المؤلفون: Gevrenova, Reneta, Zaharieva, Maya, Kroumov, Alexander, Voutquenne-Nazabadioko, Laurence, Zheleva-Dimitrova, Dimitrina, Balabanova, Vessela, Hajdenski, Hristo, Konstantinov, Spiro

المساهمون: Medical University of Sofia Bulgarie, Institut Stephan Angeloff, Réseau International des Instituts Pasteur (RIIP), Bulgarian Academy of Sciences (BAS), Institut de Chimie Moléculaire de Reims - UMR 7312 (ICMR), Université de Reims Champagne-Ardenne (URCA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA)-Université de Reims Champagne-Ardenne (URCA)-Centre National de la Recherche Scientifique (CNRS)-SFR Condorcet, Université de Reims Champagne-Ardenne (URCA)-Centre National de la Recherche Scientifique (CNRS)-Université de Reims Champagne-Ardenne (URCA)-Centre National de la Recherche Scientifique (CNRS), This study is financially supported by Project Д-76/May 03, 2018, Council of Medical Science at Medical University - Sofia, Bulgaria., We thank Andrea Balukova (student, Bioprocessing of New Medicines, Department of Biochemical Engineering, UCL) for her devoted work on the in vitro cytotoxicity tests performed in the framework of her student's summer praxis. The fluorimetric measurements were performed with the kind support of Prof. Galya Staneva at the Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences.

المصدر: ISSN: 0278-6915 ; Food and Chemical Toxicology ; https://hal.univ-reims.fr/hal-02430957Test ; Food and Chemical Toxicology, 2019, 133, pp.110777. ⟨10.1016/j.fct.2019.110777⟩.

مصطلحات موضوعية: GOTCAB saponins, Gypsophila trichotoma, Etoposide, Synergism, Apoptosis, ROS, MESH: Antineoplastic Agents/chemistry, MESH: Antineoplastic Agents/pharmacology, MESH: Drug Synergism, MESH: Etoposide/pharmacology, MESH: Humans, MESH: Molecular Structure, MESH: Plant Roots/chemistry, MESH: Reactive Oxygen Species/metabolism, MESH: Saponins/chemistry, MESH: Saponins/pharmacology, MESH: Triterpenes/chemistry, MESH: Triterpenes/pharmacology, MESH: Apoptosis/drug effects, MESH: Caryophyllaceae/chemistry, MESH: Cell Line, Tumor, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31472227; hal-02430957; https://hal.univ-reims.fr/hal-02430957Test; https://hal.univ-reims.fr/hal-02430957/documentTest; https://hal.univ-reims.fr/hal-02430957/file/Gypsophila%20saponins%20enhanced%20the%20cytotoxicity%20of%20ethoposide_Revision_1_HAL.pdfTest; PUBMED: 31472227

الإتاحة: https://doi.org/10.1016/j.fct.2019.110777Test
https://hal.univ-reims.fr/hal-02430957Test
https://hal.univ-reims.fr/hal-02430957/documentTest
https://hal.univ-reims.fr/hal-02430957/file/Gypsophila%20saponins%20enhanced%20the%20cytotoxicity%20of%20ethoposide_Revision_1_HAL.pdfTest

المؤلفون: Amiable, Claire, Paoletti, Julie, Haouz, Ahmed, Padilla, André, Labesse, Gilles, Kaminski, Pierre-Alexandre, Pochet, Sylvie

المساهمون: Université Paris Descartes - Paris 5 (UPD5), Chimie et Biocatalyse, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), This work was supported by grants from the Fondation pour la Recherche Médicale (DCM20111223063 to S. Pochet), Institut Pasteur, CNRS, INSERM and the French Infrastructure for Integrated Structural Biology (FRISBI, ANR-10-INSB-05-01)., ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)

المصدر: ISSN: 0223-5234.

مصطلحات موضوعية: Cancer, Cross-coupling reaction, Crystal structure, DNPH1, Inhibitor, Nucleoside analogues, MESH: Animals, MESH: Antineoplastic Agents/chemical synthesis, MESH: Enzyme Inhibitors/chemistry, MESH: Enzyme Inhibitors/metabolism, MESH: Enzyme Inhibitors/pharmacology, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Molecular Targeted Therapy, MESH: N-Glycosyl Hydrolases/antagonists & inhibitors, MESH: N-Glycosyl Hydrolases/chemistry, MESH: N-Glycosyl Hydrolases/metabolism, MESH: Nuclear Proteins/antagonists & inhibitors, MESH: Antineoplastic Agents/chemistry, MESH: Nuclear Proteins/chemistry, MESH: Nuclear Proteins/metabolism, MESH: Protein Conformation, MESH: Proto-Oncogene Proteins/antagonists & inhibitors, MESH: Proto-Oncogene Proteins/chemistry, MESH: Proto-Oncogene Proteins/metabolism, MESH: Purine Nucleotides/chemical synthesis, MESH: Purine Nucleotides/chemistry, MESH: Purine Nucleotides/metabolism, MESH: Purine Nucleotides/pharmacology, MESH: Antineoplastic Agents/metabolism

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/25108359; pasteur-01483767; https://pasteur.hal.science/pasteur-01483767Test; PUBMED: 25108359

الإتاحة: https://doi.org/10.1016/j.ejmech.2014.07.110Test
https://pasteur.hal.science/pasteur-01483767Test

المؤلفون: Martin Soucé, Juliette Gautier, Katel Hervé-Aubert, Igor Chourpa, Emilie Allard-Vannier

المساهمون: Nanomédicaments et Nanosondes, EA 6295 (NMNS), Université de Tours, Université de Tours (UT)

المصدر: Nanotechnology
Nanotechnology, Institute of Physics, 2013, 24 (43), pp.432002. ⟨10.1088/0957-4484/24/43/432002⟩

مصطلحات موضوعية: Polymers, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, MESH: Ferric Compounds/chemistry, Metal Nanoparticles, Nanoparticle, 02 engineering and technology, Ferric Compounds, MESH: Colloids/chemical synthesis, General Materials Science, MESH: Static Electricity, Targeting ligands, Drug Carriers, 0303 health sciences, Coating materials, MESH: Hydrophobic and Hydrophilic Interactions, 021001 nanoscience & nanotechnology, MESH: Antineoplastic Agents/chemistry, MESH: Drug Carriers, Mechanics of Materials, Colloidal gold, MESH: Doxorubicin/chemistry, MESH: Doxorubicin/administration & dosage, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, Materials science, Nanostructure, Surface Properties, Static Electricity, MESH: Liposomes/chemistry, Antineoplastic Agents, Bioengineering, Nanotechnology, MESH: Metal Nanoparticles/chemistry, 03 medical and health sciences, MESH: Polymers/chemistry, [SDV.SP.MED]Life Sciences [q-bio]/Pharmaceutical sciences/Medication, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Colloids, Electrical and Electronic Engineering, Metal nanoparticles, [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials, 030304 developmental biology, MESH: Surface Properties, Mechanical Engineering, General Chemistry, MESH: Antineoplastic Agents/administration & dosage, Doxorubicin, Liposomes, Surface modification, Nanocarriers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80b3c000279a31e169427f139bf3dffTest
https://hal-univ-tours.archives-ouvertes.fr/hal-01128463Test

المؤلفون: Gautier, Juliette, Munnier, Emilie, Douziech-Eyrolles, Laurence, Paillard, Archibald, Dubois, Pierre, Chourpa, Igor

المساهمون: Nanomédicaments et Nanosondes (NMNS), Université de Tours (UT)

المصدر: ISSN: 0003-2654.

مصطلحات موضوعية: MESH: Antineoplastic Agents/chemistry, MESH: Doxorubicin/chemistry, MESH: Drug Carriers, MESH: Ferrous Compounds/chemistry, MESH: Nanostructures, MESH: Spectrum Analysis/methods, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging

العلاقة: hal-01119642; https://univ-tours.hal.science/hal-01119642Test

الإتاحة: https://doi.org/10.1039/c3an00787aTest
https://univ-tours.hal.science/hal-01119642Test

المؤلفون: Gautier, Juliette, Allard-Vannier, Emilie, Hervé-Aubert, Katel, Soucé, Martin, Chourpa, Igor

المساهمون: Nanomédicaments et Nanosondes (NMNS), Université de Tours (UT)

المصدر: ISSN: 0957-4484.

مصطلحات موضوعية: MESH: Antineoplastic Agents/administration & dosage, MESH: Antineoplastic Agents/chemistry, MESH: Hydrophobic and Hydrophilic Interactions, MESH: Liposomes/chemistry, MESH: Metal Nanoparticles/chemistry, MESH: Polymers/chemistry, MESH: Static Electricity, MESH: Surface Properties, MESH: Colloids/chemical synthesis, MESH: Doxorubicin/administration & dosage, MESH: Doxorubicin/chemistry, MESH: Drug Carriers, MESH: Ferric Compounds/chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, [SDV.SP.MED]Life Sciences [q-bio]/Pharmaceutical sciences/Medication

العلاقة: hal-01128463; https://univ-tours.hal.science/hal-01128463Test

الإتاحة: https://doi.org/10.1088/0957-4484/24/43/432002Test
https://univ-tours.hal.science/hal-01128463Test