المؤلفون: Jorge Quarleri, M. Victoria Delpino

المصدر: Cytokine & Growth Factor Reviews

مصطلحات موضوعية: 0301 basic medicine, viruses, Endocrinology, Diabetes and Metabolism, IFNAR, type I IFN receptor, IKKε, IκB kinase-ε, Disease, LGP2, laboratory of genetics and physiology-2, IRF, IFN regulatory factor, medicine.disease_cause, IκB, inhibitor of nuclear factor κB, TLRs, Toll-like receptors, Interferon Lambda, IFITM, interferon-induced transmembrane proteins, AAV, adeno-associated virus, 0302 clinical medicine, PRRs, pattern recognition receptors, Interferon, Immunology and Allergy, IGFBP3, insulin-like growth factor-binding protein 3, TRAF3, tumor necrosis factor receptor-associated factor 3, SOCS, suppressor of cytokine signaling proteins, MOI, multiplicity of infection, human coronavirus, Coronavirus, TBK1, TANK binding kinase 1, Effector, KPNA2, karyopherin-α2, HCoV, human coronaviruses, MERS-CoV, Middle East respiratory syndrome coronavirus, interferon, STATs, signal transducer and activator of transcription, dsRNA, double stranded RNA, 030220 oncology & carcinogenesis, Host-Pathogen Interactions, Interferon Type I, MAVS, mitochondrial antiviral signaling protein, inborn errors, medicine.drug, MDA5, melanoma differentiation-associated gene 5, S, spike, JAK1, Janus kinase 1, Tyk2, Jak tyrosine kinases tyrosine kinase 2, Immunology, NPC, nuclear pore complex, E, envelope, ISGs, interferon-stimulated genes, ORFs, open reading frames, Biology, ACE2, angiotensin-converting enzyme 2, Antiviral Agents, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Article, General Biochemistry, Genetics and Molecular Biology, Virus, scRNA-seq, single-cell RNA-sequencing, Viral Proteins, 03 medical and health sciences, Immune system, PAMPs, pathogen-associated molecular patterns, M, membrane, medicine, Animals, Humans, Genetic Predisposition to Disease, IFN, interferon, SARS, severe acute respiratory syndrome, Pandemics, KLF-5, Krüpple-like factor 5, immune evasion, NF-κB, transcription factors nuclear factor-κB, Innate immune system, SARS-CoV-2, Genetic Diseases, Inborn, Autoantibody, COVID-19, ISRE, IFN-stimulated response element, HIF1α, hypoxia-inducible factor-1α, Immunity, Innate, ISGF3, IFN-stimulated growth factor 3, RIG-I, retinoic acid-inducible gene 1, 030104 developmental biology, TBK1, TANK-binding kinase 1, TMPRSS2, transmembrane serine protease 2, Interferons, TANK, TRAF family member-associated NF-κB activator, IFNLR, IFN-λ receptor, N, nucleocapsid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0ed2f72291aa86d6f23c42f116bc46Test
https://doi.org/10.1016/j.cytogfr.2021.01.003Test

المؤلفون: Ioanna-Evdokia Galani, Evangelos Andreakos

المصدر: Seminars in Immunology

مصطلحات موضوعية: SARS, Severe acute respiratory syndrome, MDA5, Melanoma-differentiated gene 5, PRR, Pattern-recognition receptor, Disease, Review, Adaptive Immunity, LY6E, Lymphocyte antigen 6 complex, locus E, pDC, plasmacytoid dendritic cell, KPNA2, Karyopherin α2, Pandemic, Immunology and Allergy, Medicine, CoV, Coronavirus, IL, Interleukin, TNF-α, Tumor necrosis factor alpha, CRS, Cytokine release syndrome, Pathogen, Infectivity, COVID-19, Coronavirus disease 2019, TBK1, TANK binding kinase 1, Acquired immune system, ISG, Interferon-stimulated gene, IFN, Interferon, STAT, signal transducer and activator of transcription, antiviral innate immunity, NF-κB, Nuclear factorκB, JAK, Janus kinase, N/L, Neutrophil to lymphocyte, TLR, Toll-like receptor, TMPRSS2, Transmembrane serine protease 2, Immunology, Antiviral Agents, Virus, RLR, RIG-I like receptor, Immunity, Humans, ARDS, acute respiratory distress syndrome, ComputingMethodologies_COMPUTERGRAPHICS, Innate immune system, business.industry, SARS-CoV-2, MERS, Middle East respiratory syndrome, NSP, Non-structural protein, COVID-19, biochemical phenomena, metabolism, and nutrition, MAVS, Mitochondrial antiviral-signaling protein, Immunity, Innate, RIG, Retinoic acid-inducible gene 1, S, Spike, ORF, Open reading frame, OAS, Oligoadenylate synthetase, Interferons, ACE-2, Angiotensin-converting enzyme 2, business, IRF, Interferon regulatory factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b54b4adb408a46b7343cb6a38b77d2Test
http://europepmc.org/articles/PMC8576141Test

المؤلفون: Wen Li, Hiroshi Kurihara, Chang Yan, Zhuo Luo, Rong-Rong He, Yi-Fang Li, Robert Dallmann, Xue Li

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 383-398 (2020)

مصطلحات موضوعية: TRKA, tropomyosin receptor kinase A, CTCF, CCCTC-binding factor, GREs, GR response elements, viruses, Cell, GRs, glucocorticoid receptors, SGKs, serum and glucocorticoid-regulated protein kinases, Stimulation, Review, PTMs, post-translational modifications, Herpes simplex virus type 1, medicine.disease_cause, 0302 clinical medicine, NK cells, natural killer cells, REST, RE1-silencing transcription factor, H3K9, histone H3 on lysines 9, sncRNAs, small non-coding RNAs, HSV-1, herpes simplex virus type 1, General Pharmacology, Toxicology and Pharmaceutics, ICP, infected cell polypeptide, MOI, multiplicity of infection, 0303 health sciences, PDK1, pyruvate dehydrogenase lipoamide kinase isozyme 1, TRIM14, tripartite motif-containing 14, PRRs, pattern-recognition receptors, OCT-1, octamer binding protein 1, Reactivation, HSV-1, RANKL, receptor activator of NF-κB ligands, T3, thyroid hormone, humanities, medicine.anatomical_structure, 4E-BP, eIF4E-binding protein, CPE, cytopathic effect, 030220 oncology & carcinogenesis, Latency, HPK, herpetic simplex keratitis, AD, Alzheimer's disease, DCs, dendritic cells, TCM, traditional Chinese medicine, TRM, tissue resident memory T cells, Recurrent infections, HPT axis, hypothalamic–pituitary–thyroid axis, LAT, latency-associated transcripts, SIRT1, sirtuin 1, AMPK, AMP-dependent kinase, NGF, nerve growth factor, TK, thymidine kinase, DEX, dexamethasone, HPA axis, hypothalamo–pituitary–adrenal axis, mTOR, mammalian target of rapamycin, MAVS, mitochondrial antiviral-signaling protein, ORFs, open reading frames, Biology, Stress, CNS, central nervous system, Inhibitory postsynaptic potential, AKT, protein kinase B, HCF-1, host cell factor 1, Virus, 03 medical and health sciences, ROS, reactive oxygen species, CORT, corticosterone, PRC1, protein regulator of cytokinesis 1, PAMPs, pathogen-associated molecular patterns, medicine, Latency (engineering), 030304 developmental biology, Balance (ability), PML, promyelocytic leukemia protein, IRF3, interferon regulatory factor 3, lcsh:RM1-950, ND10, nuclear domains 10, LSD1, lysine-specific demethylase 1, CTL, cytotoxic T lymphocyte, HDACs, histone deacetylases, LRF, Luman/CREB3 recruitment factor, CoREST, REST corepressor 1, lcsh:Therapeutics. Pharmacology, cGAS, cyclic GMP-AMP synthase, Herpes simplex virus, TG, trigeminal ganglia, Susceptibility, PI3K, phosphoinositide 3-kinases, DAMPs, damage-associated molecular patterns, Immunology, PNS, peripheral nervous system, BCL-2, B-cell lymphoma 2, KLF15, Krüppel-like transcription factor 15

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e8bd4a9163466778ab2c0a48ebad5dTest
https://doi.org/10.1016/j.apsb.2019.06.005Test

المؤلفون: Richard L. Gallo, Tatsuya Dokoshi, Alan M. O’Neill, Elizabeth Wei Chia Luo, Nikhil Nitin Kulkarni, Gerard C. L. Wong

المصدر: The Journal of Biological Chemistry
The Journal of biological chemistry, vol 297, iss 1

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, medicine.medical_treatment, Inbred C57BL, Biochemistry, Medical and Health Sciences, Cathelicidin, Mice, Double-Stranded, antimicrobial peptides, SR, scavenger receptor, Receptors, cathelicidin, Innate, Receptor, GAS, group A Streptococcus, Receptors, Scavenger, Alanine, LDH, lactate dehydrogenase, Chemistry, LL-37, 37-amino acid peptide, UCSD, University of California, San Diego, SAXS, small-angle X-ray scattering, interferon, Alanine scanning, Biological Sciences, Cell biology, IL-6, interleukin 6, Infectious Diseases, LL-34, 34-amino acid peptide, Interferon Type I, qRT-PCR, quantitative RT-PCR, Female, NHEK, normal human epidermal keratinocyte, Transcription, RIGI, retinoic acid–inducible gene I, Research Article, Protein Binding, Signal Transduction, Biochemistry & Molecular Biology, skin, HDMEC, human dermal microvascular endothelial cell, MIC, minimum inhibitory concentration, Antimicrobial peptides, I20P, proline at isoleucine position 20, IRF7, interferon regulatory factor 7, Biophysical Phenomena, Scavenger, MAVS, mitochondrial antiviral signaling, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, Genetic, Cathelicidins, GO, Gene Ontology, medicine, Genetics, Animals, Humans, Amino Acid Sequence, Molecular Biology, RNA, Double-Stranded, Inflammation, Innate immune system, 030102 biochemistry & molecular biology, Cell Membrane, Immunity, RNA, Cell Biology, cytokines, Immunity, Innate, Toll-Like Receptor 3, Mice, Inbred C57BL, 030104 developmental biology, Emerging Infectious Diseases, Gene Expression Regulation, Chemical Sciences, TBK1, TANK-binding kinase 1, Mutation, Nucleic acid, Antimicrobial Cationic Peptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7653124affc7f3c4f58a75aed7ae4eb7Test
http://europepmc.org/articles/PMC8214221Test

المؤلفون: Shue-Fen Luo, Jenn-Haung Lai, Ling-Jun Ho

المصدر: Biochemical Pharmacology

مصطلحات موضوعية: 0301 basic medicine, PRR, pattern recognition receptor, DENV, dengue virus, cGAS, cyclic GMP–AMP synthase, Mitochondrion, Mitochondrial Dynamics, Biochemistry, NLR, NOD-like receptor, Mfn, mitofusin, Mitophagy, TRAF, TNF receptor-associated factor, RIPK2, cytosolic receptor interacting serine/threonine kinase 2, SARS-CoV, severe acute respiratory syndrome-coronavirus, NLRP3, NOD-, LRR- and pyrin domain-containing 3, Mitochondria, Virus, Cell biology, CLR, C-type lectin receptor, TNFα, tumor necrosis factor α, OPA1, optic atrophy 1, Virus Diseases, CARD, caspase activation and recruitment domain, HCV, hepatitis C virus, MAVS, mitochondrial antiviral signaling protein, HPIV3, human parainfluenza virus type 3, PAMP, pathogen-associated molecular pattern, DAMP, danger-associated molecular pattern, Mitochondrial DNA, JEV, Japanese encephalitis virus, PINK1, phosphatase and tensin homolog (PTEN)-induced kinase 1, STING, stimulator of interferon genes, Biology, Antiviral Agents, Article, 03 medical and health sciences, NF-κB, nuclear factor-kappaB, ROS, reactive oxygen species, Immune system, ORF, open reading frame, Downregulation and upregulation, Immunity, KSHV, kaposi’s sarcoma-associated herpesvirus, Animals, Humans, IFN, interferon, TLR, toll-like receptor, ComputingMethodologies_COMPUTERGRAPHICS, Pharmacology, Immunity, Innate, RLR, retinoic acid-inducible gene 1-like receptor, mtDNA, mitochondrial DNA, vMIA, viral mitochondrion-localized inhibitor of apoptosis, Immune, RIG-I, retinoic acid-inducible gene 1, Drp 1, dynamin-related protein 1, 030104 developmental biology, Apoptosis, CO, cytochrome C oxidase, RSV, respiratory syncytial virus, Therapy, MAPK, mitogen-activated protein kinase, IRF, interferon regulatory factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddc4d9d42601f3845bf94ae189aa4cbTest
https://doi.org/10.1016/j.bcp.2018.08.044Test

المؤلفون: Myung Hee Kim, Sunghoon Kim, Eun-Young Lee

المصدر: Biochemical Pharmacology

مصطلحات موضوعية: 0301 basic medicine, PTM, post-translational modification, Antiviral immunity, TNF-α, tumor necrosis factor-α, Biochemistry, Human health, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, Antibiotics, RIG-I, retinoic acid-inducible gene-I, MEK, MAPK kinase kinase, Multi-tRNA synthetase complex, ERK, extracellular-related kinase, ARS, aminoacyl-tRNA synthetase, BMDM, bone marrow-derived macrophage, Anti-Bacterial Agents, HIV, human immunodeficiency virus, HCV, hepatitis C virus, 030220 oncology & carcinogenesis, MAVS, mitochondrial antiviral signaling protein, CRP, C-reactive protein, LPS, lipopolysaccharide, EMAPII, endothelial monocyte-activating polypeptide II, Infection, Medical science, TH1, T-helper type 1, Signal Transduction, PBMC, peripheral blood mononuclear cell, TLS, tRNA-like structure, Cell signaling, IL-1β, interleukin-1β, ITCH, E3 ubiquitin-protein ligase Itchy homolog, IP-10, interferon-inducible protein 10, AA-AMP, aminoacyl-adenylate, MITF, microphthalmia-associated transcription factor, IFN-α, interferon-α, Microbial Sensitivity Tests, Computational biology, Biology, Antiviral Agents, Communicable Diseases, Article, Amino Acyl-tRNA Synthetases, 03 medical and health sciences, Immunity, TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, BMDC, bone marrow-derived dendritic cell, Animals, Humans, IFN, interferon, TCID50, a median tissue culture infective dose, TLR, toll-like receptor, ComputingMethodologies_COMPUTERGRAPHICS, eEF1A, eukaryotic elongation factor 1 alpha, AIMP, ARS-interacting multifunctional protein, Pharmacology, Aminoacyl tRNA synthetase, PCBP2, poly(rC)-binding protein 2, Oas, 2′-5′-oligoadenylate synthase, WT, wild-type, MDA5, melanoma differentiation-associated protein 5, HMGB1, high mobility group box 1, 030104 developmental biology, chemistry, TGF-β, tumor growth factor-β, Protein Biosynthesis, Aminoacyl-tRNA synthetase, MSC, multi-tRNA synthetase complex, GAIT, IFN-γ-activated inhibition of translation, MAPK, mitogen-activated protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb23dff1f01e90e977d9a7c03e1669f1Test
https://doi.org/10.1016/j.bcp.2018.06.009Test

المؤلفون: Timothy K. Soh, Luca Mascheroni, Vivienne Connor, Katharina M. Scherer, James D. Manton, Clemens F. Kaminski, Colin M. Crump

المساهمون: Scherer, Katharina [0000-0002-2042-5407], Crump, Colin [0000-0001-9918-9998], Kaminski, Clemens [0000-0002-5194-0962], Apollo - University of Cambridge Repository

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, organelle, viruses, Golgi Apparatus, PFU, plaque forming unit, Herpesvirus 1, Human, medicine.disease_cause, Virus Replication, Biochemistry, ICP0, infected cell protein, FOV, field of view, Multiplicity of infection, TGN46, trans-Golgi network protein 46, Genes, Reporter, Chlorocebus aethiops, gM, glycoprotein M, TEMED, tetramethylethylenediamine, eYFP, enhanced yellow fluorescent protein, mIFP, monomeric infrared fluorescent protein, SIM, structured illumination microscopy, gC, glycoprotein C, MOI, multiplicity of infection, Plaque-forming unit, cytoskeleton, APS, ammonium persulfate, Cell biology, HFF, human foreskin fibroblast, AC, assembly compartment, RIG-1, retinoic acid-inducible gene I, symbols, microscopy, DMEM, Dulbecco's modified eagle's medium, fluorescence, Single-Cell Analysis, host–pathogen interaction, Research Article, HSV-1, herpes simplex virus-1, microscopic imaging, Host–pathogen interaction, Biology, MAVS, mitochondrial antiviral-signaling protein, Virus, 03 medical and health sciences, symbols.namesake, Capsid, Spatio-Temporal Analysis, herpesvirus, FBS, fetal bovine serum, PBS, phosphate buffered saline, medicine, MTOC, microtubule organizing center, Animals, Humans, hpi, hours post infection, Molecular Biology, Vero Cells, RLR, RIG-1-like receptors, HCMV, human cytomegalovirus, SiR, silicon rhodamine, 030102 biochemistry & molecular biology, TGN, trans-Golgi network, Virus Assembly, Cell Biology, Golgi apparatus, 030104 developmental biology, Herpes simplex virus, Viral replication, Microscopy, Fluorescence, BAC, bacterial artificial chromosome, TOM20, translocase of the outer membrane, BSA, bovine serum albumin, EEA1, early endosome antigen 1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80cec3952cdc85557f3c8aa73279a507Test
http://europepmc.org/articles/PMC7948757Test

المؤلفون: Vik Ven Eng, Madeleine A. Wemyss, Jaclyn S. Pearson

المصدر: Seminars in Cell & Developmental Biology

مصطلحات موضوعية: NSA, necrosulfonamide, T4SS, type IV secretion system, RHIM, RIP homotypic interaction motif, ERK, extracellular signal-regulated kinases, MDP, muramyl dipeptide, TNF, tumour necrosis factor, RIP kinase, 0302 clinical medicine, UPR, unfolded protein response, RIG-I, cytosolic retinoic acid-inducible gene I, T3SS, type III secretion system, TGFβ, transforming growth factor beta, AEC, airway epithelial cell, MCMV, murine cytomegalovirus, NP, nucleoprotein, ZBP1, Z-DNA binding protein, Kgp, lysine-specific protease gingipain, COTV, Cotia poxvirus, COVID-19, coronavirus disease 2019, XIAP, X-linked inhibitor of apoptosis protein, ALRs, AIM2-like receptors, KD, kinase domain, Kinase, Th1, T helper 1, BMDMs, bone marrow-derived macrophages, HFMD, hand foot and mouth disease, BclxL, Bcl-extra large, TRAM, translocating chain-associated membrane protein, dsRNA, double stranded RNA, LMP1, latent membrane protein, Cell biology, Intracellular signal transduction, CARD, caspase activation and recruitment domain, SDH, succinate dehydrogenase, TRPM7, transient receptor potential cation channel subfamily M member 7, IKK, IĸB kinase, MAVS, mitochondrial antiviral signaling proteins, NK, natural killer, TRIF, TIR-domain-containing adapter-inducing interferon-β, ISGF3, IFN-stimulated gene factor 3, Cell signaling, AIM2, absent in melanoma 2, PD, Parkinson disease, Yop, Yersinia outer protein, JEV, Japanese encephalitis virus, Poly(I:C), polyinosinic:polycytidylic acid, Article, PKR, protein kinase R, vIRA, viral inhibitor of RIP activation, RIPK2, 03 medical and health sciences, RIPK1, BAV, BeAn 58058 poxvirus, NLRs, nucleotide-binding domain–like receptors, ORF, open reading frame, IAV, influenza A virus, MyD88, myeloid differentiation factor 88, CD, Crohn’s disease, Humans, SARS, severe acute respiratory syndrome, DAMPs, danger-associated molecular patterns, GSDMD, gasdermin D, TLR, toll-like receptor, UL45/UL48, human CMV envelope protein 45/48, RR, ribonucleotide reductase, OMV, outer membrane vesicle, NO, nitric oxide, Pathogen-associated molecular pattern, TRAILR, TNF-related apoptosis-inducing ligand receptor, COR, C-terminal of Roc, DR, death receptor, GEF, guanidine exchange factor, IĸB, inhibitor of ĸB, WT, wild-type, Saporins, HMGB1, high mobility group box 1, IL, interleukin, MDA5, melanoma differentiation-associated protein 5, 030104 developmental biology, siRNA, small interfering RNA, TBK1, TANK-binding kinase 1, PFT, pore-forming toxins, ISGs, interferon stimulated genes, Cif, cycle inhibiting factor, RSV, respiratory syncytial virus, TRADD, TNFR1-associated death domain protein, Bacterial infection, PAMPs, pathogen associated molecular patterns, 030217 neurology & neurosurgery, Developmental Biology, 0301 basic medicine, NSP, non-structural protein, Bcl-2, B-cell lymphoma 2, CA6, coxsackievirus A6, DENV, dengue virus, E3L, vaccinia virus protein E3 long, TAK1, TGFβ-activated kinase 1, iE-DAP, Ɣ-d-glutamyl-mesodiaminopimelic acid, AP-1, activator protein 1, vICA, viral inhibitor of caspase-8 activation, ZIKV, Zika virus, HIV-1, human immunodeficiency virus type 1, PI3K, PI3 kinase, ATG16L1, autophagy-related 16-like 1, CVB, coxsackievirus B3, PRRs, pattern recognition receptors, SNPs (line 657) ssRNA, single-stranded RNA, MAPKs, mitogen-activated protein kinases, Pathogen, HSV, Herpes simplex virus, DAI, DNA-dependent activator of IRFs, EBV, Epstein-Barr virus, M45, murine CMV virion associated protein M45, PGN, bacterial peptidoglycan, DAP, diaminopimelic acid, UBE2N, ubiquitin-conjugating enzyme E2N, ID, intermediate domain, NleB, non-LEE encoded effector protein B, c-FLIP, cellular FLICE inhibitory protein, DRP1, dynamin-related protein 1, vMLKL, viral MLKL-like proteins, IRG1, immunoresponsive gene 1, LRR, leucine-rich repeat, NF-ĸB, nuclear factor-ĸB, TNFR1, TNF receptor type 1, WNV, West Nile virus, HCV, hepatitis C virus, JNK, c-Jun N-terminal kinase, Host-Pathogen Interactions, LPS, lipopolysaccharide, Roc, Ras-of-complex, PVM, pneumonia virus of mice, NET, neutrophil extracellular traps, HAEC, human aortic endothelial cells, ASC, apoptosis-associated speck-like protein, NLRC4, NLR family CARD domain containing 4, SARS-3a, SARS-CoV ORF protein 3a, Cell death, VSV, vesicular stomatitis virus, PnCW, pneumococcal cell wall, RIPKs, receptor interacting protein kinases, Mtb, Mycobacterium tuberculosis, HBeAg, hepatitis B e antigen, Biology, CNS, central nervous system, cIAPs, cellular inhibitor of apoptosis proteins, ER, endoplasmic reticulum, IFI44L, IFN-induced protein 44-like, NOD, nucleotide-binding oligomerization domain, ROS, reactive oxygen species, DISCs, death-inducing signaling complexes, NoV, norovirus, 3Cpro, viral non-structural protein 3C, IFN, interferon, VV, vaccinia virus, PR, protease, TRAF, TNFR associated factors, Inflammation, CNF1, cytotoxic necrotising factor 1, HCMV, human cytomegalovirus, KO, knockout, NLRP3, NLR family pyrin domain containing 3, Nec-1, necrostatin-1, Autophagy, IRFs, IFN regulatory factors, Cell Biology, CMV, cytomegalovirus, MLKL, mixed-lineage kinase-domain like protein, HPV, human papilloma virus, NAIPs, NLR family apoptosis inhibitory proteins, HBV, hepatitis B virus, PI3P, phosphatidylinositol 3-phosphate, RDA, RIPK1-dependent apoptosis, Viral infection, MKKs, MAPK kinases, LUBAC, linear ubiquitin chain assembly complex, BVDV, bovine viral diarrhoea virus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628bb448c2d6de5b9d7755cdadd35794Test
http://europepmc.org/articles/PMC7448748Test

المؤلفون: Frank Loganzo, Aaron Y. Chang, Kesha M. Shah, Yu Jerry Zhou, Seng-Ryong Woo, Heather Wheeler, Paula M. Loria, Piotr W. Pobiarzyn, Pavel Tishchenko, Yue-Ming Wang, Sharanya Iyengar

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: RNA splicing, THP-1 Cells, IFN-I, type I interferon, Biochemistry, Mice, hpRNA, hairpin RNA, RNA Precursors, cytokine, MDA5, melanoma differentiation–associated protein 5, anticancer drug, Receptors, Immunologic, innate immunity, HDR, homology-directed repair, Chemistry, RIG-I, interferon, Cell biology, RIG-I-like receptor, interferon regulatory factor, Stimulator of interferon genes, Interferon Type I, MAVS, mitochondrial antiviral signaling protein, DEAD Box Protein 58, RNA Splicing Factors, Research Article, Spliceosome, Plad B, pladienolide B, mRNA, sgRNA, single-guide RNA, Mutation, Missense, TNFα, tumor necrosis factor alpha, STING, stimulator of interferon genes, Proinflammatory cytokine, alternative splicing, cDNA, complementary DNA, HEK, human embryonic kidney, SF3B1, spliceosome splicing factor 3b subunit 1, Animals, Humans, Molecular Biology, IRF3, interferon regulatory factor 3, Cell Biology, Phosphoproteins, IL, interleukin, RIG-I, retinoic acid–inducible gene I, LU, light unit, NGS, next-generation sequencing, Amino Acid Substitution, A549 Cells, ISG54, interferon-stimulated gene 54, Spliceosomes, SEAP, secreted embryonic alkaline phosphatase, spliceosome, IRF3, Interferon regulatory factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0807c9654609f5efbfc7af1d5f8f788cTest
https://doi.org/10.1016/j.jbc.2021.101277Test

المؤلفون: Guy Ungerechts, Mathias F. Leber, Russell Barkley, John C. Bell, Serge Neault, Elise Jirovec, Aida Said

المصدر: Cytokine & Growth Factor Reviews

مصطلحات موضوعية: 0301 basic medicine, BiTE, bi-specific T-cell engager, viruses, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, OV, oncolytic virus, RT, radiotherapy, TIL, tumor infiltrating lymphocyte, 5-FUMP, 5-fluorouridine monophosphate, CPA, cyclophosphamide, combination therapy, 0302 clinical medicine, CHIK, chikungunya, Cancer immunotherapy, HADC, histone deacetylase, PNP, purine nucleoside phosphorylase, FMG, fusogenic membrane glycoprotein, Neoplasms, Immunology and Allergy, SCD, super cytosine deaminase, GA, geldanamycin, ICI, immune checkpoint inhibition, MOI, multiplicity of infection, H, hemagglutinin, Oncolytic Virotherapy, biology, Genetically modified virus, MCP, membrane cofactor protein, Ad, adenovirus, DCA, dichloroacetate, TME, tumor microenvironment, PD, programmed cell death, i.p., intraperitoneal, IDO, indoleamine 2,3-dioxygenase, Oncolytic Viruses, 030220 oncology & carcinogenesis, CCNU, lomustine, MAVS, mitochondrial antiviral signaling protein, Immunotherapy, virotherapy, GM-CSF, granulocyte-macrophage colony-stimulating factor, NK, natural killer, ATP, adenosine triphosphate, Combination therapy, PVRL4, poliovirus receptor-like 4, Immunology, CTLA-4, cytotoxic T-lymphocyte-associated protein 4, F, fusion, General Biochemistry, Genetics and Molecular Biology, Article, Measles virus, CDV, canine distemper virus, 03 medical and health sciences, medicine, Humans, IFN, interferon, SLAMF1, signaling lymphocytic activation molecule, family member 1, Virotherapy, SCID, severe combined immunodeficient, ComputingMethodologies_COMPUTERGRAPHICS, oncolytic virus, genetic engineering, TMZ, temozolomide, business.industry, i.t., intratumoral, MeV, measles virus, Cancer, scFv, single-chain variable fragment, biology.organism_classification, medicine.disease, Virology, Oncolytic virus, EGFR, epidermal growth factor receptor, IL, interleukin, FDA, U.S. Food and Drug Administration, 030104 developmental biology, NIS, sodium iodide symporter, EMA, European Medicines Agency, HSV, herpes simplex virus, CEA, carcinoembryonic antigen, business, HCC, hepatocellular carcinoma, IRF, interferon regulatory factor

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52eac8c05437b2e621246bdba847551eTest
https://pubmed.ncbi.nlm.nih.gov/32718830Test