Association of Fluid Overload With Clinical Outcomes in Critically Ill Children With Bronchiolitis: Bronquiolitis en la Unidad de Cuidados Intensivos Pediátricos (BRUCIP) Study
| العنوان: | Association of Fluid Overload With Clinical Outcomes in Critically Ill Children With Bronchiolitis: Bronquiolitis en la Unidad de Cuidados Intensivos Pediátricos (BRUCIP) Study |
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| المؤلفون: | Flores-González JC, Valladares CM, Yun Castilla C, Mayordomo-Colunga J, Quesada SP, Martín Delgado CM, Goñi-Orayen C, Fernández Carrión F, Veiga AM, Olmedilla-Jodar M, Alcaraz Romero AJ, Eizmendi-Bereciartua M, Gutierrez CS, Luján EA, Navarro-Mingorance Á, Jordán-García I, Bronquiolitis en la Unidad de Cuidados Intensivos Pediátricos (BRUCIP) WorkGroup |
| المصدر: | PEDIATRIC CRITICAL CARE MEDICINE r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu |
| بيانات النشر: | LIPPINCOTT WILLIAMS & WILKINS, 2019. |
| سنة النشر: | 2019 |
| الوصف: | OBJECTIVES: Increasing evidence supports the association of fluid overload with adverse outcomes in different diseases. To our knowledge, few studies have examined the impact of fluid balance on clinical outcome in severe bronchiolitis. Our aim was to determine whether fluid overload was associated with adverse clinical outcomes in critically ill children with severe bronchiolitis. DESIGN: Descriptive, prospective, multicenter study. SETTING: Sixteen Spanish PICUs. PATIENTS: Severe acute bronchiolitis who required admission from October 2014 to May 2015 were included. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Total fluid intake and output were prospectively recorded during PICU assistance. Fluid balance was measured at 24, 48, and 72 hours after PICU admission. A total of 262 patients were enrolled; 54.6% were male. Median age was 1 month (interquartile range, 1-3 mo). Patients had a positive fluid balance during the first 4 days of PICU admission, reaching a neutral balance on day 4. A positive balance at 24 hours in patients admitted to the PICU with severe bronchiolitis was related with longer stay in PICU (p < 0.001), longer hospital stay (p < 0.001), longer duration of mechanical ventilation (p = 0.016), and longer duration of noninvasive ventilation (p = 0.0029). CONCLUSIONS: Critically ill patients with severe acute bronchiolitis who present a positive balance in the first 24 hours of PICU admission have poorer clinical outcomes with longer PICU and hospital length of stay and duration of invasive and noninvasive mechanical ventilation. |
| تدمد: | 1529-7535 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b9792e68bfe14f6c2efdcef2809d6c67Test http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=15744Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.dedup.wf.001..b9792e68bfe14f6c2efdcef2809d6c67 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15297535 |
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