دورية أكاديمية

Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation

التفاصيل البيبلوغرافية
العنوان: Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation
المؤلفون: Matta, Anthony, G, Lhermusier, Thibault, Parada, Francisco, Campelo, Bouisset, Frederic, Canitrot, Ronan, Nader, Vanessa, Blanco, Stéphanie, Elbaz, Meyer, Roncalli, Jerome, Carrié, Didier
المساهمون: Holy-Spirit University of Kaslik Jounieh, Service Cardiologie CHU Toulouse, Pôle Cardiovasculaire et Métabolique CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Department of Psychiatry, Julius-Maximilians-Universität Würzburg (JMU)
المصدر: ISSN: 0896-4327.
بيانات النشر: HAL CCSD
Wiley-Blackwell
سنة النشر: 2021
المجموعة: Université Toulouse III - Paul Sabatier: HAL-UPS
مصطلحات موضوعية: MESH: Aged, 80 and over, MESH: Percutaneous Coronary Intervention, MESH: Retrospective Studies, MESH: Transcatheter Aortic Valve Replacement, MESH: Aortic Valve Stenosis / surgery, MESH: Coronary Artery Disease / therapy, MESH: Female, MESH: Fibrinolytic Agents / therapeutic use, MESH: Hemorrhage / epidemiology, MESH: Hospital Mortality, MESH: Humans, MESH: Male, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
الوصف: International audience ; Introduction: The prevalence of coronary artery disease (CAD) detected in preoperative work-up for transcatheter aortic valve implantation (TAVI) is high. Instead, the management of a concomitant CAD remains unclear. We evaluate the impact of CAD and percutaneous coronary intervention (PCI) on TAVI procedures.Materials and methods: A retrospective study was conducted on 1336 consecutive patients who underwent TAVI in Toulouse University Hospital, Rangueil, France. The studied population was divided into 2 groups: CAD-TAVI group and No CAD-TAVI group. Then, the CAD-TAVI group was segregated into 2 subgroups: PCI-TAVI group and No PCI-TAVI group. In-hospital adverse clinical outcomes were assessed in each group.Results: Pre-TAVI work-up revealed significant CAD in 36% of 1030 patients eligible for inclusion in the study. The overall prevalence of in-hospital death, stroke, major or life-threatening bleeding, minor bleeding, major vascular complications, minor vascular complications, pacemaker implantation, and acute kidney injury was 2.7%, 2.4%, 2.8%, 3.6%, 3.9%, 7.5%, 12.5%, and 2.7%, respectively. Among the studied population, 55% were admitted to the cardiac care unit. No significant statistical difference was observed between groups. Discussion. CAD-TAVI population was not more likely to develop in-hospital adverse clinical outcomes post-TAVI procedure compared to others. Also, no significant difference regarding in-hospital death was observed. In parallel, performing PCI prior to TAVI did not increase the risk of in-hospital death and complications. The difference in terms of the distribution of antithrombotic regimen may explain the higher prevalence of bleeding events in the PCI-TAVI group.Conclusion: This study provides direct clinical relevance useful in daily practice. No negative impact has been attributed to the presence of a concomitant CAD and/or preoperative PCI on the TAVI hospitalization period.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33824628; hal-04511211; https://ut3-toulouseinp.hal.science/hal-04511211Test; https://ut3-toulouseinp.hal.science/hal-04511211/documentTest; https://ut3-toulouseinp.hal.science/hal-04511211/file/Matta_2021.pdfTest; PUBMED: 33824628; PUBMEDCENTRAL: PMC8016584
DOI: 10.1155/2021/6672400
الإتاحة: https://doi.org/10.1155/2021/6672400Test
https://ut3-toulouseinp.hal.science/hal-04511211Test
https://ut3-toulouseinp.hal.science/hal-04511211/documentTest
https://ut3-toulouseinp.hal.science/hal-04511211/file/Matta_2021.pdfTest
حقوق: info:eu-repo/semantics/OpenAccess
رقم الانضمام: edsbas.4998935E
قاعدة البيانات: BASE