نتائج البحث - "MAP2, microtubule-associated protein 2"

1

Umbilical artery tissue contains p75 neurotrophin receptor-positive pericyte-like cells that possess neurosphere formation capacity and neurogenic differentiation potential

المؤلفون: Narihito Nagoshi, Taro Matsumoto, Rina Fujii-Tezuka, Ichiro Morioka, Hideyuki Okano, Shori Takahashi, Hideo Mugishima, Mika Ishige-Wada

المصدر: Regenerative Therapy
Regenerative Therapy, Vol 16, Iss, Pp 1-11 (2021)

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), DMEM, Dulbecco's modified Eagle medium, MSCs, mesenchymal stem cells, WJ, Wharton's jelly, FGF-2, fibroblast growth factor-2, ASMA, α-smooth muscle actin, vWF, von Willebrand factor, PDGF, platelet-derived growth factor, 0302 clinical medicine, Immunophenotyping, βME, β-mercaptoethanol, DAPI, 4′,6-diamino-2-phenylindole, p75 neurotrophin receptor, UA, umbilical artery, CFU-F, colony-forming unit fibroblast, FSK, forskolin, EdU, 5-ethynyl-2′-deoxyuridine, UC, umbilical cord, Neural crest, EGFP, enhanced green fluorescent protein, Cell biology, medicine.anatomical_structure, NCSCs, neural crest-derived stem cells, CD146, Original Article, Pericyte, Neural crest stem cells, Stem cell, α-MEM, alpha-modified minimum essential medium, BDNF, bone-derived neurotrophic factor, PBS, phosphate-buffered saline, Biomedical Engineering, Neurosphere, Biology, p75NTR, p75 neurotrophin receptor, Biomaterials, MAP2, microtubule-associated protein 2, 03 medical and health sciences, R5-920, FBS, fetal bovine serum, medicine, CD90, NG2, neuron-glial antigen 2, Umbilical cord, EGF, epidermal growth factor, QH573-671, Mesenchymal stem cell, GFAP, glial fibrillary acidic protein, NF200, neurofilament 200, TBS, Tris-buffered saline, 030104 developmental biology, UV, umbilical vein, Mesenchymal stem cells, sense organs, Cytology, RA, all-trans-retinoic acid, 030217 neurology & neurosurgery, Developmental Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bca0eb0c096fcf86a7231acba5512cTest
https://doi.org/10.1016/j.reth.2020.12.002Test

2

Prolactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro Model

المؤلفون: Rodrigo R.R. Duarte, Sandrine Thuret, Timothy R. Powell, Demelza Smeeth, Ioanna Kourouzidou

المصدر: Neuroscience

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, prolactin, medicine.drug_class, Neurogenesis, 4-OHT, 4-hydroxytamoxifen, Biology, Hippocampal formation, Hippocampus, PRLR, prolactin receptor, 03 medical and health sciences, DCX, Doublecortin, MAP2, microtubule-associated protein 2, 0302 clinical medicine, Internal medicine, estradiol, medicine, AHN, adult hippocampal neurogenesis, Animals, Humans, Testosterone, ESR1, Estrogen Receptor 1, Progenitor cell, neural stem cells, Cell Proliferation, ESR2, Estrogen Receptor 2, General Neuroscience, HPC, hippocampal progenitor cell, Estrogens, BrdU, Bromodeoxyuridine, hippocampal neurogenesis, Neural stem cell, Prolactin, Doublecortin, 030104 developmental biology, Endocrinology, Bromodeoxyuridine, Estrogen, embryonic structures, biology.protein, ICC, immunocytochemistry, AR, androgen receptor, Female, 030217 neurology & neurosurgery, hormones, hormone substitutes, and hormone antagonists, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79be9ca5ba6757d62536be1fef095375Test
http://europepmc.org/articles/PMC7839971Test

3

A conformation-specific antibody against oligomeric β-amyloid restores neuronal integrity in a mouse model of Alzheimer's disease

المؤلفون: Michael R. Sierks, Ping He, Philip Schulz

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Biochemistry, Mice, Amyloid precursor protein, scFv, single chain antibody variable domain fragment, Neurons, biology, Chemistry, oligomeric beta amyloid, Neurogenesis, DCX, doublecortin, Brain, Editors' Pick, Alzheimer's disease, Cell biology, BBB, blood brain barrier, medicine.anatomical_structure, Disease Progression, SYP, synaptophysin, AD, Alzheimer's disease, Intracellular, Research Article, Genetically modified mouse, Aβ, amyloid β, rAAV, recombinant human adeno-associated virus, transgenic mice, Blood–brain barrier, Protein Aggregation, Pathological, 03 medical and health sciences, MAP2, microtubule-associated protein 2, Alzheimer Disease, APP, amyloid precursor protein, medicine, Animals, Humans, ApoB, apolipoprotein B, Molecular Biology, Neuroinflammation, Amyloid beta-Peptides, 030102 biochemistry & molecular biology, GFAP, glial fibrillary acidic protein, Cell Biology, medicine.disease, neuron, Disease Models, Animal, ND, nondementia, 030104 developmental biology, single-chain antibody, biology.protein, Neuron, Single-Chain Antibodies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb895cc10e4d58759d80fdf7e5d922ccTest
http://europepmc.org/articles/PMC7948963Test

4

A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy

المؤلفون: Ygberg, Sofia, Akkuratov, Evgeny E., Howard, Rebecca J., Taylan, Fulya, Jans, Daniel C., Mahato, Dhani R., Katz, Adriana, Kinoshita, Paula F., Portal, Benjamin, Nennesmo, Inger, Lindskog, Maria, Karlish, Steven J.D., Andersson, Magnus, Lindstrand, Anna, Brismar, Hjalmar, Aperia, Anita

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Xenopus, OS, ouabain-sensitive, Drug Resistance, Mutation, Missense, Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy), Molecular Dynamics Simulation, leak channel, MAP2, microtubule-associated protein 2, ExAC, Exome Aggregation Consortium, CADD, combined annotation-dependent depletion, Animals, Humans, OR, ouabain-resistant, WGS, whole-genome sequencing, Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci), Cells, Cultured, GFP, green fluorescent protein, DOPC, dioleoylphosphatidylcholine, Epilepsy, SNV, single nucleotide variant, Biochemistry and Molecular Biology, Brain, Infant, Editors' Pick, de novo mutation, Protein Subunits, Na,K-ATPase, arginine mutation, Anticonvulsants, Sodium-Potassium-Exchanging ATPase, MRI, magnetic resonance imaging, Biokemi och molekylärbiologi, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6615120c02b9832d8234c4ac3ea9f8e2Test
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190109Test

5

Tea polyphenols attenuate staurosporine-induced cytotoxicity and apoptosis by modulating BDNF-TrkB/Akt and Erk1/2 signaling axis in hippocampal neurons

المؤلفون: Xiao-Yan Qin, Teng-Teng Ren, Jian-Rong Yang, Rongfeng Lan

المصدر: IBRO Reports
IBRO Reports, Vol 8, Iss, Pp 115-121 (2020)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, ECG, (-)-epigallocatechin, Neurite, EGCG, (-)-epigallocatechin-3-gallate, Tropomyosin receptor kinase B, MAP2, Neuroprotection, Article, lcsh:RC321-571, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Erk1/2, medicine, Staurosporine, TUNEL, terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling, STS, staurosporine, Protein kinase B, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, LDH, Lactate dehydrogenase, EC, (-)-epicatechin, EGC, (-)-epicatechin-3-gallate, Chemistry, General Neuroscience, MAP2, microtubule associated protein 2, LY, LY294002, Cell biology, 030104 developmental biology, K252a, nervous system, PD98059, Apoptosis, LY294002, TP, tea polyphenols, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f84db80f237ce710df054b979fd086Test
https://pubmed.ncbi.nlm.nih.gov/32373755Test

6

Morphological alterations induced by the exposure to TiO2 nanoparticles in primary cortical neuron cultures and in the brain of rats

المؤلفون: Denis Nonclercq, Annica Frau, Sophie Laurent, Paula Paci, Dimitri Stanicki, Pascaline Rugira, Laurence Ris, Xavier Valentini, Pauline Deneufbourg

المصدر: Toxicology Reports
Toxicology Reports, Vol 5, Iss, Pp 878-889 (2018)

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Proliferation, BrdU, 5-Bromo-2′-deoxyuridine, 02 engineering and technology, 010501 environmental sciences, Toxicology, TNF-α, tumor necrosis factor-α, 01 natural sciences, NOS, nitric oxide synthase, DLS, dynamic light scattering, education.field_of_study, Chemistry, Brain, IL-10, interleukin-10, 021001 nanoscience & nanotechnology, Cell biology, medicine.anatomical_structure, medicine.symptom, IP, intraperitoneal, 0210 nano-technology, Astrocyte, IL-1β, interleukin-1β, ATP, adenosine triphosphate, BBB, blood-brain barrier, Central nervous system, Population, SEM, standard error of the mean, CNS, central nervous system, Blood–brain barrier, Article, MAP2, microtubule-associated protein 2, ROS, reactive oxygen species, FBS, fetal bovine serum, Neuroblast, lcsh:RA1190-1270, 4-HNE, 4-hydroxynonenal, Subependymal zone, medicine, education, NPs, nanoparticles, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, MDA, malondialdehyde, NO, nitric oxide, Neuroblast proliferation, NMDA, N-methyl-D-aspartate, GFAP, glial fibrillary acidic protein, technology, industry, and agriculture, nervous system, Gliosis, HBSS, Hank's balanced salt solution, Oxidative stress, Nanoparticles, Cell culture

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e90e8922a618aff4ce8cc2c337c8e6Test
https://doi.org/10.1016/j.toxrep.2018.08.006Test

7

Bi-directionally protective communication between neurons and astrocytes under ischemia

المؤلفون: Yick-Chun Yan, Christopher Qian, Fa-Li Zhang, Yu-Fu Zhou, Xiao-Mei Wu, Qian-Qian Luo, Li-Rong Jiang, Ya Ke, Zhong-Ming Qian, Wing-Ho Yung

المصدر: Redox Biology
Redox Biology, Vol 13, Iss C, Pp 20-31 (2017)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Pathology, Clinical Biochemistry, STAT5, signal transducer and activator of transcription 5, Cell Communication, Biochemistry, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Bi-directional communication, STAT5 Transcription Factor, lcsh:QH301-705.5, STAT5, Cells, Cultured, IP, ischmia-preconditionning, Neurons, lcsh:R5-920, TUNEL assay, Mitogen-Activated Protein Kinase 3, PI3K, phosphatidylinositol 3-kinase, Glutathione, Cell Hypoxia, Cell biology, JAK-2, Janus kinase-2, medicine.anatomical_structure, rhEPO, recombinant human EPO, IPcNCM, ischemia-preconditioned neuron culture medium, KA, kainic acid, lcsh:Medicine (General), Astrocyte, Research Paper, Cell signaling, medicine.medical_specialty, Kainic acid, MTT, 3-(4,5-dimethylthazol-2-yl)-2,5-diphenyltetrazolinum bromide, Astro-protection, Ischemia, GFAP, glial fibrillary acadic protein, DNA Fragmentation, Biology, CNS, central nervous system, 03 medical and health sciences, MAP2, microtubule-associated protein 2, In vivo, medicine, Animals, L-Lactate Dehydrogenase, Organic Chemistry, medicine.disease, OGD, oxygen glucose deprivation, Rats, Oxygen, 030104 developmental biology, chemistry, lcsh:Biology (General), Astrocytes, HIF-1alpha, hypoxia-inducible factor-1 alpha, biology.protein, EPO, erythropoietin, Reactive Oxygen Species, 030217 neurology & neurosurgery, Anti-apoptosis and anti-oxidant

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe9ac220012a9ec3c08b04e07de71d1Test
http://europepmc.org/articles/PMC5447396Test

8

A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways

المؤلفون: Gisela Helfer, Peter McCaffery, Robert Starr, Patrick N. Stoney, Dagmara Kociszewska, Peter J. Morgan, Anna Ashton, Thabat Khatib, Diana Rodrigues, Elizabeth A. Hay

المصدر: Brain, Behavior, and Immunity

مصطلحات موضوعية: Lipopolysaccharides, 0301 basic medicine, Retinoic acid, HDAC, histone deacetylase, Retinoic acid receptor beta, SD, short-day, Rats, Sprague-Dawley, Behavioral Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, RARE, retinoic acid response element, Gene expression, Transcriptional regulation, Bdnf, brain derived neurotrophic factor, Nrgn, neurogranin, skin and connective tissue diseases, TNFα, tumour necrosis factor alpha, Inflammatory, Full-length Article, Neurons, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, NF-kappa B, LCoR, ligand-dependent corepressor, cAMP, cyclic adenosine monophosphate, LPS, lipopolysaccharide, qPCR, quantitative polymerase chain reaction, Seasons, Dio, deiodinase, Signal transduction, Iba1, ionized calcium-binding adapter molecule 1, AP-1, activator protein-1, TSH, thyroid-stimulating hormone, Signal Transduction, LD, long-day, Photoperiod, Ependymoglial Cells, Immunology, PBS, phosphate-buffered saline, Hypothalamus, Prkc, protein kinase C, Lipopolysaccharide, Biology, DMEM, Dulbecco’s modified eagle medium, THR, thyroid hormone receptor, Nucleus, Histone Deacetylases, Cell Line, Tumour necrosis factor alpha, MAP2, microtubule-associated protein 2, 03 medical and health sciences, TRE, thyroid hormone response element, Animals, HSP90, heat-shock protein 90, Histone deacetylase, Inflammation, T3, triiodothyronine, Tumor Necrosis Factor-alpha, Endocrine and Autonomic Systems, GFAP, glial fibrillary acidic protein, Ptp1b, protein-tyrosine phosphatase 1B, HDAC4, Rats, Inbred F344, Rats, 030104 developmental biology, Gene Expression Regulation, Nuclear receptor, chemistry, Cancer research, sense organs, 030217 neurology & neurosurgery, RAR α, β and γ, retinoic acid receptor alpha, beta and gamma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce296684f37d082aef44268c3ea90416Test
https://doi.org/10.1016/j.bbi.2016.12.013Test

9

Trehalose does not improve neuronal survival on exposure to alpha-synuclein pre-formed fibrils

المؤلفون: Jianhua Zhang, Matthew Redmann, Victor M. Darley-Usmar, Laura A. Volpicelli-Daley, Willayat Yousuf Wani

المصدر: Redox Biology
Redox Biology, Vol 11, Iss, Pp 429-437 (2017)

مصطلحات موضوعية: 0301 basic medicine, Autophagosome, Tre, trehalose, DIV, days in vitro, Parkinson's disease, Clinical Biochemistry, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, CQ, chloroquine, Apoptosis, DMSO, dimethyl sulfoxide, Biochemistry, PD, Parkinson's disease, chemistry.chemical_compound, PVDF, polyvinylidene difluoride, Mice, LAMP1, lysosomal-associated membrane protein 1, TFEB, transcription factor EB, lcsh:QH301-705.5, Penn/Strep, Penicillin/Streptomycin, Neurons, lcsh:R5-920, LC3, microtubule-associated proteins 1 light chain 3, TOR Serine-Threonine Kinases, Neurodegeneration, E. coli, Escherichia coli, LAMP2A, lysosome-associated membrane protein 2A, Parkinson Disease, p-αSyn, phosphorylated-α-synuclein, Cell biology, PLL, poly-l-lysine, p-S129, phosphorylated serine 129, Pon S, ponceau S, MTT, 3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide), alpha-Synuclein, US FDA, United States Food and Drug Administration, lcsh:Medicine (General), Intracellular, Research Paper, Programmed cell death, Cell Survival, mTOR, mammalian target of rapamycin, P-alpha-synuclein trehalose, Biology, HMW, high molecular weight, αSyn, α-synuclein, Protein Aggregation, Pathological, 03 medical and health sciences, MAP2, microtubule-associated protein 2, FBS, fetal bovine serum, PBS, phosphate buffered saline, medicine, Autophagy, HSC70, heat shock cognate 70, PFFs, pre-formed fibrils, WT, wildtype, Animals, Humans, RIPA, radioimmunoprecipitation assay buffer, PI3K/AKT/mTOR pathway, KO, knockout, Organic Chemistry, GFAP, glial fibrillary acidic protein, Trehalose, Alpha-synuclein fibrils, medicine.disease, 030104 developmental biology, chemistry, lcsh:Biology (General), TX-100, triton X-100, LC3-II, AraC, cytosine arabinoside, SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis, ICC, immunocytochemistry, TFEB, BSA, bovine serum albumin, Con, control, HSP104, heat shock protein 104

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42b1d52df123718bbc2aac88a0c0e7fTest
http://europepmc.org/articles/PMC5220183Test

10

Stem cell fate determination through protein O-GlcNAcylation

المؤلفون: Bright Starling Emerald, Muhammad Abid Sheikh, Suraiya A. Ansari

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, MSCs, mesenchymal stem cells, TET, ten-eleven translocation, Biochemistry, Epigenesis, Genetic, O-GlcNAcylation, hPSCs, human pluripotent stem cells, Gene Regulatory Networks, NTDs, neural tube defects, SAM, S-adenosyl methionine, Induced pluripotent stem cell, Uridine Diphosphate N-Acetylglucosamine, Stem Cells, iPSCs, induced pluripotent stem cells, Cell biology, NDDs, neurodevelopmental disorders, Stem cell fate commitment, Stem cell, transcription, MHC, myosin heavy chain, Adult stem cell, Reviews, PPP, pentose phosphate pathway, PTM, posttranslational modifications, Cell fate determination, Biology, MAP2, microtubule-associated protein 2, 03 medical and health sciences, ROS, reactive oxygen species, SOD, superoxide dismutase, Animals, Humans, Cell Lineage, Epigenetics, Molecular Biology, epigenetics, DON, 6-diazo-5-oxo-norleucine, 030102 biochemistry & molecular biology, HSCs, hematopoietic stem cells, Proteins, ESCs, embryonic stem cells, OGT, O-GlcNAc transferase, Cell Biology, Embryonic stem cell, HBP, hexosamine biosynthesis pathway, 030104 developmental biology, Stem cell fate determination, OGA, O-GlcNAcase, gene expression, cell fate determination, ODD, oxygen-dependent degradation, Protein Processing, Post-Translational

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e46bbaeb35f21f9e3b8a1455d9c0910Test
https://doi.org/10.1074/jbc.rev120.014915Test

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