المؤلفون: Wallace, Michael, J, Malhotra, Nipun, Mariángelo, Juan Ignacio Elio, Stevens, Tyler, L, Young, Lindsay, J, Antwi-Boasiako, Steve, Abdallah, Danielle, Takenaka, Sarah Sumie, Cavus, Omer, Murphy, Nathaniel, P, Han, Mei, Xu, Xianyao, Mangoni, Matteo E., Hund, Thomas, J, Roberts, Jason, D, Györke, Sandor, Mohler, Peter, J, El Refaey, Mona

المساهمون: The Ohio State University Press, Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), McMaster University Hamilton, Ontario, Fondation Leducq TNE FANTASY 19CV03

المصدر: ISSN: 0021-9258.

مصطلحات موضوعية: ankyrin-b, arrhythmia, bradycardia, cardiovascular disease, fibrosis, heart failure, heart rate variability, incomplete penetrance, stress, variant, MESH: Animals, MESH: Humans, MESH: Phenotype, MESH: Aging, MESH: Mice, MESH: Adrenergic Agents, MESH: Ankyrins, MESH: Disease Models, Animal, MESH: Ion Channels, Knockout, MESH: Myocytes, Cardiac, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37182735; hal-04271860; https://hal.science/hal-04271860Test; https://hal.science/hal-04271860/documentTest; https://hal.science/hal-04271860/file/JBC-D-22-02908_accepted.pdfTest; PUBMED: 37182735; PUBMEDCENTRAL: PMC10318515

الإتاحة: https://doi.org/10.1016/j.jbc.2023.104818Test
https://hal.science/hal-04271860Test
https://hal.science/hal-04271860/documentTest
https://hal.science/hal-04271860/file/JBC-D-22-02908_accepted.pdfTest

المؤلفون: Gielen, Marc, Barilone, Nathalie, Corringer, Pierre-Jean

المساهمون: Récepteurs Canaux - Channel Receptors, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU), Financial support by the Fondation de la Recherche Médicale (grant “Équipe FRM” DEQ20140329497 to P.-J.C.) and the European Commission Research Executive Agency (Marie Sklodowska-Curie Action, Individual Fellowship 659371 to M.G., ERC Advanced Grant GA788974 Dynacotine to P.-J.C.). M.G. is grateful to the Fondation Bettencourt Schueller for their support., European Project: 659371,H2020,H2020-MSCA-IF-2014,nAChR PAM-to-gate(2015), European Project: 788974,H2020

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: MESH: Animals, MESH: Computer Simulation, MESH: Protein Conformation, MESH: Protein Subunits, MESH: Receptors, GABA-A, MESH: Synaptic Transmission, MESH: Xenopus laevis, MESH: Ion Channels, MESH: Ion Transport, MESH: Kinetics, MESH: Models, Molecular, MESH: Molecular Conformation, MESH: Mutation, MESH: Nervous System, MESH: Oocytes, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33097732; info:eu-repo/grantAgreement//659371/EU/Gating mechanism and pharmacological modulation of nicotinic acetylcholine receptors/nAChR PAM-to-gate; info:eu-repo/grantAgreement//788974/EU/Signal transduction and allosteric modulation of nicotinic acetylcholine receptors:from ion channel electrophysiology to atomic 3D structures/Dynacotine; pasteur-03088067; https://pasteur.hal.science/pasteur-03088067Test; https://pasteur.hal.science/pasteur-03088067/documentTest; https://pasteur.hal.science/pasteur-03088067/file/Gielen.%202020.pdfTest; PUBMED: 33097732; PUBMEDCENTRAL: PMC7585415

الإتاحة: https://doi.org/10.1038/s41467-020-19218-6Test
https://pasteur.hal.science/pasteur-03088067Test
https://pasteur.hal.science/pasteur-03088067/documentTest
https://pasteur.hal.science/pasteur-03088067/file/Gielen.%202020.pdfTest

المؤلفون: Michalski, Nicolas, Petit, Christine

المساهمون: Génétique et Physiologie de l'Audition, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Institut de la Vision, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Collège de France - Chaire Génétique et physiologie cellulaire, Collège de France (CdF (institution)), This work was supported by the Prix Emergence of the Agir Pour l'Audition foundation to N.M. and by grants from the French Agence Nationale pour la Recherche (ANR), as part of the second Investissements d'Avenir program (ANR-15-RHUS-0001), the LabEx Lifesenses (ANR-10-LABX-65), the European Research Council (ERC-2011-ADG_294570), the BNP Paribas Foundation, the FAUN Stiftung, and the LHW-Stiftung to C.P., ANR-15-RHUS-0001,LIGHT4DEAF,ECLAIRER LA SURDITÉ : UNE APPROCHE HOLISTIQUE DU SYNDROME D'USHER(2015), ANR-10-LABX-0065,LIFESENSES,DES SENS POUR TOUTE LA VIE(2010), European Project: 294570,EC:FP7:ERC,ERC-2011-ADG_20110310,HAIRBUNDLE(2012)

المصدر: ISSN: 0147-006X.

مصطلحات موضوعية: gene regulatory networks, evolution, hair cell, cochlea, auditory hindbrain, auditory cortex, MESH: Animals, MESH: Auditory Pathways, MESH: Genes, MESH: Hair Cells, Auditory, MESH: Hearing Disorders, MESH: Humans, MESH: Ion Channels, MESH: Nerve Tissue Proteins, MESH: Neurogenesis, MESH: Rhombencephalon, MESH: Sensory Receptor Cells, MESH: Transcription Factors, MESH: Biological Evolution, MESH: Cochlea, MESH: Gene Expression Regulation, Developmental, MESH: Gene Ontology, [SDV]Life Sciences [q-bio], [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30699050; info:eu-repo/grantAgreement/EC/FP7/294570/EU/Assembling the puzzle of the operating auditory hair bundle/HAIRBUNDLE; pasteur-02874563; https://pasteur.hal.science/pasteur-02874563Test; https://pasteur.hal.science/pasteur-02874563/documentTest; https://pasteur.hal.science/pasteur-02874563/file/MichalskiPetit_Maintext_31August2018.pdfTest; PUBMED: 30699050

الإتاحة: https://doi.org/10.1146/annurev-neuro-070918-050428Test
https://pasteur.hal.science/pasteur-02874563Test
https://pasteur.hal.science/pasteur-02874563/documentTest
https://pasteur.hal.science/pasteur-02874563/file/MichalskiPetit_Maintext_31August2018.pdfTest

المؤلفون: Benz, Roland, Popoff, Michel, R.

المساهمون: Department of Life Sciences and Chemistry Bremen, Jacobs University = Constructor University Bremen, Toxines bactériennes - Bacterial Toxins, Institut Pasteur Paris (IP), The authors would like to thank Eva Waltenberger and Serge Pauillac for expert technical assistance.

المصدر: EISSN: 2072-6651 ; Toxins ; https://pasteur.hal.science/pasteur-02448636Test ; Toxins, 2018, 10 (9), pp.341. ⟨10.3390/toxins10090341⟩

مصطلحات موضوعية: channel formation, clostridium perfringens enterotoxin (CPE), MTT-test, cation-selectivity, lipid bilayer membrane, pore-forming toxins, propidium iodide uptake, MESH: Animals, MESH: Chlorocebus aethiops, MESH: Clostridium perfringens, MESH: Enterotoxins/toxicity, MESH: Ion Channels/metabolism, MESH: Lipid Bilayers/metabolism, MESH: Propidium/metabolism, MESH: Vero Cells, [SDV]Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30135397; pasteur-02448636; https://pasteur.hal.science/pasteur-02448636Test; https://pasteur.hal.science/pasteur-02448636/documentTest; https://pasteur.hal.science/pasteur-02448636/file/clostridium_perfringens_enterotoxin.pdfTest; PUBMED: 30135397; PUBMEDCENTRAL: PMC6162509

الإتاحة: https://doi.org/10.3390/toxins10090341Test
https://pasteur.hal.science/pasteur-02448636Test
https://pasteur.hal.science/pasteur-02448636/documentTest
https://pasteur.hal.science/pasteur-02448636/file/clostridium_perfringens_enterotoxin.pdfTest

المؤلفون: Cornevaux, Jérémy

المساهمون: Thèses d'exercice et mémoires - UFR des sciences pharmaceutiques et biologiques de Montpellier, Université de Montpellier (UM), Éric Baccino

المصدر: https://dumas.ccsd.cnrs.fr/dumas-04013298Test ; Sciences pharmaceutiques. 2022.

مصطلحات موضوعية: Sudden cardiac death, Iatrogeny, Antipsychotics, Early repolarization, Iatrogénie, Antipsychotiques, Repolarisation précoce, MESH: Mort subite cardiaque, MESH: Syndrome du QT long, MESH: Canaux ioniques, MESH: Torsades de pointes, MESH: Long qt syndrome, MESH: Ion channels, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences

العلاقة: dumas-04013298; https://dumas.ccsd.cnrs.fr/dumas-04013298Test; https://dumas.ccsd.cnrs.fr/dumas-04013298/documentTest; https://dumas.ccsd.cnrs.fr/dumas-04013298/file/2022_CORNEVAUX%20J%C3%A9r%C3%A9my.pdfTest

الإتاحة: https://dumas.ccsd.cnrs.fr/dumas-04013298Test
https://dumas.ccsd.cnrs.fr/dumas-04013298/documentTest
https://dumas.ccsd.cnrs.fr/dumas-04013298/file/2022_CORNEVAUX%20J%C3%A9r%C3%A9my.pdfTest

المؤلفون: Filser, Mathilde, Giansily-Blaizot, Muriel, Grenier, Mélanie, Monedero Alonso, David, Bouyer, Guillaume, Pérès, Laurent, Egée, Stéphane, Aral, Bernard, Airaud, Fabrice, da Costa, Lydie, Picard, Véronique, Cougoul, Pierre, Palach, Marlène, Béziau, Stéphane, Garrec, Céline, Aguilar-Martinez, Patricia, Gardie, Betty, Girodon, François

المساهمون: Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Hôpital Saint Eloi (CHRU Montpellier), Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier), Centre National de la Recherche Scientifique (CNRS), Laboratoire de Biologie Intégrative des Modèles Marins (LBI2M), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff = Roscoff Marine Station (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Excellence : Biogenèse et pathologies du globule rouge (Labex Gr-Ex), Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), AP-HP Hôpital universitaire Robert-Debré Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Henri Mondor d'Aurillac, Nantes Université (Nantes Univ), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL), Lipides - Nutrition - Cancer Dijon - U1231 (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, ANR-11-LABX-0051,GR-Ex,Biogenèse et pathologies du globule rouge(2011)

المصدر: ISSN: 0006-4971.

مصطلحات موضوعية: MESH: Adult, MESH: Cohort Studies, MESH: Female, MESH: Germ-Line Mutation, MESH: Humans, MESH: Ion Channels, MESH: Male, MESH: Middle Aged, MESH: Polycythemia, MESH: Young Adult, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33181827; hal-03654406; https://hal.science/hal-03654406Test; PUBMED: 33181827

الإتاحة: https://doi.org/10.1182/blood.2020008424Test
https://hal.science/hal-03654406Test

المؤلفون: Marc Gielen, Nathalie Barilone, Pierre-Jean Corringer

المساهمون: Récepteurs Canaux - Channel Receptors, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Sorbonne Université (SU), Financial support by the Fondation de la Recherche Médicale (grant 'Équipe FRM' DEQ20140329497 to P.-J.C.) and the European Commission Research Executive Agency (Marie Sklodowska-Curie Action, Individual Fellowship 659371 to M.G., ERC Advanced Grant GA788974 Dynacotine to P.-J.C.). M.G. is grateful to the Fondation Bettencourt Schueller for their support., European Project: 659371,H2020,H2020-MSCA-IF-2014,nAChR PAM-to-gate(2015), European Project: 788974,H2020 | ERC | ERC-ADG,Dynacotine(2019), Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris]

المصدر: Nature Communications
Nature Communications, 2020, 11 (1), pp.5369. ⟨10.1038/s41467-020-19218-6⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5369. ⟨10.1038/s41467-020-19218-6⟩

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein Conformation, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Molecular Conformation, General Physics and Astronomy, Ion channels in the nervous system, Nervous System, Synaptic Transmission, Ion Channels, Xenopus laevis, 0302 clinical medicine, MESH: Protein Conformation, MESH: Animals, Receptor, lcsh:Science, MESH: Receptors, GABA-A, Desensitization (medicine), Multidisciplinary, Ligand-gated ion channels, MESH: Kinetics, Chemistry, GABAA receptor, MESH: Protein Subunits, Cell biology, Ligand-gated ion channel, MESH: Models, Molecular, MESH: Mutation, Protein subunit, Science, Neurophysiology, Neurotransmission, Inhibitory postsynaptic potential, General Biochemistry, Genetics and Molecular Biology, Article, MESH: Oocytes, 03 medical and health sciences, MESH: Computer Simulation, MESH: Xenopus laevis, medicine, MESH: Synaptic Transmission, Animals, Computer Simulation, Ion channel, MESH: Molecular Conformation, Ion Transport, MESH: Nervous System, General Chemistry, Receptors, GABA-A, MESH: Ion Transport, Kinetics, Protein Subunits, 030104 developmental biology, nervous system, Mutation, MESH: Ion Channels, Oocytes, lcsh:Q, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fac1e1410b215634dec897333789ceeTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-03088067Test

المؤلفون: Farfariello, Valerio, Prevarskaya, Natalia, Gkika, Dimitra

المساهمون: Laboratoire de Physiologie Cellulaire : Canaux ioniques, inflammation et cancer - U 1003 (PHYCELL), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Rôle des canaux ioniques membranaires et du calcium intracellulaire dans la psysiopathologie de la prostate, Institut National de la Santé et de la Recherche Médicale (INSERM), Rôle des canaux ioniques membranaires et du calcium intracellulaire dans la physiopathologie de la prostate, Université de Lille, Sciences et Technologies-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: ISSN: 0303-4240.

مصطلحات موضوعية: Calcium, Cancer biomarkers, Chloride, Ion channels, Neuroendocrine cells, Potassium, Stroma cells, Transient receptor potential, Tumor-derived endothelial cells, MESH: Carcinogenesis, MESH: Early Detection of Cancer, MESH: Humans, MESH: Ion Channels, MESH: Male, MESH: Prostatic Neoplasms, MESH: Tumor Microenvironment, [SDV.CAN]Life Sciences [q-bio]/Cancer

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32737754; hal-04277347; https://hal.science/hal-04277347Test; PUBMED: 32737754

الإتاحة: https://doi.org/10.1007/112_2020_22Test
https://hal.science/hal-04277347Test

المؤلفون: Spurny, Radovan, Ramerstorfer, Joachim, Price, Kerry, Brams, Marijke, Ernst, Margot, Nury, Hugues, Verheij, Mark, Legrand, Pierre, Bertrand, Daniel, Bertrand, Sonia, Dougherty, Dennis, de Esch, Iwan, Corringer, Pierre-Jean, Sieghart, Werner, Lummis, Sarah, Ulens, Chris

المساهمون: Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), Medizinische Universität Wien = Medical University of Vienna, University of Cambridge UK (CAM), Récepteurs-Canaux, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Vrije Universiteit Amsterdam Amsterdam (VU), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), California Institute of Technology (CALTECH), Grant KULeuven OT/08/048, Wellcome Trut, Austrian Science Fund Grant P19653, National Institutes of Health Grant NS 34407

المصدر: ISSN: 0027-8424.

مصطلحات موضوعية: MESH: Animals, MESH: Benzodiazepines, MESH: Ion Channels, MESH: Ligands, MESH: Models, Molecular, MESH: Receptors, GABA-A, MESH: Xenopus, MESH: gamma-Aminobutyric Acid, MESH: Binding Sites, MESH: Biopolymers, MESH: Crystallography, X-Ray, MESH: Ion Channel Gating, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/23035248; pasteur-01721946; https://pasteur.hal.science/pasteur-01721946Test; https://pasteur.hal.science/pasteur-01721946/documentTest; https://pasteur.hal.science/pasteur-01721946/file/E3028.full.pdfTest; PUBMED: 23035248

الإتاحة: https://doi.org/10.1073/pnas.1208208109Test
https://pasteur.hal.science/pasteur-01721946Test
https://pasteur.hal.science/pasteur-01721946/documentTest
https://pasteur.hal.science/pasteur-01721946/file/E3028.full.pdfTest

المؤلفون: Corringer, Pierre-Jean, Baaden, Marc, Bocquet, Nicolas, Delarue, Marc, Dufresne, Virginie, Nury, Hugues, Prevost, Marie, van Renterghem, Catherine

المساهمون: Récepteurs-Canaux, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de biochimie théorique Paris (LBT (UPR_9080)), Institut de biologie physico-chimique (IBPC (FR_550)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Dynamique Structurale des Macromolécules (DSM), This work was supported by the Commission of the European Communities (Neurocypres project), the Louis D. fundation from the Institut de France and the Network of European Neuroscience Institutes (ENI‐NET)., European Project: 202088,EC:FP7:HEALTH,FP7-HEALTH-2007-A,NEUROCYPRES(2008), European Project: 32730,ENINET

المصدر: ISSN: 0022-3751.

مصطلحات موضوعية: MESH: Amino Acid Sequence, MESH: Bacterial Proteins, MESH: Crystallography, X-Ray, MESH: Ion Channel Gating, MESH: Ion Channels, MESH: Molecular Sequence Data, MESH: Protein Structure, Quaternary, Tertiary, MESH: Receptors, Neurotransmitter, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/19995852; info:eu-repo/grantAgreement/EC/FP7/202088/EU/Neurotransmitter Cys-loop receptors: structure, function and disease/NEUROCYPRES; info:eu-repo/grantAgreement//32730/EU/Network of European Neuroscience Institutes/ENINET; pasteur-02174745; https://pasteur.hal.science/pasteur-02174745Test; https://pasteur.hal.science/pasteur-02174745/documentTest; https://pasteur.hal.science/pasteur-02174745/file/Corringer_et_al-2010-The_Journal_of_Physiology.pdfTest; PUBMED: 19995852; PUBMEDCENTRAL: PMC2828131

الإتاحة: https://doi.org/10.1113/jphysiol.2009.183160Test
https://pasteur.hal.science/pasteur-02174745Test
https://pasteur.hal.science/pasteur-02174745/documentTest
https://pasteur.hal.science/pasteur-02174745/file/Corringer_et_al-2010-The_Journal_of_Physiology.pdfTest