المؤلفون: Adoue, Véronique, Joffre, Olivier

المساهمون: Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Région Occitanie NVEQ 2014 - Contrat : 14051291, FRM - Contrat : AJE201212, ANR-19-CE15-0022,ImmuneTrans,Rôle des éléments transposables dans la réponse des cellules immunitaires aux signaux développementaux et environnementaux(2019), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014)

المصدر: ISSN: 0767-0974.

مصطلحات موضوعية: MESH: Animals, MESH: CD4-Positive T-Lymphocytes / physiology, MESH: Cell Lineage / genetics, MESH: Cell Lineage / immunology, MESH: Dendritic Cells / immunology, MESH: Dendritic Cells / physiology, MESH: Endogenous Retroviruses / genetics, MESH: Endogenous Retroviruses / immunology, MESH: Endogenous Retroviruses / physiology, MESH: Epigenesis, Genetic / physiology, MESH: Humans, MESH: Immune System Phenomena / physiology, MESH: Lymphocyte Activation / physiology, MESH: T-Lymphocyte Subsets / immunology, MESH: T-Lymphocyte Subsets / physiology, MESH: Cell Differentiation / genetics, MESH: Cell Differentiation / immunology, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32228844; hal-03015778; https://hal.science/hal-03015778Test; https://hal.science/hal-03015778/documentTest; https://hal.science/hal-03015778/file/msc190228.pdfTest; PUBMED: 32228844

الإتاحة: https://doi.org/10.1051/medsci/2020022Test
https://hal.science/hal-03015778Test
https://hal.science/hal-03015778/documentTest
https://hal.science/hal-03015778/file/msc190228.pdfTest

المؤلفون: Gehrmann, Ulf, Burbage, Marianne, Zueva, Elina, Goudot, Christel, Esnault, Cyril, Ye, Mengliang, Carpier, Jean-Marie, Burgdorf, Nina, Hoyler, Thomas, Suarez, Guadalupe, Joannas, Leonel, Heurtebise-Chrétien, Sandrine, Durand, Sylvère, Panes, Rébecca, Bellemare-Pelletier, Angélique, Sáez, Pablo, J, Aprahamian, Fanny, Lefevre, Deborah, Adoue, Véronique, El Aabidine, Amal Zine, Muhammad, Maqbool, Hivroz, Claire, Joffre, Olivier, Cammas, Florence, Marie, Kroemer, Guido, Gagnon, Etienne, Andrau, Jean-Christophe, Amigorena, Sebastian

المساهمون: Immunité et cancer (U932), Institut Curie Paris -Institut National de la Santé et de la Recherche Médicale (INSERM), AstraZeneca, Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Métabolisme, Cancer et Immunité (CRC - UMR_S 1138), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Université de Montréal (UdeM), Institut de Recherche en Immunologie et en Cancérologie UdeM-Montréal (IRIC), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Karolinska University Hospital Stockholm, ANR-10-BLAN-1326,chromaTin,Dynamique de la chromatine au cours de l'activation des lympohocytes T: role de HP1(2010), ANR-11-LABX-0043,DCBIOL,Biologie des cellules dendritiques(2011), ANR-10-IDEX-0001,PSL,Paris Sciences et Lettres(2010), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014), ANR-10-INBS-0009,France Génomique,Organisation et montée en puissance d'une Infrastructure Nationale de Génomique(2010), ANR-11-LABX-0038,CelTisPhyBio,Des cellules aux tissus: au croisement de la Physique et de la Biologie(2011), ANR-16-CE18-0023,Healskin,Matrices pour la régénération et la cicatrisation cutanée(2016), ANR-10-EQPX-0003,ICGex,Equipement de biologie intégrative du cancer pour une médecine personnalisée(2010), ANR-11-LABX-0044,DEEP,Développement, Epigénèse, Epigénétique et potentiel de vie(2011), European Project: 340046,EC:FP7:ERC,ERC-2013-ADG,DCBIOX(2014)

المصدر: ISSN: 0027-8424.

مصطلحات موضوعية: T cells, TRIM28, autoimmunity, epigenetics, immunology, MESH: Animals, MESH: Autoimmunity / physiology, MESH: Cell Differentiation / physiology, MESH: Cell Plasticity / physiology, MESH: Cellular Reprogramming / genetics, MESH: Cellular Reprogramming / physiology, MESH: Chromobox Protein Homolog 5, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: Colon / pathology, MESH: Cytokines / metabolism, MESH: DNA-Binding Proteins / genetics, MESH: DNA-Binding Proteins / metabolism, MESH: Epigenesis, Genetic / physiology, MESH: Gene Expression Regulation, MESH: CD4-Positive T-Lymphocytes / metabolism, MESH: Cell Differentiation / genetics, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31776254; info:eu-repo/grantAgreement/EC/FP7/340046/EU/Phagosome functions and antigen cross presentation in primary dendritic cells./DCBIOX; hal-02369616; https://hal.science/hal-02369616Test; https://hal.science/hal-02369616/documentTest; https://hal.science/hal-02369616/file/pnas.201901639.pdfTest; PUBMED: 31776254; PUBMEDCENTRAL: PMC6925996

الإتاحة: https://doi.org/10.1073/pnas.1901639116Test
https://hal.science/hal-02369616Test
https://hal.science/hal-02369616/documentTest
https://hal.science/hal-02369616/file/pnas.201901639.pdfTest

المؤلفون: Padhi, Avinash, Srivastava, Ankit, Ramesh, Abarajitha, Ehrström, Marcus, Simon, Michel, Sonkoly, Enikö, Eidsmo, Liv, Bergman, Peter, Lysell, Josefin

المساهمون: Karolinska Institutet Stockholm, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stanford University, Uppsala University, Karolinska University Hospital Stockholm, Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Diagnostiskt Centrum Hud

المصدر: ISSN: 0022-202X.

مصطلحات موضوعية: MESH: Acitretin / pharmacology, MESH: Acitretin / therapeutic use, MESH: Dermatitis, Atopic / pathology, MESH: Down-Regulation, MESH: Epidermis / drug effects, MESH: Epidermis / enzymology, MESH: Epidermis / pathology, MESH: Filaggrin Proteins / metabolism, MESH: Biopsy, MESH: Cell Differentiation / drug effects, MESH: Cell Differentiation / genetics, MESH: Cell Line, MESH: Citrullination / drug effects, MESH: Citrullination / genetics, Atopic / drug therapy, Atopic / genetics, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34352263; hal-03652374; https://hal.science/hal-03652374Test; PUBMED: 34352263

الإتاحة: https://doi.org/10.1016/j.jid.2021.07.155Test
https://hal.science/hal-03652374Test

المؤلفون: Rotureau, Brice, Ooi, Cher-Pheng, Huet, Diego, Perrot, Sylvie, Bastin, Philippe

المساهمون: Biologie Cellulaire des Trypanosomes, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), ANR-08-MIEN-0027,SENSOTRYPA,Rôles sensoriels du flagelle au cours du cycle parasitaire du trypanosome africain(2008), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010)

المصدر: ISSN: 1462-5814.

مصطلحات موضوعية: Trypanosoma brucei, flagellum, DNAI1, motility, tsetse fly, vector, infection, MESH: Animals, MESH: Cell Differentiation/genetics, MESH: RNA, Small Interfering, MESH: Trypanosoma brucei brucei/growth & development, MESH: Trypanosomiasis, African/parasitology, MESH: Tsetse Flies/parasitology, MESH: Digestive System/metabolism, MESH: Dyneins/genetics, MESH: Gastrointestinal Tract/parasitology, MESH: Locomotion/genetics, MESH: Male, MESH: RNA Interference, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/24134537; pasteur-01301209; https://pasteur.hal.science/pasteur-01301209Test; https://pasteur.hal.science/pasteur-01301209/documentTest; https://pasteur.hal.science/pasteur-01301209/file/Forward_motility.pdfTest; PUBMED: 24134537

الإتاحة: https://doi.org/10.1111/cmi.12230Test
https://pasteur.hal.science/pasteur-01301209Test
https://pasteur.hal.science/pasteur-01301209/documentTest
https://pasteur.hal.science/pasteur-01301209/file/Forward_motility.pdfTest

المؤلفون: Véronique Adoue, Olivier Joffre

المساهمون: Adoue, Veronique, Rôle des éléments transposables dans la réponse des cellules immunitaires aux signaux développementaux et environnementaux - - ImmuneTrans2019 - ANR-19-CE15-0022 - AAPG2019 - VALID, Appel à projets générique - Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome - - EpiTreg2014 - ANR-14-CE14-0021 - Appel à projets générique - VALID, Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Région Occitanie NVEQ 2014 - Contrat : 14051291, FRM - Contrat : AJE201212, ANR-19-CE15-0022,ImmuneTrans,Rôle des éléments transposables dans la réponse des cellules immunitaires aux signaux développementaux et environnementaux(2019), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014), ANR-14-CE14-0021,EpiTreg ,EpiTreg

المصدر: médecine/sciences
médecine/sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
médecine/sciences, EDP Sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩

مصطلحات موضوعية: MESH: Dendritic Cells / physiology, T cell, Gene regulatory network, Endogenous retrovirus, Priming (immunology), MESH: Endogenous Retroviruses / immunology, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Immune system, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, MESH: Animals, Epigenetics, MESH: Lymphocyte Activation / physiology, Gene, MESH: Cell Lineage / genetics, MESH: CD4-Positive T-Lymphocytes / physiology, 030304 developmental biology, 0303 health sciences, MESH: Humans, MESH: T-Lymphocyte Subsets / physiology, MESH: Immune System Phenomena / physiology, General Medicine, MESH: Cell Differentiation / genetics, 3. Good health, Chromatin, Cell biology, medicine.anatomical_structure, [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology, 030220 oncology & carcinogenesis, [SDV.IMM.IA] Life Sciences [q-bio]/Immunology/Adaptive immunology, MESH: T-Lymphocyte Subsets / immunology, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], MESH: Epigenesis, Genetic / physiology, MESH: Dendritic Cells / immunology, MESH: Cell Differentiation / immunology, MESH: Cell Lineage / immunology, MESH: Endogenous Retroviruses / genetics, MESH: Endogenous Retroviruses / physiology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d8bbf56b7f22d0ec282cc76e4db22fTest
https://doi.org/10.1051/medsci/2020022Test

المؤلفون: Giordani, Lorenzo, He, Gary, Negroni, Elisa, Sakai, Hiroshi, Law, Justin Y.C., Siu, M Mona, Wan, Raymond, Corneau, Aurélien, Tajbakhsh, Shahragim, Cheung, Tom, Le Grand, Fabien

المساهمون: Centre de recherche en Myologie – U974 SU-INSERM, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Hong Kong University of Science and Technology (HKUST), Cellules Souches et Développement / Stem Cells and Development, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Max Planck Institute for Heart and Lung Research (MPI-HLR), Max-Planck-Gesellschaft, Plateforme Cytométrie Pitié-Salpêtrière (LUMIC-CYPS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Unité Mixte de Service d'Imagerie et de Cytométrie CHU Saint-Antoine (UMS LUMIC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), This study was supported by ANR/RGC (Agence Nationale pour la Recherche/Research Grant Council) grant ANR-14-CE11-0026/A-HKUST604/14 (to F.L.G. and T.C.), an Association Française contre les Myopathies/AFM Telethon grant to F.L.G., the Hong Kong Research Grant Council (research grants C6015-14G, C6003-14G, C6009-15G, AoE/M-604/16, and T13-607/12R to T.H.C.), and the Croucher Innovation Award (T.H.C.)., We thank Catherine Blanc (CyPS Facility) for technical support. We thank Bruno Cadot, Christophe Combadière, Glenda Comai, and Vincent Mouly for providing transgenic mice. We thank Gilian Butler-Browne, Florian Bentzinger, David Sassoon, Rémi Mounier, and Capucine Trollet for commenting on the manuscript.

المصدر: ISSN: 1097-2765.

مصطلحات موضوعية: CyTOF, satellite cells, single-cell RNA-seq, skeletal muscle stem cells, MESH: Animals, MESH: Cell Differentiation/genetics, MESH: Satellite Cells, Skeletal Muscle/metabolism, MESH: Single-Cell Analysis, MESH: Stem Cells/cytology, MESH: Stem Cells/metabolism, MESH: Cell Lineage/genetics, MESH: Mice, MESH: Muscle Development/genetics, MESH: Muscle Fibers, Skeletal/cytology, Skeletal/metabolism, MESH: Myoblasts/cytology, MESH: Myoblasts/metabolism, Skeletal Muscle/cytology, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30922843; hal-02376541; https://hal.science/hal-02376541Test; BIORXIV: 304683; PUBMED: 30922843

الإتاحة: https://doi.org/10.1016/j.molcel.2019.02.026Test
https://hal.science/hal-02376541Test

المؤلفون: Marianne Burbage, Pablo J. Sáez, Deborah Lefevre, Thomas Hoyler, Amal Zine El Aabidine, Rébecca Panes, Guadalupe Suarez, Christel Goudot, Sebastian Amigorena, Jean-Marie Carpier, Mengliang Ye, Fanny Aprahamian, Claire Hivroz, Florence Cammas, Olivier Joffre, Véronique Adoue, Elina Zueva, Jean-Christophe Andrau, Angelique Bellemare-Pelletier, Sylvère Durand, Leonel Joannas, Etienne Gagnon, Maqbool Muhammad Ahmad, Guido Kroemer, Cyril Esnault, Ulf Gehrmann, Sandrine Heurtebise-Chrétien, Nina Burgdorf

المساهمون: Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Immunité et cancer (U932), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), AstraZeneca, Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Métabolisme, Cancer et Immunité (CRC - UMR_S 1138), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Université de Montréal (UdeM), Institut de Recherche en Immunologie et en Cancérologie [UdeM-Montréal] (IRIC), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Karolinska University Hospital [Stockholm], ANR-10-BLAN-1326,chromaTin,Dynamique de la chromatine au cours de l'activation des lympohocytes T: role de HP1(2010), ANR-11-LABX-0043,DCBIOL,Biologie des cellules dendritiques(2011), ANR-10-IDEX-0001,PSL,Paris Sciences et Lettres(2010), ANR-14-CE14-0021,EpiTreg,Régulation épigénétique du développement et de l'activité des lymphocytes T (régulateurs) par HP1 et son interactome(2014), ANR-10-INBS-0009,France-Génomique,Organisation et montée en puissance d'une Infrastructure Nationale de Génomique(2010), ANR-11-LABX-0038,CelTisPhyBio,Des cellules aux tissus: au croisement de la Physique et de la Biologie(2011), ANR-16-CE18-0023,Healskin,Matrices pour la régénération et la cicatrisation cutanée(2016), ANR-10-EQPX-0003,ICGex,Equipement de biologie intégrative du cancer pour une médecine personnalisée(2010), ANR-11-LABX-0044,DEEP,Développement, Epigénèse, Epigénétique et potentiel de vie(2011), European Project: 340046,EC:FP7:ERC,ERC-2013-ADG,DCBIOX(2014)

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Chromosomal Proteins, Non-Histone, MESH: Cellular Reprogramming / genetics, T-Lymphocytes, MESH: Cellular Reprogramming / physiology, [SDV]Life Sciences [q-bio], Cell Plasticity, MESH: Chromobox Protein Homolog 5, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Tripartite Motif-Containing Protein 28, T-Lymphocytes, Regulatory, [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity, Epigenesis, Genetic, Histones, immunology, Mice, Phosphatidylinositol 3-Kinases, Immunology and Inflammation, 0302 clinical medicine, MESH: Animals, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, 0303 health sciences, Multidisciplinary, Effector, autoimmunity, Cell Differentiation, MESH: DNA-Binding Proteins / metabolism, Biological Sciences, MESH: Cell Differentiation / physiology, Cellular Reprogramming, MESH: Gene Expression Regulation, MESH: Cell Differentiation / genetics, Chromatin, Cell biology, DNA-Binding Proteins, medicine.anatomical_structure, PNAS Plus, Regulatory sequence, 030220 oncology & carcinogenesis, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: Epigenesis, Genetic / physiology, MESH: Cell Plasticity / physiology, Colon, T cell, Receptors, Antigen, T-Cell, T cells, Biology, 03 medical and health sciences, MESH: CD4-Positive T-Lymphocytes / metabolism, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Animals, Gene silencing, Gene Silencing, Epigenetics, 030304 developmental biology, Histone binding, MESH: DNA-Binding Proteins / genetics, epigenetics, TRIM28, MESH: Cytokines / metabolism, T-cell receptor, Gene Expression Regulation, Chromobox Protein Homolog 5, MESH: Autoimmunity / physiology, MESH: Colon / pathology, Transcriptome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdc87a7d673a9a3997e6fdd23ac6a75Test
https://hal.archives-ouvertes.fr/hal-02369616/documentTest

المؤلفون: Gary J. He, Aurélien Corneau, Tom H. Cheung, Elisa Negroni, Hiroshi Sakai, M. Mona Siu, Raymond Wan, Shahragim Tajbakhsh, Lorenzo Giordani, Justin Y. C. Law, Fabien Le Grand

المساهمون: Centre de recherche en Myologie – U974 SU-INSERM, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Hong Kong University of Science and Technology (HKUST), Cellules Souches et Développement / Stem Cells and Development, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Max Planck Institute for Heart and Lung Research (MPI-HLR), Max-Planck-Gesellschaft, Plateforme Cytométrie Pitié-Salpêtrière (LUMIC-CYPS), Unité Mixte de Service d'Imagerie et de Cytométrie [CHU Saint-Antoine] (UMS LUMIC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), This study was supported by ANR/RGC (Agence Nationale pour la Recherche/Research Grant Council) grant ANR-14-CE11-0026/A-HKUST604/14 (to F.L.G. and T.C.), an Association Française contre les Myopathies/AFM Telethon grant to F.L.G., the Hong Kong Research Grant Council (research grants C6015-14G, C6003-14G, C6009-15G, AoE/M-604/16, and T13-607/12R to T.H.C.), and the Croucher Innovation Award (T.H.C.)., We thank Catherine Blanc (CyPS Facility) for technical support. We thank Bruno Cadot, Christophe Combadière, Glenda Comai, and Vincent Mouly for providing transgenic mice. We thank Gilian Butler-Browne, Florian Bentzinger, David Sassoon, Rémi Mounier, and Capucine Trollet for commenting on the manuscript., Centre de Recherche en Myologie, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Unité Mixte de Service d'Imagerie et de Cytométrie [CHU Saint-Antoine] (UMS LUMIC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)

المصدر: Molecular Cell
Molecular Cell, Elsevier, 2019, 74 (3), pp.609-621.e6. ⟨10.1016/j.molcel.2019.02.026⟩
Molecular Cell, 2019, 74 (3), pp.609-621.e6. ⟨10.1016/j.molcel.2019.02.026⟩

مصطلحات موضوعية: MESH: Muscle Fibers, Skeletal/metabolism, Cell type, MESH: Muscle Fibers, Skeletal/cytology, Satellite Cells, Skeletal Muscle, [SDV]Life Sciences [q-bio], Cell, Muscle Fibers, Skeletal, skeletal muscle stem cells, Biology, Muscle Development, Myoblasts, 03 medical and health sciences, Mice, 0302 clinical medicine, MESH: Stem Cells/metabolism, medicine, Compartment (development), MESH: Myoblasts/metabolism, MESH: Satellite Cells, Skeletal Muscle/metabolism, Animals, MESH: Animals, Cell Lineage, MESH: Satellite Cells, Skeletal Muscle/cytology, MESH: Cell Lineage/genetics, Molecular Biology, MESH: Mice, 030304 developmental biology, satellite cells, 0303 health sciences, single-cell RNA-seq, Regeneration (biology), MESH: Cell Differentiation/genetics, Stem Cells, Mesenchymal stem cell, Scleraxis, MESH: Myoblasts/cytology, Skeletal muscle, Cell Differentiation, Cell Biology, Cell biology, Transplantation, MESH: Stem Cells/cytology, medicine.anatomical_structure, MESH: Muscle Development/genetics, CyTOF, Single-Cell Analysis, 030217 neurology & neurosurgery, MESH: Single-Cell Analysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b39aea4fb8ca4e7185adbe7f87a1f19Test
https://pubmed.ncbi.nlm.nih.gov/30922843Test

المؤلفون: Beziat, Vivien, Li, Juan, Lin, Jian-Xin, Ma, Cindy, Li, Peng, Bousfiha, Aziz, Pellier, Isabelle, Zoghi, Samaneh, Baris, Safa, Keles, Sevgi, Gray, Paul, Du, Ning, Wang, Yi, Zerbib, Yoann, Levy, Romain, Leclercq, Thibaut, About, Frédégonde, Lim, Ai Ing, Rao, Geetha, Payne, Kathryn, Pelham, Simon, Avery, Danielle, Deenick, Elissa, Pillay, Bethany, Chou, Janet, Guery, Romain, Belkadi, Aziz, Guerin, Antoine, Migaud, Melanie, Rattina, Vimel, Ailal, Fatima, Benhsaien, Ibtihal, Bouaziz, Matthieu, Habib, Tanwir, Chaussabel, Damien, Marr, Nico, El-Benna, Jamel, Grimbacher, Bodo, Wargon, Orli, Bustamante, Jacinta, Boisson, Bertrand, Müller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Chandesris, Marie-Olivia, Titeux, Matthias, Fraitag, Sylvie, Alyanakian, Marie-Alexandra, Leruez-Ville, Marianne, Picard, Capucine, Meyts, Isabelle, Di Santo, James, P, Hovnanian, Alain, Somer, Ayper, Ozen, Ahmet, Rezaei, Nima, Chatila, Talal, Abel, Laurent, Leonard, Warren, Tangye, Stuart, G., Puel, Anne, Casanova, Jean-Laurent

المساهمون: Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rockefeller University New York, National Institutes of Health Bethesda, MD, USA (NIH), Garvan Institute of medical research, University of New South Wales Sydney (UNSW), CHU Ibn Rochd Casablanca, Université Hassan II Casablanca (UH2MC), Service d'Immuno-Hémato-Oncologie Pédiatrique, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Shahid Beheshti University of Medical Sciences Tehran (SBUMS), Universal Scientific Education and Research Network (USERN), Marmara University Kadıköy - İstanbul, Necmettin Erbakan University Konya, Turquie, Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Harvard Medical School Boston (HMS), Boston Children's Hospital, Centre d'infectiologie Necker-Pasteur CHU Necker, Institut Pasteur Paris (IP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sidra Medicine Doha, Qatar, Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Universitäts Klinikum Freiburg = University Medical Center Freiburg (Uniklinik), Sydney Children's hospital, Centre de Référence Déficits Immunitaires Héréditaires (CEREDIH), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Friedrich-Alexander Universität Erlangen-Nürnberg = University of Erlangen-Nuremberg (FAU), Genetic skin diseases : from disease mechanism to therapies (Equipe Inserm U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de pathologie CHU Necker, Service d'immuno-hématologie pédiatrique CHU Necker, Laboratoire de Virologie CHU Necker, Université Paris Descartes - Paris 5 (UPD5), Centre d'étude des Déficits Immunitaires, University Hospitals Leuven Leuven, Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), Hôpital Necker - Enfants Malades AP-HP, Istanbul University, Research Center for Immunodeficiencies Tehran, Iran, Tehran University of Medical Sciences (TUMS), University of New South Wales Canberra Campus (UNSW), Howard Hughes Medical Institute New York (HHMI), Howard Hughes Medical Institute (HHMI)-New York University School of Medicine, NYU System (NYU)-NYU System (NYU)-Rockefeller University New York -Columbia University Irving Medical Center (CUIMC), This work was supported by grants from INSERM, Paris Descartes University, Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (ANR-10-LABX-62-IBEID), the Jeffrey Modell Foundation Translational Research Program, the French National Research Agency (ANR, grant nos. GENCMCD-ANR-11-BSV3–005-01, HGDIFD-ANR-14-CE15-0006-01, NKIR-ANR-13-PDOC-0025-01, and EURO-CMC-ANR-14-RARE-0005-02), and grants awarded under the “Investissement d’avenir” program (grant no. ANR-10-IAHU-01), the National Institute of Allergy and Infectious Diseases of the NIH (grant nos. U01AI109697 and R01AI127564), the Rockefeller University, the Howard Hughes Medical Institute, the St. Giles Foundation, the Institut Pasteur, and FP7, under grant agreements 305578 (PathCO) and 317057 (HOMIN). We thank the Centre de Recherche Translationnelle (Institut Pasteur) for technical assistance. V.B. is supported by the ANR (grant no. NKIR-ANR-13-PDOC-0025-01). R.L. is supported by the INSERM Ph.D. program (Poste d’Accueil INSERM), a Fulbright grant (Franco-American commission), and a Philippe Foundation scholarship. Y.Z. received the “médaille d’or du Centre Hospitalier Universitaire d’Amiens.” Y.W. is supported by the French National Agency for Research on AIDS and Viral Hepatitis (ANRS, grant no. 13318). F. About holds a fellowship from Fondation pour la Recherche Médicale (FRM, grant no. FDM20140630671). A.G. is supported by an IFNGPHOX grant (no. ANR13-ISV3-0001-01) from ANR. B.G. was funded by BMBF (German Federal Ministry of Education and Research) grants 01E01303 and 01ZX1306F. I.M. is supported by a klinische onderzoeks-en opleidingsraad (clinical research council) grant from UZ Leuven, a klinisch onderzoeksfonds (clinical research fund) grant from KU Leuven, and an International Mobility Grant from Fonds voor Wetenschappelijk Onderzoek (fund for scientific research) Vlaanderen. C.S.M., E.K.D., and S.G.T. are supported by grants and fellowships from the National Health and Medical Research Council of Australia. C.S.M., P.G., E.K.D., and S.G.T. are members of CIRCA (Clinical Immunogenomics Research Consortia Australia), which is funded by the Office of Health and Medical Research of the NSW Government, the Jeffrey Modell Foundation, and the John Cook Brown Foundation. A.I.L. is a scholar of the Pasteur-Paris University International Ph.D. program and is supported by a Ph.D. International Training Network grant from the European Union’s Seventh Framework Program under grant agreement no. 317057 (HOMIN). T.A.C. was supported by a grant from the National Institute of Allergy and Infectious Diseases of the NIH (5R01AI065617). S.K. was supported by a grant from the Scientific and Technological Research Council of Turkey (1059B191300622). J.-X.L., P.L., N.D., and W.J.L. were supported by the Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH. A.P. was supported by an AP-HP interface contract., We thank the patients and their families for participating in this study. We thank J. E. Darnell and C. Mertens for advice and for providing reagents. We thank the members of the laboratory, especially F. Jabot-Hanin and V. Pedergnana, for their valuable input on linkage analysis, L. Amar, Y. Nemirovskaya, D. Papandrea, E. Anderson, M. Woollett, C. Desvallées, C. Patissier, and M. Corrias for administrative assistance, E. Jouanguy and Y. Itan for helpful discussions, S. Boucherit for clinical data collection, S. Jacques and the Cochin genomics platform for microarray experiments, and N. Goudin and R. Desveaux of the Necker Institute Imaging Facility.

المصدر: ISSN: 2470-9468 ; Science Immunology ; https://hal.science/hal-02392068Test ; Science Immunology, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩.

مصطلحات موضوعية: MESH: Adolescent, MESH: Adult, MESH: Job Syndrome/genetics, MESH: Job Syndrome/immunology, MESH: Cell Differentiation/genetics, MESH: Loss of Function Mutation, MESH: Lymphocyte Count, MESH: Male, MESH: Middle Aged, MESH: Pedigree, MESH: Promoter Regions, Genetic/genetics, MESH: RNA, Messenger/metabolism, MESH: Gene Expression Regulation/immunology, MESH: STAT3 Transcription Factor/genetics, MESH: STAT3 Transcription Factor/immunology, MESH: STAT3 Transcription Factor/metabolism, MESH: Cell Differentiation/immunology, MESH: Th17 Cells/immunology, MESH: Th17 Cells/metabolism, MESH: Th2 Cells/immunology, MESH: Th2 Cells/metabolism, MESH: Transcription Factors/genetics, MESH: Transcription Factors/immunology, MESH: Genes, Recessive/genetics, MESH: Transcription Factors/metabolism, MESH: Transcription, Genetic/immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29907691; hal-02392068; https://hal.science/hal-02392068Test; PUBMED: 29907691; PUBMEDCENTRAL: PMC6141026

الإتاحة: https://doi.org/10.1126/sciimmunol.aat4956Test
https://hal.science/hal-02392068Test

المؤلفون: Warren J. Leonard, Nima Rezaei, Kathryn Payne, Isabelle Meyts, Laurent Abel, Cindy S. Ma, Marianne Leruez-Ville, Janet Chou, Alain Hovnanian, Jian-Xin Lin, Simon J. Pelham, Danielle T. Avery, Matthieu Bouaziz, Bethany Pillay, Tanwir Habib, Anne Puel, Sevgi Keles, Juan Li, Isabelle Pellier, Jamel El-Benna, Bernhard Fleckenstein, Ahmet Ozen, Vivien Béziat, Ingrid Müller-Fleckenstein, Damien Chaussabel, Samaneh Zoghi, Yi Wang, Paul Gray, Matthias Titeux, Yoann Zerbib, Talal A. Chatila, Marie-Alexandra Alyanakian, Capucine Picard, Orli Wargon, Ayper Somer, Marie-Olivia Chandesris, Thibaut Leclercq, Ibtihal Benhsaien, Aziz Belkadi, Jean-Laurent Casanova, Romain Lévy, Peng Li, Geetha Rao, Ai Ing Lim, James P. Di Santo, Nico Marr, Sylvie Fraitag, Frédégonde About, Elissa K. Deenick, Bertrand Boisson, Jacinta Bustamante, Mélanie Migaud, Bodo Grimbacher, Aziz Bousfiha, Fatima Ailal, Safa Baris, Antoine Guérin, Stuart G. Tangye, Romain Guery, Ning Du, Vimel Rattina

المساهمون: Imagine - Institut des maladies génétiques (IMAGINE - U1163), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Rockefeller University [New York], National Institutes of Health [Bethesda] (NIH), Garvan Institute of Medical Research [Darlinghurst, Australia], University of New South Wales [Sydney] (UNSW), CHU Ibn Rochd [Casablanca], Université Hassan II [Casablanca] (UH2MC), Service d'Immuno-Hémato-Oncologie Pédiatrique, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Shahid Beheshti University of Medical Sciences [Tehran] (SBUMS), Shahid Beheshti University, Universal Scientific Education and Research Network (USERN), Marmara University [Kadıköy - İstanbul], Necmettin Erbakan University [Konya, Turquie], Immunité Innée, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Harvard Medical School [Boston] (HMS), Boston Children's Hospital, Centre d'infectiologie Necker-Pasteur [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Sidra Medicine, Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Freiburg University Medical Center, Sydney children's hospital, Centre de Référence Déficits Immunitaires Héréditaires (CEREDIH), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Necker - Enfants Malades [AP-HP], Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Genetic skin diseases : from disease mechanism to therapies (Equipe Inserm U1163), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de pathologie [CHU Necker], Service d'immuno-hématologie pédiatrique [CHU Necker], Laboratoire de Virologie [CHU Necker], Université Paris Descartes - Paris 5 (UPD5), Centre d'étude des Déficits Immunitaires, University Hospitals Leuven [Leuven], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Istanbul University, Research Center for Immunodeficiencies [Tehran, Iran], Tehran University of Medical Sciences (TUMS), University of New South Wales [Canberra Campus] (UNSW), Howard Hughes Medical Institute [New York], New York University School of Medicine, NYU System (NYU)-NYU System (NYU)-Rockefeller University [New York]-Columbia University Irving Medical Center (CUIMC), This work was supported by grants from INSERM, Paris Descartes University, Laboratoire d’Excellence Integrative Biology of Emerging Infectious Diseases (ANR-10-LABX-62-IBEID), the Jeffrey Modell Foundation Translational Research Program, the French National Research Agency (ANR, grant nos. GENCMCD-ANR-11-BSV3–005-01, HGDIFD-ANR-14-CE15-0006-01, NKIR-ANR-13-PDOC-0025-01, and EURO-CMC-ANR-14-RARE-0005-02), and grants awarded under the 'Investissement d’avenir' program (grant no. ANR-10-IAHU-01), the National Institute of Allergy and Infectious Diseases of the NIH (grant nos. U01AI109697 and R01AI127564), the Rockefeller University, the Howard Hughes Medical Institute, the St. Giles Foundation, the Institut Pasteur, and FP7, under grant agreements 305578 (PathCO) and 317057 (HOMIN). We thank the Centre de Recherche Translationnelle (Institut Pasteur) for technical assistance. V.B. is supported by the ANR (grant no. NKIR-ANR-13-PDOC-0025-01). R.L. is supported by the INSERM Ph.D. program (Poste d’Accueil INSERM), a Fulbright grant (Franco-American commission), and a Philippe Foundation scholarship. Y.Z. received the 'médaille d’or du Centre Hospitalier Universitaire d’Amiens.' Y.W. is supported by the French National Agency for Research on AIDS and Viral Hepatitis (ANRS, grant no. 13318). F. About holds a fellowship from Fondation pour la Recherche Médicale (FRM, grant no. FDM20140630671). A.G. is supported by an IFNGPHOX grant (no. ANR13-ISV3-0001-01) from ANR. B.G. was funded by BMBF (German Federal Ministry of Education and Research) grants 01E01303 and 01ZX1306F. I.M. is supported by a klinische onderzoeks-en opleidingsraad (clinical research council) grant from UZ Leuven, a klinisch onderzoeksfonds (clinical research fund) grant from KU Leuven, and an International Mobility Grant from Fonds voor Wetenschappelijk Onderzoek (fund for scientific research) Vlaanderen. C.S.M., E.K.D., and S.G.T. are supported by grants and fellowships from the National Health and Medical Research Council of Australia. C.S.M., P.G., E.K.D., and S.G.T. are members of CIRCA (Clinical Immunogenomics Research Consortia Australia), which is funded by the Office of Health and Medical Research of the NSW Government, the Jeffrey Modell Foundation, and the John Cook Brown Foundation. A.I.L. is a scholar of the Pasteur-Paris University International Ph.D. program and is supported by a Ph.D. International Training Network grant from the European Union’s Seventh Framework Program under grant agreement no. 317057 (HOMIN). T.A.C. was supported by a grant from the National Institute of Allergy and Infectious Diseases of the NIH (5R01AI065617). S.K. was supported by a grant from the Scientific and Technological Research Council of Turkey (1059B191300622). J.-X.L., P.L., N.D., and W.J.L. were supported by the Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH. A.P. was supported by an AP-HP interface contract., We thank the patients and their families for participating in this study. We thank J. E. Darnell and C. Mertens for advice and for providing reagents. We thank the members of the laboratory, especially F. Jabot-Hanin and V. Pedergnana, for their valuable input on linkage analysis, L. Amar, Y. Nemirovskaya, D. Papandrea, E. Anderson, M. Woollett, C. Desvallées, C. Patissier, and M. Corrias for administrative assistance, E. Jouanguy and Y. Itan for helpful discussions, S. Boucherit for clinical data collection, S. Jacques and the Cochin genomics platform for microarray experiments, and N. Goudin and R. Desveaux of the Necker Institute Imaging Facility., Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Garvan Institute of medical research, Immunité Innée - Innate Immunity, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris] (IP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Sidra Medicine [Doha, Qatar], Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Universitäts Klinikum Freiburg = University Medical Center Freiburg (Uniklinik), Sydney Children's hospital, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Howard Hughes Medical Institute [New York] (HHMI), Howard Hughes Medical Institute (HHMI)-New York University School of Medicine, Institut Pasteur [Paris]-CHU Necker - Enfants Malades [AP-HP], Beziat, Vivien, Li, Juan, Lin, Jian-Xin, Ma, Cindy S., Li, Peng, Bousfiha, Aziz, Pellier, Isabelle, Zoghi, Samaneh, Baris, Safa, Keles, Sevgi, Gray, Paul, Du, Ning, Wang, Yi, Zerbib, Yoann, Levy, Romain, Leclercq, Thibaut, About, Fredegonde, Lim, Ai Ing, Rao, Geetha, Payne, Kathryn, Pelham, Simon J., Avery, Danielle T., Deenick, Elissa K., Pillay, Bethany, Chou, Janet, Guery, Romain, Belkadi, Aziz, Guerin, Antoine, Migaud, Melanie, Rattina, Vimel, Ailal, Fatima, Benhsaien, Ibtihal, Bouaziz, Matthieu, Habib, Tanwir, Chaussabel, Damien, Marr, Nico, El-Benna, Jamel, Grimbacher, Bodo, Wargon, Orli, Bustamante, Jacinta, Boisson, Bertrand, Mueller-Fleckenstein, Ingrid, Fleckenstein, Bernhard, Chandesris, Marie-Olivia, Titeux, Matthias, Fraitag, Sylvie, Alyanakian, Marie-Alexandra, Leruez-Ville, Marianne, Picard, Capucine, Meyts, Isabelle, Di Santo, James P., Hovnanian, Alain, Somer, Ayper, Ozen, Ahmet, Rezaei, Nima, Chatila, Talal A., Abel, Laurent, Leonard, Warren J., Tangye, Stuart G., Puel, Anne, Casanova, Jean-Laurent

المصدر: Science Immunology
Science Immunology, American Association for the Advancement of Science, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩
Science Immunology, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩

مصطلحات موضوعية: 0301 basic medicine, INBORN-ERRORS, Immunoglobulin E, MESH: STAT3 Transcription Factor/immunology, Loss of heterozygosity, PRECISION MEDICINE, Transcription (biology), OF-FUNCTION MUTATIONS, STAT3, MESH: Transcription Factors/metabolism, CELL-DIFFERENTIATION, MESH: Th2 Cells/metabolism, MESH: Immunoglobulin E/immunology, MESH: Middle Aged, MESH: Gene Expression Regulation/immunology, Cell Differentiation, General Medicine, MESH: RNA, Messenger/metabolism, MESH: Immunoglobulin E/blood, MESH: Zinc Fingers/genetics, READ ALIGNMENT, MESH: Transcription, Genetic/immunology, MESH: Cell Nucleus/metabolism, MESH: Young Adult, [SDV.IMM]Life Sciences [q-bio]/Immunology, SIGNAL TRANSDUCER, Job Syndrome, MESH: Homozygote, STAT3 Transcription Factor, Cell type, MESH: Lymphocyte Count, MESH: Pedigree, MESH: STAT3 Transcription Factor/genetics, Immunology, Biology, Article, MESH: Job Syndrome/immunology, MESH: Genes, Recessive/genetics, DIFFERENTIAL EXPRESSION, MESH: Genes, Recessive/immunology, MESH: Job Syndrome/blood, MESH: Transcription Factors/genetics, 03 medical and health sciences, MESH: Whole Exome Sequencing, MESH: Exons/genetics, Humans, Transcription factor, Gene, MESH: Adolescent, MESH: Consanguinity, MESH: Humans, CLINICAL-FEATURES, MESH: Th17 Cells/metabolism, MESH: Th17 Cells/immunology, MESH: Cytokines/immunology, MESH: Adult, MESH: Loss of Function Mutation, MESH: Job Syndrome/genetics, MESH: Cell Differentiation/genetics, Molecular biology, MESH: Male, MESH: Th2 Cells/immunology, IL-21 RECEPTOR, 030104 developmental biology, Gene Expression Regulation, MESH: STAT3 Transcription Factor/metabolism, MESH: Promoter Regions, Genetic/genetics, MESH: Cell Differentiation/immunology, T-CELLS, STAT protein, biology.protein, Th17 Cells, MESH: Transcription Factors/immunology, MESH: Cytokines/metabolism, MESH: Female

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a014e03bf19bbdfb4eb205a53e190a3aTest
https://doi.org/10.1126/sciimmunol.aat4956Test