المؤلفون: Tandon, Himani, de Brevern, Alexandre, Srinivasan, Narayanaswamy

المساهمون: Molecular Biophysics Unit Bangalore, India (MBU), Indian Institute of Science (IISc), Biologie Intégrée du Globule Rouge (BIGR (UMR_S_1134 / U1134)), Institut National de la Transfusion Sanguine Paris (INTS)-Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pointe-à-Pitre / Abymes Guadeloupe -Université des Antilles (UA)-Université Paris Cité (UPCité), Institut National de la Transfusion Sanguine Paris (INTS), Indo-French Centre for the Promotion of Advanced Research / CEFIPRA for collaborative grant (number 5302-2), DBT-COE, Ministry of Human Resource Development, DST-FIST, UGC Center for Advanced Study, Bioinformatics and Computational Biology centre support from DBT, DBT-IISc Partnership Program, ANR-18-IDEX-0001, ANR-11- LABX-0051, ANR-11-IDEX- 0005-02, ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), ANR-11-LABX-0051,GR-Ex,Biogenèse et pathologies du globule rouge(2011), ANR-11-IDEX-0005,USPC,Université Sorbonne Paris Cité(2011)

المصدر: ISSN: 0969-2126 ; Structure ; https://inserm.hal.science/inserm-03543689Test ; Structure, 2021, 29 (4), pp.371-384.e3. ⟨10.1016/j.str.2020.11.015⟩.

مصطلحات موضوعية: allostery, bioinformatics, functional analysis, normal mode analysis, protein dynamics, protein structure, protein-protein interactions, MESH: Allosteric Site, MESH: Cyclophilin A, MESH: Deoxyribonucleases, Type I Site-Specific, MESH: Humans, MESH: Molecular Dynamics Simulation, MESH: Protein Binding, MESH: Protein Interaction Mapping, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33306961; inserm-03543689; https://inserm.hal.science/inserm-03543689Test; https://inserm.hal.science/inserm-03543689/documentTest; https://inserm.hal.science/inserm-03543689/file/Tandon_et_al_Structure_2021_forHAL-small.pdfTest; PUBMED: 33306961

الإتاحة: https://doi.org/10.1016/j.str.2020.11.015Test
https://inserm.hal.science/inserm-03543689Test
https://inserm.hal.science/inserm-03543689/documentTest
https://inserm.hal.science/inserm-03543689/file/Tandon_et_al_Structure_2021_forHAL-small.pdfTest

المؤلفون: Lara, Julia, Diacovich, Lautaro, Trajtenberg, Felipe, Larrieux, Nicole, Malchiodi, Emilio, L., Fernández, Marisa, M., Gago, Gabriela, Gramajo, Hugo, Buschiazzo, Alejandro

المساهمون: Universidad Nacional de Rosario Santa Fe, Plataforma de Biología Estructural y Metabolómica Rosario (PLABEM), Molecular and structural microbiology / Microbiología Molecular y Estructural Montevideo, Institut Pasteur de Montevideo, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Universidad de Buenos Aires Buenos Aires (UBA), Integrative Microbiology of Zoonotic Agents Paris and Montevideo (IMiZA), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut Pasteur Paris (IP), J.L. traineeships at IPasteur-Montevideo were funded by CeBEM. Support to A.B. from Institut Pasteur (grant 761-International_Joint_Research_Unit-IMiZA-2016), to G.G. from ANPCyT (grant PICT 2015-0796) and to H.G. from ANPCyT (grants PICT 2012-0168 and 2022) and NIH (grant 1R01AI095183-01) are acknowledged., We thank Stanislas Leibler, Michael Mitchell and Pablo Sartori for sharing initial strain analysis scripts, Matias Machado for assistance in molecular dynamics, Frank Lehmann for initial cloning efforts, Sebastian Klinke (Fundación Leloir) and the staff at Proxima 1 beamline (Soleil synchrotron) and at I04-1 beamline (Diamond synchrotron) for assistance with data collection. We acknowledge computational and storage services (TARS cluster) provided by the Institut Pasteur IT Dept (Paris). We thank the CCP4/CeBEM Macromolecular Crystallography School (USP@São Carlos, 2018), especially Isabel Usón and Paul Emsley for helping us, respectively, with ShelxE and Coot, in dealing with low-resolution density modification and model building.

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: MESH: Acyl Coenzyme A, MESH: Allosteric Site, MESH: Fatty Acids, MESH: Ligands, MESH: Models, Molecular, MESH: Mycobacterium tuberculosis, MESH: Protein Conformation, MESH: Transcription Factors, MESH: Bacterial Proteins, MESH: Cell Wall, MESH: Crystallography, X-Ray, MESH: DNA, Bacterial, MESH: DNA-Binding Proteins, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [CHIM.CRIS]Chemical Sciences/Cristallography, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32710080; pasteur-03246643; https://pasteur.hal.science/pasteur-03246643Test; https://pasteur.hal.science/pasteur-03246643/documentTest; https://pasteur.hal.science/pasteur-03246643/file/s41467-020-17504-x.pdfTest; PUBMED: 32710080; PUBMEDCENTRAL: PMC7382501

الإتاحة: https://doi.org/10.1038/s41467-020-17504-xTest
https://pasteur.hal.science/pasteur-03246643Test
https://pasteur.hal.science/pasteur-03246643/documentTest
https://pasteur.hal.science/pasteur-03246643/file/s41467-020-17504-x.pdfTest

المؤلفون: Coutard, Bruno, Barral, Karine, Lichiere, Julie, Selisko, Barbara, Martin, Baptiste, Aouadi, Wahiba, Lombardia, Miguel Ortiz, Debart, Françoise, Vasseur, Jean-Jacques, Guillemot, Jean Claude, Canard, Bruno, Decroly, Etienne

المساهمون: Architecture et fonction des macromolécules biologiques (AFMB), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes (IPC), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Information génomique et structurale (IGS), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0022-538X.

مصطلحات موضوعية: protein structure-function, methyltransferase, RNA processing, Zika virus, flavivirus, MESH: Allosteric Site, MESH: Antiviral Agents, MESH: Drug Design, MESH: Escherichia coli, MESH: Hydrogen Bonding, MESH: Methyltransferases, MESH: Models, Molecular, MESH: Protein Binding, MESH: Viral Nonstructural Proteins, MESH: Zika Virus, MESH: Catalytic Domain, MESH: Crystallography, X-Ray, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28031359; hal-01802793; https://hal.science/hal-01802793Test; https://hal.science/hal-01802793/documentTest; https://hal.science/hal-01802793/file/J.%20Virol.-2017-Coutard-.pdfTest; PUBMED: 28031359

الإتاحة: https://doi.org/10.1128/JVI.02202-16Test
https://hal.science/hal-01802793Test
https://hal.science/hal-01802793/documentTest
https://hal.science/hal-01802793/file/J.%20Virol.-2017-Coutard-.pdfTest

المؤلفون: Canul-Tec, Juan, Assal, Reda, Cirri, Erica, Legrand, Pierre, Brier, Sébastien, Chamot-Rooke, Julia, Reyes, Nicolas

المساهمون: Mécanismes moléculaires du transport membranaire - Molecular mechanisms of membrane transport, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Spectrométrie de Masse pour la Biologie – Mass Spectrometry for Biology (UTechS MSBio), Institut Pasteur Paris (IP)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), The work was funded by the ERC Starting grant 309657 (N.R.). Further support from G5 Institut Pasteur funds (N.R.), CACSICE grant (ANR-11-EQPX-008), and CNRS UMR3528 (N.R., J.C.-R.) is acknowledged., We thank O. Boudker for comments on the manuscript and discussion on consensus mutagenesis, P. V. Krasteva for comments on the manuscript, A. Haouz and the staff at the crystallogenesis core facility of the Institut Pasteur for assistance with crystallization screens, Staff at Synchrotron SOLEIL and the European Synchrotron Radiation Facility for assistance with data collection, D. O’Brien for discussion of HDX results., ANR-11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), European Project: 309657,EC:FP7:ERC,ERC-2012-StG_20111109,HEAATS(2012)

المصدر: ISSN: 0028-0836.

مصطلحات موضوعية: Membrane proteins, Molecular neuroscience, Permeation and transport, MESH: Allosteric Regulation, MESH: Allosteric Site, MESH: Crystallization, MESH: Crystallography, X-Ray, MESH: Deuterium Exchange Measurement, MESH: Excitatory Amino Acid Transporter 1, MESH: Humans, MESH: Mass Spectrometry, MESH: Models, Molecular, MESH: Protein Domains, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28424515; info:eu-repo/grantAgreement/EC/FP7/309657/EU/Molecular bases of human excitatory neurotransmitter transport across the plasma membrane/HEAATS; pasteur-01655604; https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604Test; https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/documentTest; https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/file/Canul-Tech-etal_nature_accepted_HAL.pdfTest; PUBMED: 28424515; PUBMEDCENTRAL: PMC5410168

الإتاحة: https://doi.org/10.1038/nature22064Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/documentTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-01655604/file/Canul-Tech-etal_nature_accepted_HAL.pdfTest

المؤلفون: Marisa M. Fernández, Felipe Trajtenberg, Hugo Gramajo, Lautaro Diacovich, Nicole Larrieux, Gabriela Gago, Julia Lara, Emilio L. Malchiodi, Alejandro Buschiazzo

المساهمون: Universidad Nacional de Rosario [Santa Fe], Plataforma de Biología Estructural y Metabolómica [Rosario] (PLABEM), Molecular and structural microbiology / Microbiología Molecular y Estructural [Montevideo], Institut Pasteur de Montevideo, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Universidad de Buenos Aires [Buenos Aires] (UBA), Integrative Microbiology of Zoonotic Agents [Paris and Montevideo] (IMiZA), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut Pasteur [Paris], J.L. traineeships at IPasteur-Montevideo were funded by CeBEM. Support to A.B. from Institut Pasteur (grant 761-International_Joint_Research_Unit-IMiZA-2016), to G.G. from ANPCyT (grant PICT 2015-0796) and to H.G. from ANPCyT (grants PICT 2012-0168 and 2022) and NIH (grant 1R01AI095183-01) are acknowledged., We thank Stanislas Leibler, Michael Mitchell and Pablo Sartori for sharing initial strain analysis scripts, Matias Machado for assistance in molecular dynamics, Frank Lehmann for initial cloning efforts, Sebastian Klinke (Fundación Leloir) and the staff at Proxima 1 beamline (Soleil synchrotron) and at I04-1 beamline (Diamond synchrotron) for assistance with data collection. We acknowledge computational and storage services (TARS cluster) provided by the Institut Pasteur IT Dept (Paris). We thank the CCP4/CeBEM Macromolecular Crystallography School (USP@São Carlos, 2018), especially Isabel Usón and Paul Emsley for helping us, respectively, with ShelxE and Coot, in dealing with low-resolution density modification and model building., Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut Pasteur [Paris] (IP)

المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3703. ⟨10.1038/s41467-020-17504-x⟩
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, 2020, 11 (1), pp.3703. ⟨10.1038/s41467-020-17504-x⟩

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, MESH: Mycobacterium tuberculosis, Protein Conformation, General Physics and Astronomy, Crystallography, X-Ray, Ligands, chemistry.chemical_compound, Protein structure, MESH: Protein Conformation, Cell Wall, MESH: Ligands, lcsh:Science, MESH: Allosteric Site, MESH: Bacterial Proteins, Multidisciplinary, biology, Effector, Fatty Acids, MESH: Transcription Factors, 3. Good health, Cell biology, MESH: Fatty Acids, DNA-Binding Proteins, Structural biology, Transcription, Allosteric Site, MESH: Models, Molecular, DNA, Bacterial, Science, Allosteric regulation, Protein dimer, Bacterial physiology, Article, General Biochemistry, Genetics and Molecular Biology, Mycobacterium tuberculosis, 03 medical and health sciences, Acyl-CoA, MESH: Cell Wall, Bacterial Proteins, Lipid biosynthesis, MESH: Acyl Coenzyme A, [CHIM.CRIS]Chemical Sciences/Cristallography, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], 030102 biochemistry & molecular biology, General Chemistry, biology.organism_classification, MESH: Crystallography, X-Ray, MESH: DNA, Bacterial, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, 030104 developmental biology, chemistry, lcsh:Q, Acyl Coenzyme A, DNA, MESH: DNA-Binding Proteins, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0c9ff504288d18e5194304c77d818dTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-03246643/documentTest

المؤلفون: Himani Tandon, Narayanaswamy Srinivasan, Alexandre G. de Brevern

المساهمون: Molecular Biophysics Unit [Bangalore, India] (MBU), Indian Institute of Science, Biologie Intégrée du Globule Rouge (BIGR (UMR_S_1134 / U1134)), Institut National de la Transfusion Sanguine [Paris] (INTS)-Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pointe-à-Pitre/Abymes [Guadeloupe] -Université des Antilles (UA)-Université Paris Cité (UPCité), Institut National de la Transfusion Sanguine [Paris] (INTS), Indo-French Centre for the Promotion of Advanced Research / CEFIPRA for collaborative grant (number 5302-2), DBT-COE, Ministry of Human Resource Development, DST-FIST, UGC Center for Advanced Study, Bioinformatics and Computational Biology centre support from DBT, DBT-IISc Partnership Program, ANR-18-IDEX-0001, ANR-11- LABX-0051, ANR-11-IDEX- 0005-02, de Brevern, Alexandre G.

المصدر: Structure
Structure, Elsevier (Cell Press), 2021, 29 (4), pp.371-384.e3. ⟨10.1016/j.str.2020.11.015⟩

مصطلحات موضوعية: Association (object-oriented programming), [SDV]Life Sciences [q-bio], Allosteric regulation, protein-protein interactions, Molecular Dynamics Simulation, MESH: Deoxyribonucleases, Type I Site-Specific, Protein–protein interaction, functional analysis, 03 medical and health sciences, Protein structure, Structural Biology, Protein Interaction Mapping, MESH: Protein Binding, Humans, MESH: Molecular Dynamics Simulation, protein structure, skin and connective tissue diseases, MESH: Allosteric Site, Molecular Biology, 030304 developmental biology, 0303 health sciences, allostery, MESH: Humans, Chemistry, Protein dynamics, MESH: Cyclophilin A, 030302 biochemistry & molecular biology, Dynamics (mechanics), MESH: Protein Interaction Mapping, Deoxyribonucleases, Type I Site-Specific, bioinformatics, Protein tertiary structure, [SDV] Life Sciences [q-bio], Structural change, normal mode analysis, protein dynamics, Biophysics, sense organs, Cyclophilin A, Allosteric Site, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf16d0a5f884b5bcd9ff0a578b2e7b6Test
https://pubmed.ncbi.nlm.nih.gov/33306961Test

المؤلفون: Swapna, Lakshmipuram, S., Mahajan, Swapnil, de Brevern, Alexandre, Srinivasan, Narayanaswamy

المساهمون: Molecular Biophysics Unit, Indian Institute of Science (IISc), Dynamique des Structures et Interactions des Macromolécules Biologiques - Pôle de La Réunion (DSIMB Réunion), Biologie Intégrée du Globule Rouge (BIGR (UMR_S_1134 / U1134)), Institut National de la Transfusion Sanguine Paris (INTS)-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université des Antilles (UA)-Institut National de la Transfusion Sanguine Paris (INTS)-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université des Antilles (UA), Dynamique des Structures et Interactions des Macromolécules Biologiques (DSIMB), Institut National de la Transfusion Sanguine Paris (INTS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), This research is supported by Indo-French collaborative grant (CEFIPRA/IFCPAR number 3903-E) between AdB and NS. Part of this project is also supported for NS by Department of Biotechnology (DBT). Part of this was supported for AdB by grants from the Ministry of Research, University Paris Diderot - Paris 7, National Institute for Blood Transfusion (INTS) and the Institute for Health and Medical Research (INSERM).

المصدر: ISSN: 1472-6807 ; BMC Structural Biology ; https://inserm.hal.science/inserm-00725334Test ; BMC Structural Biology, 2012, 12 (1), pp.6. ⟨10.1186/1472-6807-12-6⟩.

مصطلحات موضوعية: MESH: Allosteric Site, MESH: Animals, MESH: Databases, Protein, MESH: Ligands, MESH: Models, Molecular, MESH: Protein Binding, MESH: Protein Structure, Tertiary, MESH: Proteins, MESH: Signal Transduction, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/22554255; inserm-00725334; https://inserm.hal.science/inserm-00725334Test; https://inserm.hal.science/inserm-00725334/documentTest; https://inserm.hal.science/inserm-00725334/file/1472-6807-12-6.pdfTest; PUBMED: 22554255

الإتاحة: https://doi.org/10.1186/1472-6807-12-6Test
https://inserm.hal.science/inserm-00725334Test
https://inserm.hal.science/inserm-00725334/documentTest
https://inserm.hal.science/inserm-00725334/file/1472-6807-12-6.pdfTest

المؤلفون: Laine, Elodie, Martínez, Leandro, Ladant, Daniel, Malliavin, Thérèse, Blondel, Arnaud

المساهمون: École normale supérieure - Cachan (ENS Cachan), Universidade de São Paulo = University of São Paulo (USP), Biochimie des Interactions Macromoléculaires / Biochemistry of Macromolecular Interactions, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Bioinformatique structurale - Structural Bioinformatics, The authors would like to thank W.-J. Tang, A. Lesnard, and S. Rault for their collaboration and active support in sharing thoughts and materials. LM acknowledges FAPESP (Process number 2010/1694-7) for financial support. EL acknowledges OSEO, French State agency for innovation, for financial support. We acknowledge the French National Supercomputing Centers Institut du Développement et des Ressources en Informatique Scientifique (IDRIS, Orsay) and Centre Informatique National de l’Enseignement Supérieur (CINES, Montpellier) for computational resources. We also acknowledge (EL, TM, AB) support by the French Ministry of Defense, Direction Générale pour l’Armement/Mission pour la Recherche et l’Innovation Scientifique (DGA/MRIS), the National Scientific Research Center, Centre National de la Recherche Scientifique (CNRS), (all) the Institut Pasteur, and (LM) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, Brazil).

المصدر: EISSN: 2072-6651 ; Toxins ; https://pasteur.hal.science/pasteur-01459064Test ; Toxins, 2012, 4, pp.580-604. ⟨10.3390/toxins4080580⟩

مصطلحات موضوعية: Edema factor, allostery, anthrax, molecular modeling, transition path, virtual screening, MESH: Allosteric Site, MESH: Antigens, Bacterial, MESH: Bacterial Toxins, MESH: Calcium, MESH: Calmodulin, MESH: Models, Molecular, MESH: Molecular Conformation, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/23012649; pasteur-01459064; https://pasteur.hal.science/pasteur-01459064Test; https://pasteur.hal.science/pasteur-01459064/documentTest; https://pasteur.hal.science/pasteur-01459064/file/129%20LAINE%20E.pdfTest; PUBMED: 23012649

الإتاحة: https://doi.org/10.3390/toxins4080580Test
https://pasteur.hal.science/pasteur-01459064Test
https://pasteur.hal.science/pasteur-01459064/documentTest
https://pasteur.hal.science/pasteur-01459064/file/129%20LAINE%20E.pdfTest

المؤلفون: Goudet, Cyril, Kniazeff, Julie, Hlavackova, Veronika, Malhaire, Fanny, Maurel, Damien, Acher, Francine, Blahos, Jaroslav, Prézeau, Laurent, Pin, Jean-Philippe

المساهمون: Institut de Génomique Fonctionnelle (IGF), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Czech Academy of Sciences Prague (CAS), CIS BIOINTERNATIONAL, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), This work was supported in part by grants from the CNRS, the Action Concertée Incitative “Molécules et Cibles Thérapeutiques” of the French ministry of research and technology, the fondation Paul Hamel, the comité Parkinson from the Fondation de France, Addex pharmaceuticals and the European Community (Grant LSHB-CT-200-503337) (to J.-P. P.) and by the Grant Agency of Czech Republic (GACR 301/03/1183 and 301/03/H095), Grant Agency Academy of Science of Czech Republic (KJB5039402), and AVOZ 50390512 (to J. B.). CG is supported by a fellowship from the Fondation pour la Recherche Médicale. JK is supported by a bourse de Docteur Ingénieur from the CNRS. DM is supported by both CisBio International and the French government (CIFRE fellowship).

المصدر: ISSN: 0021-9258.

مصطلحات موضوعية: MESH: Actins, MESH: Allosteric Site, MESH: Point Mutation, MESH: Protein Binding, MESH: Receptors, GABA-B, MESH: Protein Conformation, G-Protein-Coupled, Metabotropic Glutamate, MESH: Binding, Competitive, MESH: Recombinant Fusion Proteins, MESH: Time Factors, MESH: Cell Line, MESH: Enzyme-Linked Immunosorbent Assay, MESH: Cell Membrane, MESH: Dimerization, MESH: Fluorescence Resonance Energy Transfer, MESH: Inositol Phosphates, MESH: GTP-Binding Proteins, MESH: Humans, MESH: Models, Biological, MESH: Mutagenesis, Site-Directed, MESH: Plasmids, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/15863499; inserm-00318925; https://inserm.hal.science/inserm-00318925Test; https://inserm.hal.science/inserm-00318925/documentTest; https://inserm.hal.science/inserm-00318925/file/2005_Goudet_et_al_JBC_dimeric_mGluRs_PAMs.pdfTest; PUBMED: 15863499

الإتاحة: https://doi.org/10.1074/jbc.M502642200Test
https://inserm.hal.science/inserm-00318925Test
https://inserm.hal.science/inserm-00318925/documentTest
https://inserm.hal.science/inserm-00318925/file/2005_Goudet_et_al_JBC_dimeric_mGluRs_PAMs.pdfTest

المؤلفون: Seeliger, Markus A., Spichty, Martin, Kelly, Sadie E., Bycroft, Mark, Freund, Stefan M.V., Karplus, Martin, Itzhaki, Laura S.

المساهمون: MRC Centre for Protein Engineering, Department of Chemistry and Chemical Biology Harvard, Harvard University, Institut de Science et d'ingénierie supramoléculaires (ISIS), Université de Strasbourg (UNISTRA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0021-9258.

مصطلحات موضوعية: APC, anaphase promoting complex, Cdk2, Cyclin dependent kinase 2, Cks, Cyclin dependent kinase subunit, HSQC, heteronuclear single quantum coherence, MD, molecular dynamics, NOESY, nuclear Overhauser enhancement spectroscopy, SCF, Skp-Cullin-F-box proteins, Skp2, S-phase Kinase associated protein, TOCSY, total correlation spectroscopy, TROSY, transverse relaxation-optimised spectroscopy, MESH: Allosteric Site, MESH: Binding Sites, MESH: Multiprotein Complexes, MESH: Phosphorylation, MESH: CDC2-CDC28 Kinases, MESH: Protein Binding, MESH: Protein Conformation, MESH: Protein Kinases, MESH: Protein Structure, Secondary

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/15772084; hal-03026515; https://hal.science/hal-03026515Test; https://hal.science/hal-03026515/documentTest; https://hal.science/hal-03026515/file/JBiolChem.pdfTest; PUBMED: 15772084

الإتاحة: https://doi.org/10.1074/jbc.M501450200Test
https://hal.science/hal-03026515Test
https://hal.science/hal-03026515/documentTest
https://hal.science/hal-03026515/file/JBiolChem.pdfTest