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1دورية أكاديمية
المؤلفون: Geetika Singh, Cristina D. Guibao, Jayaraman Seetharaman, Anup Aggarwal, Christy R. Grace, Dan E. McNamara, Sivaraja Vaithiyalingam, M. Brett Waddell, Tudor Moldoveanu
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
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2دورية أكاديميةDynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
المؤلفون: Maksym Tsytlonok, Hugo Sanabria, Yuefeng Wang, Suren Felekyan, Katherina Hemmen, Aaron H. Phillips, Mi-Kyung Yun, M. Brett Waddell, Cheon-Gil Park, Sivaraja Vaithiyalingam, Luigi Iconaru, Stephen W. White, Peter Tompa, Claus A. M. Seidel, Richard Kriwacki
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2041-1723Test
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المؤلفون: Philip M. Potter, Anang A. Shelat, Stephen W. White, R. Kiplin Guy, Daniel Savic, Taosheng Chen, Martine F. Roussel, Marie Morfouace, Richard E. Lee, Jun Yang, Vincent A. Boyd, Nagakumar Bharatham, Brandon M. Young, Jeanine E. Price, Jonathan A. Low, Kevin W. Freeman, Rachelle R. Olsen, William R. Shadrick, Zhenmei Li, Geoffrey Neale, Sourav Das, M. Brett Waddell, Michele Connelly, Sergio C. Chai, Barbara Jonchere, Nancy E. Martinez, Lyudmila Tsurkan, Mi-Kyung Yun, Liying Chi, P. Jake Slavish
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5d71e4e32bd0d5208d4d9130ecd2d2Test
https://doi.org/10.1158/0008-5472.c.6511882.v1Test -
4Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer
المؤلفون: Barbara Jonchere, Jonathan Low, Michele Connelly, Liying Chi, Sergio C. Chai, R. Kiplin Guy, Kevin W. Freeman, Brandon Young, Jeanine E. Price, Mi-Kyung Yun, Marie Morfouace, Anang A. Shelat, Geoffrey Neale, Rachelle R. Olsen, Nagakumar Bharatham, Daniel Savic, Stephen W. White, P. Jake Slavish, Vincent A. Boyd, Lyudmila Tsurkan, Jun J. Yang, Nancy E. Martinez, Zhenmei Li, Martine F. Roussel, Philip M. Potter, M. Brett Waddell, William R. Shadrick, Richard E. Lee, Taosheng Chen, Sourav Das
المصدر: Cancer Res
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antineoplastic Agents, Context (language use), Mice, SCID, Article, Proto-Oncogene Proteins c-myc, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Cell Line, Tumor, Neoplasms, Neuroblastoma, medicine, Animals, Humans, Child, Cytotoxicity, Oncogene, Chemistry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Pediatric cancer, Bromodomain, 030104 developmental biology, Oncology, Drug development, Drug Design, 030220 oncology & carcinogenesis, Cancer research, Female, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d687ae06b408a0a8a364651477a03fTest
https://doi.org/10.1158/0008-5472.can-19-3934Test -
5دورية أكاديمية
المؤلفون: Steven W Paugh, David R Coss, Ju Bao, Lucas T Laudermilk, Christy R Grace, Antonio M Ferreira, M Brett Waddell, Granger Ridout, Deanna Naeve, Michael Leuze, Philip F LoCascio, John C Panetta, Mark R Wilkinson, Ching-Hon Pui, Clayton W Naeve, Edward C Uberbacher, Erik J Bonten, William E Evans
المصدر: PLoS Computational Biology, Vol 12, Iss 2, p e1004744 (2016)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
العلاقة: http://europepmc.org/articles/PMC4742280?pdf=renderTest; https://doaj.org/toc/1553-734XTest; https://doaj.org/toc/1553-7358Test
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المؤلفون: Prashasti Kumar, Pratul K. Agarwal, M. Brett Waddell, Tanja Mittag, Engin H. Serpersu, Matthew J. Cuneo
المصدر: Angewandte Chemie. 131:16406-16412
مصطلحات موضوعية: General Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cbeac05486bf96cebd4a03134337defcTest
https://doi.org/10.1002/ange.201908535Test -
7دورية أكاديميةDesign, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction.
المؤلفون: Mariell Pettersson, Maria Quant, Jaeki Min, Luigi Iconaru, Richard W Kriwacki, M Brett Waddell, R Kiplin Guy, Kristina Luthman, Morten Grøtli
المصدر: PLoS ONE, Vol 10, Iss 10, p e0137867 (2015)
وصف الملف: electronic resource
العلاقة: http://europepmc.org/articles/PMC4591261?pdf=renderTest; https://doaj.org/toc/1932-6203Test
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8دورية أكاديمية
المؤلفون: Judith Souphron, M. Brett Waddell, Amir Paydar, Zeynep Tokgöz-gromley, O Martine, F. Roussel, Brenda A. Schulman
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/a6/e1/Biochemistry_2008_Aug_26_47(34)_8961-8969.tar.gz
وصف الملف: application/zip
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المؤلفون: Tanja Mittag, Pratul K. Agarwal, Engin H. Serpersu, M. Brett Waddell, Matthew J. Cuneo, Prashasti Kumar
المصدر: Angewandte Chemie (International ed. in English). 58(45)
مصطلحات موضوعية: Hydrogen, Protein Conformation, Low-barrier hydrogen bond, Static Electricity, chemistry.chemical_element, Molecular Dynamics Simulation, 010402 general chemistry, Crystallography, X-Ray, 01 natural sciences, Catalysis, Enzyme catalysis, Acetyltransferases, Catalytic Domain, Catalytic triad, Humans, Binding Sites, biology, 010405 organic chemistry, Chemistry, Hydrogen bond, Active site, Hydrogen Bonding, General Chemistry, Hydrogen atom, 0104 chemical sciences, Anti-Bacterial Agents, Crystallography, Aminoglycosides, biology.protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc82b97736c769085cfafb3ceb23f41bTest
https://pubmed.ncbi.nlm.nih.gov/31515870Test -
10Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
المؤلفون: Mi-Kyung Yun, Maksym Tsytlonok, Peter Tompa, Sivaraja Vaithiyalingam, Suren Felekyan, Claus A. M. Seidel, Aaron H. Phillips, Luigi I. Iconaru, Yuefeng Wang, Hugo Sanabria, Stephen W. White, M. Brett Waddell, Richard W. Kriwacki, Katherina Hemmen, Cheon-Gil Park
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communicationsمصطلحات موضوعية: Threonine, 0301 basic medicine, Quantitative Biology - Subcellular Processes, Cell division, Cyclin A, Fusion Proteins, bcr-abl, General Physics and Astronomy, 02 engineering and technology, Crystallography, X-Ray, Quantitative Biology - Quantitative Methods, chemistry.chemical_compound, Phosphorylation, lcsh:Science, Quantitative Methods (q-bio.QM), Multidisciplinary, biology, Chemistry, 021001 nanoscience & nanotechnology, Recombinant Proteins, Cell biology, src-Family Kinases, 0210 nano-technology, Tyrosine kinase, Cell Division, Cyclin-Dependent Kinase Inhibitor p27, Protein Binding, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src, Science, Molecular Dynamics Simulation, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cyclin-dependent kinase, Subcellular Processes (q-bio.SC), Cyclin-Dependent Kinase 2, Cyclin-dependent kinase 2, Tyrosine phosphorylation, Biomolecules (q-bio.BM), General Chemistry, Protein Structure, Tertiary, 030104 developmental biology, Quantitative Biology - Biomolecules, FOS: Biological sciences, Proteolysis, Mutagenesis, Site-Directed, biology.protein, Tyrosine, lcsh:Q, Protein Processing, Post-Translational
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebf5b582a25ff50bd576925e3ed1b6aTest
http://arxiv.org/abs/1812.07009Test