المؤلفون: Ménoret, Séverine, Tesson, Laurent, Remy, Séverine, Gourain, Victor, Sérazin, Céline, Usal, Claire, Guiffes, Aude, Chenouard, Vanessa, Ouisse, Laure-Hélène, Gantier, Malika, Heslan, Jean-Marie, Fourgeux, Cynthia, Poschmann, Jeremie, Guillonneau, Carole, Anegon, Ignacio

المساهمون: Centre de Recherche en Transplantation et Immunologie - Center for Research in Transplantation and Translational Immunology (U1064 Inserm - CR2TI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Team 2 : Cell and gene engineering in tolerance, fertility and regenerative medicine (Team 2 - U1064 Inserm - CR2TI), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Structure fédérative de recherche François Bonamy (Nantes Univ - SFR François Bonamy), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université (Nantes Univ), Team 6 : Impact of acute inflammation on host pathogen interactions and lung homeostasis (Team 6 - U1064 Inserm - CR2TI), Center for Climate and Resilience Research Conception ((CR)2), Universidad de Concepción - University of Concepcion Chile, ANR-10-IBHU-0005,CESTI (TSI-IHU),Centre Européen des Sciences de la Transplantation et de l'Immunothérapie (TSI-IHU)(2010), ANR-11-LABX-0016,IGO,Immunothérapies Grand Ouest(2011)

المصدر: ISSN: 1741-7007.

مصطلحات موضوعية: CD4+ Treg, CD8+ Treg, Foxp3, Gene knockin, Genome editing, Immune tolerance, MESH: Animals, MESH: CD8-Positive T-Lymphocytes / metabolism, MESH: Forkhead Transcription Factors / genetics, MESH: Forkhead Transcription Factors / metabolism, MESH: Interleukin-2 / genetics, MESH: Interleukin-2 / metabolism, MESH: Rats, MESH: T-Lymphocytes, Regulatory / metabolism, MESH: Transforming Growth Factor beta / metabolism, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36635667; inserm-04062418; https://inserm.hal.science/inserm-04062418Test; https://inserm.hal.science/inserm-04062418/documentTest; https://inserm.hal.science/inserm-04062418/file/s12915-022-01502-0.pdfTest; PUBMED: 36635667; PUBMEDCENTRAL: PMC9837914

الإتاحة: https://doi.org/10.1186/s12915-022-01502-0Test
https://inserm.hal.science/inserm-04062418Test
https://inserm.hal.science/inserm-04062418/documentTest
https://inserm.hal.science/inserm-04062418/file/s12915-022-01502-0.pdfTest

المؤلفون: Sonia Ait-Younes, Mourad Belkhelfa, Chafia Touil-Boukoffa, Yvan de Launoit, Hassen Mahfouf, Hayet Rafa, Nadira Delhem, Hayat Ait-Kaci, Olivier Moralès, Sabah Hetit, Oussama Medjeber, Sarra Benkhelifa, Said Belhadef

المساهمون: Mécanismes de tumorigenèse et thérapies ciblées, Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), FGMGP/USTHB, Université d'Algérie, Hôpital Rouïba [Algerie], Le centre hospitalier universitaire (CHU) Mustapha Pacha [Alger], Centre Hospitalo-Universitaire de Béni-Messous, CHU Nafissa Hamoud [Hussein Dey], University of Sciences and Technology Houari Boumediene [Alger] (USTHB), Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Université de Lille, Droit et Santé, They also thank the national agency of research development in health (ATRSS) which supported their project (code project: 03/06/01/10/011). They have also received support from the SIRIC ONCO Lille., The authors would like to gratefully thank all the participants involved in this study as well as the technical staff of the department of oncology (Rouiba Hospital) and Anatomic Pathology Service (Mustapha Pacha Hospital). They greatly thank Meroua BOUCHEMAL, Arezki CHEKAOUI and Dr. Kahina TOURI (USTHB, Algiers, Algeria) for all help and support of this work. Special thanks are extended to Dr. Mohamed Boudjelal and Science Edit for the Developing World for editing the English Language of the paper., Université des Sciences et de la Technologie Houari Boumediene = University of Sciences and Technology Houari Boumediene [Alger] (USTHB), Institut de biologie de Lille - UMS 3702 (IBL), Université de Lille-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Inflammopharmacology
Inflammopharmacology, Springer Verlag, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
Inflammopharmacology, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩

مصطلحات موضوعية: 0301 basic medicine, Colorectal cancer, [SDV]Life Sciences [q-bio], medicine.medical_treatment, MESH: Up-Regulation/physiology, MESH: Down-Regulation/drug effects, MESH: Aged, 80 and over, 0302 clinical medicine, Host immune responses, MESH: Nitric Oxide/metabolism, MESH: Colorectal Neoplasms/metabolism, Pharmacology (medical), ComputingMilieux_MISCELLANEOUS, MESH: Aged, MESH: Middle Aged, Cetuximab, MESH: Nitric Oxide Synthase Type II/metabolism, FOXP3, 3. Good health, medicine.anatomical_structure, MESH: Cetuximab/therapeutic use, iNOS/NO system, MESH: Up-Regulation/drug effects, medicine.symptom, medicine.drug, Immunology, Inflammation, [SDV.CAN]Life Sciences [q-bio]/Cancer, MESH: Immunologic Factors/metabolism, Peripheral blood mononuclear cell, Immunomodulation, 03 medical and health sciences, Immune system, MESH: Down-Regulation/physiology, medicine, MESH: Biomarkers, Tumor/metabolism, Cetuximab and chemotherapy, Colorectal Cancer, Pharmacology, Chemotherapy, MESH: Humans, business.industry, MESH: Adult, medicine.disease, MESH: Male, 030104 developmental biology, Cancer research, MESH: Colorectal Neoplasms/drug therapy, business, MESH: Female, Memory T cell, MESH: T-Lymphocytes, Regulatory/drug effects, 030217 neurology & neurosurgery, MESH: Forkhead Transcription Factors/metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c14e2c54400f0d81e84b20996df275Test
https://hal.archives-ouvertes.fr/hal-03059991Test

المؤلفون: Benkhelifa, Sarra, Rafa, Hayet, Belhadef, Said, Ait-Kaci, Hayat, Medjeber, Oussama, Belkhelfa, Mourad, Hetit, Sabah, Ait-Younes, Sonia, de Launoit, Yvan, Morales, Olivier, Mahfouf, Hassen, Delhem, Nadira, Touil-Boukoffa, Chafia

المساهمون: Université des Sciences et de la Technologie Houari Boumediene = University of Sciences and Technology Houari Boumediene Alger (USTHB), Institut de biologie de Lille - UMS 3702 (IBL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Hôpital Rouïba Algerie, Le centre hospitalier universitaire (CHU) Mustapha Pacha Alger, Centre Hospitalo-Universitaire de Béni-Messous, CHU Nafissa Hamoud Hussein Dey, Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), They also thank the national agency of research development in health (ATRSS) which supported their project (code project: 03/06/01/10/011). They have also received support from the SIRIC ONCO Lille., The authors would like to gratefully thank all the participants involved in this study as well as the technical staff of the department of oncology (Rouiba Hospital) and Anatomic Pathology Service (Mustapha Pacha Hospital). They greatly thank Meroua BOUCHEMAL, Arezki CHEKAOUI and Dr. Kahina TOURI (USTHB, Algiers, Algeria) for all help and support of this work. Special thanks are extended to Dr. Mohamed Boudjelal and Science Edit for the Developing World for editing the English Language of the paper.

المصدر: ISSN: 0925-4692.

مصطلحات موضوعية: Colorectal Cancer, Cetuximab and chemotherapy, iNOS/NO system, Host immune responses, Immunomodulation, MESH: Adult, MESH: Aged, MESH: Forkhead Transcription Factors/metabolism, MESH: Humans, MESH: Immunologic Factors/metabolism, MESH: Male, MESH: Middle Aged, MESH: Nitric Oxide/metabolism, MESH: Nitric Oxide Synthase Type II/metabolism, MESH: T-Lymphocytes, Regulatory/drug effects, MESH: Up-Regulation/drug effects, MESH: Up-Regulation/physiology, 80 and over, MESH: Biomarkers, Tumor/metabolism, MESH: Cetuximab/therapeutic use, MESH: Colorectal Neoplasms/drug therapy, MESH: Colorectal Neoplasms/metabolism, MESH: Down-Regulation/drug effects, MESH: Down-Regulation/physiology, MESH: Female, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30680650; hal-02391591; https://hal.science/hal-02391591Test; PUBMED: 30680650

الإتاحة: https://doi.org/10.1007/s10787-019-00566-9Test
https://hal.science/hal-02391591Test

المؤلفون: Olivier Moralès, Nathalie Martin, Dhafer Mrizak, Yvan de Launoit, Joël Guigay, Clément Barjon, Anne-Sophie Jimenez-Pailhes, Toshiro Niki, Philippe Busson, Nadira Delhem, Véronique Pancré, Rami Mustapha

المساهمون: Institut de biologie de Lille - IBL (IBLI), Université de Lille, Sciences et Technologies-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS)-Université de Lille, Droit et Santé, Institut de biologie de Lille - UMS 3702 (IBL), Université de Lille-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre National de la Recherche Scientifique (CNRS), Signalisation, noyaux et innovations en cancérologie (UMR8126), Université Paris-Sud - Paris 11 (UP11)-Institut Gustave Roussy (IGR)-Centre National de la Recherche Scientifique (CNRS), Kagawa University [Japan], GalPharma Co., Ltd. [Kagawa, Japan], Département de cancérologie cervico-faciale [Gustave Roussy] (CCF), Institut Gustave Roussy (IGR), This work received the financial support from the Association de Recherche contre le Cancer, the Fondation de Recherche Médicale, OSEO, and the Nord-Pas-de Calais Region. This work was also supported by SIRIC ONCOLille and INCa-DHOS exoplasma 2010., We thank Han Wong and Niels Wambre for their technical assistance and Jean-Pierre Decavel, Thierry Chassat, and Anthony Mouray for their technical support, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille, Droit et Santé-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut Gustave Roussy (IGR)-Université Paris-Sud - Paris 11 (UP11)

المصدر: JNCI: Journal of the National Cancer Institute
JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), 2015, 107 (1), pp.363. ⟨10.1093/jnci/dju363⟩
JNCI: Journal of the National Cancer Institute, 2015, 107 (1), pp.363. ⟨10.1093/jnci/dju363⟩

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, MESH: T-Lymphocytes/metabolism, MESH: Exosomes/immunology, Cancer Research, [SDV]Life Sciences [q-bio], neoplasms, MESH: Flow Cytometry, Mice, SCID, MESH: Forkhead Transcription Factors/metabolism, Stem cell marker, T-Lymphocytes, Regulatory, antigens/cd25, Mice, 0302 clinical medicine, Medicine, MESH: Animals, IL-2 receptor, MESH: Mice, SCID, 0303 health sciences, MESH: Real-Time Polymerase Chain Reaction, MESH: Exosomes/metabolism, MESH: Nasopharyngeal Neoplasms/immunology, Peripheral tolerance, FOXP3, Forkhead Transcription Factors, hemic and immune systems, MESH: Gene Expression Regulation, Neoplastic, Flow Cytometry, 3. Good health, Interleukin-10, Gene Expression Regulation, Neoplastic, Interleukin 10, MESH: Nasopharyngeal Neoplasms/metabolism, MESH: Transforming Growth Factor beta1/immunology, Oncology, 030220 oncology & carcinogenesis, Heterografts, regulatory, MESH: Interleukin-10/immunology, MESH: Cell Line, Tumor, phenotype, Blotting, Western, chemical and pharmacologic phenomena, exosomes, Real-Time Polymerase Chain Reaction, MESH: Chemokine CCL20/metabolism, GZMB, Transforming Growth Factor beta1, MESH: CD4-Positive T-Lymphocytes/immunology, 03 medical and health sciences, Immune system, Cell Line, Tumor, MESH: T-Lymphocytes/immunology, MESH: Cell Proliferation, otorhinolaryngologic diseases, Animals, Humans, MESH: Blotting, Western, MESH: T-Lymphocytes, Regulatory/metabolism, t-lymphocytes, MESH: Mice, 030304 developmental biology, Cell Proliferation, Chemokine CCL20, MESH: Humans, business.industry, MESH: CD4-Positive T-Lymphocytes/metabolism, MESH: Interleukin-2 Receptor alpha Subunit/metabolism, Carcinoma, MESH: T-Lymphocytes, Regulatory/immunology, Interleukin-2 Receptor alpha Subunit, Nasopharyngeal Neoplasms, medicine.disease, MESH: Carcinoma/immunology, stomatognathic diseases, Nasopharyngeal carcinoma, Immunology, MESH: Carcinoma/metabolism, Cancer research, MESH: Heterografts, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b26db81f55015844852428f12ebb866Test
https://hal.archives-ouvertes.fr/hal-02395739Test