cytotoxic T cell, MESH: Animals, MESH: Mice, 030304 developmental biology, MESH: Signal Transduction/immunology, Interleukin-15, 0303 health sciences, Lymphokine-activated killer cell, Janus kinase 3, MESH: Lymphocyte Activation/immunology, MESH: Interleukin-15/immunology, Flow Cytometry, Adoptive Transfer, Cell biology, Killer Cells, Natural, Mice, Inbred C57BL, MESH: Adoptive Transfer, Poly I-C, chemistry, Polyinosinic:polycytidylic acid, Interferon Type I, Interleukin 12, [SDV.IMM]Life Sciences [q-bio]/Immunology, Signal Transduction, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f6bb8c37df30c2e732e6299e8ec549Test
https://doi.org/10.4049/jimmunol.1004210Test

المؤلفون: Florian W. R. Vondran, Robert Thimme, Pascal Mutz, Oliver Grünvogel, Katharina Esser-Nobis, Volker Lohmann, Christoph Neumann-Haefelin, Daniel Gotthardt, Ji-Young Lee, Ralf Bartenschlager, Arianeb Mehrabi, Alexander H. Dalpke, Anna Reustle, Ombretta Colasanti, Volker Klöss, Marco Binder, Paul Schnitzler, Sandrine Belouzard, Ronald Koschny, Katrin Hoffmann, Jasper Hesebeck-Brinckmann, Jean Dubuisson

المساهمون: Heidelberg University, Department of Infectious Diseases [Heidelberg, Germany], Heidelberg University Hospital [Heidelberg], Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Universität Heidelberg [Heidelberg] = Heidelberg University, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Hannover Medical School [Hannover] (MHH), German Center for Infection Research [Heidelberg, Germany] (DZIF), University Hospital Freiburg, Albert-Ludwigs-Universität Freiburg, This project was supported by grants from the Deutsche Forschungsgemeinschaft (TRR179-TP17, FOR1202-TP3 to Volker Lohmann, TRR179-TP9, FOR1202-TP1 to Ralf Bartenschlager, TRR179-TP1 to Robert Thimme, and TRR179-TP2 to Christoph Neumann-Haefelin). This work was supported by a grant from the Excellence Cluster Cellular Networks of University of Heidelberg (to Alexander H. Dalpke and Volker Lohmann)., The authors thank Rahel Klein, Ulrike Herian, Uta Haselmann, and Jutta Mohr for excellent technical assistance and Vibor Laketa for microscopy support. We are grateful to the Electron Microscopy Core Facility of the University of Heidelberg for providing access to their equipment and thanks to Dr Charlotta Funaya and Dr Stefan Hillmer for technical support in electron microscopy work. A plasmid encoding TLR3 was a kind gift from T. Espevik, NTNU, Trondheim, Norway. In addition, we thank Daniel Lamarre for helpful discussions., Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Universität Heidelberg [Heidelberg]

المصدر: Gastroenterology
Gastroenterology, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩
Gastroenterology, WB Saunders, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩

مصطلحات موضوعية: MESH: RNA, Double-Stranded/isolation & purification, 0301 basic medicine, MESH: Immunity, Innate, MESH: Interferons/immunology, MESH: Toll-Like Receptor 3/metabolism, viruses, Hepacivirus, MESH: Hepatitis C, Chronic/virology, Virus Replication, Exosomes, medicine.disease_cause, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Interferon, MESH: RNA, Double-Stranded/immunology, Toll-like receptor, MESH: Hepatocytes/metabolism, RIG-I, Gastroenterology, MDA5, 3. Good health, Cell biology, MESH: Interferons/metabolism, MESH: Host-Pathogen Interactions/immunology, Host-Pathogen Interactions, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, RNA, Viral, MESH: Extracellular Vesicles/metabolism, Signal Transduction, medicine.drug, MESH: Toll-Like Receptor 3/immunology, MESH: Hepatitis C, Chronic/blood, Hepatitis C virus, Primary Cell Culture, Biology, MESH: Virus Replication/immunology, Virus, Cell Line, MESH: Primary Cell Culture, Extracellular Vesicles, 03 medical and health sciences, MESH: RNA, Viral/isolation & purification, Virology, medicine, Humans, MESH: RNA, Viral/immunology, MESH: Extracellular Vesicles/immunology, RNA, Double-Stranded, MESH: Hepatitis C, Chronic/immunology, MESH: Humans, Hepatology, MESH: Hepatocytes/immunology, MESH: RNA, Viral/metabolism, MESH: Signal Transduction/immunology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Hepatitis C, Chronic, Immunity, Innate, Toll-Like Receptor 3, MESH: Cell Line, Escape, 030104 developmental biology, MESH: Hepacivirus/physiology, Viral replication, TLR3, Hepatocytes, Interferons, Rab27a, MESH: RNA, Double-Stranded/metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdb70da0420c330868ac469be32c258Test
https://doi.org/10.1053/j.gastro.2018.03.020Test