Expression of the inhibitor of DNA-binding (ID)-1 protein as an angiogenic mediator in tumour advancement of uterine cervical cancers
العنوان: | Expression of the inhibitor of DNA-binding (ID)-1 protein as an angiogenic mediator in tumour advancement of uterine cervical cancers |
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المؤلفون: | Teruhiko Tamaya, Jiro Fujimoto, M K Maw |
المصدر: | British Journal of Cancer |
بيانات النشر: | Nature Publishing Group, 2009. |
سنة النشر: | 2009 |
مصطلحات موضوعية: | Adult, Inhibitor of Differentiation Protein 1, Pathology, medicine.medical_specialty, Cancer Research, Angiogenesis, Uterine Cervical Neoplasms, Adenocarcinoma, angiogenesis, Clinical Studies, Biomarkers, Tumor, Medicine, Humans, RNA, Messenger, Microvessel, Survival rate, Survival analysis, Aged, Cervical cancer, Neovascularization, Pathologic, business.industry, Angiogenesis Modulating Agents, Cancer, Middle Aged, medicine.disease, Prognosis, Survival Analysis, prognostic indicator, Oncology, Carcinoma, Squamous Cell, Disease Progression, Immunohistochemistry, Female, business, ID-1, tumour advancement, Corrigendum, uterine cervical cancer |
الوصف: | The ID protein, an inhibitor of basic helix-loop-helix (HLH) transcription factors, has been involved in multiple cellular processes. To investigate the association between tumour advancement and ID expressions of uterine cervical cancers, the levels of ID-1, ID-2 and ID-3 mRNAs were determined by real-time reverse transcription-polymerase chain reaction and the histoscore with the localisation of ID-1 was determined by immunohistochemistry and patient survival in 60 patients. ID-1 histoscores and mRNA levels both significantly (P |
اللغة: | English |
تدمد: | 1532-1827 0007-0920 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32995e52550d5cdb1395c88e5b39350bTest http://europepmc.org/articles/PMC2720194Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....32995e52550d5cdb1395c88e5b39350b |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15321827 00070920 |
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