المؤلفون: Chen, Huimei, Moreno-Moral, Aida, Pesce, Francesco, Devapragash, Nithya, Mancini, Massimiliano, Heng, Ee Ling, Rotival, Maxime, Srivastava, Prashant, K, Harmston, Nathan, Shkura, Kirill, Rackham, Owen, J L, Yu, Wei-Ping, Sun, Xi-Ming, Gui Zhen Tee, Nicole, Li San Tan, Elisabeth, Barton, Paul, J R, Felkin, Leanne, E, Lara-Pezzi, Enrique, Angelini, Gianni, Beltrami, Cristina, Pravenec, Michal, Schafer, Sebastian, Bottolo, Leonardo, Hubner, Norbert, Emanueli, Costanza, Cook, Stuart, Petretto, Enrico

المساهمون: Cardiovascular and Metabolic Disorders Singapor (cvmd), Duke-NUS Medical School Singapore, Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Ospedale San Giovanni di Dio, Firenze, National Heart and Lung Institute London (NHLI), Imperial College London-Royal Brompton and Harefield NHS Foundation Trust, Génétique Evolutive Humaine - Human Evolutionary Genetics, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Faculty of Medicine London, UK, Imperial College London, Agency for science, technology and research Singapore (A*STAR), Institute of Molecular and Cell Biology, National University of Singapore (NUS)-Agency for science, technology and research Singapore (A*STAR), MRC London Institute of Medical Sciences (LMC), National Heart Centre Singapore (NHCS), Royal Brompton and Harefield NHS Foundation Trust, Cardiovascular Research Centre London, Centro Nacional de Investigaciones Cardiovasculares Carlos III Madrid, Spain (CNIC), Instituto de Salud Carlos III Madrid (ISC), University of Bristol Bristol, Institute of Physiology Prague, Czech Academy of Sciences Prague (CAS), University of Cambridge UK (CAM), The Alan Turing Institute, MRC Biostatistics Unit Cambridge, UK, Max Delbrück Center for Molecular Medicine Berlin (MDC), Helmholtz-Gemeinschaft = Helmholtz Association, German Center for Cardiovascular Research (DZHK), Berlin Institute of Health (BIH), Charité - UniversitätsMedizin = Charité - University Hospital Berlin, The research was primarily supported by National Medical Research Council (NMRC) Singapore grant NMRC/CBRG/0106/2016 (to E.P.) and the British Heart Foundation (BHF) Ph.D. Studentship grant FS/11/25/28740 (to E.P). We acknowledge additional funding support from European Union FP7 CardioNeT-ITN-289600 (to E.L.-P., S.A.C., and P.J.R.B.), Heart Research UK (to P.J.R.B.), NIHR CV BRU of Royal Brompton and Harefield, NHS Foundation Trust (to S.A.C. and P.J.R.B.), BHF (to S.A.C.), Leducq Foundation (to S.A.C.), MRC UK (to S.A.C.), BHF Program Grant no. RG/15/5/31446 (to C.E. and E.P.). M.P. was supported by Praemium Academiae award of the Czech Academy of Sciences and grant 14-36804G from the Czech Science Foundation., We wish to thank Dr. Jacques Behmoaras for contributing critical and constructive comments to the manuscript., European Project: 289600,EC:FP7:PEOPLE,FP7-PEOPLE-2011-ITN,CARDIONET(2012)

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: Ubiquitin ligases, Cardiomyopathies, MESH: Adolescent, MESH: Adult, MESH: Fibrosis / genetics, MESH: Fibrosis / metabolism, MESH: Mice, Transgenic, MESH: Gene Regulatory Networks, MESH: Genetic Predisposition to Disease* / genetics, MESH: Heart Diseases / genetics, MESH: Heart Diseases / metabolism, MESH: Humans, MESH: Male, MESH: Ubiquitin-Protein Ligases / metabolism, MESH: Middle Aged, MESH: Aged, MESH: Protein Isoforms, MESH: Smad2 Protein / genetics, MESH: Smad2 Protein / metabolism, MESH: Transforming Growth Factor beta / metabolism, MESH: Ubiquitin-Protein Ligases / genetics, MESH: Young Adult, MESH: Gene Expression Regulation, MESH: Animals, MESH: Cardiomyopathies / genetics, MESH: Cardiomyopathies / metabolism, MESH: Extracellular Matrix Proteins / metabolism, MESH: Female, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31399586; info:eu-repo/grantAgreement/EC/FP7/289600/EU/Translational Training network on the Cellular and Molecular Bases of Heart Homeostasis and Repair/CARDIONET; pasteur-02868982; https://pasteur.hal.science/pasteur-02868982Test; https://pasteur.hal.science/pasteur-02868982/documentTest; https://pasteur.hal.science/pasteur-02868982/file/Chen_Nature%20Communication_2019.pdfTest; PUBMED: 31399586; PUBMEDCENTRAL: PMC6689010

الإتاحة: https://doi.org/10.1038/s41467-019-11551-9Test
https://pasteur.hal.science/pasteur-02868982Test
https://pasteur.hal.science/pasteur-02868982/documentTest
https://pasteur.hal.science/pasteur-02868982/file/Chen_Nature%20Communication_2019.pdfTest

المؤلفون: Surendran, Praveen, Feofanova, Elena, Lahrouchi, Najim, Ntalla, Ioanna, Karthikeyan, Savita, Cook, James, Chen, Lingyan, Mifsud, Borbala, Yao, Chen, Kraja, Aldi, Cartwright, James, Hellwege, Jacklyn, Giri, Ayush, Tragante, Vinicius, Thorleifsson, Gudmar, Liu, Dajiang, Prins, Bram, Stewart, Isobel, Cabrera, Claudia, Eales, James, Akbarov, Artur, Auer, Paul, Bielak, Lawrence, Bis, Joshua, Braithwaite, Vickie, Brody, Jennifer, Daw, E. Warwick, Warren, Helen, Drenos, Fotios, Nielsen, Sune Fallgaard, Faul, Jessica, Fauman, Eric, Fava, Cristiano, Ferreira, Teresa, Foley, Christopher, Franceschini, Nora, Gao, He, Giannakopoulou, Olga, Giulianini, Franco, Gudbjartsson, Daniel, Guo, Xiuqing, Harris, Sarah, Havulinna, Aki, Helgadottir, Anna, Huffman, Jennifer, Hwang, Shih-Jen, Kanoni, Stavroula, Kontto, Jukka, Larson, Martin, Li-Gao, Ruifang, Lindström, Jaana, Lotta, Luca, Lu, Yingchang, Luan, Jian’an, Mahajan, Anubha, Malerba, Giovanni, Masca, Nicholas, Mei, Hao, Menni, Cristina, Mook-Kanamori, Dennis, Mosen-Ansorena, David, Müller-Nurasyid, Martina, Paré, Guillaume, Paul, Dirk, Perola, Markus, Poveda, Alaitz, Rauramaa, Rainer, Richard, Melissa, Richardson, Tom, Sepúlveda, Nuno, Sim, Xueling, Smith, Albert, Smith, Jennifer, Staley, James, Stanáková, Alena, Sulem, Patrick, Thériault, Sébastien, Thorsteinsdottir, Unnur, Trompet, Stella, Varga, Tibor, Velez Edwards, Digna, Veronesi, Giovanni, Weiss, Stefan, Willems, Sara, Yao, Jie, Young, Robin, Yu, Bing, Zhang, Weihua, Zhao, Jing-Hua, Zhao, Wei, Evangelou, Evangelos, Aeschbacher, Stefanie, Asllanaj, Eralda, Blankenberg, Stefan, Bonnycastle, Lori, Bork-Jensen, Jette, Brandslund, Ivan, Braund, Peter, Burgess, Stephen, Cho, Kelly, Christensen, Cramer, Connell, John, Mutsert, Renée De, Dominiczak, Anna, Dörr, Marcus, Eiriksdottir, Gudny, Farmaki, Aliki-Eleni, Gaziano, J. Michael, Grarup, Niels, Grove, Megan, Hallmans, Göran, Hansen, Torben, Have, Christian, Heiss, Gerardo, Jørgensen, Marit, Jousilahti, Pekka, Kajantie, Eero, Kamat, Mihir, Käräjämäki, Annemari, Karpe, Fredrik, Koistinen, Heikki, Kovesdy, Csaba, Kuulasmaa, Kari, Laatikainen, Tiina, Lannfelt, Lars, Lee, I-Te, Lee, Wen-Jane, de Boer, Rudolf, van der Harst, Pim, van der Meer, Peter, Verweij, Niek, Linneberg, Allan, Martin, Lisa, Moitry, Marie, Nadkarni, Girish, Neville, Matt, Palmer, Colin, Papanicolaou, George, Pedersen, Oluf, Peters, James, Poulter, Neil, Rasheed, Asif, Rasmussen, Katrine, Rayner, N. William, Mägi, Reedik, Renström, Frida, Rettig, Rainer, Rossouw, Jacques, Schreiner, Pamela, Sever, Peter, Sigurdsson, Emil, Skaaby, Tea, Sun, Yan, Sundstrom, Johan, Thorgeirsson, Gudmundur, Esko, Tõnu, Trabetti, Elisabetta, Tsao, Philip, Tuomi, Tiinamaija, Turner, Stephen, Tzoulaki, Ioanna, Vaartjes, Ilonca, Vergnaud, Anne-Claire, Willer, Cristen, Wilson, Peter, Witte, Daniel, Yonova-Doing, Ekaterina, Zhang, He, Aliya, Naheed, Almgren, Peter, Amouyel, Philippe, Asselbergs, Folkert, Barnes, Michael, Blakemore, Alexandra, Boehnke, Michael, Bots, Michiel, Bottinger, Erwin, Buring, Julie, Chambers, John, Chen, Yii-Der Ida, Chowdhury, Rajiv, Conen, David, Correa, Adolfo, Davey Smith, George, Boer, Rudolf, Deary, Ian, Dedoussis, George, Deloukas, Panos, Di Angelantonio, Emanuele, Elliott, Paul, Butterworth, Adam, Danesh, John, Langenberg, Claudia, Mccarthy, Mark, Franks, Paul, Rolandsson, Olov, Wareham, Nicholas, Felix, Stephan, Ferrières, Jean, Ford, Ian, Fornage, Myriam, Franks, Stephen, Frossard, Philippe, Gambaro, Giovanni, Gaunt, Tom, Groop, Leif, Gudnason, Vilmundur, Harris, Tamara, Hayward, Caroline, Hennig, Branwen, Herzig, Karl-Heinz, Ingelsson, Erik, Tuomilehto, Jaakko, Järvelin, Marjo-Riitta, Jukema, J. Wouter, Kardia, Sharon, Kee, Frank, Kooner, Jaspal, Kooperberg, Charles, Launer, Lenore, Lind, Lars, Loos, Ruth, Majumder, Abdulla Al Shafi., Laakso, Markku, Melander, Olle, Mohlke, Karen, Murray, Alison, Nordestgaard, Børge Grønne, Orho-Melander, Marju, Packard, Chris, Padmanabhan, Sandosh, Palmas, Walter, Polasek, Ozren, Porteous, David, Prentice, Andrew, Province, Michael, Relton, Caroline, Rice, Kenneth, Ridker, Paul, Rosendaal, Frits, Rotter, Jerome, Rudan, Igor, Salomaa, Veikko, Samani, Nilesh, Sattar, Naveed, Sheu, Wayne H.-H., Smith, Blair, Soranzo, Nicole, Spector, Timothy, Starr, John, Sebert, Sylvain, Taylor, Kent, Lakka, Timo, Timpson, Nicholas, Tobin, Martin, Zeggini, Eleftheria, Ramachandran, Vasan, Virtamo, Jarmo, Völker, Uwe, Weir, David, Charchar, Fadi, Edwards, Digna, Edwards, Todd, Hung, Adriana, O’donnell, Christopher, Tomaszewski, Maciej, Caulfield, Mark, Holm, Hilma, Lindgren, Cecilia, Liu, Chunyu, Manning, Alisa, Morris, Andrew, Morrison, Alanna, Psaty, Bruce, Saleheen, Danish, Stefansson, Kari, Boerwinkle, Eric, Chasman, Daniel, Levy, Daniel, Newton-Cheh, Christopher, Munroe, Patricia, Howson, Joanna

المساهمون: University of Cambridge UK (CAM), The University of Texas Health Science Center at Houston (UTHealth), Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School Boston (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital Boston, Massachusetts General Hospital Boston, Amsterdam UMC - Amsterdam University Medical Center, Queen Mary University of London (QMUL), University of Liverpool, William Harvey Research Institute, Barts and the London Medical School, Hamad Bin Khalifa University (HBKU), Framingham Heart Study, Boston University Boston (BU)-National Heart, Lung, and Blood Institute Bethesda (NHLBI), National Heart, Lung, and Blood Institute Bethesda (NHLBI), Washington University School of Medicine Saint Louis, MO, Vanderbilt University Medical Center Nashville, Vanderbilt University Nashville, University Medical Center Utrecht, Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 (RID-AGE), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Equipe Vieillissement (CERPOP), Centre d'Epidémiologie et de Recherche en santé des POPulations (CERPOP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: ISSN: 1061-4036.

مصطلحات موضوعية: MESH: Blood Pressure / genetics, MESH: GATA5 Transcription Factor / genetics, MESH: Polymorphism, Single Nucleotide / genetics, MESH: Gene Frequency / genetics, MESH: Genetic Predisposition to Disease / genetics, MESH: Genome-Wide Association Study, MESH: Genotype, MESH: Humans, MESH: Hypertension / genetics, MESH: Mutation / genetics, MESH: Phospholipase C beta / genetics, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33230300; hal-04178533; https://hal.science/hal-04178533Test; PUBMED: 33230300; PUBMEDCENTRAL: PMC7610439

الإتاحة: https://doi.org/10.1038/s41588-020-00713-xTest
https://hal.science/hal-04178533Test

المؤلفون: Cristina Beltrami, Owen J. L. Rackham, Costanza Emanueli, Nithya Devapragash, Wei-Ping Yu, Xi-Ming Sun, Stuart A. Cook, Norbert Hubner, Francesco Pesce, Ee Ling Heng, Elisabeth Tan, Aida Moreno-Moral, Enrique Lara-Pezzi, Gianni D Angelini, Enrico Petretto, Huimei Chen, Paul J.R. Barton, Nathan Harmston, Michal Pravenec, Sebastian Schafer, Maxime Rotival, Nicole Tee, Massimilano Mancini, Leanne E. Felkin, Leonardo Bottolo, Prashant K. Srivastava, Kirill Shkura

المساهمون: Cardiovascular and Metabolic Disorders [Singapor] (cvmd), Duke-NUS Medical School [Singapore], Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA), Ospedale San Giovanni di Dio, Firenze, National Heart and Lung Institute [London] (NHLI), Imperial College London-Royal Brompton and Harefield NHS Foundation Trust, Génétique Evolutive Humaine - Human Evolutionary Genetics, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Faculty of Medicine [London, UK], Imperial College London, Agency for science, technology and research [Singapore] (A*STAR), Institute of Molecular and Cell Biology, National University of Singapore (NUS)-Agency for science, technology and research [Singapore] (A*STAR), MRC London Institute of Medical Sciences (LMC), National Heart Centre Singapore (NHCS), Royal Brompton and Harefield NHS Foundation Trust, Cardiovascular Research Centre [London], Centro Nacional de Investigaciones Cardiovasculares Carlos III [Madrid, Spain] (CNIC), Instituto de Salud Carlos III [Madrid] (ISC), University of Bristol [Bristol], Institute of Physiology [Prague], Czech Academy of Sciences [Prague] (CAS), University of Cambridge [UK] (CAM), The Alan Turing Institute, MRC Biostatistics Unit [Cambridge, UK], Max Delbrück Center for Molecular Medicine [Berlin] (MDC), Helmholtz-Gemeinschaft = Helmholtz Association, German Center for Cardiovascular Research (DZHK), Berlin Institute of Health (BIH), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], The research was primarily supported by National Medical Research Council (NMRC) Singapore grant NMRC/CBRG/0106/2016 (to E.P.) and the British Heart Foundation (BHF) Ph.D. Studentship grant FS/11/25/28740 (to E.P). We acknowledge additional funding support from European Union FP7 CardioNeT-ITN-289600 (to E.L.-P., S.A.C., and P.J.R.B.), Heart Research UK (to P.J.R.B.), NIHR CV BRU of Royal Brompton and Harefield, NHS Foundation Trust (to S.A.C. and P.J.R.B.), BHF (to S.A.C.), Leducq Foundation (to S.A.C.), MRC UK (to S.A.C.), BHF Program Grant no. RG/15/5/31446 (to C.E. and E.P.). M.P. was supported by Praemium Academiae award of the Czech Academy of Sciences and grant 14-36804G from the Czech Science Foundation., We wish to thank Dr. Jacques Behmoaras for contributing critical and constructive comments to the manuscript., European Project: 289600,EC:FP7:PEOPLE,FP7-PEOPLE-2011-ITN,CARDIONET(2012), Moreno-Moral, Aida [0000-0002-8155-3146], Barton, Paul J. R. [0000-0002-1165-7767], Schafer, Sebastian [0000-0002-6909-8275], Bottolo, Leonardo [0000-0002-6381-2327], Cook, Stuart A. [0000-0001-6628-194X], Petretto, Enrico [0000-0003-2163-5921], Apollo - University of Cambridge Repository, National Medical Research Council (Singapur), British Heart Foundation, Unión Europea. Comisión Europea, National Institutes of Health (Estados Unidos), Czech Science Foundation, Fondation Leducq, NHS Foundation Trusth, University of Bari Aldo Moro (UNIBA), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Leducq Foundation for Cardiovascular Research, Commission of the European Communities, Heart Research UK, Medical Research Council (MRC), Barton, Paul JR [0000-0002-1165-7767], Cook, Stuart A [0000-0001-6628-194X]

المصدر: Nature Communications
Nature Communications, 2019, 10 (1), pp.3616. ⟨10.1038/s41467-019-11551-9⟩
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Chen, H, Moreno-Moral, A, Pesce, F, Devapragash, N, Mancini, M, Heng, E L, Rotival, M, Srivastava, P K, Harmston, N, Shkura, K, Rackham, O J L, Yu, W P, Sun, X M, Tee, N G Z, Tan, E L S, Barton, P J R, Felkin, L E, Lara-Pezzi, E, Angelini, G, Beltrami, C, Pravenec, M, Schafer, S, Bottolo, L, Hubner, N, Emanueli, C, Cook, S A & Petretto, E 2019, ' WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signalling ', Nature Communications, vol. 10, 3616 . https://doi.org/10.1038/s41467-019-11551-9Test
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3616. ⟨10.1038/s41467-019-11551-9⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: Male, 45/43, BLOOD-PRESSURE, 02 engineering and technology, MESH: Protein Isoforms, MESH: Heart Diseases / genetics, Mice, Transforming Growth Factor beta, 42/44, Fibrosis, Protein Isoforms, Medicine, MESH: Animals, lcsh:Science, MESH: Ubiquitin-Protein Ligases / genetics, MESH: Fibrosis / metabolism, MESH: Genetic Predisposition to Disease* / genetics, GENE-EXPRESSION, Regulation of gene expression, Extracellular Matrix Proteins, MESH: Middle Aged, MESH: Fibrosis / genetics, TGF-BETA, MESH: Heart Diseases / metabolism, MESH: Ubiquitin-Protein Ligases / metabolism, 3. Good health, Cell biology, Ubiquitin ligase, FIBROBLAST, MESH: Young Adult, Science & Technology - Other Topics, 64/60, Cardiomyopathies, 0210 nano-technology, Cardiac function curve, Science, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, REVEALS, Humans, Aged, MESH: Adolescent, Science & Technology, MESH: Humans, [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE], IDENTIFICATION, MESH: Smad2 Protein / metabolism, MESH: Extracellular Matrix Proteins / metabolism, MESH: Adult, MESH: Cardiomyopathies / metabolism, medicine.disease, 030104 developmental biology, Cardiovascular and Metabolic Diseases, E3 UBIQUITIN LIGASE, RAT, DETERMINANT, lcsh:Q, Myocardial fibrosis, MESH: Female, 0301 basic medicine, Cardiac fibrosis, General Physics and Astronomy, Smad2 Protein, Gene Regulatory Networks, 13/89, MESH: Aged, MESH: Transforming Growth Factor beta / metabolism, Multidisciplinary, biology, MESH: Smad2 Protein / genetics, article, Middle Aged, MESH: Cardiomyopathies / genetics, 021001 nanoscience & nanotechnology, 692/4019/592/75/74, MESH: Gene Expression Regulation, Multidisciplinary Sciences, Centre for Surgical Research, HEART-FAILURE, Female, 38/39, Adult, Adolescent, Heart Diseases, MESH: Mice, Transgenic, Ubiquitin-Protein Ligases, Mice, Transgenic, 14/32, 82/80, Young Adult, Animals, Genetic Predisposition to Disease, 14/35, MESH: Mice, Pressure overload, business.industry, General Chemistry, MESH: Male, Gene Expression Regulation, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, Ubiquitin ligases, Heart failure, 13/51, biology.protein, 631/45/474/2073, MESH: Gene Regulatory Networks, business

وصف الملف: application/pdf; text; application/zip; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9a8eae768aaa77cac0482318b75243Test
https://doi.org/10.1038/s41467-019-11551-9Test

المؤلفون: Akil, Abdellah, Ezzikouri, Sayeh, El Feydi, Abdellah Essaid, Benazzouz, Mustapha, Afifi, Rajaa, Diagne, Ama Gassama, Benjouad, Aziz, Dejean, Anne, Pineau, Pascal, Benjelloun, Soumaya

المساهمون: Laboratoire des Hépatites Virales Casablanca, Maroc (LHV), Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université Mohammed V de Rabat Agdal (UM5), CHU Ibn-Sina Rabat (CHUIS), Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by Pasteur Institute of Morocco and the Pasteur Institutes International Network (RIIP)., The authors would like to acknowledge all patients for their participation in this study.

المصدر: ISSN: 1877-7821 ; Cancer Epidemiology ; https://pasteur.hal.science/pasteur-02863321Test ; Cancer Epidemiology, 2012, 36 (5), pp.e300-e305. ⟨10.1016/j.canep.2012.05.011⟩.

مصطلحات موضوعية: EP300, PCAF, Liver cancer, Genetic susceptibility, Histone acetyltransferases, MESH: Carcinoma, Hepatocellular / epidemiology, Hepatocellular / genetics, MESH: Liver Neoplasms / epidemiology, MESH: Liver Neoplasms / genetics, MESH: Male, MESH: Markov Chains, MESH: Middle Aged, MESH: Morocco / epidemiology, MESH: Mutation, Missense, MESH: Odds Ratio, MESH: Polymorphism, Genetic, Single Nucleotide, MESH: Case-Control Studies, MESH: Risk Factors, MESH: Sex Distribution, MESH: Sex Factors, MESH: p300-CBP Transcription Factors / genetics, MESH: Chromosomal Instability / genetics, MESH: E1A-Associated p300 Protein / genetics, MESH: Female, MESH: Gene Frequency, MESH: Genetic Predisposition to Disease / genetics

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/22709982; pasteur-02863321; https://pasteur.hal.science/pasteur-02863321Test; PUBMED: 22709982

الإتاحة: https://doi.org/10.1016/j.canep.2012.05.011Test
https://pasteur.hal.science/pasteur-02863321Test

المؤلفون: M. Benazzouz, Aziz Benjouad, Abdellah Akil, Rajaa Afifi, Sayeh Ezzikouri, Pascal Pineau, Abdellah Essaid El Feydi, Soumaya Benjelloun, Ama Gassama Diagne, Anne Dejean

المساهمون: Laboratoire des Hépatites Virales [Casablanca, Maroc] (LHV), Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université Mohammed V de Rabat [Agdal] (UM5), CHU Ibn-Sina [Rabat] (CHUIS), Organisation Nucléaire et Oncogenèse / Nuclear Organization and Oncogenesis, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by Pasteur Institute of Morocco and the Pasteur Institutes International Network (RIIP)., The authors would like to acknowledge all patients for their participation in this study., Université Mohammed V, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Cancer Epidemiology
Cancer Epidemiology, 2012, 36 (5), pp.e300-e305. ⟨10.1016/j.canep.2012.05.011⟩
Cancer Epidemiology, Elsevier, 2012, 36 (5), pp.e300-e305. ⟨10.1016/j.canep.2012.05.011⟩

مصطلحات موضوعية: Male, Cancer Research, Epidemiology, MESH: Genotype, 0302 clinical medicine, Gene Frequency, MESH: Risk Factors, Risk Factors, Genotype, MESH: Liver Neoplasms / genetics, Odds Ratio, p300-CBP Transcription Factors, EP300, 0303 health sciences, education.field_of_study, MESH: Middle Aged, MESH: Polymorphism, Single Nucleotide, MESH: Sex Distribution, Liver Neoplasms, MESH: E1A-Associated p300 Protein / genetics, Middle Aged, MESH: Case-Control Studies, Markov Chains, 3. Good health, Morocco, MESH: Chromosomal Instability / genetics, Oncology, PCAF, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Female, Liver cancer, MESH: Carcinoma, Hepatocellular / epidemiology, Carcinoma, Hepatocellular, Population, Mutation, Missense, [SDV.CAN]Life Sciences [q-bio]/Cancer, Polymorphism, Single Nucleotide, 03 medical and health sciences, MESH: Morocco / epidemiology, MESH: Polymorphism, Genetic, Sex Factors, MESH: Sex Factors, MESH: Markov Chains, MESH: p300-CBP Transcription Factors / genetics, Chromosomal Instability, medicine, Genetic predisposition, Genetic susceptibility, MESH: Gene Frequency, Humans, Genetic Predisposition to Disease, MESH: Genetic Predisposition to Disease / genetics, Sex Distribution, education, 030304 developmental biology, MESH: Mutation, Missense, MESH: Humans, Polymorphism, Genetic, business.industry, MESH: Carcinoma, Hepatocellular / genetics, Cancer, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, digestive system diseases, MESH: Male, MESH: Odds Ratio, Histone acetyltransferases, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, MESH: Liver Neoplasms / epidemiology, Case-Control Studies, Cancer research, business, MESH: Female, E1A-Associated p300 Protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1a22fd93c751047ddc0d7af3d618b1Test
https://pubmed.ncbi.nlm.nih.gov/22709982Test

المؤلفون: Ezzikouri, Sayeh, El Feydi, Abdellah Essaid, El Kihal, Latifa, Afifi, Rajae, Benazzouz, Mustapha, Hassar, Mohammed, Chafik, Abdelaziz, Pineau, Pascal, Benjelloun, Soumaya

المساهمون: Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP), CHU Ibn-Sina Rabat (CHUIS), Laboratoire d'Anthropogénétique et Biostatistique El Jadida, Maroc, Faculté des Sciences El Jadida. Maroc, Université Chouaib Doukkali (UCD)-Université Chouaib Doukkali (UCD), Organisation Nucléaire et Oncogenèse, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), We thank the Direction des Programmes Transversaux de Recherches of the Institut Pasteur, Paris for their financial support (PTR n° 130)., The authors would like to acknowledge all patients for their participation in this study, We are particularly grateful to Benoit Robert and Michele Joliy for their advice and encouragement. We also thank Nathalie Jolly and Christine Sadorge for their skillful expertise in Medical Research Protocol elaboration

المصدر: ISSN: 0188-4409 ; Archives of Medical Research ; https://pasteur.hal.science/pasteur-02870414Test ; Archives of Medical Research, 2008, 39 (2), pp.236-241. ⟨10.1016/j.arcmed.2007.09.006⟩.

مصطلحات موضوعية: S mutation, Z mutation, HFE mutations, Hepatocellular carcinoma, MESH: Aged, MESH: Alleles, MESH: Homozygote, MESH: Humans, MESH: Liver Neoplasms / epidemiology, MESH: Liver Neoplasms / genetics, MESH: Male, MESH: Membrane Proteins / genetics, MESH: Middle Aged, MESH: Morocco, MESH: Mutation, Missense, MESH: Prevalence, MESH: Arabs, MESH: Retrospective Studies, MESH: alpha 1-Antitrypsin / genetics, MESH: Carcinoma, Hepatocellular / epidemiology, Hepatocellular / genetics, MESH: Female, MESH: Genetic Predisposition to Disease / genetics, MESH: Hemochromatosis Protein, MESH: Heterozygote, MESH: Histocompatibility Antigens Class I / genetics, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, [SDV.CAN]Life Sciences [q-bio]/Cancer

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/18164971; pasteur-02870414; https://pasteur.hal.science/pasteur-02870414Test; PUBMED: 18164971

الإتاحة: https://doi.org/10.1016/j.arcmed.2007.09.006Test
https://pasteur.hal.science/pasteur-02870414Test

المؤلفون: Latifa El Kihal, Rajae Afifi, Mohammed Hassar, Pascal Pineau, M. Benazzouz, Sayeh Ezzikouri, Abdellah Essaid El Feydi, Abdelaziz Chafik, Soumaya Benjelloun

المساهمون: Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP), CHU Ibn-Sina [Rabat] (CHUIS), Laboratoire d'Anthropogénétique et Biostatistique [El Jadida, Maroc], Faculté des Sciences [El Jadida. Maroc], Université Chouaib Doukkali (UCD)-Université Chouaib Doukkali (UCD), Organisation Nucléaire et Oncogenèse, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), We thank the Direction des Programmes Transversaux de Recherches of the Institut Pasteur, Paris for their financial support (PTR n° 130)., The authors would like to acknowledge all patients for their participation in this study, We are particularly grateful to Benoit Robert and Michele Joliy for their advice and encouragement. We also thank Nathalie Jolly and Christine Sadorge for their skillful expertise in Medical Research Protocol elaboration, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Archives of Medical Research
Archives of Medical Research, Elsevier, 2008, 39 (2), pp.236-241. ⟨10.1016/j.arcmed.2007.09.006⟩
Archives of Medical Research, 2008, 39 (2), pp.236-241. ⟨10.1016/j.arcmed.2007.09.006⟩

مصطلحات موضوعية: Male, Pathology, Hepatocellular carcinoma, MESH: Membrane Proteins / genetics, medicine.disease_cause, Gastroenterology, Loss of heterozygosity, 0302 clinical medicine, Prevalence, MESH: Liver Neoplasms / genetics, MESH: Hemochromatosis Protein, MESH: Heterozygote, MESH: Aged, 0303 health sciences, Mutation, education.field_of_study, MESH: Middle Aged, Homozygote, Liver Neoplasms, General Medicine, Middle Aged, Arabs, 3. Good health, MESH: Mutation, Missense, Morocco, 030220 oncology & carcinogenesis, Hereditary hemochromatosis, Female, MESH: Histocompatibility Antigens Class I / genetics, MESH: Alleles, MESH: Homozygote, Heterozygote, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, MESH: Carcinoma, Hepatocellular / epidemiology, Carcinoma, Hepatocellular, Population, Mutation, Missense, [SDV.CAN]Life Sciences [q-bio]/Cancer, Z mutation, 03 medical and health sciences, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, In patient, MESH: Genetic Predisposition to Disease / genetics, Allele, Hemochromatosis Protein, education, Allele frequency, Alleles, MESH: Prevalence, Aged, Retrospective Studies, 030304 developmental biology, HFE mutations, MESH: Humans, business.industry, Histocompatibility Antigens Class I, MESH: alpha 1-Antitrypsin / genetics, MESH: Carcinoma, Hepatocellular / genetics, Membrane Proteins, nutritional and metabolic diseases, MESH: Retrospective Studies, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, S mutation, MESH: Male, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, alpha 1-Antitrypsin, MESH: Liver Neoplasms / epidemiology, MESH: Morocco, MESH: Arabs, business, MESH: Female

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5658b90e28110c32f640b50cd367309cTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-02870414Test

المؤلفون: Meddeb-Garnaoui, A., Gritli, S, Garbouj, S, Ben Fadhel, M, El Kares, R., Mansour, M., Kaabi, B., Chouchane, L., Ben Salah, A., Dellagi, K.

المساهمون: Laboratoire d'Immunologie, Institut Pasteur de Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Case Western Reserve University Cleveland, Faculté de Médecine de Monastir Tunisie, Laboratoire d'Epidémiologie et d'Ecologie parasitaire, Institut Pasteur de Tunis, This work was supported by the Tunisian state secreteriete for scientific research and technology, and the Agency for International Development, through NIH/NIAID and the Middle East Regional Cooperation Program (NO1-AO-45183). Laboratories of Immunology and of Epidemiology and Ecology of Parasitic Diseases, Institut Pasteur de Tunis, were supported by UNDP/WB/WHO Special Program for Research and Training in Tropical Diseases (RSG/ID-890266) and by Agence Universitaire Francophone.

المصدر: ISSN: 0198-8859 ; Human Immunology ; https://riip.hal.science/pasteur-02027305Test ; Human Immunology, 2001, 62 (5), pp.509-517. ⟨10.1016/S0198-8859(01)00237-3⟩.

مصطلحات موضوعية: Leishmaniasis, DNA typing, HLA, candidate gene, tumor necrosis factor, genetic susceptibility, MHC genes, MESH: Animals, MESH: Child, Preschool, MESH: Infant, Newborn, MESH: Leishmania infantum, MESH: Leishmaniasis, Visceral/genetics, Visceral/immunology, MESH: Lymphotoxin-alpha/genetics, MESH: Mediterranean Region, MESH: Polymorphism, Genetic, MESH: Tumor Necrosis Factor-alpha/genetics, MESH: Genetic Predisposition to Disease/genetics, MESH: HLA-DQ Antigens/genetics, MESH: HLA-DQ beta-Chains, MESH: HLA-DR Antigens/genetics, MESH: HLA-DRB1 Chains, MESH: HSP70 Heat-Shock Proteins/genetics, MESH: Haplotypes, MESH: Humans, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/11334675; pasteur-02027305; https://riip.hal.science/pasteur-02027305Test; PUBMED: 11334675

الإتاحة: https://doi.org/10.1016/S0198-8859Test(01)00237-3
https://riip.hal.science/pasteur-02027305Test

المؤلفون: Barbouche, Mohamed Ridha, Sghiri, R, Mellouli, F., Boukhdir, Y, Dellagi, K., Bejaoui, M.

المساهمون: Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP), Centre National de Greffe de la Moëlle osseuse Tunis (CNGMO)

المصدر: ISSN: 0755-4982.

مصطلحات موضوعية: MESH: Aspergillosis/diagnosis, MESH: Aspergillosis/immunology, MESH: Granulomatous Disease, Chronic/genetics, Chronic/immunology, MESH: Humans, MESH: Immune Tolerance/immunology, MESH: Infant, MESH: Luminescent Measurements, MESH: Male, MESH: Neutrophils/immunology, MESH: Opportunistic Infections/diagnosis, MESH: Opportunistic Infections/immunology, MESH: Bacterial Infections/diagnosis, MESH: Respiratory Burst/immunology, MESH: Retrospective Studies, MESH: Bacterial Infections/immunology, MESH: Child, Preschool, MESH: Consanguinity, MESH: Female, MESH: Genetic Predisposition to Disease/genetics, Chronic/diagnosis, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/10605470; pasteur-01984596; https://riip.hal.science/pasteur-01984596Test; PUBMED: 10605470

الإتاحة: https://riip.hal.science/pasteur-01984596Test