المؤلفون: Karl Persson, Agnès Llored, Matteo De Chiara, Agurtzane Irizar, Simon Stenberg, Gianni Liti, Eric Gilson, Benjamin Barré, Jia-Xing Yue, Joseph Schacherer, Melania D’Angiolo, Jonas Warringer, Roberto Marangoni

المساهمون: Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)

المصدر: Nature
Nature, Nature Publishing Group, 2020, 587 (7834), pp.420-425. ⟨10.1038/s41586-020-2889-1⟩

مصطلحات موضوعية: [SDV]Life Sciences [q-bio], Lineage (evolution), Loss of Heterozygosity, yeast, Paradoxus, Genome, 0302 clinical medicine, MESH: Genetic Fitness, MESH: Genetic Introgression, Homologous Recombination, MESH: Phylogeny, Phylogeny, MESH: Evolution, Molecular, MESH: Reproduction, Asexual, 0303 health sciences, Multidisciplinary, biology, MESH: Genomic Instability, MESH: Genomics, Fungal genetics, Genomics, Reproductive isolation, MESH: Crosses, Genetic, MESH: Saccharomyces cerevisiae, Meiosis, yeast, Alpechin, genomic introgression, MESH: Genome, Fungal, Genome, Fungal, Mitosis, Alpechin, Introgression, Saccharomyces cerevisiae, Genetic Introgression, Genomic Instability, Evolution, Molecular, MESH: Homologous Recombination, Saccharomyces, 03 medical and health sciences, Reproduction, Asexual, Saccharomyces paradoxus, Crosses, Genetic, 030304 developmental biology, MESH: Loss of Heterozygosity, MESH: Saccharomyces, MESH: Fertility, genomic introgression, MESH: Mitosis, biology.organism_classification, MESH: Meiosis, Fertility, Evolutionary biology, Genetic Fitness, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142f99605d1b0b08a07acc27b84f2207Test
https://doi.org/10.1038/s41586-020-2889-1Test

المؤلفون: Agnès Thierry, Varun Khanna, Bernard Dujon

المساهمون: Génétique des génomes - Genetics of Genomes (UMR 3525), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), This research was funded in part by contract DYGEVO from Agence Nationale pour la Recherche (France) under programme blanc 2011 section SVSE6., We thank Laurence Ma, Christiane Bouchier and all members of the genomic platform of Institut Pasteur for genomic sequences and our colleagues from the Unité de Génétique moléculaire des levures for fruitful discussions., ANR-11-BSV6-0001,DYGEVO,Dynamique et évolution des génomes de levures, modèles eucaryotes unicellulaires.(2011)

المصدر: Genes
Volume 12
Issue 11
Genes, 2021, 12 (11), pp.1678. ⟨10.3390/genes12111678⟩
Genes, Vol 12, Iss 1678, p 1678 (2021)

مصطلحات موضوعية: MESH: Repetitive Sequences, Nucleic Acid, Saccharomyces cerevisiae Proteins, Whole Genome Sequencing, palindrome, retrotransposon, Saccharomyces cerevisiae, QH426-470, yeast, amplification, MESH: Chromosomes, Fungal, MESH: Saccharomyces cerevisiae, Article, MESH: Saccharomyces cerevisiae Proteins, MESH: Directed Molecular Evolution, MESH: Genome, Fungal, Genetics, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Chromosomes, Fungal, Directed Molecular Evolution, Genome, Fungal, MESH: Whole Genome Sequencing, genome, Repetitive Sequences, Nucleic Acid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6b5d5d18ee691d620045fdbe844796f9Test

المؤلفون: Gröhs Ferrareze, Patrícia Aline, Maufrais, Corinne, Silva Araujo Streit, Rodrigo, Priest, Shelby, Cuomo, Christina, Heitman, Joseph, Staats, Charley Christian, Janbon, Guilhem

المساهمون: Biologie des ARN des Pathogènes fongiques - RNA Biology of Fungal Pathogens, Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Universidade Federal do Rio Grande do Sul [Porto Alegre] (UFRGS), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Duke University Medical Center, Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], PAGF was supported by a CAPES exchange grant (Advanced Network of Computational Biology—RABICÓ – Grant no. 23038.010041/2013-13). This work was supported by a CAPES COFECUB grant n°39712ZK to GJ, by a CNPq grant (309897/2017-3) to CCS, and by a NIH/NIAID R37 MERIT Award AI39115-23 and a NIH/NIAID R01 Award AI50113-16 to JH. JH is co-director and fellow of CIFAR program Fungal Kingdom: Threats & Opportunities. SJP was supported by the NIH/NIAID F31 Fellowship 1F31AI143136-02., Members of the Heitman laboratory are acknowledged for valuable discussion.

المصدر: G3: Genes|Genomes|Genetics
G3
G3, 2021, 11 (2), pp.jkaa070. ⟨10.1093/g3journal/jkaa070⟩

مصطلحات موضوعية: AcademicSubjects/SCI01140, AcademicSubjects/SCI00010, genome annotation pipeline, MESH: Genomics, [SDV]Life Sciences [q-bio], MESH: RNA Interference, MESH: Cryptococcus neoformans, Molecular Sequence Annotation, MESH: Molecular Sequence Annotation, Genomics, Cryptococus deuterogattii, AcademicSubjects/SCI01180, metabolic gene cluster, RNAi, Multigene Family, MESH: Genome, Fungal, Fungal Genetics and Genomics, Cryptococcus neoformans, MESH: Multigene Family, AcademicSubjects/SCI00960, RNA Interference, Genome, Fungal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::66f8773aea430b6adee0234cd3b9163bTest
http://europepmc.org/articles/PMC8022950Test

المؤلفون: Axel Breuer, Axel Cournac, Antoine Vigouroux, Etienne Jean, Adrien Meot, Edgar Oriol, Romain Koszul, Laurent Politis, Arnaud Campeas, Nadège Guiglielmoni, Cyril Matthey-Doret, Lyam Baudry, Vittore F. Scolari, Philippe Henri Chanut, Pierrick Moreau, Rémi Montagne

المساهمون: Régulation spatiale des Génomes - Spatial Regulation of Genomes, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Collège doctoral [Sorbonne universités], Sorbonne Université (SU), ENGIE, Biologie de Synthèse - Synthetic biology, Institut Pasteur [Paris], Département de Biologie Computationnelle - Department of Computational Biology, This work used the computational and storage services (TARS cluster) provided by the IT department at Institut Pasteur, Paris. C.M.-D. was supported by the Pasteur—Paris University (PPU) International PhD Program. A.B. works within the framework of a 'Mécénat Compétence' contract of the company ENGIE. V.S. is the recipient of a Roux-Cantarini Pasteur fellowship. This research was supported by funding to R.K. from the European Research Council under the Horizon 2020 Program (ERC grant agreement 771813) and by ANR JCJC 2019, 'Apollo' allocated to A.C., This work was initiated during a Hackathon between Institut Pasteur scientists and ENGIE engineers. We would like to thank all the people that allow the organisation of this event especially Anne-Gaelle Coutris, Romain Tchertchian and Olivier Gascuel. Julien Mozziconacci, Frédéric Beckouët and all the members of Spatial Regulation of Genomes unit are thanked for stimulating discussions and feedback., ANR-19-CE45-0003,Apollo,Intelligence Artificielle pour atteindre la face cachée des chromosomes(2019), European Project: 771813,SynarchiC, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Collège Doctoral, Institut Pasteur [Paris] (IP), European Project: 771813,ERC-2017-COG,SynarchiC(2018)

المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5795. ⟨10.1038/s41467-020-19562-7⟩
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications, 2020, 11 (1), pp.5795. ⟨10.1038/s41467-020-19562-7⟩

مصطلحات موضوعية: 0301 basic medicine, Computer science, [SDV]Life Sciences [q-bio], General Physics and Astronomy, Genome informatics, Genome, Pattern Recognition, Automated, Workflow, Chromosome conformation capture, chemistry.chemical_compound, 0302 clinical medicine, Chromosomes, Human, MESH: Pattern Recognition, Automated, Computer vision, lcsh:Science, 0303 health sciences, Multidisciplinary, Fungal genetics, MESH: Chromosomes, Fungal, MESH: Saccharomyces cerevisiae, Chromatin, Data processing, Simulated data, MESH: Genome, Fungal, Pattern recognition (psychology), Chromosomes, Fungal, Genome, Fungal, Algorithms, MESH: Computers, Bioinformatics, Science, MESH: Algorithms, Saccharomyces cerevisiae, MESH: Chromosomes, Human, Chromosomes, Article, General Biochemistry, Genetics and Molecular Biology, MESH: Workflow, 03 medical and health sciences, Pattern detection, Code (cryptography), Humans, 030304 developmental biology, Nuclear organization, MESH: Humans, Computers, business.industry, Chromosome, General Chemistry, 030104 developmental biology, chemistry, lcsh:Q, MESH: Chromosomes, Artificial intelligence, business, DNA, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29132112413e0410fbf43fcd2cafa573Test
https://doi.org/10.1038/s41467-020-19562-7Test

المؤلفون: Christophe d'Enfert, Timea Marton, Corinne Maufrais, Mélanie Legrand

المساهمون: Biologie et Pathogénicité fongiques - Fungal Biology and Pathogenicity (BPF), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Paris Diderot, Sorbonne Paris Cité, Paris, France, Université Paris Diderot - Paris 7 (UPD7), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), T.M. is the recipient of a Ph.D. fellowship from the Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (ANR-10-LABX-62-IBEID). We acknowledge support from the French Government’s Investissement d’Avenir program (Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases [ANR10-LABX-62-IBEID])., We are grateful to the members of the Institut Pasteur Mutualized Platform for Microbiology (P2M) for Illumina sequencing., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010)

المصدر: mSphere
MSphere
MSphere, 2020, 5 (5), pp.e00620-20. ⟨10.1128/mSphere.00620-20⟩
mSphere, Vol 5, Iss 5 (2020)

مصطلحات موضوعية: MESH: Gene Editing, MESH: CRISPR-Cas Systems, Molecular Biology and Physiology, [SDV]Life Sciences [q-bio], genome rearrangements, MESH: Transformation, Genetic, MESH: CRISPR-Associated Protein 9, Biology, Microbiology, Genome, Genome engineering, MESH: Homologous Recombination, 03 medical and health sciences, Transformation, Genetic, 0302 clinical medicine, Genome editing, MESH: RNA, Guide, CRISPR-Associated Protein 9, Candida albicans, CRISPR, Homologous Recombination, Molecular Biology, 030304 developmental biology, Gene Editing, Genetics, 0303 health sciences, MESH: Candida albicans, MESH: Genomics, Genomics, Editor's Pick, biology.organism_classification, QR1-502, Corpus albicans, Transformation (genetics), MESH: Genome, Fungal, CRISPR-Cas9, CRISPR-Cas Systems, Genome, Fungal, Homologous recombination, 030217 neurology & neurosurgery, Research Article, RNA, Guide, Kinetoplastida

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6360e1acbd4ef485f7ef66fbe44ff8caTest
https://doi.org/10.1128/msphere.00620-20Test

المؤلفون: José Paulo Sampaio, Gianni Liti, Vassiliki Koufopanou, Timothy A. Mousseau, Susan Lomas, Pedro Almeida, Olga Pronina, Austin Burt

المساهمون: Imperial College London, National Academy of Sciences of Ukraine (NASU), University College of London [London] (UCL), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), University of South Carolina [Columbia], Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Liti, Gianni, Université Nice Sophia Antipolis (... - 2019) (UNS)

المصدر: Genome Biology and Evolution
Genome Biology and Evolution, 2020, 12 (9), pp.1636-1645. ⟨10.1093/gbe/evaa141⟩
Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2020, 12 (9), pp.1636-1645. ⟨10.1093/gbe/evaa141⟩

مصطلحات موضوعية: AcademicSubjects/SCI01140, 0106 biological sciences, Linkage disequilibrium, Lineage (evolution), MESH: Selection, Genetic, 0601 Biochemistry and Cell Biology, 01 natural sciences, Nucleotide diversity, Negative selection, MESH: Genetic Fitness, MESH: Genetic Variation, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Recombination, Genetic, 0303 health sciences, education.field_of_study, biology, Population size, latitude, MESH: Genome, Fungal, MESH: Recombination, Genetic, Genome, Fungal, Research Article, Population, generation time, 010603 evolutionary biology, diversity, Mutation Accumulation, Saccharomyces, 03 medical and health sciences, 0603 Evolutionary Biology, ρ, Genetics, Saccharomyces paradoxus, Selection, Genetic, education, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, MESH: Mutation Accumulation, MESH: Saccharomyces, 0604 Genetics, Generation time, [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE], AcademicSubjects/SCI01130, Genetic Variation, biology.organism_classification, [SDV.MP.MYC] Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, recombination, Evolutionary biology, [SDV.GEN.GPO] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE], Genetic Fitness, divergence, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892b9852d195e29ed4fd4dc25b98b8afTest
http://hdl.handle.net/10044/1/81172Test

المؤلفون: Ana Belén Araúz, Elizabeth L. Berkow, Oliver Kurzai, Christopher H. Heath, Rodney Adam, Sahar Althawadi, Xiao Li, Shawn R. Lockhart, Patricia Escandón, Ronen Ben-Ami, Anastasia P. Litvintseva, Lalitha Gade, Alexandre Alanio, Revathi Gunturu, Kaitlin Forsberg, Ana Alastruey-Izquierdo, Nancy A. Chow, Christina A. Cuomo, Amrita Bharat, Marie Desnos-Ollivier, Dianne Gardam, Belinda Calvo, Ronny Martin, José F. Muñoz, Rory M. Welsh

المساهمون: Centers for Disease Control and Prevention (CDC), Broad Institute [Cambridge], Massachusetts Institute of Technology (MIT)-Harvard University [Cambridge], Aga Khan University Hospital (AKUH), Nairobi, Mycologie moléculaire - Molecular Mycology, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Centre National de Référence Mycoses Invasives et Antifongiques - National Reference Center Invasive Mycoses & Antifungals (CNRMA), Institut Pasteur [Paris], Laboratoire de Parasitologie-Mycologie [CHU Saint Louis, Paris], Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université de Paris (UP), Instituto de Salud Carlos III [Madrid] (ISC), King Faisal Specialist Hospital and Research Centre, Riyadh, Hospital Santo Tomás, Tel Aviv Sourasky Medical Center [Te Aviv], Tel Aviv University [Tel Aviv], Public Health Agency of Canada (PHAC), Universidad del Zulia (LUZ), Instituto Nacional de Salud [Bogota], Fiona Stanley Hospital [Murdoch], Royal Perth Hospital, The University of Western Australia (UWA), Leibniz Institute for Natural Product Research and Infection Biology (Hans Knoell Institute), University of Würzburg = Universität Würzburg, This project has been funded in part with federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under award U19AI110818 to the Broad Institute. C.A.C. is a CIFAR fellow in the Fungal Kingdom Program. This work was also made possible through support from the Advanced Molecular Detection (AMD) initiative at CDC., National Institute of Allergy and Infectious Diseases (United States), Harvard University-Massachusetts Institute of Technology (MIT), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), Université Paris Cité (UPCité), King Faisal Specialist Hospital and Research Centre (KFSH & RC), Tel Aviv University (TAU)

المصدر: mBio
mBio, American Society for Microbiology, 2020, 11 (2), pp.e03364-19. ⟨10.1128/mBio.03364-19⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
mBio, 2020, 11 (2), pp.e03364-19. ⟨10.1128/mBio.03364-19⟩
mBio, Vol 11, Iss 2 (2020)

مصطلحات موضوعية: Azoles, Antifungal Agents, Population genetics, Emerging species, Echinocandins, MESH: Azoles, Molecular clock, Clade, MESH: Phylogeny, Fluconazole, Phylogeny, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Candida, genome analysis, emerging species, 0303 health sciences, education.field_of_study, Molecular Epidemiology, Candida auris, antifungal resistance, Biological Evolution, QR1-502, 3. Good health, Phylogeography, MESH: Phylogeography, MESH: Genome, Fungal, MESH: Fluconazole, Genome, Fungal, MESH: Metagenomics, MESH: Whole Genome Sequencing, Research Article, MESH: Mutation, Population, Genes, Fungal, MESH: Genetics, Population, Context (language use), MESH: Biological Evolution, Ecological and Evolutionary Science, Biology, Microbiology, MESH: Drug Resistance, Fungal, 03 medical and health sciences, Phylogenetics, Drug Resistance, Fungal, MESH: Candida, Virology, Humans, MESH: Molecular Epidemiology, Candidiasis, Invasive, education, 030304 developmental biology, MESH: Humans, Molecular epidemiology, Whole Genome Sequencing, 030306 microbiology, MESH: Echinocandins, population genetics, Antifungal resistance, Genome analysis, MESH: Antifungal Agents, MESH: Candidiasis, Invasive, Genetics, Population, Evolutionary biology, Mutation, Metagenomics, MESH: Genes, Fungal

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6628a6dad67665c57d83087fa738d49eTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-03243537/documentTest

المؤلفون: Frédérique Moyrand, Prashanthi Natarajan, Guilhem Janbon, Jade Sales-Lee, Laura R. Tuck, Frank Feuerbach, Wallace Ewj, Luciana de Oliveira, Hiten D. Madhani, Corinne Maufrais

المساهمون: Centre for Synthetic and Systems Biology (Ssynthsys), University of Edinburgh, Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Biologie des ARN des Pathogènes fongiques - RNA Biology of Fungal Pathogens, Institut Pasteur [Paris] (IP), Department of Biochemistry and Biophysics [San Francisco], University of California (UC), Génétique des Interactions macromoléculaires / Genetics of Macromolecular Interactions, Chan Zuckerberg BioHub [San Francisco, CA], This work in the Madhani lab was supported by grants from the US National Institutes of Health [R01AI120464, R01GM71801 to H.D.M.], H.D.M. is an Investigator of the Chan-Zuckerberg Biohub, E.W.J.W. is a Sir Henry Dale Fellow, supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society [208779/Z/17/Z], L.T. is supported by a Wellcome-University of Edinburgh ISSF3 award, This work in the Janbon lab was supported by an Infect-ERA grant (project Cryptoview). Funding for open access charge: University of Edinburgh., We thank members of the Wallace, Janbon, and Madhani labs for helpful discussions and comments on the manuscript. We thank Juan Mata for sharing intermediate data related to (59). We are grateful to J. Weissman (UCSF) for advice on ribosome profiling. We thank three anonymous reviewers for their helpful comments., Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], University of California, Génétique des Interactions macromoléculaires

المصدر: Wallace, E W J, Maufrais, C, Sales Lee, J, Tuck, L, de Oliveira, L, Feuerbach, F, Moyrand, F, Natarajan, P, Madhani, H D & Janbon, G 2020, ' Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom ', Nucleic Acids Research, vol. 48, no. 5, pp. 2312-2331 . https://doi.org/10.1093/nar/gkaa060Test
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (5), pp.2312-2331. ⟨10.1093/nar/gkaa060⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (5), pp.2312-2331. ⟨10.1093/nar/gkaa060⟩

مصطلحات موضوعية: Kozak consensus sequence, Codon, Initiator, MESH: Gene Expression Regulation, Fungal, MESH: Saccharomyces cerevisiae / metabolism, Ribosome, 0302 clinical medicine, Start codon, Gene Expression Regulation, Fungal, MESH: Neurospora crassa / metabolism, Candida albicans, MESH: Schizosaccharomyces / metabolism, Peptide Chain Initiation, Translational, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Genetics, 0303 health sciences, Chromosome Mapping, Translation (biology), MESH: Codon, Initiator / chemistry, MESH: Candida albicans / genetics, Transfer RNA, Genome, Fungal, MESH: Genome, Fungal, MESH: Codon, Initiator / metabolism, MESH: Peptide Chain Initiation, Translational, Context (language use), Saccharomyces cerevisiae, Data Resources and Analyses, MESH: Amino Acyl-tRNA Synthetases / genetics, Biology, Amino Acyl-tRNA Synthetases, Open Reading Frames, 03 medical and health sciences, Species Specificity, Schizosaccharomyces, MESH: Neurospora crassa / genetics, MESH: Species Specificity, Gene, MESH: Cryptococcus / metabolism, 030304 developmental biology, [SDV.GEN]Life Sciences [q-bio]/Genetics, Neurospora crassa, MESH: Schizosaccharomyces / genetics, MESH: Cryptococcus / genetics, MESH: Open Reading Frames, MESH: Saccharomyces cerevisiae / genetics, Cryptococcus, Open reading frame, MESH: Amino Acyl-tRNA Synthetases / metabolism, MESH: Chromosome Mapping, MESH: Candida albicans / metabolism, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf61a7e41b710769c98f2c49ddc7d2bfTest
https://www.pure.ed.ac.uk/ws/files/133847580/gkaa060.pdfTest

المؤلفون: Eugene Gladyshev, Tinh-Suong Nguyen

المساهمون: Epigénomique fongique - Fungal Epigenomics, Institut Pasteur [Paris] (IP), The work was supported by grants from the Agence Nationale de la Recherche (10-LABX-0062) and Fondation pour la Recherche Médicale (AJE20180539525)., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Institut Pasteur [Paris]

المصدر: Fungal Genetics and Biology
Fungal Genetics and Biology, 2020, 136, pp.103316. ⟨10.1016/j.fgb.2019.103316⟩
Fungal Genetics and Biology, Elsevier, 2020, 136, pp.103316. ⟨10.1016/j.fgb.2019.103316⟩

مصطلحات موضوعية: Photomicrography, TetR, Operator Regions, Genetic, MESH: Genes, Synthetic, FROS, MESH: Neurospora crassa, MESH: Tetracycline, Green fluorescent protein, chemistry.chemical_compound, Gene Expression Regulation, Fungal, Genes, Synthetic, Fluorescence microscope, Homologous Recombination, 0303 health sciences, biology, Cell biology, DNA-Binding Proteins, MESH: Repressor Proteins, MESH: Genome, Fungal, MESH: Fungal Proteins, Genome, Fungal, Fluorescent repressor operator system, MESH: Gene Expression Regulation, Fungal, MESH: Photomicrography, Recombinant Fusion Proteins, Genes, Fungal, Microbiology, Neurospora, Neurospora crassa, Fungal Proteins, MESH: Homologous Recombination, 03 medical and health sciences, Genetics, Homologous chromosome, MESH: Recombinant Fusion Proteins, Point Mutation, Gene, tetO, Repetitive Sequences, Nucleic Acid, 030304 developmental biology, MESH: Point Mutation, MESH: Repetitive Sequences, Nucleic Acid, 030306 microbiology, Point mutation, fungi, MESH: Saporins, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, Tetracycline, biology.organism_classification, Saporins, Repressor Proteins, chemistry, RIP, MESH: Operator Regions, Genetic, Repeat-induced point mutation, MESH: Genes, Fungal, MESH: DNA-Binding Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81a2b1fb27dab10d68f603a8b275d78Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-03261456/documentTest

المؤلفون: Isabelle P. Oswald, Emilien L. Jamin, Thaïs Hautbergue, Olivier Puel, Laurent Debrauwer

المساهمون: ToxAlim (ToxAlim), Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, MetaboHUB, Analyse de Xénobiotiques, Identification, Métabolisme (E20 Metatoul-AXIOM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-MetaToul-MetaboHUB, Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Biosynthèse & Toxicité des Mycotoxines (ToxAlim-BioToMyc), This study was co-funded by INRA and French Minister of Higher Education and Research in the context of a project supported by French National Agency of Research (ANR-15-CE21-0010-21Newmyco), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole d'Ingénieurs de Purpan (INPT - EI Purpan), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Recherche Agronomique (INRA)-MetaToul-MetaboHUB, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de la Santé et de la Recherche Médicale (INSERM), ANR-15-CE21-0010,Newmyco,Metabolome de deux contaminants fongiques du blé d'importance majeure: identification de nouveaux métabolites toxiques(2015), ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-MetaboHUB-MetaToul, Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), OSWALD, Isabelle, Metabolome de deux contaminants fongiques du blé d'importance majeure: identification de nouveaux métabolites toxiques - - Newmyco2015 - ANR-15-CE21-0010 - AAPG2015 - VALID, Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation - - METABOHUB2011 - ANR-11-INBS-0010 - INBS - VALID

المصدر: Natural Product Reports
Natural Product Reports, Royal Society of Chemistry, 2018, 35 (2), pp.147-173. ⟨10.1039/c7np00032d⟩
Natural Product Reports, 2018, 35 (2), pp.147-173. ⟨10.1039/c7np00032d⟩

مصطلحات موضوعية: Proteomics, 0301 basic medicine, MESH: Isotope Labeling, MESH: Genomics / methods, [SDV]Life Sciences [q-bio], Secondary Metabolism, Biochemistry, Gene Knockout Techniques, Drug Discovery, Data Mining, MESH: Gene Knockout Techniques, Animal health, Drug discovery, Culture environment, Genomics, MESH: Proteomics / methods, [SDV.TOX] Life Sciences [q-bio]/Toxicology, MESH: Secondary Metabolism, [SDV.TOX.TVM] Life Sciences [q-bio]/Toxicology/Vegetal toxicology and mycotoxicology, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Isotope Labeling, Multigene Family, MESH: Genome, Fungal, Identification (biology), Genome, Fungal, MESH: Metabolomics / methods, Emerging technologies, [SDV.TOX.TVM]Life Sciences [q-bio]/Toxicology/Vegetal toxicology and mycotoxicology, [SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chain, Computational biology, Biology, 03 medical and health sciences, Metabolomics, MESH: Computer Simulation, MESH: Drug Discovery, Computer Simulation, MESH: Biological Products / metabolism, Secondary metabolism, MESH: Biological Products / isolation & purification, Biological Products, [SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, MESH: Fungi / metabolism, Organic Chemistry, [SDV.BA.MVSA] Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, Fungi, MESH: Fungi / genetics, MESH: Data Mining / methods, 030104 developmental biology, [SDV.TOX.TCA] Life Sciences [q-bio]/Toxicology/Toxicology and food chain, MESH: Multigene Family

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488311aeb48b0d66affe18db74ac609dTest
https://doi.org/10.1039/c7np00032dTest