Presentation_1_Increased Amygdala-Paracentral Lobule/Precuneus Functional Connectivity Associated With Patients With Mood Disorder and Suicidal Behavior.pdf

التفاصيل البيبلوغرافية
العنوان: Presentation_1_Increased Amygdala-Paracentral Lobule/Precuneus Functional Connectivity Associated With Patients With Mood Disorder and Suicidal Behavior.pdf
المؤلفون: Ran Zhang (117374), Luheng Zhang (9989612), Shengnan Wei (2580193), Pengshuo Wang (6241568), Xiaowei Jiang (168623), Yanqing Tang (438986), Fei Wang (19534)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Neuroscience, Exercise Physiology, Central Nervous System, Computer Perception, Memory and Attention, Decision Making, Neurocognitive Patterns and Neural Networks, Music Therapy, mood disorder, suicidal behavior, fMRI—functional magnetic resonance imaging, functional connectivity, amygdala
الوصف: Mood disorder patients have greater suicide risk than members of the general population, but how suicidal behavior relates to brain functions has not been fully elucidated. This study investigated how functional connectivity (FC) values between the right/left amygdala and the whole brain relate to suicidal behavior in patients with mood disorder. The participants in this study were 100 mood disorder patients with suicidal behavior (SB group), 120 mood disorder patients with non-suicidal behavior (NSB group), and 138 age- and gender-matched healthy controls (HC group). Whole-brain FC values among the three groups were compared using an analysis of covariance (ANCOVA). Compared to the NSB and HC groups, increased FC values in the right amygdala-bilateral paracentral lobule/precuneus circuit were observed in the SB group (Bonferroni-corrected, p < 0.017). The FC values in the NSB group did not differ significantly from those in the HC group (Bonferroni-corrected, p > 0.017). Moreover, there were no significant differences in FC values between mood disorder patients with suicide attempt (SA group) and mood disorder patients with suicidal ideation (SI group), while the FC values between the right amygdala and bilateral paracentral lobule/precuneus in the SA group were higher than the mean in the SI group. These findings suggest that right amygdala-paracentral lobule/precuneus dysfunction has an important role in patients with mood disorder and suicidal behavior.
نوع الوثيقة: conference object
اللغة: unknown
العلاقة: https://figshare.com/articles/presentation/Presentation_1_Increased_Amygdala-Paracentral_Lobule_Precuneus_Functional_Connectivity_Associated_With_Patients_With_Mood_Disorder_and_Suicidal_Behavior_pdf/13579112Test
DOI: 10.3389/fnhum.2020.585664.s001
الإتاحة: https://doi.org/10.3389/fnhum.2020.585664.s001Test
حقوق: CC BY 4.0
رقم الانضمام: edsbas.F4CAA0A8
قاعدة البيانات: BASE