يعرض 1 - 6 نتائج من 6 نتيجة بحث عن '"MESH: Hepatitis C, Chronic/blood"', وقت الاستعلام: 1.34s تنقيح النتائج
  1. 1

    المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département d'hépatologie, Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Epidémiologie, systèmes d'information, modélisation, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Departement d'Hépatho-Gastro-Enterologie [Mondor], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre Hospitalier Universitaire Henri Mondor, Centre d'Immunologie Humaine (CIH), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Service de santé publique [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Immunité et Infection, Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR113-Institut National de la Santé et de la Recherche Médicale (INSERM), Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratory of Human Genetics of Infectious Diseases, Rockefeller University [New York]-Rockefeller Branch, Biomarqueurs CArdioNeuroVASCulaires (BioCANVAS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Department of anesthesiology and critical care medicine, Hôpitaux Universitaire Saint-Louis, Lariboisière, Fernand-Widal, Département Infection et Epidémiologie - Department of Infection and Epidemiology, Institut Pasteur [Paris], The CUPIC Cohort study was sponsored and funded by The National Agency for research on Aids and Viral Hepatitis (ANRS), with support by the French Association for the Study of the Liver(AFEF). The authors also wish to acknowledge the Center for Human Immunology for its support of the research project., Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut Pasteur [Paris] (IP), CHU Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Centre Hospitalier Universitaire Henri Mondor, Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Saint-Antoine [APHP], Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR113-Université Pierre et Marie Curie - Paris 6 (UPMC), Rockefeller Branch-rockefeller university, Institut Cochin ( UM3 (UMR 8104 / U1016) ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Assistance publique - Hôpitaux de Paris (AP-HP)-Centre Hospitalier Universitaire Henri Mondor, Centre d'Immunologie Humaine ( CIH ), Centre Hospitalier Régional Universitaire de Nancy ( CHRU Nancy ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Saint-Antoine [APHP], Institut National de la Santé et de la Recherche Médicale ( INSERM ) -IFR113-Université Pierre et Marie Curie - Paris 6 ( UPMC ), Imagine - Institut des maladies génétiques ( IMAGINE - U1163 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Paris Descartes - Paris 5 ( UPD5 ), Biomarqueurs CArdioNeuroVASCulaires ( BioCANVAS ), Université Paris Diderot - Paris 7 ( UPD7 ) -Université Paris 13 ( UP13 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Département Infection et Epidémiologie

    المصدر: Liver International
    Liver International, Wiley-Blackwell, 2015, 35 (7), pp.1833-1844. ⟨10.1111/liv.12759⟩
    Liver International, 2015, 35 (7), pp.1833-1844. ⟨10.1111/liv.12759⟩
    Liver International, Wiley-Blackwell, 2015, 35 (7), pp.1833-1844. 〈10.1111/liv.12759〉

    مصطلحات موضوعية: Male, MESH : Aged, MESH : Prospective Studies, MESH : Viral Load, MESH : Hepatitis C, Chronic/blood, Hepacivirus, MESH : Virus Replication/drug effects, Polyethylene Glycols, MESH: Molecular Targeted Therapy, [ SDV.IMM ] Life Sciences [q-bio]/Immunology, Molecular Targeted Therapy, Prospective Studies, MESH: Ribavirin/therapeutic use, MESH : Proline/analogs & derivatives, MESH: Treatment Outcome, MESH : Hepacivirus/drug effects, MESH: Viral Nonstructural Proteins/metabolism, MESH: Middle Aged, MESH: RNA, Viral/blood, virus diseases, MESH : beta 2-Glycoprotein I/blood, Blood proteins, 3. Good health, beta 2-Glycoprotein I, Area Under Curve, MESH: Hepacivirus/genetics, Drug Therapy, Combination, Oligopeptides, Apolipoprotein H, MESH : Biomarkers/blood, MESH: Hepatitis C, Chronic/drug therapy, Proline, MESH: Hepatitis C, Chronic/blood, virological response, MESH: Proline/analogs & derivatives, MESH : Antiviral Agents/therapeutic use, Antiviral Agents, MESH : Proline/therapeutic use, Boceprevir, MESH : Recombinant Proteins/therapeutic use, Humans, chronic hepatitis C, MESH : Middle Aged, Protease Inhibitors, MESH: Interferon-alpha/therapeutic use, MESH : Predictive Value of Tests, Aged, MESH: Polyethylene Glycols/therapeutic use, MESH : Hepacivirus/genetics, MESH: Humans, Surrogate endpoint, MESH : Humans, MESH: beta 2-Glycoprotein I/blood, MESH: ROC Curve, digestive system diseases, chemistry, MESH: Protease Inhibitors/therapeutic use, Immunology, MESH: Female, Biomarkers, Time Factors, MESH : Viral Nonstructural Proteins/antagonists & inhibitors, MESH : Hepatitis C, Chronic/diagnosis, MESH : Protease Inhibitors/therapeutic use, Viral Nonstructural Proteins, Virus Replication, MESH : Polyethylene Glycols/therapeutic use, HCV protease inhibitor, Telaprevir, MESH: Virus Replication/drug effects, MESH: Proline/therapeutic use, chemistry.chemical_compound, apolipoprotein H, MESH: Hepacivirus/drug effects, MESH : RNA, Viral/blood, MESH : Female, MESH: Hepatitis C, Chronic/diagnosis, MESH : Viral Nonstructural Proteins/metabolism, MESH: Aged, Middle Aged, Viral Load, MESH: Hepacivirus/growth & development, Recombinant Proteins, MESH: Predictive Value of Tests, MESH : Hepacivirus/enzymology, Treatment Outcome, RNA, Viral, biomarker, [SDV.IMM]Life Sciences [q-bio]/Immunology, Biomarker (medicine), Female, France, MESH: Viral Load, MESH : Oligopeptides/therapeutic use, MESH : Time Factors, medicine.drug, MESH : Hepatitis C, Chronic/drug therapy, MESH : Molecular Targeted Therapy, MESH: Biomarkers/blood, MESH: Hepacivirus/enzymology, MESH : Male, MESH : Ribavirin/therapeutic use, MESH : Interferon-alpha/therapeutic use, MESH : Treatment Outcome, Biology, Predictive Value of Tests, MESH: Recombinant Proteins/therapeutic use, Ribavirin, medicine, MESH : France, NS3, MESH: Viral Nonstructural Proteins/antagonists & inhibitors, Hepatology, MESH : Drug Therapy, Combination, MESH: Time Factors, Interferon-alpha, Hepatitis C, Chronic, MESH : Hepacivirus/growth & development, MESH: Male, MESH: Prospective Studies, MESH: France, MESH: Drug Therapy, Combination, ROC Curve, MESH: Antiviral Agents/therapeutic use, MESH: Oligopeptides/therapeutic use, MESH: Area Under Curve, MESH : Area Under Curve, MESH : ROC Curve

  2. 2

    المساهمون: Heidelberg University, Department of Infectious Diseases [Heidelberg, Germany], Heidelberg University Hospital [Heidelberg], Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Universität Heidelberg [Heidelberg] = Heidelberg University, German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ), Hannover Medical School [Hannover] (MHH), German Center for Infection Research [Heidelberg, Germany] (DZIF), University Hospital Freiburg, Albert-Ludwigs-Universität Freiburg, This project was supported by grants from the Deutsche Forschungsgemeinschaft (TRR179-TP17, FOR1202-TP3 to Volker Lohmann, TRR179-TP9, FOR1202-TP1 to Ralf Bartenschlager, TRR179-TP1 to Robert Thimme, and TRR179-TP2 to Christoph Neumann-Haefelin). This work was supported by a grant from the Excellence Cluster Cellular Networks of University of Heidelberg (to Alexander H. Dalpke and Volker Lohmann)., The authors thank Rahel Klein, Ulrike Herian, Uta Haselmann, and Jutta Mohr for excellent technical assistance and Vibor Laketa for microscopy support. We are grateful to the Electron Microscopy Core Facility of the University of Heidelberg for providing access to their equipment and thanks to Dr Charlotta Funaya and Dr Stefan Hillmer for technical support in electron microscopy work. A plasmid encoding TLR3 was a kind gift from T. Espevik, NTNU, Trondheim, Norway. In addition, we thank Daniel Lamarre for helpful discussions., Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Universität Heidelberg [Heidelberg]

    المصدر: Gastroenterology
    Gastroenterology, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩
    Gastroenterology, WB Saunders, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩

    مصطلحات موضوعية: MESH: RNA, Double-Stranded/isolation & purification, 0301 basic medicine, MESH: Immunity, Innate, MESH: Interferons/immunology, MESH: Toll-Like Receptor 3/metabolism, viruses, Hepacivirus, MESH: Hepatitis C, Chronic/virology, Virus Replication, Exosomes, medicine.disease_cause, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Interferon, MESH: RNA, Double-Stranded/immunology, Toll-like receptor, MESH: Hepatocytes/metabolism, RIG-I, Gastroenterology, MDA5, 3. Good health, Cell biology, MESH: Interferons/metabolism, MESH: Host-Pathogen Interactions/immunology, Host-Pathogen Interactions, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, RNA, Viral, MESH: Extracellular Vesicles/metabolism, Signal Transduction, medicine.drug, MESH: Toll-Like Receptor 3/immunology, MESH: Hepatitis C, Chronic/blood, Hepatitis C virus, Primary Cell Culture, Biology, MESH: Virus Replication/immunology, Virus, Cell Line, MESH: Primary Cell Culture, Extracellular Vesicles, 03 medical and health sciences, MESH: RNA, Viral/isolation & purification, Virology, medicine, Humans, MESH: RNA, Viral/immunology, MESH: Extracellular Vesicles/immunology, RNA, Double-Stranded, MESH: Hepatitis C, Chronic/immunology, MESH: Humans, Hepatology, MESH: Hepatocytes/immunology, MESH: RNA, Viral/metabolism, MESH: Signal Transduction/immunology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Hepatitis C, Chronic, Immunity, Innate, Toll-Like Receptor 3, MESH: Cell Line, Escape, 030104 developmental biology, MESH: Hepacivirus/physiology, Viral replication, TLR3, Hepatocytes, Interferons, Rab27a, MESH: RNA, Double-Stranded/metabolism

  3. 3

    المساهمون: National Institute of Allergy and Infectious Diseases [Bethesda] (NIAID-NIH), National Institutes of Health [Bethesda] (NIH), Critical Care Medicine Department, National Institutes of Health - NIH, Division of Infectious Diseases, Department of Microbiology and Immunology, Medical University of South Carolina [Charleston] (MUSC), Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institute of Human Virology (IHV), University of Maryland [Baltimore County] (UMBC), University of Maryland System-University of Maryland System, Centre d'Immunologie Humaine (CIH), This project was supported by federal funds from the intramural program of the National Institute of Allergy and Infectious Diseases, a PasteurInnov grant (Institut Pasteur), and the European Union FP7 grant PoC-HCV (GA n° 601851). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript., European Project: 601851,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-2,POC-HCV(2013), Vougny, Marie-Christine, Point-of-care tests to revolutionise the clinical management of patients infected by Hepatitis C virus - POC-HCV - - EC:FP7:HEALTH2013-09-01 - 2016-08-31 - 601851 - VALID, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)

    المصدر: PLoS ONE
    PLoS ONE, 2015, 10 (7), pp.e0133236. ⟨10.1371/journal.pone.0133236⟩
    PLoS ONE, Vol 10, Iss 7, p e0133236 (2015)
    PLoS ONE, Public Library of Science, 2015, 10 (7), pp.e0133236. ⟨10.1371/journal.pone.0133236⟩

    مصطلحات موضوعية: Male, MESH: Hepacivirus/drug effects, Sofosbuvir, MESH: Fluorenes/therapeutic use, Hepacivirus, lcsh:Medicine, MESH: Hepatitis C, Chronic/virology, Blood plasma, medicine.disease_cause, Virus Replication, chemistry.chemical_compound, Recurrence, Viral replication, MESH: Interferons, Enzyme-linked immunoassays, MESH: Ribavirin/therapeutic use, lcsh:Science, MESH: Dipeptidyl Peptidase 4/blood, media_common, MESH: Treatment Outcome, Multidisciplinary, biology, Hepatitis C virus, Convalescence, virus diseases, MESH: Protein Processing, Post-Translational, Viral Load, MESH: Virus Replication/drug effects, 3. Good health, Treatment Outcome, MESH: Dipeptidyl Peptidase 4/genetics, [SDV.IMM]Life Sciences [q-bio]/Immunology, Drug Therapy, Combination, Female, Chemokines, Viral load, medicine.drug, Research Article, Ledipasvir, Adult, MESH: Sofosbuvir/therapeutic use, MESH: Hepatitis C, Chronic/drug therapy, [SDV.IMM] Life Sciences [q-bio]/Immunology, media_common.quotation_subject, Dipeptidyl Peptidase 4, MESH: Chemokine CXCL10/genetics, MESH: Convalescence, Antiviral Agents, MESH: Benzimidazoles/therapeutic use, MESH: Viral Load/drug effects, Ribavirin, MESH: Hepacivirus/physiology, medicine, Humans, Fluorenes, MESH: Humans, business.industry, lcsh:R, Correction, MESH: Adult, Hepatitis C, Chronic, MESH: Chemokine CXCL10/blood, biology.organism_classification, Statistical data, digestive system diseases, MESH: Male, Post translational modifications, MESH: Recurrence, Chemokine CXCL10, Regimen, MESH: Drug Therapy, Combination, chemistry, MESH: Hepatitis C, Chronic/blood, Immunology, MESH: Antiviral Agents/therapeutic use, lcsh:Q, Benzimidazoles, Interferons, business, Protein Processing, Post-Translational, MESH: Female, Biomarkers, MESH: Hepatitis C, Chronic/genetics

    وصف الملف: application/force-download

  4. 4

    المساهمون: Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Myriad rules based medicine, CHU Rouen, Normandie Université (NU), Service d'hépatologie médicale [CHU Cochin], Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre d'Immunologie Humaine (CIH), The work was funded by grants obtained from L'Institut National du Cancer (INCA), the European Research Council (ERC) and a private donation from Caisse de Retraite et de Prévoyance des Clercs et Employés de Notaires (CRPCEN)., The authors would like to thank members of the Centre d'Immunology Humaine (CIH) and the Pôle Integré de Recherche Clinique (PIRC) Institut Pasteur, and the members of the Liver Unit, Hopital Cochin for support of this work., Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Cochin [AP-HP], Centre d'Immunologie Humaine ( CIH )

    المصدر: Clinical and Experimental Immunology
    Clinical and Experimental Immunology, Wiley, 2012, 167 (1), pp.137-148. ⟨10.1111/j.1365-2249.2011.04488.x⟩
    Clinical and Experimental Immunology, 2012, 167 (1), pp.137-148. ⟨10.1111/j.1365-2249.2011.04488.x⟩
    Clinical and Experimental Immunology, Wiley, 2012, 167 (1), pp.137-148. 〈10.1111/j.1365-2249.2011.04488.x〉

    مصطلحات موضوعية: Male, MESH: Inflammation, MESH: Carcinoma, Transitional Cell/urine, MESH : Aged, MESH : Hepatitis C, Chronic/blood, Immunoenzyme Techniques, MESH: Protein Structure, Tertiary, 0302 clinical medicine, MESH : Culture Media, Conditioned/chemistry, MESH: Chemokine CXCL10/analysis, [ SDV.IMM ] Life Sciences [q-bio]/Immunology, Protein Isoforms, Multiplex, MESH: Protein Isoforms/immunology, MESH: Culture Media, Conditioned/chemistry, Aged, 80 and over, MESH: Recombinant Fusion Proteins/analysis, 0303 health sciences, MESH: Middle Aged, Antibodies, Monoclonal, Atopic dermatitis, MESH: Enzyme-Linked Immunosorbent Assay/methods, MESH : Protein Isoforms/immunology, Neoplasm Proteins, 3. Good health, MESH : Peptide Fragments/immunology, MESH: Urinary Bladder Neoplasms/urine, MESH : Antibodies, Monoclonal/immunology, bladder cancer, MESH : Protein Structure, Tertiary, Agonist, MESH: Chemokine CXCL10/immunology, MESH: Protein Isoforms/analysis, MESH: Hepatitis C, Chronic/blood, Recombinant Fusion Proteins, Immunology, MESH : Body Fluids/chemistry, 03 medical and health sciences, MESH: Peptide Fragments/immunology, MESH : Immunoenzyme Techniques/methods, MESH: Antibodies, Monoclonal/immunology, Humans, MESH : Middle Aged, MESH : Aged, 80 and over, MESH : Protein Processing, Post-Translational, Aged, MESH : Inflammation, MESH: Humans, MESH : Humans, MESH: Adult, MESH: Peptide Fragments/analysis, medicine.disease, Peptide Fragments, Protein Structure, Tertiary, Chemokine CXCL10, Urinary Bladder Neoplasms, chemokines/monokines, Culture Media, Conditioned, MESH: Dipeptidyl Peptidase 4/metabolism, MESH : Recombinant Fusion Proteins/analysis, MESH: Female, Biomarkers, MESH : Protein Isoforms/analysis, hepatitis C virus, MESH : Carcinoma, Transitional Cell/urine, Translational Studies, MESH: Body Fluids/chemistry, medicine.disease_cause, MESH: Neoplasm Proteins/urine, MESH: Aged, 80 and over, Immunology and Allergy, MESH : Female, BCG, MESH : Biomarkers, MESH: Aged, Predictive marker, MESH : Adult, Middle Aged, Body Fluids, MESH : Neoplasm Proteins/urine, MESH : Enzyme-Linked Immunosorbent Assay/methods, MESH : Chemokine CXCL10/immunology, Biomarker (medicine), [SDV.IMM]Life Sciences [q-bio]/Immunology, Female, Adult, medicine.drug_class, MESH : Male, Dipeptidyl Peptidase 4, Hepatitis C virus, Enzyme-Linked Immunosorbent Assay, MESH : Chemokine CXCL10/analysis, MESH : Dipeptidyl Peptidase 4/metabolism, medicine, MESH : Urinary Bladder Neoplasms/urine, MESH : Peptide Fragments/analysis, 030304 developmental biology, Inflammation, Carcinoma, Transitional Cell, business.industry, MESH: Immunoenzyme Techniques/methods, Cancer, Hepatitis C, Chronic, MESH: Male, Transplantation, MESH: Protein Processing, Post-Translational, MESH: Biomarkers, business, Protein Processing, Post-Translational, 030215 immunology

  5. 5

    المساهمون: Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Unité d'Hépatologie, Assistance publique - Hôpitaux de Paris (AP-HP), Institut Cochin ( UM3 (UMR 8104 / U1016) ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Centre d'immunologie humaine ( CIH ), Rules-Based Medicine, Epidémiologie des Maladies Emergentes, Conservatoire National des Arts et Métiers [CNAM] ( CNAM ) -Institut Pasteur [Paris]-Pasteur-Cnam risques infectieux et émergents ( PACRI ), Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] ( CNAM ), This work was supported in part by grants from the Agence Nationale de Recherche sur le Sida et les hépatites virales (ANRS) and the European Research Council (ERC)., Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'immunologie humaine (CIH), Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Pasteur-Cnam risques infectieux et émergents (PACRI)

    المصدر: Journal of Clinical Investigation
    Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (1), pp.308-17. 〈10.1172/JCI40594〉
    Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (1), pp.308-17. ⟨10.1172/JCI40594⟩
    Journal of Clinical Investigation, 2011, 121 (1), pp.308-17. ⟨10.1172/JCI40594⟩

    مصطلحات موضوعية: Chemokine, MESH: Treatment Failure, T-Lymphocytes, MESH : Hepatitis C, Chronic/blood, MESH: Hepatitis C, Chronic/virology, medicine.disease_cause, MESH : Polyethylene Glycols/therapeutic use, MESH: Receptors, CXCR3/blood, Polyethylene Glycols, MESH: Recombinant Proteins, chemistry.chemical_compound, 0302 clinical medicine, [ SDV.IMM ] Life Sciences [q-bio]/Immunology, Treatment Failure, MESH: Ribavirin/therapeutic use, MESH : Hepatitis C, Chronic/therapy, 0303 health sciences, MESH : Prognosis, MESH: Dipeptidyl Peptidase 4/blood, MESH: Protein Array Analysis, virus diseases, General Medicine, MESH : Protein Array Analysis, Prognosis, Recombinant Proteins, 3. Good health, MESH: Peptide Fragments/blood, MESH: Chemokine CXCL10/blood, 030220 oncology & carcinogenesis, [SDV.IMM]Life Sciences [q-bio]/Immunology, MESH: Chemokine CXCL10/antagonists & inhibitors, MESH : Chemokine CXCL10/blood, Proteases, Receptors, CXCR3, MESH: T-Lymphocytes/virology, MESH: Hepatitis C, Chronic/blood, MESH : Recombinant Proteins, Hepatitis C virus, Dipeptidyl Peptidase 4, Protein Array Analysis, MESH : Ribavirin/therapeutic use, MESH : Interferon-alpha/therapeutic use, Biology, Interferon alpha-2, MESH : Antiviral Agents/therapeutic use, Antiviral Agents, MESH : Chemokine CXCL10/antagonists & inhibitors, Dipeptidyl peptidase, MESH: Antiviral Agents/therapeutic use, MESH: Prognosis, MESH : T-Lymphocytes/virology, 03 medical and health sciences, MESH : Treatment Failure, MESH: T-Lymphocytes/immunology, Ribavirin, medicine, CXCL10, Humans, MESH: Interferon-alpha/therapeutic use, MESH : Hepatitis C, Chronic/virology, 030304 developmental biology, MESH: Polyethylene Glycols/therapeutic use, MESH: Humans, MESH : Hepatitis C, Chronic/immunology, MESH: Hepatitis C, Chronic/immunology, MESH : Humans, Antagonist, MESH: Hepatitis C, Chronic/therapy, Interferon-alpha, Hepatitis C, Chronic, Virology, Peptide Fragments, MESH : Dipeptidyl Peptidase 4/blood, MESH : T-Lymphocytes/immunology, MESH : Peptide Fragments/blood, Chemokine CXCL10, Chronic infection, chemistry, Immunology, biology.protein, MESH : Receptors, CXCR3/blood

  6. 6

    المساهمون: Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Université de Lille, Droit et Santé, Supported by the Agence Nationale de Recherche sur le SIDA et les He ́patitesVirales (ANRS) and the ARC. C.V. was supported by fellowships from the ANRSand J.D. is an international scholar of the Howard Hughes Medical Institute., We thank Laurence Cocquerel for helpful comments on the manuscript, Yves Rouillé for help in the experiments concerning non‐HCV viruses, and André Pillez and Sophana Ung for technical assistance. We are grateful to T. Wakita, J. McKeating, J. Ball, B. Bartosch, FL. Cosset, T. Pietschamnn, and R. Bartenschlager for providing us with reagents.

    المصدر: Hepatology
    Hepatology, Wiley-Blackwell, 2006, 44, pp.1626-1634. ⟨10.1002/hep.21406⟩