يعرض 1 - 10 نتائج من 706 نتيجة بحث عن '"Lushchekina A."', وقت الاستعلام: 1.09s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer’s Disease

    المؤلفون: Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Sofya V. Lushchekina, Tatiana Y. Astakhova, Elena N. Timokhina, Igor V. Serkov, Alexey N. Proshin, Yuliya V. Soldatova, Darya A. Poletaeva, Irina I. Faingold, Viktoriya A. Mumyatova, Alexey A. Terentiev, Eugene V. Radchenko, Vladimir A. Palyulin, Sergey O. Bachurin, Rudy J. Richardson

    المصدر: Molecules, Vol 29, Iss 2, p 321 (2024)

    مصطلحات موضوعية: Alzheimer’s disease (AD), 4-amino-2,3-polymethylenequinolines, butylated hydroxytoluene (BHT), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), antioxidants, Organic chemistry, QD241-441

    العلاقة: https://www.mdpi.com/1420-3049/29/2/321Test; https://doaj.org/toc/1420-3049Test; https://doaj.org/article/9dc8029bd61a4fcb9dc34956137feaf5Test

    الإتاحة: https://doi.org/10.3390/molecules29020321Test
    https://doaj.org/article/9dc8029bd61a4fcb9dc34956137feaf5Test

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  2. 2
    دورية أكاديمية
    Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer’s disease

    المؤلفون: Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Sofya V. Lushchekina, Tatiana Yu Astakhova, Elena N. Timokhina, Olga G. Serebryakova, Alexander V. Shchepochkin, Maxim A. Averkov, Irina A. Utepova, Nadezhda S. Demina, Eugene V. Radchenko, Vladimir A. Palyulin, Vladimir P. Fisenko, Sergey O. Bachurin, Oleg N. Chupakhin, Valery N. Charushin, Rudy J. Richardson

    المصدر: Frontiers in Pharmacology, Vol 14 (2023)

    مصطلحات موضوعية: 9-phosphoryl-9,10-dihydroacridines, 9-phosphorylacridines, acetylcholinesterase, butyrylcholinesterase, Alzheimer’s disease, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2023.1219980/fullTest; https://doaj.org/toc/1663-9812Test

    الوصول الحر: https://doaj.org/article/19995bc7cc79494d8334518aebc4070eTest

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  3. 3
    دورية أكاديمية
    Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer’s disease

    المؤلفون: Makhaeva, G. F., Kovaleva, N. V., Rudakova, E. V., Boltneva, N. P., Lushchekina, S. V., Astakhova, T. Y., Timokhina, E. N., Serebryakova, O. G., Shchepochkin, A. V., Averkov, M. A., Utepova, I. A., Demina, N. S., Radchenko, E. V., Palyulin, V. A., Fisenko, V. P., Bachurin, S. O., Chupakhin, O. N., Charushin, V. N., Richardson, R. J.

    المصدر: Frontiers in Pharmacology

    مصطلحات موضوعية: 9-PHOSPHORYL-9,10-DIHYDROACRIDINES, 9-PHOSPHORYLACRIDINES, ACETYLCHOLINESTERASE, ALZHEIMER’S DISEASE, BUTYRYLCHOLINESTERASE, 9 PHOSPHORYL 9,10 DIHYDROACRIDINES, 9 PHOSPHORYLACRIDINES, ACRIDINE DERIVATIVE, AMYLOID BETA PROTEIN, ANTIOXIDANT, CARBOXYLESTERASE, CHOLINESTERASE, CHOLINESTERASE INHIBITOR, UNCLASSIFIED DRUG, ABTS RADICAL SCAVENGING ASSAY, ALZHEIMER DISEASE, ANTIOXIDANT ACTIVITY, ARTICLE, ASSAY, BLOOD BRAIN BARRIER, CARDIOTOXICITY, DRUG PENETRATION, ENZYME ACTIVITY, ENZYME INHIBITION, FERRIC REDUCING ANTIOXIDANT POWER, FERRIC REDUCING ANTIOXIDANT POWER ASSAY, FLUORESCENCE INTENSITY, HIGH TEMPERATURE PROCEDURES, HUMAN, IN VITRO STUDY

    وصف الملف: application/pdf

    العلاقة: Makhaeva, G, Kovaleva, N, Rudakova, E, Boltneva, N, Lushchekina, S, Astakhova, T, Timokhina, E, Serebryakova, O, Shchepochkin, A, Averkov, M, Utepova, I, Demina, N, Radchenko, E, Palyulin, V, Fisenko, VP, Bachurin, S, Chupakhin, O, Charushin, V & Richardson, R 2023, 'Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer’s disease', Frontiers in Pharmacology, Том. 14, 1219980. https://doi.org/10.3389/fphar.2023.1219980Test; Makhaeva, G., Kovaleva, N., Rudakova, E., Boltneva, N., Lushchekina, S., Astakhova, T., Timokhina, E., Serebryakova, O., Shchepochkin, A., Averkov, M., Utepova, I., Demina, N., Radchenko, E., Palyulin, V., Fisenko, V. P., Bachurin, S., Chupakhin, O., Charushin, V., & Richardson, R. (2023). Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer’s disease. Frontiers in Pharmacology, 14, [1219980]. https://doi.org/10.3389/fphar.2023.1219980Test; Final; All Open Access, Gold, Green; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85169578072&doi=10.3389%2ffphar.2023.1219980&partnerID=40&md5=e5a9703fe921a2849ee1d5766d8a9381Test; https://www.frontiersin.org/articles/10.3389/fphar.2023.1219980/pdfTest; http://elar.urfu.ru/handle/10995/130756Test; 85169578072; 001057900600001

    الإتاحة: https://doi.org/10.3389/fphar.2023.1219980Test
    http://elar.urfu.ru/handle/10995/130756Test

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  4. 4
    دورية أكاديمية
    Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease

    المؤلفون: Makhaeva, G. F., Kovaleva, N. V., Rudakova, E. V., Boltneva, N. P., Grishchenko, M. V., Lushchekina, S. V., Astakhova, T. Y., Serebryakova, O. G., Timokhina, E. N., Zhilina, E. F., Shchegolkov, E. V., Ulitko, M. V., Radchenko, E. V., Palyulin, V. A., Burgart, Y. V., Saloutin, V. I., Bachurin, S. O., Richardson, R. J.

    المصدر: International Journal of Molecular Sciences

    مصطلحات موضوعية: ACETYLCHOLINESTERASE, ADMET PREDICTION, ALZHEIMER’S DISEASE, ANTIOXIDANT ACTIVITY, AΒ42 SELF-AGGREGATION, BUTYRYLCHOLINESTERASE, METAL CHELATION, PROPIDIUM DISPLACEMENT, SALICYLIC ACID DERIVATIVES, TACRINE CONJUGATES, 2 METHYL N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYL]BENZAMIDE, 2 METHYL N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYL]BENZAMIDE, 2 METHYL N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYL]BENZAMIDE, 2 [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYLIMINOMETHYL]PHENOL, 2 [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYLIMINOMETHYL]PHENOL, 2 [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYLIMINOMETHYL]PHENOL, 4,5 DIFLUORO 2 HYDROXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYL]BENZAMIDE, 4,5 DIFLUORO 2 HYDROXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYL]BENZAMIDE, 4,5 DIFLUORO 2 HYDROXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYL]BENZAMIDE, 4,5 DIFLUORO 2 METHOXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYL]BENZAMIDE, 4,5 DIFLUORO 2 METHOXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYL]BENZAMIDE, 4,5 DIFLUORO 2 METHOXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYL]BENZAMIDE, AMYLOID BETA PROTEIN[1-42], ANTIOXIDANT, ASCORBIC ACID, CHELATING AGENT, CHOLINESTERASE, CHOLINESTERASE INHIBITOR, COPPER, DONEPEZIL

    وصف الملف: application/pdf

    العلاقة: Makhaeva, GF, Kovaleva, NV, Rudakova, EV, Boltneva, NP, Grishchenko, MV, Lushchekina, SV, Astakhova, TY, Serebryakova, OG, Timokhina, EN, Zhilina, EF, Shchegolkov, EV, Ulitko, MV, Radchenko, EV, Palyulin, VA, Burgart, YV, Saloutin, VI, Bachurin, SO & Richardson, RJ 2023, 'Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease', International Journal of Molecular Sciences, Том. 24, № 3, 2285. https://doi.org/10.3390/ijms24032285Test; Makhaeva, G. F., Kovaleva, N. V., Rudakova, E. V., Boltneva, N. P., Grishchenko, M. V., Lushchekina, S. V., Astakhova, T. Y., Serebryakova, O. G., Timokhina, E. N., Zhilina, E. F., Shchegolkov, E. V., Ulitko, M. V., Radchenko, E. V., Palyulin, V. A., Burgart, Y. V., Saloutin, V. I., Bachurin, S. O., & Richardson, R. J. (2023). Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease. International Journal of Molecular Sciences, 24(3), [2285]. https://doi.org/10.3390/ijms24032285Test; Final; All Open Access, Gold, Green; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85148003235&doi=10.3390%2fijms24032285&partnerID=40&md5=fe6438dda642e3160d82a1abfe2c8c8bTest; https://www.mdpi.com/1422-0067/24/3/2285/pdf?version=1675907905Test; http://elar.urfu.ru/handle/10995/130201Test; 85148003235; 000935706300001

    الإتاحة: https://doi.org/10.3390/ijms24032285Test
    http://elar.urfu.ru/handle/10995/130201Test
    https://www.mdpi.com/1422-0067/24/3/2285/pdf?version=1675907905Test

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  5. 5
    دورية أكاديمية
    Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease

    المؤلفون: Galina F. Makhaeva, Nadezhda V. Kovaleva, Elena V. Rudakova, Natalia P. Boltneva, Maria V. Grishchenko, Sofya V. Lushchekina, Tatiana Y. Astakhova, Olga G. Serebryakova, Elena N. Timokhina, Ekaterina F. Zhilina, Evgeny V. Shchegolkov, Mariya V. Ulitko, Eugene V. Radchenko, Vladimir A. Palyulin, Yanina V. Burgart, Victor I. Saloutin, Sergey O. Bachurin, Rudy J. Richardson

    المصدر: International Journal of Molecular Sciences; Volume 24; Issue 3; Pages: 2285

    مصطلحات موضوعية: Alzheimer’s disease, acetylcholinesterase, butyrylcholinesterase, salicylic acid derivatives, tacrine conjugates, propidium displacement, Aβ 42 self-aggregation, antioxidant activity, metal chelation, ADMET prediction

    جغرافية الموضوع: agris

    وصف الملف: application/pdf

    العلاقة: Biochemistry; https://dx.doi.org/10.3390/ijms24032285Test

    الإتاحة: https://doi.org/10.3390/ijms24032285Test

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  6. 6
    دورية أكاديمية
    Genetic Consequences of the Dramatic Decline in the Northwest Pre-Caspian Saiga (Saiga tatarica tatarica) Population: A Comparison of Modern and Museum Samples on mtDNA and Microsatellite Loci.

    المؤلفون: Kashinina, N. V.1 (AUTHOR) nadezda.kashinina@yandex.ru, Lushchekina, A. A.1 (AUTHOR), Sorokin, P. A.1 (AUTHOR), Kholodova, M. V.1 (AUTHOR)

    المصدر: Biology Bulletin. Aug2024, Vol. 51 Issue 4, p1083-1094. 12p.


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  7. 7
    دورية أكاديمية
    Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease

    المؤلفون: Sergey O. Bachurin, Elena F. Shevtsova, Galina F. Makhaeva, Alexey Yu. Aksinenko, Vladimir V. Grigoriev, Tatiana V. Goreva, Tatiana A. Epishina, Nadezhda V. Kovaleva, Natalia P. Boltneva, Sofya V. Lushchekina, Elena V. Rudakova, Darya V. Vinogradova, Pavel N. Shevtsov, Elena A. Pushkareva, Ludmila G. Dubova, Tatiana P. Serkova, Ivan M. Veselov, Vladimir P. Fisenko, Rudy J. Richardson

    المصدر: International Journal of Molecular Sciences, Vol 23, Iss 22, p 13925 (2022)

    مصطلحات موضوعية: conjugates, methylene blue, cycloalkaneindoles, multifunctional agents, neurodegenerative disease, cholinesterases, Biology (General), QH301-705.5, Chemistry, QD1-999

    وصف الملف: electronic resource

    العلاقة: https://www.mdpi.com/1422-0067/23/22/13925Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test

    الوصول الحر: https://doaj.org/article/bed9b9696c514d1caf241d2b10e8865dTest

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  8. 8
    دورية أكاديمية
    Novel Uracil-Based Inhibitors of Acetylcholinesterase with Potency for Treating Memory Impairment in an Animal Model of Alzheimer’s Disease

    المؤلفون: Vyacheslav E. Semenov, Irina V. Zueva, Sofya V. Lushchekina, Eduard G. Suleimanov, Liliya M. Gubaidullina, Marina M. Shulaeva, Oksana A. Lenina, Konstantin A. Petrov

    المصدر: Molecules, Vol 27, Iss 22, p 7855 (2022)

    مصطلحات موضوعية: acetylcholinesterase, 6-methyluracil, inhibitors, peripheral anionic site, Alzheimer’s disease, Organic chemistry, QD241-441

    وصف الملف: electronic resource

    العلاقة: https://www.mdpi.com/1420-3049/27/22/7855Test; https://doaj.org/toc/1420-3049Test

    الوصول الحر: https://doaj.org/article/76c4a99ab68949beb4f66f6db588bdb1Test

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  9. 9
    دورية أكاديمية
    On the chigger mite (Acariformes: Trombiculidae) fauna of Ethiopia.

    المؤلفون: Antonovskaia, Anastasia A.1,2 (AUTHOR), Lushchekina, Anna A.3 (AUTHOR), Lavrenchenko, Leonid A.4 (AUTHOR), Stekolnikov, Alexandr A.2 (AUTHOR) Alexandr.Stekolnikov@zin.ru

    المصدر: International Journal of Acarology. Feb2024, Vol. 50 Issue 1, p53-67. 15p.


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  10. 10
    دورية أكاديمية
    Conjugates of amiridine and thiouracil derivatives as effective inhibitors of butyrylcholinesterase with the potential to block β‐amyloid aggregation.

    المؤلفون: Khudina, Olga G., Grishchenko, Maria V., Makhaeva, Galina F., Kovaleva, Nadezhda V., Boltneva, Natalia P., Rudakova, Elena V., Lushchekina, Sofya V., Shchegolkov, Evgeny V., Borisevich, Sophia S., Burgart, Yanina V., Saloutin, Victor I., Charushin, Valery N.

    المصدر: Archiv der Pharmazie; Feb2024, Vol. 357 Issue 2, p1-20, 20p


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