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المؤلفون: Rui Sun, Clara Abraham
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 4, Pp 673-697 (2020)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Th, T-helper cell, Interleukin-23, 0302 clinical medicine, MDMs, monocyte-derived macrophages, Macrophage, Cells, Cultured, Original Research, GFP, green fluorescent protein, TNF, tumor necrosis factor, Janus kinase 2, IBD, inflammatory bowel disease, biology, Chemistry, TYK2, Tyrosine kinase 2, Gastroenterology, Nitric oxide synthase 2, PI3K, phosphatidylinositol 3-kinase, Cell biology, LC3II, light chain 3-II, STAT, signal transducer and activator of transcription, Interleukin 12, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, JAK, Janus kinase, Infection, NK, natural killer, Intracellular, Crohn’s Disease, PRR, pattern-recognition receptor, Cell Line, NOD, nucleotide-binding oligomerization domain, RNS, reactive nitrogen species, 03 medical and health sciences, Paracrine signalling, ROS, reactive oxygen species, Immune system, PDK1, pyruvate dehydrogenase kinase 1, Autophagy, Genetics, Humans, Point Mutation, Ulcerative Colitis, IFN, interferon, lcsh:RC799-869, NOS2, nitric oxide synthase 2, Autocrine signalling, Bacteria, Hepatology, Macrophages, Receptors, Interleukin, NADPH, nicotinamide adenine dinucleotide phosphate, Inflammatory Bowel Diseases, IL, interleukin, 030104 developmental biology, siRNA, small interfering RNA, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, AIEC, adherent invasive Escherichia coli
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad178b92adfc5ec39a7be2f0f160e40Test
https://doi.org/10.1016/j.jcmgh.2020.05.007Test -
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المؤلفون: Zhenliang Zhu, Han Jing, Jingcheng Zhang, Teng Wu, Yuanpeng Gao, Yongke Wei, Yong Zhang, Mengke Yuan, Zikun Yuan
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, KI, knock-in, DNA End-Joining Repair, homology-mediated end joining (HMEJ), indels, inserts and/or deletions, mammal, Biochemistry, Genome editing, MDMs, monocyte-derived macrophages, GAPDH, glyceraldehyde 3-Phosphate dehydrogenase, CRISPR, gene transfer, ROSA26, HDR, homology-directed repair, Disease Resistance, genomic safe harbors (GSHs), Gene Editing, qPCR, quantitative real-time PCR, Methods and Resources, EGFP, enhanced green fluorescent protein, tuberculosis, HAs, homology arms, Livestock, MMEJ, microhomology-mediated end-joining, NRAMP1, natural resistance-associated macrophage protein-1, DSBs, double-strand breaks, infectious disease, Cloning, Organism, Computational biology, Biology, Homology directed repair, bROSA26, bovine ROSA26, 03 medical and health sciences, GSHs, genomic safe harbors, HMEJ, homology-mediated end joining, Gene knockin, CB, cytochalasin B, Animals, Molecular Biology, Gene, CRISPR/Cas9, BFFs, bovine fetal fibroblasts, PBMCs, peripheral blood mononuclear cells, Reporter gene, COCs, cumulus–oocyte complexes, 030102 biochemistry & molecular biology, business.industry, Cas9, SCNT, somatic cell nuclear transfer, Cell Biology, livestock, 030104 developmental biology, Genetic Loci, NHEJ, nonhomologous end-joining, Cattle, HR, homologous recombination, business, SA, splice acceptor, Tuberculosis, Bovine, Cre, Cre recombinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285c994d75cadedd116ca9a24a9fc5b4Test
http://europepmc.org/articles/PMC8038940Test -
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المؤلفون: Louise China, Nekisa Zakeri, Tu Vinh Long, Alexander A. Maini, Amit Patel, Thais Helena Tittanegro, Alastair O'Brien, Roel P.H. De Maeyer, Natalia Becares, Derek W. Gilroy, Lucy Ly
المصدر: JHEP Reports, Vol 3, Iss 6, Pp 100332-(2021)
JHEP Reportsمصطلحات موضوعية: Cirrhosis, TNF, Decompensated cirrhosis, RC799-869, cPGES, cytosolic PGE synthase, HPGD, 15-hydroxyprostaglandin dehydrogenase, Gastroenterology, Liver disease, MDMs, monocyte-derived macrophages, Microsomal PGE synthase 1, Ascites, LC-MS/MS, liquid chromatography-tandem mass spectrometry, CM, classical monocytes, Immunology and Allergy, MFI, mean fluorescence intensity, TNFα, tumour necrosis factor alpha, Whole blood, TIPS, transjugular intrahepatic portosystemic shunt insertion, EIA, enzyme immune assay, HLA DR, human leukocyte antigen – DR isotype, Diseases of the digestive system. Gastroenterology, Jaundice, sCD14, soluble CD14, medicine.anatomical_structure, CRP, C-reactive protein, LPS, lipopolysaccharide, lipids (amino acids, peptides, and proteins), medicine.symptom, Research Article, HVs, healthy volunteers, medicine.medical_specialty, LPS, CAID, cirrhosis-associated immune dysfunction, NASH, non-alcoholic steatohepatitis, mPGES1, microsomal PGE synthase 1, Cyclo-oxygenase 1, White blood cell, Internal medicine, PGE2, prostaglandin E2, Internal Medicine, medicine, Decompensation, FACS, polychromatic flow cytometric analysis, Hepatology, business.industry, Monocyte, HLA-DR, OPD, patients with refractory ascites attending hospital outpatient department for day case paracentesis, DSS, downstream synthases, medicine.disease, AD, acute decompensation, IL6, COX, cyclooxygenase, ACLF, acute-on-chronic liver failure, qPCR, quantitative PCR, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3389d2aeb9a6d0bb948f1425e23e31fcTest
https://doi.org/10.1016/j.jhepr.2021.100332Test