المؤلفون: Christophe Casteleyn, Benedicte Y. De Winter, Sven Francque, Luisa Vonghia, Denise van der Graaff, Isabel Pintelon, Joris G. De Man, Jean-Pierre Timmermans, Wilhelmus J. Kwanten, Shivani Chotkoe

المصدر: JHEP Reports
JHEP Reports, Vol 4, Iss 2, Pp 100412-(2022)

مصطلحات موضوعية: Portal venous pressure, thromboxane A2, RC799-869, AST, aspartate aminotransferase, Pharmacology, angiotensin II, Mx, methoxamine, Immunology and Allergy, ET, endothelin, TBW, total body weight, PP, portal pressure, IHVR, intrahepatic vascular resistance, Fatty liver, Gastroenterology, HFHFD, high-fat high-fructose diet, portal hypertension, Diseases of the digestive system. Gastroenterology, ARB, angiotensin receptor blocker, medicine.anatomical_structure, Valsartan, endothelin-1, medicine.drug, Research Article, NAFLD, non-alcoholic fatty liver disease, ATII, angiotensin II, NASH, non-alcoholic steatohepatitis, transhepatic pressure gradient, ALT, alanine aminotransferase, ZFR, Zucker fatty rats, Internal Medicine, medicine, TXAS, thromboxane synthase, SEM, scanning electron microscopy, PR, pulse rate, TEM, transmission electron microscopy, MCD, methionine-choline deficient diet, NO, nitric oxide, Hepatology, business.industry, non-alcoholic fatty liver disease, TxA2, thromboxane A2, medicine.disease, Angiotensin II, Bosentan, COX, cyclooxygenase, Jak2, Janus-kinase-2, Vascular resistance, Human medicine, Steatosis, Steatohepatitis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d7ccc5a41f528c2d7c72daa5110765Test
http://europepmc.org/articles/PMC8749167Test

المؤلفون: Elizabeth M. Brunt, Yan Xie, Nicholas O. Davidson, Saeed Soleyman-Jahi, Elizabeth P. Newberry, Samuel Ballentine, Elizabeth A. Molitor

المصدر: Journal of Lipid Research
Journal of Lipid Research, Vol 62, Iss, Pp 100123-(2021)

مصطلحات موضوعية: Male, antioxidant, microsomal triglyceride transfer protein, medicine.disease_cause, Biochemistry, Microsomal triglyceride transfer protein, Mice, Endocrinology, Methionine, Fibrosis, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, Chylomicrons, apolipoprotein B, oxidative stress, NF-κB, nuclear factor kappa B, Mice, Knockout, biology, TG, triglyceride, Chemistry, Choline Deficiency, Intestines, Chylomicron assembly, Lipogenesis, JNK, c-Jun N-terminal kinase, MCD, methionine/choline-deficient diet, TBARS, thiobarbituric acid reactive substance, Female, medicine.symptom, NASH, nonalcoholic steatohepatitis, TAM, tamoxifen, Research Article, medicine.medical_specialty, lipid absorption, Inflammation, Mice, Transgenic, Cer, ceramide, QD415-436, DNL, de novo lipogenesis, Mttp-IKO, microsomal triglyceride transfer protein knockout mice, Internal medicine, ALT, alanine aminotransferase, medicine, Animals, intestine, intestinal permeability, hepatic lipogenesis, fibrosis, Cell Biology, medicine.disease, SCD, steroyl CoA desaturase, Diet, Fatty Liver, lipoproteins, HFFC, high-fat, high-fructose, high-cholesterol diet, QC, quality control, biology.protein, NAFLD, nonalcoholic fatty liver disease, Steatosis, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b446d536c668b8da034c578efbbcbd05Test
https://pubmed.ncbi.nlm.nih.gov/34563519Test

المؤلفون: Takayoshi Suganami, Shuji Terai, Shunsuke Nojiri, Masahiro Ogawa, Tomoaki Yoshida, Atsunori Tsuchiya, Suguru Takeuchi, Takayuki Watanabe, Yoshihiro Ogawa, Masaaki Takamura, Michiko Itoh

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 14, Iss, Pp 252-261 (2020)

مصطلحات موضوعية: 0301 basic medicine, NAFLD, non-alcoholic fatty liver disease, Cirrhosis, MC4R, melanocortin-4 receptor-deficient, Lipopolysaccharide, ALT, alanine transaminase, NASH, non-alcoholic steatohepatitis, Biomedical Engineering, Adipose tissue, MSC, mesenchymal stem cell, Small extracellular vesicles, Pharmacology, hCLS, hepatic crown-like structure, Biomaterials, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, MCD, methionine-choline-deficient diet, Fibrosis, sEV, small extracellular vesicle, medicine, lcsh:QH573-671, Receptor, Non-alcoholic steatohepatitis, lcsh:R5-920, WD, Western diet, biology, business.industry, lcsh:Cytology, ND, normal diet, Mesenchymal stem cell, medicine.disease, 030104 developmental biology, chemistry, Alanine transaminase, biology.protein, Mesenchymal stem cells, Original Article, Steatohepatitis, business, lcsh:Medicine (General), HCC, hepatocellular carcinoma, T-bil, total bilirubin, T-cho, total cholesterol, 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c605b87d1574bec9c086c0f3c9517bTest
https://pubmed.ncbi.nlm.nih.gov/32455155Test

المؤلفون: Francisco Javier Cubero

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 545-546 (2020)

مصطلحات موضوعية: Oncology, Bemcentinib (BGB324), ADAM17, a disintegrin and metalloproteinase 17, MPO, myeloperoxidase, GAS6/TAM Signaling, Non-alcoholic Fatty Liver Disease, Medicine, MMP9, matrix metalloproteinase-9, Original Research, TNF, tumor necrosis factor, NAS, NAFLD activity score, Gastroenterology, ELISA, enzyme-linked immunosorbent assay, MCP-1, monocyte chemoattractant protein-1, sMERTK, soluble MERTK, HSC, hepatic stellate cell, mRNA, messenger RNA, ECM, extracellular matrix, Disease Progression, Liver Fibrosis, LPS, lipopolysaccharide, NASH, nonalcoholic steatohepatitis, Signal Transduction, medicine.medical_specialty, sAXL, soluble AXL, MEDLINE, PBS, phosphate-buffered saline, TAM, Tyro3-Axl-Mertk, HFD, high-fat choline-deficient methionine-restricted diet, cDNA, complementary DNA, PA, palmitic acid, MCD, methionine-choline-deficient diet, Internal medicine, Hepatic Stellate Cells, Humans, KC, Kupffer cell, lcsh:RC799-869, KO, knockout, Hepatology, business.industry, Disease progression, nutritional and metabolic diseases, GAS6, Growth arrest-specific gene 6, WT, wild-type, IL, interleukin, ADAM10, a disintegrin and metalloproteinase 10, H&E, hematoxylin and eosin, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease, business, HCC, hepatocellular carcinoma, Value (mathematics), PMH, primary mouse hepatocyte, Liver Inflammation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4447636c8bfbf18ac86d901acecbc4eTest
https://pubmed.ncbi.nlm.nih.gov/31689560Test

المؤلفون: Amalia Gastaldelli, Stefano Gatti, Miriam Longo, Stefano Romeo, Melania Gaggini, Paola Dongiovanni, Sara Badiali, Nicholas O. Davidson, Anna Ludovica Fracanzani, Guido Baselli, Serena Pelusi, Raffaela Rametta, Marica Meroni, Fabrizia Carli, Luca Valenti, Marco Maggioni

المصدر: EBioMedicine
EBioMedicine, Vol 52, Iss, Pp-(2020)

مصطلحات موضوعية: Research paper, TGFβ, Transforming Growth Factor Beta, Intracellular Space, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, hHEPS, Human Hepatocytes, Mice, 0302 clinical medicine, LPIAT1, DAG, Diacylglycerol, i.p., Intraperitoneal, media_common, Fatty Acids, General Medicine, 3. Good health, 030220 oncology & carcinogenesis, HOMA-IR, homeostasis Model Assessment of Insulin Resistance, MPO, morpholino, lcsh:Medicine (General), medicine.medical_specialty, PE, Phosphatidyl-Ethanolamine, Nash, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, TNFα, tumor Necrosis Factor Alpha, LDL, Low Density Lipoproteins, Hyperinsulinism, NAFLD, SD, Standard Diet, media_common.cataloged_instance, Humans, CPT1, Carnitine Palmitoyltransferase I, Phosphatidylinositol, Gene Silencing, European union, VLDL, Very Low Density Lipoprotein, lcsh:R, hHSC, Human Hepatic Stellate Cells, medicine.disease, Lipid Metabolism, OA, Oleic Acid, CI, Confidence Interval, Mboat7, Membrane bound O-acyltransferase domain containing 7, MCD, methionine choline deficient diet, 030104 developmental biology, Endocrinology, chemistry, CDP, Cytidine-Diphosphate, FOXO1, Forkhead Box protein O1, NAFLD, nonalcoholic fatty liver disease, Steatohepatitis, BMI, Body Mass Index, CL, Cardiolipin, Acyltransferases, 0301 basic medicine, Alcoholic liver disease, CXCL10, C-X-C Motif Chemokine 10, lcsh:Medicine, chemistry.chemical_compound, Non-alcoholic Fatty Liver Disease, IFG, Impaired Fasting Glucose, APOB, Apolipoprotein B, Nonalcoholic fatty liver disease, PIP, Phosphatidyl-Inositol-Phosphate, qRT-PCR, quantitative Real Time Polymerase Chain Reaction, Mice, Knockout, lcsh:R5-920, ORO, Oil Red O Staining, PI, Phosphatidylinositol, Fatty liver, TM6SF2, Transmembrane 6 Superfamily Member 2, Phospholipid, TAG, Triglycerides, NASH, Nonalcoholic Steatohepatitis, Lipogenesis, LPA, Lyso-Phosphatidic Acid, Signal Transduction, PS, Phosphatidyl-Serine, PA, Palmitic Acid, ALD, alcoholic liver disease, PC, Phosphatidylcholine, i.v., Intravenous, FATP1, Fatty Acid Transport Protein 1, Models, Biological, Internal medicine, medicine, Animals, PPARα, Peroxisome Proliferator-Activated Receptor alpha, Obesity, G3P, Glyceraldehyde-3-Phosphate, SREBP1c, Sterol Regulatory Element-Binding Protein 1, HDL, High Density Lipoproteins, business.industry, PI3K, Phosphatidylinositol 3 Kinase, Membrane Proteins, NHEJ, Non-Homologues End Joining, PNPLA3, Patatin-like Phospholipase Domain-containing-3, MTTP, Microsomal Triglyceride Transfer Protein, LPIAT1, Lysophosphatidylinositol Acyltransferase 1, TMC4, Transmembrane Channel-Like 4, Disease Models, Animal, Gene Expression Regulation, Hepatocytes, FOXA2, Forkhead Box A2, mTOR, mammalian target of Rapamycin, Steatosis, Insulin Resistance, business, PG, Phosphatidyl-Glycerol, FABP1, Fatty Acid-Binding Protein 1, FAS, Fatty Acid Synthase, T2DM, Type 2 Diabetes Mellitus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2796cd352ac1c041a84c02697c2c55d9Test
https://pubmed.ncbi.nlm.nih.gov/32058943Test

المؤلفون: Miguel López, Rubén Nogueiras, Xabier Buqué, Maria J. Gonzalez-Rellan, Daniel Beiroa, Patricia Aspichueta, Uxia Fernandez, Begoña Porteiro, Rosalía Gallego, Carlos Dieguez, Guadalupe Sabio, Marcos F. Fondevila, Johan Fernø, Ana Senra, Alfonso Mora

المساهمون: Ministerio de Economía y Competitividad (España), Xunta de Galicia (España), Heise Vest RHF, Comunidad de Madrid (España), Basque Government (España), Fundación AstraZeneca, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Unión Europea. Comisión Europea, Centro de Investigación Biomedica en Red - CIBER

المصدر: Molecular Metabolism, Vol 8, Iss, Pp 132-143 (2018)
Molecular Metabolism
Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: 0301 basic medicine, pIRE, Inositol-requiring enzyme 1 α, pJNK, phospho c-Jun N-terminal kinase, ACC, acetyl-CoA carboxylase, AST, aspartate aminotransferase, XBP1s, X-box binding protein 1, Abcd1, ATP binding cassette subfamily D member 1, Pharmacology, ER stress, endoplasmic reticulum stress, NFκβ, nuclear factor kappa b, FA, free fatty acid, Mice, Liver disease, UPR, unfolded protein response, 0302 clinical medicine, HFD, high fat diet, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, DG, diacylglycerol, Topoisomerase II Inhibitors, IL6, initerleukin 6, Beta oxidation, Acadm, acyl-CoA deshydrogenase, medium chain, GFP, green fluorescent protein, IL10, interleukin 10, Acox, acyl-CoA oxidase 1, TG, triglyceride, Ad, adenovirus, Hep G2 Cells, Acadl, acyl-CoA deshydrogenase, long-chain, i.p., intraperitoneal, FAS, fatty acid synthase, 3. Good health, Liver, Pparα, peroxisome proliferator activated receptor alpha, JNK, c-Jun N-terminal kinase, Lipogenesis, DOX, Doxorubicin, DN, dominant negative, Original Article, ApoB, apolipoprotein b, Quer, quercetin, NAFLD, non-alcoholic fatty liver disease, lcsh:Internal medicine, ASM, acid-soluble metabolites, NASH, non-alcoholic steatohepatitis, TNFα, tumor necrosis factor alpha, GAPDH, glyceraldehyde-3-phosphate deshydrogenase, AUC, area under curve, Diet, High-Fat, Cell Line, SPF, specific pathogen free room, 03 medical and health sciences, GTT, glucose test tolerance, ALT, alanine aminotransferase, AAV8, adeno-associated virus serotype 8, medicine, Animals, Humans, Obesity, EC, sterified cholesterol, lcsh:RC31-1245, Molecular Biology, MCD, methionine-choline deficient diet, CHOP, C/EBP-homologous protein, Inflammation, business.industry, OA, oleic acid, Lipid metabolism, DIO, diet-induced obesity, Cell Biology, Lipid Metabolism, medicine.disease, CDHFD, choline-deficient high fat diet, Mice, Inbred C57BL, 030104 developmental biology, Doxorubicin, pACC, phospho acetyl-CoA carboxylase, Hepatic stellate cell, BSA, bovine serum albumin, Tumor Suppressor Protein p53, Steatohepatitis, Steatosis, business, Fatp2, solute carrier family 27 (fatty acid transporter) member 2, IL1β, interleukin 1beta, 030217 neurology & neurosurgery, ITT, insulin test tolerance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7642e1971aebb46c881386960e7affTest
http://www.sciencedirect.com/science/article/pii/S2212877817310116Test